252 completed, 70 unknown, 22 terminated, 16 recruiting. 228 Not applicable, 30 Phase 2, 24 Phase 3, 21 Phase 4, 12 Phase 1.
Follow Hypothermia: new trials by email Literature Review of Hypothermia trials Research Report on Hypothermia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic Surgeries Paracetamol 2 g, Paracetamol 1 g, Normal Saline Placebo - Shivering, Postoperative Shivering | Phase 4 | Not yet recruiting | Assiut University | 150 | 2026-11-01 | 2026-10-02 |
| Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal Anesthesia Dexmedetomidine, Meperidine, Normal Saline 0.9% - Shivering, Hypothermia | Phase 4 | Not yet recruiting | Assiut University | 99 | 2026-11-01 | 2026-10-02 |
| Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section Midazolam and Ketamine, 0.9% Sodium Chloride - Shivering, Post-Spinal Shivering | Phase 4 | Not yet recruiting | Assiut University | 120 | 2026-11-01 | 2026-10-02 |
| Continuous Monitoring of Body Temperature in Neonates During Therapeutic Hypothermia continous temperature measurement - Therapeutic Hypothermia, Neonatal Hypoxic-Ischemic Encephalopathy | Recruiting | Medical University of Graz | 10 | 2026-08-05 | 2026-10-06 | |
| Temperature Optimization in Afebrile Septic PatienTs External Warming - Sepsis, Temperature | Not applicable | Recruiting | Matt Harmon | 50 | 2026-07-17 | 2026-09-21 |
| Targeted Temperature Management on Delayed Neurocognitive Recovery in Older Patients After Major Cancer Surgery Target temperature management, Routine thermal management - Elderly Patients, Cancer Surgery | Not applicable | Not yet recruiting | Peking University First Hospital | 1512 | 2026-06-01 | 2026-06-23 |
| Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass Simultaneous BIS and PSI Monitoring - Cardiopulmonary Bypass, Hypothermia; Anesthesia | Active not recruiting | Sakarya University | 60 | 2026-05-01 | 2026-09-02 | |
| Assessing Local Hypothermia and Endovascular Recanalization for Acute Stroke With a Large Core Infarction intra-arterial local therapeutic hypothermia, Control (Normal saline) - Stroke, Large Ischemic Core | Not applicable | Not yet recruiting | First Affiliated Hospital of Wannan Medical College | 322 | 2026-05-01 | 2026-04-28 |
| Prehospital Use of Forced Air Warming Forced air warming - Hypothermia Due to Cold Environment | Not applicable | Enrolling by invitation | Haukeland University Hospital | 4 | 2026-03-10 | 2026-03-04 |
| Incidence and Risk Factors of Intraoperative Hypothermia in Adult Patients After Protocol Implementation Hypothermia Following Anesthesia | Active not recruiting | Siriraj Hospital | 361 | 2026-02-27 | 2026-03-13 | |
| Arch-Clamping Technique Under Mild Hypothermia in Treating With Acute Type A Aortic Dissection Arch-Clamping Technique under Mild Hypothermia, Arch-Clamping Technique under Moderate Hypothermia, Total Arch Replacement combined Frozen Elephant Trunk Implantation using Bilateral Antegrade Cerebral Perfusion under Moderate Hypothermic Circulatory Arrest - Acute Type A Aortic Dissection, Hypothermia | Not applicable | Recruiting | Beijing Anzhen Hospital | 306 | 2026-02-03 | 2026-04-06 |
| Neuroprotective Effect of Mild Hypothermia Versus Normothermia During Cardiopulmonary Bypass of Coronary Artery Surgery Normothermic cardiopulmonary bypass, Hypothermic cardiopulmonary bypass - Coronary Artery Disease, Brain Injury | Not applicable | Not yet recruiting | Turku University Hospital | 160 | 2026-01-01 | 2026-01-05 |
| The Effect of Warmed Socks Developed as Wearable Technology on Hypothermia, Thermal Comfort Perception and Shivering Heated socks to be developed with wearable technology - Wearable Technology, Hypothermia | Not applicable | Not yet recruiting | Tarsus University | 70 | 2025-12-15 | 2025-09-09 |
| ESOTIP-TEE: Defining an Easy Landmark to Guide Correct Esophageal Probe Placement With Transesophageal Echocardiography Transesophageal Echocardiography - Monitoring, Esophageal Temperature | Recruiting | Institute of Mountain Emergency Medicine | 30 | 2025-12-12 | 2026-05-08 | |
| Effect of a Cooling Helmet on Postoperative Cognitive Dysfunction in Adults Undergoing Open-Heart Surgery Cooling Helmet With Cold Water Circulation, Cooling Helmet With Room-Temperature Water Circulation - Postoperative Cognitive Complications, Open Heart Surgery | Not applicable | Completed | Universitas Indonesia | 153 | 2025-11-30 | 2026-07-09 |
| Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean Sectıon Acupressure - Hypothermia, Shivering | Not applicable | Recruiting | Ondokuz Mayıs University | 57 | 2025-10-14 | 2026-10-07 |
| Long Term Follow-up of Cardiac Arrest Survivors Exposed to Ultra-rapid Cooling Short Form Health Survey (SF-36), Modified Rankin Score (mRS), Activity of Daily Living (ADL) questionnaire - Cardiac Arrest (CA), Resuscitated Sudden Cardiac Death | Recruiting | Assistance Publique - Hôpitaux de Paris | 12 | 2025-06-11 | 2026-03-24 | |
| Management of Healthy Newborn's Body Temperature at Birth Interventional group, Standard of care group - Newborn, Infant, Body Temperature | Not applicable | Withdrawn | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2025-04-30 | 2026-06-18 | |
| The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient Outcomes The rooms of the intervention group patients will be heated before they come to intensive care and the temperature of the room will be increased. - Abdominal Surgery Complications, Hypothermia Following Anesthesia | Not applicable | Recruiting | Cukurova University | 70 | 2025-04-20 | 2025-08-27 |
| Hemoglobin-to-red Blood Cell Distribution Width Ratio and Hypothermia for Elderly Patient body temperature - Transurethral Resection of Prostate Syndrome, Elderly (People Aged 65 or More) | Completed | Ankara Etlik City Hospital | 60 | 2025-04-09 | 2025-06-12 |
Showing 20 of 395. Sign in to see all of them.
