Aminophylline: Clinical Trials

33 trials of Aminophylline, newest first

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18 completed, 8 unknown, 2 recruiting, 2 terminated. 7 Phase 2, 7 Phase 4, 6 Phase 1, 5 Not applicable, 4 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 27Completed 4, Not yet recruiting 1, Recruiting 1, Unknown 1
Phase 47Completed 4, Withdrawn 2, Terminated 1
Phase 16Completed 4, Unknown 2
Not applicable5Completed 2, Unknown 2, Recruiting 1
Phase 34Unknown 2, Completed 1, Not yet recruiting 1
Early Phase 12Completed 1, Unknown 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Intravesical Aminophylline to Facilitate Ureteroscopic Access in Children With Distal Ureteral Stones.
Aminophylline, Normal Saline Placebo - Pediatric Urolithiasis, Distal Ureteral Stone
Phase 2RecruitingBeni-Suef University602026-05-092026-06-01
Diuretic Effect of Aminophylline and Furosemide in Adult Patients Undergoing Cardiac Surgical Procedures
Aminophylline, Furosemide - Diuretic Effect, Aminophylline
Not applicableRecruitingCairo University1062026-01-172026-01-21
Prevention of Cisplatin-induced Nephrotoxicity
Aminophylline - Acute Kidney Injury, Renal Tubulopathy
Phase 2 / Phase 3Not yet recruitingMahidol University242025-12-012025-10-07
Heart Rhythm Changes in Patients With Atrial Fibrillation After Cardiopulmonary Bypass: a Retrospective Analysis
The tetralogy of medication regimen - Atrial Fibrillation
CompletedChinese Academy of Medical Sciences, Fuwai Hospital1062024-08-012025-08-22
Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
Aminophylline , magnesium sulphate and placebo - Post-Dural Puncture Headache
UnknownAssiut University6302024-03-012024-02-22
Effects of Aminophylline Bolus on TCI (Target Controlled Infusion) Concentrations at Burst Suppression Occurence
Aminophylline - Anesthesia Brain Monitoring
CompletedUniversity of Padova322023-11-122024-04-25
Effects of Aminophylline Bolus on TCI (Target Controlled Infusion) Concentrations at Return of Responsiveness
Aminophyllin - Propofol, Anesthesia Brain Monitoring
CompletedUniversity of Padova482023-10-252024-04-25
Comparison of Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Prophylaxis of PDPH in Patients With History of PDPH.
Inj Aminophylline 100mg with Inj Acetaminophen 1000mg in 100ml Normal Saline, Inj Aminophylline 100mg , with 0.1mg/kg Dexamethasone in 100ml Normal Saline - Post Dural Puncture Headache
Phase 2CompletedSargodha Medical College502023-08-012026-04-14
Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults
Aminophylline, Frusemide - Acute Kidney Injury
Phase 2 / Phase 3UnknownUniversity of Malaya1322023-07-022023-07-11
Reversal of Complete Heart Block With Aminophylline in Inferior Wall Myocardial Infarction Patients
Aminophylline Injection - Complete Heart Block, Inferior Wall Myocardial Infarction
Phase 4WithdrawnNational Institute of Cardiovascular Diseases, Pakistan2022-12-192025-05-25
Postdural Puncture Headache Relief With Aminophylline and SPGB
conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block - Anesthesia
Phase 4CompletedAin Shams University752022-10-012023-01-11
The Effect of Preoperative Aminophylline
Aminophylline - Recovery From Anesthesia
Phase 1UnknownBeni-Suef University452019-11-012019-11-05
Preventing Acute Kidney Injury (AKI) in Pediatric Patients
Aminophylline, Placebo - Acute Kidney Injury
Phase 3UnknownLe Bonheur Children's Hospital802019-02-072022-04-18
Is Aminophylline More Effective Than Neostigmine/Atropine Mixture in the Treatment of Post-dural Puncture Headache
IV Aminophylline, IV Neostigmine Methylsulfate + Atropine Sulphate - Post-Dural Puncture Headache
Phase 4CompletedDamanhour Teaching Hospital602019-01-012020-02-05
Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
BiPAP, CPAP, Ipratropium - Asthma Acute, Asthma in Children
Not applicableUnknownUniversity of British Columbia1002018-06-012018-05-02
Progesterone and Aminophylline for the Prevention of Preterm Labour
Progesterone, Aminophylline - Premature Obstetric Labor
Phase 1UnknownSt Stephens Aids Trust702017-10-052018-02-28
Effects of Aminophylline on Renal Function and Urine Volume of AKI Patient
aminophylline, frusemide, normal saline - Acute Kidney Injury
Early Phase 1UnknownShanghai Jiao Tong University Affiliated Sixth People's Hospital602016-12-012016-12-06
Aminophylline for Patients With Post-Dural Puncture Headache
Aminophylline, isotonic saline - Post-dural Puncture Headache
Phase 3CompletedThe First Affiliated Hospital of Zhengzhou University1262015-10-012016-10-31
A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe Asthmatics
Aminophylline, Hydrocortisone - Asthma
TerminatedRoyal Brompton & Harefield NHS Foundation Trust52014-06-012015-10-28
A Study to Test the Safety of Combined Dosing With Aminophylline and Ambrisentan in Exercising Healthy Human Volunteers at Simulated High Altitude
Aminophylline 400 mg, Ambrisentan 5 mg, Placebo - Acute Mountain Sickness and Fatigue
Phase 1CompletedRobert J Noveck, M.D.922013-09-012015-11-13

