435 completed, 146 unknown, 53 recruiting, 48 terminated. 299 Phase 4, 158 Phase 3, 84 Phase 2, 82 Phase 1, 67 Not applicable.
Follow Clopidogrel: new trials by email Literature Review of Clopidogrel trials Research Report on Clopidogrel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial Acetylsalicylic acid ASA, ASA plus Clopidogrel - SCAD, ACS (Acute Coronary Syndrome) | Phase 4 | Not yet recruiting | Universitätsklinikum Hamburg-Eppendorf | 3518 | 2027-03-01 | 2026-10-16 |
| A Pilot Study to Investigate Platelet Reactivity in Patients With Elevated Lipoprotein(a) and Its Response to Antiplatelet Therapy Aspirin, Clopidogrel - Cardiovascular Prevention | Not applicable | Not yet recruiting | François MACH | 60 | 2026-11-01 | 2026-07-22 |
| Short-Term Dual Antiplatelet Therapy With Early Transi-tion to Low-dose Antiplatelet Monotherapy Using Ti-cagRelor in Chronic Coronary Artery Disease Ticagrelor 60 mg, clopidogrel 75 mg - Chronic Coronary Syndrome | Phase 4 | Not yet recruiting | University of Messina | 1000 | 2026-11-01 | 2026-09-15 |
| A Clinical Trial of Antiplatelets in Psoriasis Aspirin, Clopidogrel, Placebo - Psoriasis (PsO), Psoriatic Arthritis (PsA) | Phase 4 | Not yet recruiting | NYU Langone Health | 60 | 2026-09-01 | 2026-08-05 |
| Prevalence of CYP2C19 Genetic Polymorphisms Among Egyptian Patients Receiving Clopidogrel Following PCI Clopidogrel - Acute Coronary Syndrome | Enrolling by invitation | October 6 University | 1000 | 2026-08-01 | 2026-10-21 | |
| BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis Apixaban, Clopidogrel - Stroke, Ischemic | Phase 4 | Recruiting | Yonsei University | 586 | 2026-07-14 | 2026-10-16 |
| Efficacy and Safety of Indobufen, Aspirin, Cilostazol and Clopidogrel in the Treatment of Ischemic Stroke indubufen, aspirin, clopidogrel, cilostazol - Acute Ischemic Stroke | Not yet recruiting | Nanfang Hospital, Southern Medical University | 2000 | 2026-07-01 | 2026-05-22 | |
| HR-MRI-Directed Tirofiban Therapy for Late-Window Acute Ischemic Stroke (TIAN) Tirofiban, dual antiplatelet therapy - Stroke, Acute, Stroke, Ischemic | Phase 3 | Recruiting | Weifang Medical University | 458 | 2026-06-22 | 2026-06-25 |
| Duration of Dual Anti-Platelet Therapy in Chronic Limb Threatening Ischemia After Distal Revascularization Clopidogrel 75 mg/day, Placebo Clopidogrel - CLTI Defined as Rutherford Category 4 or 5 | Phase 3 | Recruiting | Fondation Hôpital Saint-Joseph | 614 | 2026-06-12 | 2026-06-24 |
| Platelet Aggregation Function-Guided De-Escalation Antiplatelet Therapy in Patients With Acute Ischemic Stroke Clopidogrel, Aspirin - Ischemic Stroke, Transient Ischemic Attack | Phase 4 | Not yet recruiting | Sichuan Provincial People's Hospital | 3836 | 2026-06-01 | 2026-06-12 |
| Adjuvant Clopidogrel in Staphylococcus Aureus Bacteremia Clopidogrel, No antiplatelet treatment - Bacteremia Due to Staphylococcus Aureus | Phase 2 | Not yet recruiting | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 230 | 2026-06-01 | 2026-02-05 |
| The Pharmacokinetics and Pharmacodynamics Study of Evategrel CG-0255 Besylate）and Plavix® in Healthy Participants CG-0255 Besylate for Injection, CG-0255 Besylate Capsule, Clopidogrel - Acute Coronary Syndromes (ACS), Recent Myocardial Infarction | Phase 1 | Recruiting | Shanghai CureGene Pharmaceutical Co., Ltd. | 136 | 2026-06-01 | 2026-06-29 |
| Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty. Clopidogrel, Ticagrelor, Prasugrel - Coronary Artery Disease, Percutaneous Coronary Intervention | Phase 3 | Recruiting | Cardiocentro Ticino | 355 | 2026-04-20 | 2026-05-13 |
| Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial Edoxaban 15 mg, Aspirin or clopidogrel - Stroke, Ischemic | Phase 3 | Not yet recruiting | Sunnybrook Health Sciences Centre | 1204 | 2026-04-01 | 2026-03-06 |
