105 completed, 41 unknown, 22 recruiting, 15 not yet recruiting. 116 Not applicable, 22 Phase 2, 14 Phase 3, 11 Phase 1, 10 Phase 4.
Follow Sciatic Neuropathy: new trials by email Literature Review of Sciatic Neuropathy trials Research Report on Sciatic Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hypersound Treatment for Chronic Neuropathic and Radicular Pain Hypersound RF-PNS system, Sham Hypersound - Chronic Neuropathic Pain, Radiculopathy | Not applicable | Not yet recruiting | Hypersound Medical Inc | 71 | 2027-06-01 | 2026-09-21 |
| Corticosteroid Lumbar Epidural Analgesia for Radicular Pain 2 SP-102, Placebo, Dexamethasone Sodium Phosphate 10 MG/ML - Lumbosacral Radicular Pain | Phase 3 | Not yet recruiting | Semnur Pharmaceuticals, Inc. | 755 | 2027-02-01 | 2026-09-09 |
| Randomized Evaluation of Lumbar Injection Effectiveness and Function Triojection® System, Selective Nerve Root Block (SNRB) - Lumbar Radiculopathy, Lumbar Disc Herniation | Not applicable | Not yet recruiting | SpinaFX Medical Inc. | 300 | 2027-01-15 | 2026-10-07 |
| Efficacy of Botulinum Toxin Versus Placebo on Pain and Health Related Quality of Life of Patients With Piriformis Muscle Syndrome Botulinum Toxin - A injections, Placebo - Piriformis Muscle Syndrome | Phase 2 | Not yet recruiting | Centre Hospitalier Universitaire de Nīmes | 108 | 2027-01-01 | 2026-10-21 |
| Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome Ultrasound-Guided Piriformis Injection, Ultrasound-Guided Interfascial Hydrodissection, Standardized Home-Based Piriformis Stretching Program - Piriformis Syndrome | Not applicable | Recruiting | Haydarpasa Numune Training and Research Hospital | 110 | 2026-09-24 | 2026-09-28 |
| Effect of Transfer of Energy Capacitive and Resistive on Chronic Discogenic Sciatica Transfer of Energy Capacitive and Resistive (TECAR) therapy, conventional physical therapy program - Lumbar Radiculopathy | Not applicable | Recruiting | Cairo University | 34 | 2026-09-21 | 2026-09-28 |
| Dose Dependent Steroid Injections Triamcinolone 10 Mg/mL Injectable Suspension, Triamcinolone 40 Mg/mL Injectable Suspension, Triamcinolone 80 Mg/mL Injectable Suspension - Lumbar Radiculopathy, Sciatica | Phase 4 | Not yet recruiting | University of Miami | 150 | 2026-09-15 | 2026-08-12 |
| Strain-Counterstrain Treatment of Piriformis Pain Strain-Counterstrain treatment of piriformis muscle - Low Back Pain, Mechanical, Piriformis Syndrome | Not applicable | Recruiting | Loma Linda University | 30 | 2026-09-01 | 2026-04-24 |
| Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Radiculopathy Mirror Image Spine Correction Exercises, Conservative Physiotherapy - Radiculopathy, Radiculopathy Lumbar | Not applicable | Not yet recruiting | University of Sharjah | 64 | 2026-09-01 | 2026-04-30 |
| Effects of MET and MFR on Piriformis Syndrome Muscle Energy Technique, Myofascial Release Technique, Conventional Physical Therapy - Piriformis Syndrome | Not applicable | Not yet recruiting | Igdir University | 72 | 2026-08-30 | 2026-08-17 |
| Comparative Effects of Post-Isometric Relaxation and Reciprocal Inhibition Techniques inPiriformis Syndrome Post isometrics Relaxation Techniques (PIR), Reciprocal Inhibition Technique - Piriformis Syndrome | Not applicable | Recruiting | Riphah International University | 42 | 2026-08-01 | 2026-09-24 |
| Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study) triamcinolone acetonide (Kenalog), Celestone Soluspan 6Mg/Ml Suspension for Injection, Depo-Medrol 40Mg/Ml Suspension for Injection - Back Pain Lower Back, Neck Pain | Phase 4 | Recruiting | Igor Wilderman. MD | 500 | 2026-07-30 | 2026-08-13 |
| Comparing Two Soft Tissues Technique on Piriformis Syndrome Patients Myofascial Release, Post Isometric Relaxation - Piriformis Syndrome, Musculoskeletal Abnormalities | Not applicable | Not yet recruiting | University of Faisalabad | 26 | 2026-06-30 | 2026-06-30 |
| Comparing the Effectiveness of Tensioner Vs Slider Neurodynamic Techniques in Patients With Sciatica Slider Neurodynamic Technique Group, Tensioner Neurodynamic Technique Group - Sciatica, Sciatica Pain | Not applicable | Recruiting | Ibadat International University, Islamabad | 80 | 2026-06-03 | 2026-06-08 |
| Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control Study Piriformis Syndrome, Pes Planus | Active not recruiting | Kahramanmaras Sutcu Imam University | 70 | 2026-06-01 | 2026-06-29 | |
| Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care nerve block with ropivacaine, Standard medical treatment - Sciatica Acute | Not applicable | Recruiting | University of California, San Francisco | 100 | 2026-05-26 | 2026-06-02 |
| Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome Post Isometric Relaxation, Active Isolated Stretching - Piriformis Syndrome, Low Back Pain | Not applicable | Recruiting | Foundation University Islamabad | 40 | 2026-05-20 | 2026-05-20 |
| Efficacy of Sciatic Nerve Electrical Stimulation and Therapeutic Exercise in the Management of Low-back Related Leg Pain Percutaneous Electrical Nerve Stimulation, Placebo Transcutaneous Electrical Nerve Stimulation, Transcutaneous Electrical Nerve Stimulation - Sciatica | Not applicable | Recruiting | Universidad Complutense de Madrid | 88 | 2026-05-13 | 2026-05-14 |
| Immediate and 1-week Efficacy of a Single Session of Sciatic Nerve Electrical Stimulation in the Management of Low-back Related Leg Pain Percutaneous Electrical Nerve Stimulation, Placebo Transcutaneous Electrical Nerve Stimulation, Transcutaneous Electrical Nerve Stimulation - Sciatica | Not applicable | Recruiting | Universidad Complutense de Madrid | 88 | 2026-05-13 | 2026-05-14 |
| Segmental Decompression Versus Wide Decompression With Fixation for Degenerative Lumbar Canal Stenosis Segmental Decompression, Wide Decompression with Fixation - Degenerative Lumbar Spinal Stenosis | Not applicable | Not yet recruiting | Assiut University | 56 | 2026-05-01 | 2026-04-21 |
Showing 20 of 200. Sign in to see all of them.
