18 completed, 6 terminated, 4 unknown, 2 recruiting. 31 Phase 2, 6 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 31 | Completed 18, Terminated 6, Unknown 4, Recruiting 2, Withdrawn 1 |
| Phase 1 | 6 | Completed 4, Terminated 1, Unknown 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Terminated 1 |
Follow Cardiac Arrest: new trials by email Literature Review of Cardiac Arrest trials Research Report on Cardiac Arrest
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hypertonic Lactate After Cardiac Arrest Sodium Lactate Solution - Cardiac Arrest, Ischemia Reperfusion Injury | Phase 2 | Recruiting | Erasme University Hospital | 125 | 2025-02-19 | 2025-02-21 |
| Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock. Vitamin C (Laroscorbine) + Vitamin B1 (Bevitine), standard treatment - Cardiac Arrest | Phase 2 | Terminated | Centre Hospitalier de Bethune | 65 | 2023-12-27 | 2026-10-27 |
| Inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA) inhaled nitric oxide (iNO), Sham - Cardiac Arrest | Phase 2 | Unknown | The Hospital for Sick Children | 40 | 2022-08-31 | 2023-11-30 |
| Surviving PEA in Roanoke (SPEAR) Study High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy - Cardiac Arrest, Pulseless Electrical Activity | Phase 2 / Phase 3 | Recruiting | Carol Bernier | 342 | 2022-02-16 | 2022-03-17 |
| Beta-blockade With Landiolol in Out-of-hospital Cardiac Arrest Landiolol, Sodium Chloride (NaCl) 0.9% - Cardiac Arrest | Phase 1 / Phase 2 | Unknown | Medical University of Vienna | 32 | 2021-03-03 | 2023-03-17 |
| Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest Methylprednisolone, Isotonic saline - Out-Of-Hospital Cardiac Arrest, Cardiac Arrest | Phase 2 | Completed | Christian Hassager | 158 | 2020-10-10 | 2023-03-29 |
| Vitamin C in Post-cardiac Arrest Vitamin C, Thiamine, Placebos - Cardiac Arrest | Phase 2 | Completed | Amsterdam UMC, location VUmc | 270 | 2019-10-07 | 2025-03-10 |
| Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate Cerebral oximetry (near infrared) based CPR-Algorithm - Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation | Phase 2 | Unknown | Dr. Serge Thal | 360 | 2019-07-01 | 2023-03-31 |
| Antioxidant and NMDA Receptor Blocker Wins Anoxic Brain Damage of KorEa OHCA Patients Neu2000KWL High-dose group, Neu2000KWL Low-dose group, Placebo - Cardiac Arrest | Phase 2 | Unknown | GNT Pharma | 150 | 2018-11-29 | 2019-03-06 |
| Thiamine as a Metabolic Resuscitator After Cardiac Arrest Thiamine 500 mg IV, Placebo - Cardiac Arrest | Phase 2 | Terminated | Michael Donnino | 93 | 2018-05-06 | 2023-08-24 |
| Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest Thiamine, placebo - Cardiac Arrest, Shock | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 41 | 2017-05-01 | 2025-04-10 |
| Selenium to Improve Neurological Outcome After Cardiac Arrest Sodium-selenite, Placebo - Cardiac Arrest | Phase 2 | Withdrawn | Medical University of Graz | 2017-01-01 | 2017-12-13 | |
| TIBOHCA: Safety, Tolerability and Pharmacokinetics of 2-Iminobiotin (2-IB) After OHCA 2-Iminobiotin - Cardiac Arrest, Hypoxic Ischemic Brain Injury | Phase 1 / Phase 2 | Terminated | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 21 | 2016-05-01 | 2021-02-18 |
| Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest Ubiquinol, Ensure - Cardiac Arrest | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 48 | 2016-03-01 | 2021-02-15 |
| Endothelial Dysfunction in Resuscitated Cardiac Arrest Iloprost, Saline, Phillips M1006B, offset by -10mmHg - Cardiac Arrest | Phase 2 | Completed | Pär Johansson | 50 | 2016-02-01 | 2021-03-10 |
| Bicarbonate in Patients With Out-of-hospital Cardiac Arrest Sodium bicarbonate, Normal saline - Cardiac Arrest, Metabolic Acidosis | Phase 2 | Completed | Asan Medical Center | 50 | 2014-10-01 | 2022-03-25 |
| Neuromuscular Blockade for Post-Cardiac Arrest Care Rocuronium, Normal Saline - Cardiac Arrest | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 83 | 2014-10-01 | 2021-01-29 |
| Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest Standard Care, Low Volume Hemofiltration, High Volume Hemofiltration - Cardiac Arrest | Phase 1 / Phase 2 | Completed | University of Washington | 2 | 2012-01-01 | 2016-06-09 |
| Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation Coenzyme Q10, Placebo - Cardiac Arrest, Sudden Cardiac Arrest | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 10 | 2011-02-01 | 2017-07-31 |
| Cardiopulmonary Resuscitation (CPR) Dissemination Study Using Nurses and Volunteers CPR Training using the Family and Friends CPR Anytime VSI Kit, Implementation of an In-Hospital CPR Training Model - Cardiovascular Risk Factors, Coronary Disease | Phase 1 / Phase 2 | Completed | University of Pennsylvania | 500 | 2010-10-01 | 2018-11-01 |
Showing 20 of 31. Sign in to see all of them.
