75 completed, 23 unknown, 18 recruiting, 11 terminated. 60 Not applicable, 23 Phase 2, 15 Phase 3, 12 Phase 1, 10 Phase 4.
Follow Hypotension, Orthostatic: new trials by email Literature Review of Hypotension, Orthostatic trials Research Report on Hypotension, Orthostatic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial) Tamsulosin hydrochloride 0.2 mg, Placebo - Benign Prostatic Hyperplasia | Phase 4 | Not yet recruiting | Shanghai East Hospital | 400 | 2026-12-01 | 2026-09-29 |
| Cardiovascular Autonomic Function After Resistance Training Upper-Limb Resistance Training - Spinal Cord Injury | Not applicable | Not yet recruiting | Pusan National University Yangsan Hospital | 20 | 2026-10-01 | 2026-09-03 |
| Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury Tilt test with stimulation (real-time effects): Intervention 1, 20 sessions of stimulation (Intervention 2) - Spinal Cord Injuries, Hypotension | Not applicable | Not yet recruiting | Kessler Foundation | 10 | 2026-09-01 | 2026-06-29 |
| NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease Droxidopa Oral Product, Placebo Control - Menkes Disease | Phase 1 / Phase 2 | Recruiting | Stephen G. Kaler | 6 | 2026-08-10 | 2026-10-05 |
| Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE) Wearable holter monitor - Orthostatic Hypotension, Reflex Syncope | Recruiting | Boston Scientific Corporation | 40 | 2026-08-06 | 2026-10-14 | |
| State of Knowledge Among Nurses Regarding the Screening for Orthostatic Hypotension in Elderly Individuals in Acute Geriatric Medicine and Medical and Rehabilitation Services Administration of questionnaires on nurses' knowledge of orthostatic hypotension, its measurement, diagnosis and management - Orthostatic Hypotension | Not yet recruiting | Hôpital NOVO | 30 | 2026-07-01 | 2026-07-31 | |
| Orthostatic And Postprandial Hypotension In Hospitalized Older Adults (HOPE65) Orthostatic Hypotension, Postprandial Hypotension | Not yet recruiting | University Medical Centre Ljubljana | 500 | 2026-04-01 | 2026-03-20 | |
| Research, Development, and Application of Intelligent Diagnostic System for Orthostatic Hypotension Intelligent diagnostic system for orthostatic hypotension - Orthostatic Hypotension | Not yet recruiting | Xuanwu Hospital, Beijing | 2000 | 2026-03-01 | 2026-01-07 | |
| Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals Hypertension, Autonomic Dysfunction | Recruiting | University Medical Centre Ljubljana | 120 | 2025-10-15 | 2026-03-19 | |
| Deciphering the Mechanisms of Central BP Regulation in Patients With PD Associated With Orthostatic Hypotension Lower body negative pressure - Parkinson Disease, Orthostatic Hypotension | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 130 | 2025-10-01 | 2025-08-24 | |
| Effects of Breathing Retraining Exercises in Pregnant Females With Postural Orthostatic Tachycardia Syndrome. diaphragmatic breathing exercise, educational retraining - Orthostatic Hypotension, Heart Rate | Not applicable | Recruiting | Riphah International University | 44 | 2025-08-31 | 2026-05-11 |
| Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease ARC-IM Investigational System - Hypotension Symptomatic, Parkinson's Disease | Not applicable | Recruiting | Ecole Polytechnique Fédérale de Lausanne | 5 | 2025-07-03 | 2026-07-07 |
| Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury spinal cord transcutaneous stimulation, Ice testing - Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic | Not applicable | Recruiting | Kessler Foundation | 15 | 2025-04-01 | 2026-07-01 |
| Evaluation of the Contribution of Lower Limb and/or Abdominal Compression on Orthostatic Hypotension the supine/standing postural change test - Orthostatic Hypotension | Not applicable | Completed | Gérond'if | 43 | 2025-02-14 | 2026-04-03 |
| The Value of Near-infrared Spectroscopy and Blood Pressure Measurements in Estimating Future Fall Risk in Older Adults Falls, Orthostatic Hypotension | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 141 | 2024-12-04 | 2024-12-19 | |
