619 unknown. 619 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 619 | Unknown 619 |
Follow Nervous System Diseases: new trials by email Literature Review of Nervous System Diseases trials Research Report on Nervous System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Dolutegravir Compared With Darunavir/Cobicistat on the Severity of Neuropsychiatric Effects al 12 Weeks in Antirretroviral Treatment-Naive Adults. Dolutegravir (DTG), Darunavir/Cobicistat (FDC) - HIV, Insomnia | Phase 4 | Unknown | Instituto Mexicano del Seguro Social | 140 | 2025-06-19 | 2025-06-26 |
| Oral Bedtime Melatonin in Critically Ill Patients Oral Bedtime Melatonin, Placebo suspension or capsule - Septic Shock, Stroke Hemorrhagic | Phase 4 | Unknown | Hospital San Carlos, Madrid | 160 | 2025-02-01 | 2024-03-01 |
| Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip Replacement Nasal spray dexmedetomidine - Delirium | Phase 4 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 264 | 2024-11-21 | 2025-01-23 |
| Low Flow Anesthesia in Children Undergoing Strabismus Surgery Sevoflurane; In our study, the effects of sevoflurane in different FGFs administered in children undergoing strabismus surgery on EA and anesthetic agent consumption will be investigated. - Low Flow Anesthesia, Sevoflurane | Phase 4 | Unknown | Cukurova University | 150 | 2024-11-04 | 2024-08-26 |
| Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia Dexamethasone, Tocilizumab, Anakinra - Sepsis, Neuroinflammatory Response | Phase 4 | Unknown | Radboud University Medical Center | 52 | 2024-10-24 | 2025-04-04 |
| Effects of Esketamine on Postoperative Behavioral Changes in Children Undergoing Tonsillectomy and/or Adenoidectomy Esketamine hydrochloride, normal saline - Behavior Problem | Phase 4 | Unknown | Fujian Provincial Hospital | 172 | 2024-09-02 | 2024-10-01 |
| Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair Pregabalin - Rotator Cuff Tears, Central Sensitisation | Phase 4 | Unknown | The Catholic University of Korea | 76 | 2024-09-01 | 2024-08-23 |
| Modified TIPS Block for Total Knee Arthroplasty General Anesthesia, TIPS block, Modified TIPS block - Knee Arthropathy, Anesthesia, Local | Phase 4 | Unknown | Alexandria University | 90 | 2024-08-01 | 2024-08-06 |
| Effect of Adding Lamotrigine to Sodium Valproate in Childhood Epilepsy: Clinicolabratory Study Sodium Valproate 500 Mg Prolonged-Release Oral Tablet, Lamotrigine, E.E.G - Epilepsy, Lamotrigine | Phase 4 | Unknown | Assiut University | 50 | 2024-07-29 | 2024-07-30 |
| Pair Antiplatelet THerapy in Ischemic Stroke With Intracranial Artery Stenosis clopidogrel for 90 days combined with aspirin for 90 days, clopidogrel for 30 days combined with aspirin for 90 days - Ischemic Stroke, Intracranial Arteriosclerosis | Phase 4 | Unknown | Sichuan Provincial People's Hospital | 1100 | 2024-07-01 | 2024-06-18 |
| Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients Oxycodone Hydrochloride, Remifentanil - Oxycodone, Analgesia | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 60 | 2024-06-01 | 2024-06-06 |
| Efficacy and Safety Studies of Oliceridine Fumarate Oliceridine Fumarate, Remifentanil - Analgesia | Phase 4 | Unknown | Chun Pan | 292 | 2024-06-01 | 2024-06-12 |
| Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM Remimazolam besylate + propofol MCT, Propofol MCT - Neurologic Disorder | Phase 4 | Unknown | Chung-Ang University Gwangmyeong Hospital | 56 | 2024-05-01 | 2024-04-24 |
| Study on the Efficacy of Alprostadil Injection in Patients With Acute Ischemic Stroke Alprostadil, Normal saline - Stroke | Phase 4 | Unknown | The First Hospital of Jilin University | 950 | 2024-04-18 | 2024-04-01 |
| Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients Alpha Lipoic Acid 600 MG Oral Capsule - Breast Cancer, Alpha Lipoic Acid | Phase 4 | Unknown | Ain Shams University | 92 | 2024-04-01 | 2024-05-09 |
| Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery fresh frozen plasma, prothrombin complex concentrate - Prostate Cancer, Spine, Open | Phase 4 | Unknown | Konkuk University Medical Center | 154 | 2024-03-01 | 2024-01-02 |
| A Clinical Research Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorders Inebilizumab - Neuromyelitis Optica Spectrum Disorders | Phase 4 | Unknown | Hansoh BioMedical R&D Company | 33 | 2024-02-25 | 2024-01-18 |
| Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients alfacalcidol, placebo, Denosumab - Sarcopenia | Phase 4 | Unknown | Yonsei University | 340 | 2024-02-13 | 2024-02-22 |
| Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery TXA, TEG6 - Arthritis Knee, Spine Fusion | Phase 4 | Unknown | Konkuk University Medical Center | 148 | 2024-02-10 | 2024-05-14 |
| Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery Bupivacain - Postoperative Pain, Mandible Fracture | Phase 4 | Unknown | University Tunis El Manar | 30 | 2024-02-06 | 2024-02-14 |
Showing 20 of 619. Sign in to see all of them.
