46 completed, 12 unknown, 9 recruiting, 5 withdrawn. 25 Not applicable, 20 Phase 4, 16 Phase 2, 15 Phase 3, 4 Phase 1.
Follow this drug Literature Review of Vasopressins trials Research Report on Vasopressins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery, Vasopressin, Norepinephrine - Anesthesia, Pulmonary Hypertension | Phase 2 | Not yet recruiting | Fondation Hôpital Saint-Joseph | 90 | 2026-08-01 | 2026-06-02 |
| Phenotype Guided Vasoactive Medication During Kidney Transplantation Phenotype-Guided Vasoactive Management - Kidney Transplant, Fluid Management | Phase 4 | Not yet recruiting | Jennifer Cutler | 255 | 2026-06-01 | 2026-06-08 |
| Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator Vasopressin - Shock, Septic | Terminated | The Cleveland Clinic | 2 | 2025-10-01 | 2026-02-19 | |
| Early Versus Late Adjunctive Vasopressin in Septic Shock vasopressin - early initiation, vasopressin - standard initiation - Sepsis, Septic Shock | Phase 4 | Recruiting | The Cleveland Clinic | 300 | 2025-04-29 | 2026-08-31 |
| Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU Vasopressin, 0,9% saline solution - Critical Illness | Phase 2 | Recruiting | Hospital do Coracao | 60 | 2025-04-10 | 2025-04-13 |
| Norepinephrine and Vasopressin for Rescue Versus Early Vasopressin for Vasopressor Dependent Sepsis Early Vasopressin, Norepinephrine and Vasopressin for Rescue - Septic Shock | Phase 3 | Recruiting | Hospital do Coracao | 2800 | 2024-11-21 | 2026-01-30 |
| Registry of Patients in Shock Treated With Vasopressin Vasopressin - Vasopressin Causing Adverse Effects in Therapeutic Use, Shock | Unknown | Hospital Universitario 12 de Octubre | 500 | 2024-07-09 | 2024-07-15 | |
| Tranexamic Acid in Vaginal Reconstructive Surgery Tranexamic acid, Vasopressin, NaCl 0.9% - Pelvic Organ Prolapse | Phase 4 | Withdrawn | The University of Texas Medical Branch, Galveston | 2024-07-01 | 2025-01-31 | |
| CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial Calcium Gluconate, Vasopressin, saline placebo - Trauma, Hemorrhage | Phase 2 | Recruiting | Jason Sperry | 1050 | 2024-06-30 | 2026-09-29 |
| Vasopressin Versus Tranexamic Acid for Control of Blood Loss Related to Abdominal Hysterectomy Vasopressin, Tranexamic acid, Saline - Uterine Surgery | Phase 4 | Unknown | Al-Azhar University | 387 | 2024-04-01 | 2024-03-06 |
| Inotropic Effects of Vasopressin Versus Noradrenaline In Patients With Vasoplegic Syndrome After Cardiac Surgery Vasopressin intravenous infusion, Norepinephrine intravenous infusion - Vasoplegic Syndrome of Cardiac Surgery | Phase 4 | Recruiting | University of Sao Paulo | 350 | 2024-04-01 | 2025-04-30 |
| The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study Vasopressin, Placebo - Healthy | Not applicable | Unknown | University of Electronic Science and Technology of China | 80 | 2024-03-05 | 2024-04-11 |
| Oral Vasopressin Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking Study Vasopressin, Placebo - Healthy | Not applicable | Unknown | University of Electronic Science and Technology of China | 80 | 2024-03-05 | 2024-04-11 |
| Vasopressin for Septic Shock Pragmatic Trial Vasopressin, Recommendation to use a lower initiation threshold for vasopressin, Recommendation to use a higher initiation threshold for vasopressin - Septic Shock | Phase 4 | Completed | Intermountain Health Care, Inc. | 3959 | 2024-02-01 | 2026-08-03 |
| The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock Angiotensin II, Vasopressin, Norepinephrine - Septic Shock, Acute Kidney Injury | Not applicable | Recruiting | King's College Hospital NHS Trust | 45 | 2024-01-05 | 2025-04-04 |
| Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation Vasopressin, Epinephrine - Cardiac Arrest Neonatal | Phase 1 | Active not recruiting | University of Alberta | 8 | 2023-11-27 | 2026-04-09 |
| Methods Decreasing Bleeding in Open Myomectomy Misoprostol, Tourniquet, Carbetocin - Misoprostol Allergy, Oxytocin Allergy | Phase 4 | Unknown | Cairo University | 105 | 2023-03-15 | 2023-04-10 |
| Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation Vasopressin, Norepinephrine, Collection of clinical data - Scheduled Cardiac Surgery With Extracorporeal Circulation, Vasoplegic Syndrome | Phase 3 | Active not recruiting | Centre Hospitalier Universitaire Dijon | 840 | 2023-01-02 | 2025-12-22 |
| Noradrenaline Versus Glypressin for Prevention of Hypotension After Deflation of Tourniquet in Knee Arthroplasty Saline, Norepinephrine, glypressin - Norepinephrine, Glypressin, Tourniquet Deflation, Hypotension | Not applicable | Completed | Tanta University | 135 | 2022-12-01 | 2023-11-22 |
| Hypotension in the Weaning From Vasopressor Drugs Norepinephrine, Vasopressin - Septic Shock | Phase 4 | Completed | Hospital Nossa Senhora da Conceicao | 78 | 2022-05-01 | 2025-03-14 |
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Diabetes Insipidus (42) · Shock, Septic (14) · Hypotension (8) · Shock (7) · Acute Kidney Injury (5) · Heart Arrest (5) · Hemorrhage (5) · Autism Spectrum Disorder (3) · Myoma (3) · Sepsis (3) · Wounds and Injuries (3) · Autistic Disorder (2) · Blood Loss, Surgical (2) · Critical Illness (2) · Liver Cirrhosis (2)
University of Electronic Science and Technology of China (5) · Stanford University (4) · The Cleveland Clinic (3) · University of Sao Paulo (3) · Hospital do Coracao (2) · Seoul National University Hospital (2) · University of Athens (2) · Ain Shams University (1) · Al-Azhar University (1) · Asan Medical Center (1) · Ascher-Walsh, Charles, M.D. (1) · Aswan University Hospital (1) · Baylor College of Medicine (1) · Bowdoin College (1) · Brigham and Women's Hospital (1)
United States (32) · South Korea (9) · Brazil (6) · China (5) · Egypt (4) · Canada (3) · France (2) · Greece (2) · India (2) · Italy (2) · Austria (1) · Germany (1) · Jamaica (1) · Japan (1) · Netherlands (1)
Benjamin Becker, Dr (2) · Keith Kendrick, PhD (2) · Andrea Morelli, MD (1) · Anjali Ganda, M.D., M.S. (1) · Ann Tran, MD (1) · Antonio Y Hardan, MD (1) · Antonio Y. Hardan, M.D. (1) · Bruno M Tomazini, MD (1) · Carlo Manno, MD (1) · Carrie A Sims, MD, MS (1) · Cassio Mallmann, MD (1) · Chandra Ramamoorthy, MD (1) · Charis Roussos, MD, PhD (1) · Charis Roussos, Professor (1) · Charles Ascher-Walsh, MD, MPH (1)
PMID 18305265, PMID 25947955, PMID 29784057, PMID 34990764, PMID 10392549, PMID 11529214, PMID 11555538, PMID 12519925, PMID 12794416, PMID 16616623, PMID 16931974, PMID 16931995, PMID 19139319, PMID 19155900, PMID 19534818, PMID 19664253, PMID 19841897, PMID 19926252, PMID 20129334, PMID 21161222, PMID 21354681, PMID 22353644, PMID 22518026, PMID 23796235, PMID 23860985, PMID 23876539, PMID 25641242, PMID 26125087, PMID 26903338, PMID 27144689, PMID 27398737, PMID 27483065, PMID 27841822, PMID 28558702, PMID 28618919, PMID 28750598, PMID 29018407, PMID 29319721, PMID 29328496, PMID 29578250, PMID 29600824, PMID 29859008, PMID 31008870, PMID 31461138, PMID 31609774, PMID 31958982, PMID 31970567, PMID 31983763, PMID 33483132, PMID 33977793
2025 (1), R01HD091972 (1), R01MH087721 (1), R21HD078778 (1), R21MH100387 (1), UL1TR001449 (1)