| POLish Registry of CArdioneuroablation and CArdioneuromodulation cardioneuroablation, SN sparing hybrid ablation, Cardiac sympathetic denervation - Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS | Recruiting | SABAMED Medical Center Ltd. | 1000 | 2024-11-21 | 2025-09-29 | |
| Cardiopulmonary Changes Following Spinal Cord Stimulation in Individuals With Spinal Cord Injury Transcutaneous Spinal Cord Stimulation (tSCS) - Spinal Cord Injuries, Cardiovascular Diseases | Not applicable | Not yet recruiting | University of British Columbia | 22 | 2024-08-01 | 2024-04-23 |
| SalT Supplementation in Older Adults With Orthostatic Intolerance Disorders Salt supplementation (encapsulated sodium chloride) - Orthostatic Hypotension | Phase 2 | Active not recruiting | University of Galway | 42 | 2024-07-09 | 2026-06-22 |
| Frequency of Orthostatic Hypotension in Patients Who Underwent Colonoscopy Orthostatic Hypotension | Unknown | Ankara University | 150 | 2024-05-01 | 2025-01-29 | |
| The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients Comprehensive rehabilitation training, Rise-bed Training - Orthostatic Hypotension | Not applicable | Unknown | Copka Sonpashan | 80 | 2024-04-01 | 2024-03-25 |
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Spinal Cord Injuries (30) · Pure Autonomic Failure (21) · Parkinson Disease (20) · Multiple System Atrophy (18) · Hypotension (17) · Orthostatic Intolerance (11) · Syncope (9) · Autonomic Nervous System Diseases (8) · Dizziness (8) · Primary Dysautonomias (8) · Autonomic Dysreflexia (6) · Hypertension (6) · Syncope, Vasovagal (6) · Cardiovascular Diseases (5)
Vascular Diseases (148) · Nervous System Diseases (146) · Cardiovascular Diseases (144) · Autonomic Nervous System Diseases (141) · Primary Dysautonomias (141) · Orthostatic Intolerance (138) · Hypotension (132) · Central Nervous System Diseases (65) · Brain Diseases (42) · Pathological Conditions, Signs and Symptoms (40) · Basal Ganglia Diseases (36) · Movement Disorders (36) · Neurodegenerative Diseases (36) · Signs and Symptoms (34) · Wounds and Injuries (34)
Midodrine (17) · Droxidopa (14) · Pyridostigmine Bromide (4) · Atomoxetine Hydrochloride (3) · Physical Therapy Modalities (3) · Tilt-Table Test (3) · Yohimbine (3) · ampreloxetine (3) · Insulin (2) · NG-Nitroarginine Methyl Ester (2) · Standing Position (2) · Sugars (2) · 3,4-dihydroxyphenylserine aldolase (1) · Acarbose (1) · Acetazolamide (1)
Vanderbilt University Medical Center (9) · James J. Peters Veterans Affairs Medical Center (8) · Chelsea Therapeutics (5) · University of British Columbia (5) · VA Office of Research and Development (5) · Vanderbilt University (5) · Kessler Foundation (4) · Shire (4) · Hvidovre University Hospital (3) · Mayo Clinic (3) · Theravance Biopharma (3) · Beth Israel Deaconess Medical Center (2) · Boston Scientific Corporation (2) · Copenhagen University Hospital, Hvidovre (2) · Istituto Auxologico Italiano (2)
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Italo Biaggioni, MD (10) · Jill Wecht, EdD (4) · Satish R Raj, MD MSCI (3) · Gail F Forrest, PhD (2) · Horacio Kaufmann, MD (2) · Jill M Wecht, Ed.D (2) · Jill M Wecht, EdD (2) · Luis E Okamoto, MD (2) · Roy Freeman, MD (2) · William Bauman, MD (2) · Aaron Phillips, PhD (1) · Alberto Vasquez, MD (1)
PMID 21762873, PMID 27538531, PMID 28494751, PMID 33739123, PMID 10662747, PMID 11904109, PMID 11927799, PMID 12119802, PMID 12832331, PMID 12885750, PMID 15066944, PMID 15666063, PMID 15710782, PMID 15738343, PMID 17384373, PMID 17385265, PMID 17515447, PMID 17515448, PMID 17965289, PMID 18850311, PMID 19651280, PMID 20801263, PMID 20837887, PMID 21420883, PMID 22311903, PMID 23700789, PMID 23774314, PMID 23845791, PMID 24326693, PMID 25350981, PMID 26026216, PMID 26492477, PMID 26953217, PMID 27271310, PMID 27372462, PMID 27778639, PMID 28327122, PMID 29223724, PMID 30003579, PMID 30363894, PMID 31107279, PMID 31334462, PMID 32145658, PMID 32203065, PMID 32307533, PMID 33177997, PMID 33462120, PMID 33782836, PMID 33934709, PMID 34000076
R01HL144568 (2), U54NS065736 (2), 2018 (1), 2019 (1), I21RX004373 (1), IK1RX003706 (1), K23HD102663 (1), P01HL056693 (1), P01NS044233 (1), R01AG059613 (1), R01HL071784 (1), R01HL161095 (1)