3403 completed, 1224 unknown, 525 recruiting, 316 terminated. 2108 Not applicable, 801 Phase 4, 472 Phase 3, 392 Phase 2, 148 Phase 1.
Follow this condition Literature Review of Coronary Disease trials Research Report on Coronary Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart Disease Human Recombinant Fibroblast Growth Factor-1 (FGF 1-141) - low dose, Human Recombinant Fibroblast Growth Factor-1 (FGF1-141) - high dose, Placebo - Coronary Disease, Coronary Heart Disease | Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 150 | 2027-09-01 | 2026-08-19 |
| Rapid Engagement for Solutions to Population and Outcomes Through Networked Dialogue for Coronary Heart Disease Polygenic risk score - Coronary Heart Disease | Not yet recruiting | Medical College of Wisconsin | 200 | 2027-06-01 | 2026-05-04 | |
| Heart tEam Decision-making Assisted by Revaz AI Trial Revaz AI - Coronary Artery Disease | Not applicable | Not yet recruiting | University of Calgary | 712 | 2027-04-01 | 2026-09-24 |
| OPTIA-AF Trial: Rhythm-Guided Antithrombotic Strategy After AF Ablation Oral anticoagulation, Single antiplatelet therapy - Atrial Fibrillation (AF), Coronary Artery Disease | Phase 4 | Not yet recruiting | Ewha Womans University Mokdong Hospital | 2 | 2027-03-01 | 2026-03-27 |
| A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical Atheroma Evolocumab, Routine Lipid Management, Autoinjector - Coronary Artery Disease, Hypercholesterolemia | Phase 4 | Not yet recruiting | Amgen | 308 | 2027-01-31 | 2026-09-21 |
| Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease RespirAct - Coronary Artery Disease | Not applicable | Not yet recruiting | Indiana University | 30 | 2027-01-10 | 2026-05-26 |
| Nursing Intervention for Adaptation After Myocardial Revascularization Nursing Intervention Program, Usual Care - Coronary Artery Disease, Myocardial Revascularization | Not applicable | Not yet recruiting | Universidad de la Sabana | 40 | 2027-01-01 | 2026-05-08 |
| Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting. Photobiomodulation Therapy, Sham Laser irradiation, Conventional Saphenous Vein Harvesting - Coronary Artery Disease, Coronary Artery Bypass Graft (CABG) | Not applicable | Not yet recruiting | Federal University of São Paulo | 292 | 2027-01-01 | 2026-10-07 |
| Intraoperative Ultrasound Assessment of Coronary Artery and Bypass Graft Blood Flow During CABG Intraoperative Ultrasound Blood Flow Measurement - Coronary Artery Disease | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 190 | 2027-01-01 | 2026-08-11 | |
| wCAR-Austria: A Women-Specific Score to Assess Cardiovascular Risk in Women Aged 40 to 65 Arm 1: wCAR-CARE - Precision Prevention (Arm A), Guideline-directed standard of care - Cardiovascular Diseases (CVD), Coronary Artery Disease | Not applicable | Not yet recruiting | Women's Heart Austria | 800 | 2027-01-01 | 2026-09-30 |
| Modified Jailed Balloon Technique vs Jailed Wire Technique in Coronary Bifurcation Intervention jailed wire technique, Modified jailed balloon technique - Coronary Artery Disease | Not applicable | Not yet recruiting | Assiut University | 140 | 2027-01-01 | 2026-10-14 |
| Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation Prolonged inflation, Rapid inflation - Coronary Artery Disease, Coronary Stent Occlusion | Not applicable | Not yet recruiting | Central Arkansas Veterans Healthcare System | 40 | 2027-01-01 | 2026-10-21 |
| Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma Statins (atorvastatin, rosuvastatin, simvastatin, or pravastatin), +/- ezetimibe, +/- PCSK9 inhibitor (alirocumab, evolocumab, inclisiran) - Melanoma | Not applicable | Recruiting | University of Colorado, Denver | 40 | 2026-12-31 | 2026-08-07 |
| PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF Percutaneous coronary intervention, Guideline-directed medical therapy - Heart Failure With Reduced Ejection Fraction, Coronary Artery Disease | Not applicable | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 1154 | 2026-12-30 | 2026-05-28 |
| PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2 Initial Invasive Strategy, Initial Conservative Strategy - Coronary Artery Disease | Not applicable | Not yet recruiting | Duk-Woo Park, MD | 2500 | 2026-12-30 | 2026-10-21 |
| Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study Biomarker testing - Peri-procedural Myocardial Infarction, Heart Failure Hospitalization | Not yet recruiting | Baim Institute for Clinical Research | 1000 | 2026-12-01 | 2026-09-30 | |
| PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease | Not yet recruiting | Medical College of Wisconsin | 60 | 2026-12-01 | 2025-10-14 | |
| International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial Guideline-directed medical therapy (GDMT), Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI). - Coronary Artery Disease, Cognitive Impairment | Phase 3 | Suspended | NYU Langone Health | 1200 | 2026-12-01 | 2026-06-05 |
| Coronary Laser Atherectomy System for Treatment of Coronary Artery Stenosis (SHINE) Coronary Laser Atherectomy System, CVX300 Laser System - Coronary Artery Stenosis | Not applicable | Not yet recruiting | Shanghai MicroPort Rhythm MedTech Co., Ltd. | 218 | 2026-11-10 | 2026-08-07 |
| Efficacy and Safety of the Angionix Balloon in Patients With Coronary Artery Disease Undergoing PTCA Angionix Balloon - Coronary Artery Disease | Not yet recruiting | Yonsei University | 600 | 2026-11-09 | 2026-10-09 |
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Coronary Artery Disease (4728) · Cardiovascular Diseases (700) · Heart Diseases (501) · Myocardial Ischemia (490) · Myocardial Infarction (453) · Atherosclerosis (358) · Coronary Stenosis (314) · Diabetes Mellitus (291) · Acute Coronary Syndrome (279) · Angina Pectoris (233) · Heart Failure (220) · Hypertension (184) · Stroke (165) · Diabetes Mellitus, Type 2 (159)
Vascular Diseases (6061) · Myocardial Ischemia (5667) · Heart Diseases (5656) · Cardiovascular Diseases (5457) · Arterial Occlusive Diseases (4766) · Arteriosclerosis (4757) · Pathological Conditions, Signs and Symptoms (1533) · Pathologic Processes (1082) · Nutritional and Metabolic Diseases (656) · Signs and Symptoms (634) · Metabolic Diseases (621) · Necrosis (558) · Infarction (550) · Ischemia (542)
Clopidogrel (195) · Percutaneous Coronary Intervention (184) · Aspirin (147) · Ticagrelor (107) · Atorvastatin (77) · Coronary Artery Bypass (62) · Prasugrel Hydrochloride (61) · Exercise (57) · Rosuvastatin Calcium (56) · Drug-Eluting Stents (54) · Ezetimibe (46) · regadenoson (35) · Stents (34) · Simvastatin (33) · Tomography, Optical Coherence (33)
National Heart, Lung, and Blood Institute (NHLBI) (219) · Abbott Medical Devices (82) · China National Center for Cardiovascular Diseases (76) · Seung-Jung Park (66) · Yonsei University (66) · Seoul National University Hospital (52) · Boston Scientific Corporation (51) · Ottawa Heart Institute Research Corporation (47) · Cordis US Corp. (46) · University of Florida (42) · Deutsches Herzzentrum Muenchen (40) · Beijing Anzhen Hospital (38) · Insel Gruppe AG, University Hospital Bern (36) · Fundación EPIC (35) · Medtronic Vascular (34)
United States (1303) · China (720) · Germany (478) · South Korea (399) · United Kingdom (362) · Italy (345) · Canada (341) · Netherlands (318) · France (272) · Spain (249) · Denmark (215) · Belgium (211) · Switzerland (202) · Brazil (181) · Poland (173)
Seung-Jung Park, MD, PhD (31) · Adnan Kastrati, MD (23) · Bon-Kwon Koo, MD, PhD (20) · Shigeru Saito, MD (13) · Ron Waksman, MD (12) · Antonio Colombo, MD (11) · Gregg W Stone, MD (11) · Dominick J Angiolillo, MD, PhD (10) · Emmanouil S Brilakis, MD, PhD (10) · Shao-Liang Chen, MD (10) · David Kandzari, MD (9)
PMID 35224730, PMID 40875095, PMID 25940520, PMID 24746650, PMID 19463432, PMID 19737719, PMID 20142198, PMID 23468513, PMID 23523454, PMID 23636237, PMID 29098321, PMID 40590244, PMID 17296825, PMID 17982182, PMID 18307999, PMID 18765162, PMID 18783301, PMID 19228612, PMID 19717846, PMID 20129555, PMID 21670242, PMID 23232250, PMID 24510638, PMID 26354543, PMID 26823484, PMID 26825231, PMID 29089314, PMID 30165437, PMID 31561250, PMID 32227755, PMID 32890442, PMID 33939604, PMID 34056911, PMID 34270325, PMID 34741536, PMID 35641327, PMID 37256598, PMID 37619976, PMID 37745109, PMID 41913985, PMID 15893169, PMID 17145250, PMID 17666313, PMID 18082503, PMID 19923168, PMID 20024643, PMID 20136164, PMID 20573750, PMID 21232717, PMID 22017936
2023 (9), 2017 (7), 2018 (7), 2025 (6), 2016 (5), 2019 (5), 2014 (4), U01HL088942 (4), 2008 (3), 2015 (3), R01AG031750 (3), R01HL092954 (3), 2005 (2), 2009 (2), K23HL105897 (2)