7 completed, 1 terminated, 1 unknown. 2 Phase 1, 2 Phase 2, 2 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 4 | 2 | Completed 2 |
Follow Beriberi: new trials by email Literature Review of Beriberi trials Research Report on Beriberi
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans Thiamine repletion - Thiamine Deficiency, Thiamine Deficiency; Sequelae | Completed | VA Office of Research and Development | 206 | 2022-07-19 | 2026-08-12 | |
| Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs Thiamine Mononitrate - Heart Diseases | Phase 3 | Unknown | Mahidol University | 60 | 2019-07-01 | 2019-06-20 |
| The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine Trimethoprim, Metformin, Vitamin B1 - Vitamin B1 Deficiency, Thiamine Deficiency | Phase 4 | Completed | University of California, San Francisco | 7 | 2019-01-28 | 2025-01-03 |
| Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest Thiamine, placebo - Cardiac Arrest, Shock | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 41 | 2017-05-01 | 2025-04-10 |
| Alcohol: Thiamine and or Magnesium 1 Magnesium Sulfate, Pabrinex - Alcohol Withdrawal, Lactic Acidosis | Phase 2 / Phase 3 | Completed | Glasgow Royal Infirmary | 127 | 2016-12-16 | 2019-07-31 |
| Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia Thiamin fortified fish sauce (low concentration), Thiamin fortified fish sauce (higher concentration), Placebo fish sauce - Thiamin Deficiency | Phase 1 | Completed | University of British Columbia | 366 | 2014-10-01 | 2016-05-25 |
| Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants thiamine hydrochloride 100 mg - Beriberi | Phase 1 | Completed | Mayo Clinic | 24 | 2012-01-01 | 2013-05-29 |
| A Trial of Thiamin Supplementation in Patients With Heart Failure Vitamin B1, Placebo - Heart Failure | Phase 4 | Completed | Unity Health Toronto | 70 | 2009-09-01 | 2018-02-27 |
| The Prevalence of Thiamin Deficiency in Ambulatory Patients With Heart Failure Heart Failure | Completed | Unity Health Toronto | 110 | 2009-05-01 | 2012-12-24 |
Thiamine Deficiency (3) · Acidosis, Lactic (2) · Heart Failure (2) · Wernicke Encephalopathy (2) · Breast Feeding (1) · Delirium (1) · Heart Arrest (1) · Heart Diseases (1) · Magnesium Deficiency (1) · Polyneuropathies (1) · Shock (1)
Avitaminosis (9) · Deficiency Diseases (9) · Malnutrition (9) · Nutrition Disorders (9) · Nutritional and Metabolic Diseases (9) · Vitamin B Deficiency (9) · Thiamine Deficiency (6) · Cardiovascular Diseases (4) · Heart Diseases (3) · Metabolic Diseases (3) · Acid-Base Imbalance (2) · Acidosis (2) · Alcohol-Related Disorders (2) · Brain Diseases (2) · Brain Diseases, Metabolic (2)
Thiamine (4) · Magnesium Sulfate (1) · Metformin (1) · Saline Solution (1) · Thymidine Monophosphate (1) · Trimethoprim (1) · thiamine hydrochloride (1)
Unity Health Toronto (2) · Beth Israel Deaconess Medical Center (1) · Glasgow Royal Infirmary (1) · Mahidol University (1) · Mayo Clinic (1) · University of British Columbia (1) · University of California, San Francisco (1) · VA Office of Research and Development (1)
United States (4) · Cambodia (2) · Canada (2) · Thailand (1) · United Kingdom (1)
Abdul Al-Hesayen, MD (1) · Andrew S Greenberg (1) · Andrew Yan, MD (1) · Donogh Maguire, MB BCh (1) · Elisabeth A Mates, MD PhD (1) · Judy McLean, PhD (1) · Katherine M Berg, MD (1) · Kathleen M Giacomini (1) · Kyly C Whitfield, MSc (1) · Mark Topazian, M.D. (1) · Mary E. Keith, PhD, RD (1) · Mary Keith, PhD, RD (1) · Narumon Densupsoontorn, MD (1) · Tim J Green, PhD (1) · Zaman Talukder, MPH (1)
PMID 23864540, PMID 27532780, PMID 27939124, PMID 31504093, PMID 35484175, PMID 41872295
K23HL128814 (1), R01DK108722 (1)