Agnosia (54) · Stroke (46) · Ischemic Stroke (39) · Parkinson Disease (28) · Emergence Delirium (24) · Delirium (23) · Pain, Postoperative (19) · Epilepsy (18) · Migraine Disorders (18) · Alzheimer Disease (17) · Depression (14) · Multiple Sclerosis (14) · Sleep Apnea, Obstructive (14) · Brain Injuries, Traumatic (13) · Sleep Initiation and Maintenance Disorders (13)
Central Nervous System Diseases (310) · Pathological Conditions, Signs and Symptoms (286) · Brain Diseases (282) · Signs and Symptoms (230) · Neurologic Manifestations (218) · Cardiovascular Diseases (135) · Vascular Diseases (131) · Mental Disorders (121) · Neurobehavioral Manifestations (120) · Cerebrovascular Disorders (119) · Pathologic Processes (118) · Neurocognitive Disorders (67) · Neurodegenerative Diseases (57) · Perceptual Disorders (56)
Dexmedetomidine (30) · Saline Solution (27) · Sodium Chloride (22) · Propofol (20) · Midazolam (16) · Ketamine (14) · Remifentanil (12) · Sevoflurane (12) · Aspirin (11) · Acetaminophen (10) · Clopidogrel (10) · Fentanyl (9) · Bupivacaine (8) · Dexamethasone (8) · Melatonin (8)
Seoul National University Hospital (10) · Beijing Tiantan Hospital (9) · Assiut University (8) · Peking Union Medical College Hospital (6) · Second Affiliated Hospital, Zhejiang University, School of Medicine (6) · Tanta University (6) · Tehran University of Medical Sciences (6) · Changchun GeneScience Pharmaceutical Co., Ltd. (5) · Guangzhou University of Traditional Chinese Medicine (5) · Hui Bu (5) · Medical University of Vienna (5) · Ain Shams University (4) · Asan Medical Center (4) · Chinese PLA General Hospital (4) · First Affiliated Hospital Xi'an Jiaotong University (4)
China (128) · United States (67) · South Korea (37) · Canada (27) · Egypt (25) · Brazil (22) · Italy (20) · Turkey (Türkiye) (18) · United Kingdom (18) · Israel (17) · Taiwan (16) · Germany (15) · France (13) · Spain (11) · Denmark (10)
Barjesh C Sharma, MD,DM (3) · Burkhard Gustorff, MD (3) · Messoud Ashina, MD (3) · Beom S Jeon, MD, PhD (2) · Eungseok Oh (2) · Hui Bu (2) · Hung-Te Hsu, MD, PhD (2) · Jian-Xin Zhou, MD (2) · Jinse Park (2) · Jisun Kim (2) · Joost J. van Middendorp, MD, PhD (2) · Ka Wing Ma, MBBS, MS (2)
PMID 37303034, PMID 17197840, PMID 24957314, PMID 40275185, PMID 10525595, PMID 10639539, PMID 10863041, PMID 1135616, PMID 11573581, PMID 11812709, PMID 11897754, PMID 11914403, PMID 11937179, PMID 12135313, PMID 12457622, PMID 12493255, PMID 12760985, PMID 12767787, PMID 12768180, PMID 12804680, PMID 12807523, PMID 12873949, PMID 1356988, PMID 14558057, PMID 14581662, PMID 14656957, PMID 14684785, PMID 15041597, PMID 15135924, PMID 15187032, PMID 15199078, PMID 15304586, PMID 15312228, PMID 15367828, PMID 15673874, PMID 15714182, PMID 15767218, PMID 15837243, PMID 15879332, PMID 16045848, PMID 16247923, PMID 16386660, PMID 16415388, PMID 16448896, PMID 16476843, PMID 16526829, PMID 16531613, PMID 16638802, PMID 16899504, PMID 16952918
2009 (4), 2014 (3), 2005 (2), 2017 (2), 2018 (2), 2008 (1), 2015 (1), 2019 (1), 2023 (1), R01NS064905 (1), R44NS067772 (1)