121 completed, 41 unknown, 12 recruiting, 11 terminated. 78 Not applicable, 44 Phase 4, 36 Phase 2, 31 Phase 3, 20 Phase 1.
Follow Ringer's Lactate: new trials by email Literature Review of Ringer's Lactate trials Research Report on Ringer's Lactate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Amino Acid Therapy Evaluating the Incidence of New-Onset AKI Amino Acid infusion, Lactated Ringer Solution - Acute Kidney Injury | Phase 2 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 270 | 2027-10-01 | 2026-10-21 |
| A Study of hBMMSC Injection in Patients With aPAP The human Bone Marrow Mesenchymal Stem Cell (hBMMSC) injection, Lactated Ringer's Injection (crystalloid) - Autoimmune Pulmonary Alveolar Proteinosis | Phase 2 | Not yet recruiting | Jiuzhitang Maker (Beijing) Cell Technology Co.,Ltd. | 70 | 2026-10-30 | 2026-10-22 |
| Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy Amino Acid infusion, Lactated ringers solution - Acute Kidney Injury, Mechanical Ventilation | Phase 2 | Recruiting | Dana Fuhrman | 30 | 2026-07-08 | 2026-07-24 |
| Study of Protection And Repair of Endothelial-glycocalyx in Sepsis (SPARES) Fresh Frozen Plasma (blood product), MVI and lactated ringers - Sepsis | Phase 2 | Not yet recruiting | Beth Israel Deaconess Medical Center | 45 | 2026-07-01 | 2026-04-22 |
| Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells Allogeneic adipose-Derived Mesenchymal Stromal Cells, Cryostor CS10 + Ringers Lactate - Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety | Phase 1 / Phase 2 | Recruiting | Copenhagen University Hospital, Rigshospitalet | 39 | 2026-04-16 | 2026-06-09 |
| Stroke Volume-based Fluid Resuscitation in AP Lactated Ringer's, Lactated Ringers Stroke Volume Based Dosing - Acute Pancreatitis (AP) | Not applicable | Recruiting | University of Southern California | 80 | 2026-03-19 | 2026-08-10 |
| Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients Hydroxyethyl starch 130/0.4, Lactate Ringer's Solution - Transcatheter Aortic Valve Replacement, Hemodynamic Stability | Not applicable | Not yet recruiting | Air Force Military Medical University, China | 116 | 2026-02-16 | 2026-02-27 |
| Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery Lactated Ringer 500ml, Lactated Ringer 1000ml - Laparoscopic Cholecystectomy | Phase 1 | Recruiting | King Edward Medical University | 380 | 2025-12-01 | 2026-03-23 |
| Fluid Administration in Ketoacidosis (DRINK) Fluid resuscitation with isotonic saline only, Fluid resuscitation with Ringer Lactate - Diabetic Keto-acidosis | Phase 4 | Recruiting | Centre Hospitalier Universitaire de Nice | 300 | 2025-11-26 | 2026-05-26 |
| Normal Saline Versus Ringer's Lactate for Initial Fluid Resuscitation in Sepsis Ringer's Lactate, Normal Saline (0.9% Sodium Chloride) - Sepsis | Phase 4 | Not yet recruiting | Egemen Yildiz | 88 | 2025-11-01 | 2025-11-21 |
| Indometacin With or Without Aggressive Intravenous Hydration to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave Lithotripsy Indometacin suppository, Lactated ringers solution, Normal Saline - Pancreatitis, Chronic, Pancreatitis, Acute | Not applicable | Recruiting | Changhai Hospital | 1250 | 2025-10-13 | 2026-04-13 |
| Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor 5% Dextrose (D5) in Normal Saline (NS), Lactate Ringer - Induced Labor | Phase 4 | Recruiting | Eastern Virginia Medical School | 158 | 2025-09-01 | 2025-08-22 |
| Amino Acids for Cardiac Surgery Associated AKI Amino Acids, Placebo - Acute Kidney Injury | Phase 2 | Not yet recruiting | Stanford University | 30 | 2025-09-01 | 2025-06-03 |
| The Effect of Preoperative Intravenous Fluid Bolus on Post-induction Hypotension in Elective Cystoscopies. Lactated Ringers - Postinduction Hypotension, Hypotension During Surgery | Phase 4 | Enrolling by invitation | University of Missouri-Columbia | 100 | 2025-07-14 | 2025-09-18 |
| Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff - Pre-Eclampsia | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 62 | 2025-07-01 | 2024-12-06 |
| Randomized Control Study in REsuscitation of SEpsis Trial Pharmaceutical fresh frozen plasma, Normal Saline, Ringer lactate (RL) - Septic Shock, Pediatric Critical Illness | Phase 4 | Not yet recruiting | Fundación Cardioinfantil Instituto de Cardiología | 150 | 2025-07-01 | 2025-06-25 |
| Effect of Treatment of Pre-induction Hypertension on Hemodynamic Stability During Induction of General Anesthesia Clevidipine, Lactated Ringers, Intravenous - Hypertension | Phase 4 | Not yet recruiting | University of California, San Diego | 64 | 2025-01-01 | 2024-11-08 |
| Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis Imatinib, Compound sodium lactate solution - Sepsis, Fluid Overload | Phase 1 / Phase 2 | Unknown | Belfast Health and Social Care Trust | 65 | 2024-12-01 | 2024-10-04 |
| Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin - Pregnancy, Cesarean Delivery | Not applicable | Completed | Sameh Fathy | 162 | 2024-10-27 | 2025-05-21 |
| Effect of Fluid Resuscitation on Lactate in Traumatic Injury Patients 3% hypertonic Saline, Ringer's lactated solution, 0.9% Normal saline - Fluid Resuscitation | Phase 1 / Phase 2 | Unknown | Assiut University | 150 | 2024-08-01 | 2024-04-17 |
Showing 20 of 204. Sign in to see all of them.
Pancreatitis (13) · Sepsis (13) · Shock, Septic (11) · Acute Kidney Injury (10) · Hypotension (10) · Hemorrhage (9) · Critical Illness (8) · Shock (7) · Postoperative Complications (6) · Wounds and Injuries (6) · Acidosis (5) · Burns (5) · Postoperative Nausea and Vomiting (5) · Vomiting (5) · Hypovolemia (4)
Assiut University (6) · Nanjing Medical University (5) · Innogene Kalbiotech Pte. Ltd (4) · Vanderbilt University (4) · Yuria-Pharm (4) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (3) · Mahidol University (3) · McGill University Health Centre/Research Institute of the McGill University Health Centre (3) · Post Graduate Institute of Medical Education and Research, Chandigarh (3) · Sangart (3) · University of Sao Paulo (3) · Assistance Publique Hopitaux De Marseille (2) · Baxter Healthcare Corporation (2) · Changhai Hospital (2) · Children's Hospital of Philadelphia (2)
United States (56) · China (20) · Canada (12) · Egypt (11) · France (7) · Italy (7) · South Korea (6) · Denmark (5) · Indonesia (5) · Moldova (4) · Switzerland (4) · Ukraine (4) · United Kingdom (4) · Uzbekistan (4) · Austria (3)
XiaoFeng Shen, MD (5) · Xavier Leverve, MD, PhD (3) · Fran Balamuth, MD PhD MSCE (2) · George Harb, MD, MPH (2) · Pietro Caironi, MD (2) · Adam Rahman, MD, FRCPC (1) · Ahlem Trifi (1) · Ahmed M Soliman (1) · Ali Hassan (1) · Amanda B Hassinger, MD, MS (1) · Ambrose Agweyu, PhD (1) · Amy Lee, MD (1) · Andrea Cornini, MD (1) · Andrea Holzer, MD (1) · Andrea Kurz, MD (1)
PMID 28302179, PMID 29485925, PMID 33196806, PMID 35443809, PMID 10102718, PMID 11046201, PMID 11794169, PMID 12243433, PMID 14695734, PMID 15115561, PMID 15591303, PMID 16996315, PMID 17122578, PMID 18283138, PMID 18456219, PMID 18666740, PMID 19115651, PMID 20156348, PMID 20609131, PMID 20924555, PMID 21336114, PMID 21615299, PMID 21705897, PMID 22322966, PMID 23073953, PMID 23353941, PMID 23896955, PMID 23984731, PMID 24054878, PMID 24415398, PMID 24635772, PMID 24635773, PMID 24666826, PMID 24970272, PMID 25004316, PMID 25099709, PMID 25115420, PMID 25189175, PMID 25272316, PMID 25407570, PMID 25472864, PMID 25758624, PMID 25776532, PMID 25904407, PMID 26257082, PMID 26475802, PMID 26496098, PMID 26945358, PMID 27311618, PMID 27632067
2008 (2), 2014 (1), 2019 (1), 2023 (1), D43TW009345 (1), P20GM113125 (1), R01HD100540 (1), R01HD101528 (1), R01HL073233 (1)