Heart Arrest (47) · Premature Birth (18) · Stroke (18) · Hypoxia-Ischemia, Brain (16) · Ischemic Stroke (15) · Body Temperature Changes (14) · Out-of-Hospital Cardiac Arrest (14) · Hyperthermia (12) · Wounds and Injuries (9) · Brain Diseases (8) · Asphyxia Neonatorum (7) · Brain Injuries, Traumatic (7) · Hemorrhage (7) · Surgical Wound Infection (7)
Pathological Conditions, Signs and Symptoms (395) · Signs and Symptoms (392) · Body Temperature Changes (381) · Cardiovascular Diseases (111) · Nervous System Diseases (82) · Pathologic Processes (77) · Central Nervous System Diseases (70) · Heart Diseases (66) · Vascular Diseases (64) · Brain Diseases (58) · Cerebrovascular Disorders (42) · Wounds and Injuries (34) · Urogenital Diseases (28) · Female Urogenital Diseases and Pregnancy Complications (26) · Signs and Symptoms, Respiratory (25)
Hypothermia, Induced (20) · Sodium Chloride (6) · Standard of Care (6) · Propofol (4) · Cool-Down Exercise (3) · Drug Delivery Systems (3) · Ice (3) · Ringer's Solution (3) · Saline Solution (3) · Wearable Electronic Devices (3) · Anesthesia (2) · Body Temperature (2) · Buspirone (2) · Control Groups (2) · Dexmedetomidine (2)
University of Alabama at Birmingham (12) · Haukeland University Hospital (7) · The Cleveland Clinic (7) · Medical University of Vienna (6) · University Hospital Heidelberg (6) · University Hospital Schleswig-Holstein (6) · Assistance Publique - Hôpitaux de Paris (4) · Brighton and Sussex University Hospitals NHS Trust (4) · Life Recovery Systems (4) · NICHD Neonatal Research Network (4) · Oslo University Hospital (4) · Seoul National University Hospital (4) · Stanford University (4) · Sunnybrook Health Sciences Centre (4) · The University of Texas Health Science Center, Houston (4)
United States (76) · Turkey (Türkiye) (29) · France (25) · Germany (25) · Canada (20) · Italy (20) · United Kingdom (19) · China (18) · South Korea (18) · Austria (15) · Norway (14) · Spain (13) · Sweden (10) · Zambia (9) · Denmark (8)
Waldemar A Carlo, MD (10) · Seetha Shankaran, MD (5) · Sven Poli, Dr. med. (5) · Abhik Das, PhD (4) · Barbara J. Stoll, MD (3) · Brenda B. Poindexter, MD MS (3) · Holger Thiele, Associate Professor (3) · Kathleen A. Kennedy, MD MPH (3) · Krisa P. Van Meurs, MD (3) · Kurt Schibler, MD (3) · Ronald N. Goldberg, MD (3) · Undine Pittl, MD (3) · Waldemar A. Carlo, MD (3) · Abbot R Laptook, MD (2) · Abbot R. Laptook, MD (2)
PMID 24524452, PMID 35835616, PMID 19502035, PMID 20042442, PMID 24188226, PMID 7879935, PMID 10763759, PMID 11703564, PMID 11707791, PMID 11812709, PMID 11856793, PMID 11856794, PMID 12165594, PMID 12697600, PMID 12719051, PMID 12771566, PMID 12847056, PMID 15271236, PMID 15294399, PMID 15721471, PMID 15861196, PMID 15885291, PMID 15885292, PMID 1610573, PMID 16199715, PMID 16221780, PMID 1622910, PMID 16324990, PMID 16398377, PMID 16533632, PMID 17079582, PMID 17296783, PMID 17342966, PMID 17695343, PMID 17959975, PMID 18534246, PMID 18633034, PMID 18720323, PMID 18762517, PMID 18829776, PMID 18926277, PMID 19020525, PMID 19252411, PMID 19797281, PMID 19887533, PMID 19896902, PMID 19948631, PMID 2008950, PMID 20113454, PMID 20207600
U10HD021364 (4), U10HD021373 (4), U10HD021385 (4), U10HD027851 (4), U10HD027853 (4), U10HD027856 (4), U10HD027880 (4), U10HD027904 (4), U10HD034216 (4), U10HD040492 (4), U10HD040689 (4), U10HD027871 (3), U10HD036790 (3), U10HD053109 (3), U10HD068244 (3)