12 completed, 3 recruiting, 2 terminated, 1 unknown. 18 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 18 | Completed 12, Recruiting 3, Terminated 2, Unknown 1 |
| Phase 2 | 3 | Completed 1, Recruiting 1, Terminated 1 |
Follow Cardiac Arrest: new trials by email Literature Review of Cardiac Arrest trials Research Report on Cardiac Arrest
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Amiodarone in Shockable Cardiac Arrest Amiodarone Hydrochloride Injection, Usual Care Protocol - Cardiac Arrest | Phase 3 | Recruiting | Oregon Health and Science University | 585 | 2025-01-01 | 2025-12-19 |
| The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients Phosphocreatine, Placebo - Hypotension, Consciousness, Level Altered | Phase 3 | Recruiting | Università Vita-Salute San Raffaele | 400 | 2024-10-08 | 2025-08-06 |
| Surviving PEA in Roanoke (SPEAR) Study High Calcium, Low Sodium (HCLS) Crystalloid Therapy, High Calcium, High Sodium (HCHS) Crystalloid Therapy - Cardiac Arrest, Pulseless Electrical Activity | Phase 2 / Phase 3 | Recruiting | Carol Bernier | 342 | 2022-02-16 | 2022-03-17 |
| Prophylactic Amiodarone for Shockable Cardiac Arrest Amiodarone Injection - Cardiac Arrest, Ventricular Arrythmia | Phase 3 | Unknown | Won Young Kim | 302 | 2021-04-01 | 2021-06-21 |
| NSE Ancillary Study of The Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial. NSE dosage "hypothermia arm", NSE dosage "normothermia arm" - Cardiac Arrest, Hypothermia | Phase 3 | Completed | Centre Hospitalier Departemental Vendee | 106 | 2016-03-01 | 2019-02-25 |
| IL Ancillary Study of the Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial. Inflammatory biomarkers dosage "Hypothermia Arm", Inflammatory biomarkers dosage "Normothermia Arm" - Cardiac Arrest | Phase 3 | Completed | Centre Hospitalier Departemental Vendee | 116 | 2016-03-01 | 2019-02-25 |
| Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia amiodarone, Lidocaine, Normal saline - Cardiac Arrest | Phase 3 | Completed | University of Washington | 3024 | 2012-05-01 | 2017-04-17 |
| Effects of Laryngeal Tube Ventilation on no Flow Time During Out of Hospital Cardiac Arrest laryngeal tube ventilation and continuous chest compression - Cardiac Arrest | Phase 3 | Completed | University Hospital, Grenoble | 84 | 2011-03-01 | 2012-07-03 |
| Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial Therapeutic Hypothermia, Therapeutic Normothermia - Cardiac Arrest | Phase 3 | Completed | University of Michigan | 295 | 2009-09-01 | 2017-09-29 |
| Hemodynamic Efficiency of an Hemodialysis Treatment With High Permeability in Post-resuscitation Shock hemodialysis with high permeability (HDHP), CVVH - Cardiac Arrest, Sudden Cardiac Death | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 38 | 2008-11-02 | 2025-09-08 |
| Vasopressin, Epinephrine, and Steroids for Cardiac Arrest Vasopressin, Epinephrine, Methylprednisolone, Hydrocortisone, Standard CPR Protocol with Epinephrine and two Placebos - Cardiac Arrest | Phase 3 | Completed | University of Athens | 300 | 2008-09-01 | 2016-11-21 |
| Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest Adrenaline, Vasopressin - Cardiac Arrest | Phase 3 | Completed | Singapore General Hospital | 727 | 2006-03-01 | 2017-03-17 |
| Fluid Shifts in Patients Treated With Therapeutic Hypothermia After Cardiac Arrest HyperHAES vs. RA-solution/NaCl - Cardiac Arrest | Phase 3 | Completed | Haukeland University Hospital | 23 | 2005-09-01 | 2009-05-01 |