Sciatica (143) · Piriformis Muscle Syndrome (57) · Low Back Pain (49) · Radiculopathy (38) · Intervertebral Disc Displacement (30) · Back Pain (19) · Pain (18) · Chronic Pain (8) · Motor Activity (7) · Neuralgia (6) · Agnosia (5) · Intervertebral disc disease (5) · Spinal Stenosis (4) · Complex Regional Pain Syndromes (3)
Mononeuropathies (200) · Nervous System Diseases (200) · Neuromuscular Diseases (199) · Peripheral Nervous System Diseases (199) · Pathological Conditions, Signs and Symptoms (197) · Neurologic Manifestations (196) · Signs and Symptoms (194) · Neuralgia (190) · Pain (178) · Nerve Compression Syndromes (58) · Pelvic Pain (56) · Back Pain (43) · Musculoskeletal Diseases (41) · Bone Diseases (38)
Acupuncture Therapy (8) · Electroacupuncture (7) · Muscle Stretching Exercises (5) · Dexamethasone (4) · Nerve Growth Factor (4) · Physical Therapy Modalities (4) · Phytotherapy (4) · Transcutaneous Electric Nerve Stimulation (4) · Acetaminophen (3) · Cupping Therapy (3) · Extracorporeal Shockwave Therapy (3) · Lidocaine (3) · Low-Level Light Therapy (3) · Methylprednisolone (3) · Morphine (3)
Riphah International University (20) · Foundation University Islamabad (6) · Jaseng Medical Foundation (6) · Istanbul University - Cerrahpasa (5) · University of Lahore (5) · Biogen (4) · Johns Hopkins University (4) · Cairo University (3) · Kaiser Permanente (3) · National Institute of Dental and Craniofacial Research (NIDCR) (3) · Universidad Complutense de Madrid (3) · Ankara City Hospital Bilkent (2) · Assistance Publique - Hôpitaux de Paris (2) · Ibadat International University, Islamabad (2) · Marmara University (2)
United States (46) · Pakistan (42) · Turkey (Türkiye) (23) · France (9) · Canada (8) · South Korea (8) · Australia (6) · Egypt (6) · Spain (5) · Israel (4) · Netherlands (4) · China (3) · Taiwan (3) · Belgium (2) · Denmark (2)
Steven P Cohen, MD (4) · Asghar Khan, Phd (2) · Dmitri Lissin, MD (2) · Julie M Fritz, PhD (2) · Aaron Bernstein, PhD (1) · Aiza Yousaf, MSOMPT (1) · Amnah Anum, MSPT (1) · Andrew L. Avins, MD, MPH (1) · Anne Haugen, MD,PhD (1) · Arnaud Dupeyron (1) · Aruba Saeed, Phd (1) · Asim Arif, PhD (1)
PMID 25794202, PMID 28836092, PMID 11145807, PMID 11525209, PMID 12384756, PMID 12897484, PMID 15115710, PMID 15454701, PMID 15615926, PMID 15844437, PMID 16192528, PMID 16371894, PMID 17414235, PMID 18458807, PMID 1880438, PMID 19301989, PMID 19387178, PMID 19403008, PMID 20433733, PMID 20506391, PMID 20864600, PMID 21267044, PMID 21334547, PMID 21686825, PMID 21912311, PMID 22059194, PMID 22157067, PMID 22308105, PMID 22508732, PMID 22547561, PMID 22863240, PMID 23023899, PMID 23684469, PMID 23725488, PMID 23781912, PMID 23877110, PMID 23900507, PMID 25029916, PMID 25230270, PMID 25313534, PMID 25371087, PMID 25603749, PMID 25724849, PMID 25883095, PMID 25962165, PMID 25988461, PMID 26266421, PMID 26358634, PMID 26459006, PMID 26596627
2014 (1), K12NS130673 (1), R01AR053960 (1), R34AT011209 (1)