Heart Arrest (31) · Death, Sudden, Cardiac (2) · Hypoxia-Ischemia, Brain (2) · Out-of-Hospital Cardiac Arrest (2) · Post-Cardiac Arrest Syndrome (2) · Shock (2) · Ventricular Fibrillation (2) · Acidosis (1) · Acidosis, Lactic (1) · Beriberi (1) · Bradycardia (1) · Brain Injuries (1) · Coronary Disease (1) · Hypothermia (1) · Inflammation (1)
Cardiovascular Diseases (31) · Heart Diseases (31) · Pathological Conditions, Signs and Symptoms (12) · Pathologic Processes (10) · Brain Diseases (5) · Central Nervous System Diseases (5) · Nervous System Diseases (5) · Vascular Diseases (5) · Arrhythmias, Cardiac (3) · Postoperative Complications (3) · Signs and Symptoms (3) · Acid-Base Imbalance (2) · Brain Injuries (2) · Brain Ischemia (2) · Cerebrovascular Disorders (2)
Saline Solution (5) · Sodium Chloride (4) · Thiamine (4) · Ascorbic Acid (2) · Epinephrine (2) · coenzyme Q10 (2) · 2-iminobiotin (1) · Aminophylline (1) · Amiodarone (1) · Atropine (1) · Defibrillators (1) · Diet, Sodium-Restricted (1) · Endothelium-Dependent Relaxing Factors (1) · Hydrocortisone (1) · Hypothermia, Induced (1)
Beth Israel Deaconess Medical Center (5) · The Hospital for Sick Children (2) · University of Oslo (2) · University of Washington (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Amsterdam UMC, location VUmc (1) · Asan Medical Center (1) · Carol Bernier (1) · Centre Hospitalier de Bethune (1) · Christian Hassager (1) · David Haines, MD (1) · Dr. Serge Thal (1) · Erasme University Hospital (1) · GNT Pharma (1) · Medical University of Graz (1)
United States (13) · Canada (3) · Norway (3) · Austria (2) · Denmark (2) · Netherlands (2) · United Kingdom (2) · Belgium (1) · France (1) · Germany (1) · New Zealand (1) · South Korea (1) · Sweden (1)
Michael W Donnino, MD (4) · Jamie Hutchison, MD (2) · Angelique ME Spoelstra-de Man, Dr. (1) · Benjamin S Abella, MD, MPhil (1) · Carol Bernier, DO (1) · Chistian Hassager, MD, DMSc (1) · Christian Hassager, MD, DMSc (1) · David E Haines, MD (1) · Elizabeth Dorph (1) · Ericka L Fink, MD (1) · Filippo Annoni, MD (1) · Francis Kim, MD (1) · Graham Nichol, MD (1) · Janneke Horn, MD, PhD (1) · Jin-Ho Choi, MD (1)
PMID 17241734, PMID 15657322, PMID 15657323, PMID 16698410, PMID 17070980, PMID 18504334, PMID 19854555, PMID 19934423, PMID 27038920, PMID 27484224, PMID 29850134, PMID 31710844, PMID 31945586, PMID 32653571, PMID 32851921, PMID 34271122, PMID 34407846, PMID 35871083, PMID 36414975, PMID 37943300, PMID 38254130, PMID 39094677, PMID 39317492, PMID 39899673, PMID 42301311
2018 (1), K23HL128814 (1), K23NS065132 (1), R01HL136705 (1)