| Aspirin 50mg vs 100mg Combined With P2Y12 Inhibitor After PCI Aspirin, P2Y12 inhibitor - Coronary Artery Disease, Acute Coronary Syndromes | Not applicable | Recruiting | Jilin University | 2640 | 2026-03-01 | 2026-10-01 |
| Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary Artery Ectasia Aspirin 100 mg, Clopidogrel 75 mg, Rivaroxaban 15 mg - Coronary Artery Ectasia, Acute Coronary Syndromes (ACS) | Phase 4 | Recruiting | Instituto Nacional de Cardiologia Ignacio Chavez | 326 | 2026-02-11 | 2026-04-09 |
| Clopidogrel vs. Aspirin for Cardiovascular Risk Reduction in Patients With S. Aureus Bacteremia Clopidogrel, Aspirin - Staphylococcus Aureus Endocarditis, Staphylococcus Aureus Septicemia | Phase 4 | Recruiting | Todd C. Lee MD MPH FIDSA | 300 | 2026-01-15 | 2026-09-24 |
| Acetyl-leucine in Post-stroke Ataxia Acetyl-Leucine, Placebo, Clopidogrel 75 Mg Oral Tablet - Ischemic Stroke | Phase 3 | Recruiting | Kafrelsheikh University | 200 | 2025-12-01 | 2025-12-10 |
| A EUROpean Randomized Study on Blood-thinners and Cholesterol-lowering Treatments to Prevent Future Vascular Events in People With Covert Brain Infarcts (CBI) acetylsalicyclic acid (ASA), Clopidogrel, Rosuvastatin - Covert Brain Infarction | Phase 3 | Recruiting | Aarhus University Hospital | 1652 | 2025-11-26 | 2025-12-04 |
| to Evaluate the Safety and the Pharmacokinetic and Pharmacodynamic Interactions Between JP-1366 and Clopidogrel, Aspirin, Atorvastatin and Apixaban JP-1366 and clopidogrel, JP-1366 and aspirin, JP-1366 and atorvastatin - Drug Drug Interaction (DDI) | Phase 1 | Recruiting | Onconic Therapeutics Inc. | 96 | 2025-11-17 | 2025-12-04 |
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Coronary Artery Disease (166) · Acute Coronary Syndrome (102) · Ischemic Stroke (61) · Myocardial Infarction (53) · Stroke (47) · Cardiovascular Diseases (34) · Coronary Disease (34) · Thrombosis (32) · Peripheral Arterial Disease (27) · Atrial Fibrillation (26) · Myocardial Ischemia (24) · ST Elevation Myocardial Infarction (23) · Atherosclerosis (18) · Hemorrhage (18) · Angina, Stable (17)
Sanofi (26) · AstraZeneca (19) · Eli Lilly and Company (14) · University of Florida (14) · Kafrelsheikh University (10) · Assistance Publique - Hôpitaux de Paris (9) · First Affiliated Hospital of Harbin Medical University (9) · Seoul National University Hospital (9) · University of Patras (9) · Beijing Tiantan Hospital (8) · Ottawa Heart Institute Research Corporation (8) · Samsung Medical Center (8) · Seung-Jung Park (8) · Yonsei University (8) · Boehringer Ingelheim (7)
United States (181) · China (117) · South Korea (100) · Canada (66) · Germany (59) · France (55) · Italy (50) · United Kingdom (46) · Spain (41) · Netherlands (39) · Brazil (30) · Belgium (28) · Poland (28) · Austria (27) · Greece (26)
Adnan Kastrati, MD (5) · Dominick J Angiolillo, MD, PhD (5) · Glenn Carlson, MD (4) · Joo-Yong Hahn, MD, PhD (4) · Julinda Mehilli, MD (4) · Moo Hyun Kim, MD (4) · Seung-Jung Park, MD, PhD (4) · Dominick J Angiolillo, MD,PhD (3) · Hyeon-Cheol Gwon, MD, PhD (3)
PMID 35224730, PMID 31867054, PMID 18190818, PMID 19717846, PMID 40875095, PMID 19923168, PMID 20844485, PMID 2375765, PMID 16731270, PMID 17261652, PMID 20194878, PMID 27902833, PMID 28382371, PMID 28988157, PMID 29632238, PMID 35196863, PMID 37489818, PMID 38551015, PMID 12807523, PMID 15738352, PMID 17418288, PMID 17982182, PMID 19106084, PMID 19324253, PMID 19336502, PMID 20079528, PMID 20231231, PMID 20432394, PMID 20531008, PMID 20650435, PMID 20681275, PMID 21079055, PMID 21545948, PMID 22007612, PMID 22019563, PMID 2203564, PMID 22212857, PMID 22305835, PMID 22795280, PMID 22837373, PMID 23303884, PMID 23517020, PMID 24065443, PMID 24677117, PMID 25173339, PMID 26089177, PMID 27160944, PMID 27480425, PMID 27847338, PMID 28527771
2014 (6), 2015 (5), 2008 (4), 2009 (3), 2023 (3), 2025 (3), U01GM074518 (2), U01HL105198 (2), 1OT2HL156812-01 (1), 1UL1RR025774-01 (1), 2016 (1), 2017 (1), 2019 (1), K23HL105897 (1), K23HL141651 (1)