| Induction of Mild Hypothermia in Resuscitated Cardiac Arrest Patients mild hypothermia - Cardiac Arrest | Phase 2 / Phase 3 | Completed | Medivance, Inc. | 64 | 2004-11-01 | 2007-09-11 |
| AutoPulse Assisted Prehospital International Resuscitation Trial (ASPIRE) AutoPulse, Manual CPR - Cardiac Arrest | Phase 3 | Terminated | University of Washington | 1837 | 2004-06-01 | 2011-01-27 |
| Effect of Early High-dose Epoetin Alfa During Cardiac Arrest (Pilot Study) Epo-alpha - Resuscitation, Cardiopulmonary | Phase 3 | Completed | Janssen Cilag S.A.S. | 20 | 2003-11-01 | 2011-05-17 |
| Assessing CPR Quality During In-Hospital Cardiac Arrest investigational monitor/defibrillator with CPR feedback - Cardiac Arrest | Phase 2 / Phase 3 | Terminated | University of Chicago | 200 | 2002-12-01 | 2013-09-23 |
| Biphasic Defibrillation Study: Trial to Compare Fixed Versus Escalating Energy Fixed lower-energy defibrillation, Escalating higher-energy defibrillation - Cardiac Arrest | Phase 3 | Completed | Ottawa Hospital Research Institute | 221 | 2001-03-01 | 2025-04-25 |
Heart Arrest (18) · Hypothermia (3) · Diabetes Insipidus (2) · Ventricular Fibrillation (2) · Bradycardia (1) · Consciousness Disorders (1) · Death, Sudden, Cardiac (1) · Edema (1) · Emergencies (1) · Heart Failure (1) · Hypotension (1) · Hypoventilation (1) · Respiratory Insufficiency (1) · Shock (1) · Tachycardia (1)
Cardiovascular Diseases (18) · Heart Diseases (18) · Pathological Conditions, Signs and Symptoms (8) · Pathologic Processes (5) · Signs and Symptoms (4) · Arrhythmias, Cardiac (3) · Body Temperature Changes (3) · Endocrine System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Pituitary Diseases (2) · Urogenital Diseases (2) · Urologic Diseases (2)
Amiodarone (3) · Epinephrine (2) · Hypothermia, Induced (2) · Vasopressins (2) · Arginine Vasopressin (1) · Defibrillators (1) · Diet, Sodium-Restricted (1) · Hydrocortisone (1) · Lidocaine (1) · Methylprednisolone (1) · Phosphocreatine (1) · Renal Dialysis (1) · Saline Solution (1)
Centre Hospitalier Departemental Vendee (2) · University of Washington (2) · Assistance Publique - Hôpitaux de Paris (1) · Carol Bernier (1) · Haukeland University Hospital (1) · Janssen Cilag S.A.S. (1) · Medivance, Inc. (1) · Oregon Health and Science University (1) · Ottawa Hospital Research Institute (1) · Singapore General Hospital (1) · University Hospital, Grenoble (1) · University of Athens (1) · University of Chicago (1) · University of Michigan (1) · Università Vita-Salute San Raffaele (1)
United States (7) · France (4) · Canada (3) · Greece (1) · Italy (1) · Norway (1) · Singapore (1) · South Korea (1)
Jean-Baptiste Lascarrou, MD (2) · Alain Cariou, MD, PhD (1) · Alfred P. Hallstrom, PhD (1) · Carol Bernier, DO (1) · Charis Roussos, MD, PhD (1) · Frank W Moler, MD, MS (1) · Ian Stiell, MD (1) · Joshua Lupton, MD, MPH (1) · Kennon Heard, M.D. (1) · Lance B Becker, MD (1) · Marcus EH Ong, MBBS (1) · Michael Dean, MD, MBA (1) · Myron Weisfeldt, MD (1)
PMID 15657323, PMID 16772625, PMID 17241734, PMID 17353443, PMID 18037223, PMID 18504334, PMID 19451846, PMID 19455024, PMID 19854555, PMID 20466215, PMID 20500876, PMID 20935561, PMID 22353644, PMID 23295834, PMID 23842585, PMID 23860985, PMID 25268768, PMID 25913022, PMID 26940987, PMID 27043165, PMID 27737774, PMID 28904070, PMID 29884735, PMID 30572071, PMID 30922934, PMID 30974188, PMID 33301887, PMID 34990764, PMID 38320013, PMID 38320098, PMID 42383826
K23HL173647 (1), U01HL077863 (1), U01HL094339 (1)