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Conditions studied

Acute Kidney Injury (6)  ·  Post-Dural Puncture Headache (4)  ·  Altitude Sickness (2)  ·  Asthma (1)  ·  Atrial Fibrillation (1)  ·  Bradycardia (1)  ·  Carcinoma, Transitional Cell (1)  ·  Coronary Artery Disease (1)  ·  Critical Illness (1)  ·  Fatigue (1)  ·  Heart Arrest (1)  ·  Hypoxia (1)  ·  Inferior Wall Myocardial Infarction (1)  ·  Motor Activity (1)  ·  Obstetric Labor, Premature (1)

Sponsors

Rush University Medical Center (3)  ·  Beni-Suef University (2)  ·  Stanford University (2)  ·  University of Padova (2)  ·  Ain Shams University (1)  ·  Assiut University (1)  ·  Cairo University (1)  ·  Chinese Academy of Medical Sciences, Fuwai Hospital (1)  ·  Colorado State University (1)  ·  Damanhour Teaching Hospital (1)  ·  King Faisal University (1)  ·  Le Bonheur Children's Hospital (1)  ·  Mahidol University (1)  ·  National Institute of Cardiovascular Diseases, Pakistan (1)  ·  Ospedale Misericordia e Dolce (1)

Countries

United States (11)  ·  Egypt (5)  ·  Italy (3)  ·  China (2)  ·  United Kingdom (2)  ·  Canada (1)  ·  Malaysia (1)  ·  Pakistan (1)  ·  Saudi Arabia (1)  ·  Thailand (1)

Top investigators

Rami Doukky, MD (2)  ·  Ahmed M Shaat, MD (1)  ·  Andrew Menzies-Gow (1)  ·  Anirut Pattaragarn, MD (1)  ·  Azam Shafquat, MD (1)  ·  Changming Wan, MD (1)  ·  Christopher Bell, PhD (1)  ·  Claude A Piantadosi, MD (1)  ·  Dongsheng Guan, MD (1)  ·  Fang Xue, MD (1)  ·  Gary Luckasen, M.D. (1)  ·  Hany F Badawy, MD (1)  ·  Haw Shyan Ng (1)  ·  Mark Johnson, Professor (1)  ·  Mauro Maioli, MD (1)

Results publications

PMID 10484524, PMID 10502118, PMID 10561110, PMID 10742366, PMID 11138732, PMID 11171666, PMID 11181402, PMID 11380813, PMID 11532695, PMID 11734617, PMID 11981083, PMID 12954591, PMID 14602265, PMID 14726035, PMID 15086457, PMID 15313386, PMID 15583947, PMID 15591104, PMID 15840666, PMID 15947981, PMID 16012931, PMID 16049319, PMID 16493070, PMID 16698410, PMID 16816141, PMID 16887430, PMID 17130306, PMID 17936154, PMID 17944638, PMID 18379554, PMID 18926433, PMID 19007588, PMID 20925544, PMID 21545947, PMID 21755342, PMID 21798562, PMID 22395779, PMID 22941478, PMID 23087551, PMID 23093787, PMID 23224354, PMID 24519563, PMID 24711606, PMID 26680684, PMID 29572284, PMID 3046670, PMID 33874898, PMID 3404810, PMID 3517473, PMID 3702223