20 completed, 7 terminated, 5 recruiting, 3 unknown. 38 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 38 | Completed 20, Terminated 7, Recruiting 5, Unknown 3, Withdrawn 2, Not yet recruiting 1 |
| Phase 2 | 4 | Completed 4 |
Follow Tachycardia: new trials by email Literature Review of Tachycardia trials Research Report on Tachycardia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Percutaneous Stellate Ganglion Block as First Line Treatment in Patients With Electrical Storm: the STAR 2 Study L-PSGB first - Electrical Storm, VT | Phase 3 | Not yet recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 180 | 2026-10-01 | 2026-09-29 |
| Efficacy of Adenosine as Compared to Verapamil in Paroxysmal Supraventricular Tachycardia (pSVT) Patients Adenosine, Verapamil Injection - Supraventricular Tachycardia (SVtach) | Phase 3 | Recruiting | Rashid Latif Medical College | 210 | 2024-10-28 | 2024-12-13 |
| The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients Phosphocreatine, Placebo - Hypotension, Consciousness, Level Altered | Phase 3 | Recruiting | Università Vita-Salute San Raffaele | 400 | 2024-10-08 | 2025-08-06 |
| Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm Dexmedetomidine, Normal saline - Ventricular Tachycardia, Ventricular Arrhythmias | Phase 3 | Recruiting | Ottawa Heart Institute Research Corporation | 192 | 2024-05-08 | 2026-07-07 |
| Comparison of IV Lignocain and IV Dexmedetomidine for Attenuation of Laryngoscopic Stress Response to Direct Laryngoscopy Intravenous Dexmedetomidine infusion, Intravenous Lignocain - Tachycardia, Hypertension | Phase 2 / Phase 3 | Completed | Shaheed Mohtarma Benazir Bhutto Institue of Trauma | 62 | 2023-04-13 | 2026-02-03 |
| Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial Control - Catheter Ablation for VT, Treatment - Non-Invasive Radio Ablation for VT - Ventricular Tachycardia | Phase 3 | Recruiting | Ottawa Heart Institute Research Corporation | 244 | 2022-12-06 | 2026-09-30 |
| Efficacy and Safety Study of Etripamil Nasal Spray Self-Administration for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia Etripamil NS 70 mg, Placebo - Tachycardia, Supraventricular, Paroxysmal Supraventricular Tachycardia | Phase 3 | Completed | Corxel Pharmaceuticals | 500 | 2022-06-30 | 2026-11-02 |
| A Study to Systematically Assess the Efficacy and Safety of Intravenous Albumin Infusions in Severe POTS Albumin (Human) 5%, USP, Normal Saline 0.9% Infusion Solution Bag - Postural Orthostatic Tachycardia Syndrome | Phase 3 | Withdrawn | University of Alberta | 2022-01-01 | 2024-09-19 | |
| Etripamil Nasal Spray in Patients With Paroxysmal Supraventricular Tachycardia Etripamil NS 70 mg, Aptar Pharma Nasal Spray Bidose System - Paroxysmal Supraventricular Tachycardia | Phase 3 | Completed | Milestone Pharmaceuticals Inc. | 130 | 2021-12-13 | 2026-05-15 |
| GANGlion Stellate Block for Treatment of Electric storRm (GANGSTER Trial) Left ganglion stellate block, Sham left ganglion stellate block - Ventricular Arrythmia, Ventricular Tachycardia | Phase 3 | Unknown | Institute for Clinical and Experimental Medicine | 80 | 2021-08-21 | 2021-10-19 |
| Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias Cardiac Sympathetic Denervation (CSD), Routine Care - Sudden Cardiac Death, Ventricular Tachycardia | Phase 3 | Unknown | University of California, Los Angeles | 40 | 2021-07-26 | 2024-01-19 |
| Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study Ertugliflozin 5 mg, Placebo 5mg - Heart Failure With Reduced Ejection Fraction, Heart Failure With Mid Range Ejection Fraction | Phase 3 | Terminated | Medical University of Graz | 55 | 2021-06-24 | 2025-06-03 |
| Preventive VT Substrate Ablation in Ischemic Heart Disease Ventricular tachycardia substrate-based radiofrequency ablation - Ventricular Tachycardia, Ventricular Arrythmia | Phase 3 | Unknown | Centro Medico Teknon | 58 | 2021-06-01 | 2023-08-30 |
| Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes) Sodium Zirconium Cyclosilicate (SZC), SZC Placebo - Hyperkalemia | Phase 3 | Terminated | AstraZeneca | 2690 | 2021-04-30 | 2025-06-18 |
| Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility echocardiography, Landiolol - Septic Shock, Tachycardia | Phase 3 | Recruiting | Centre Hospitalier Universitaire, Amiens | 360 | 2021-02-01 | 2025-08-24 |
| A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias. Dantrolene/Ryanodex, Placebo - Ventricular Tachycardia | Phase 2 / Phase 3 | Completed | Vanderbilt University Medical Center | 68 | 2020-08-21 | 2026-10-08 |
| Continuation of Antiarrhythmics Following Ventricular Tachycardia Catheter Ablation Antiarrhythmic drug - Tachycardia, Ventricular, Catheter Ablation | Phase 3 | Terminated | Vanderbilt University Medical Center | 5 | 2019-12-19 | 2022-11-14 |
| Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303 Etripamil NS - Paroxysmal Supraventricular Tachycardia | Phase 3 | Completed | Milestone Pharmaceuticals Inc. | 1116 | 2019-09-23 | 2024-05-23 |
| Safety Study of Intranasal Etripamil for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia (PSVT). NODE-302 Etripamil NS 70 mg, Aptar Pharma Nasal Spray Bidose System - Paroxysmal Supraventricular Tachycardia | Phase 3 | Terminated | Milestone Pharmaceuticals Inc. | 169 | 2018-12-10 | 2024-11-05 |
| Efficacy and Safety of Etripamil for the Termination of Spontaneous Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil, Placebo, Etripamil Test Dose - Paroxysmal Supraventricular Tachycardia | Phase 3 | Terminated | Milestone Pharmaceuticals Inc. | 1097 | 2018-06-18 | 2024-07-12 |
Showing 20 of 38. Sign in to see all of them.
Tachycardia, Ventricular (27) · Ventricular Fibrillation (10) · Arrhythmias, Cardiac (7) · Atrial Fibrillation (6) · Death, Sudden, Cardiac (6) · Heart Diseases (6) · Heart Failure (5) · Cardiovascular Diseases (4) · Tachycardia, Supraventricular (4) · Myocardial Ischemia (3) · Tachycardia, Atrioventricular Nodal Reentry (3) · Hypotension (2) · Postural Orthostatic Tachycardia Syndrome (2) · Atrial Flutter (1)
Cardiac Conduction System Disease (38) · Pathological Conditions, Signs and Symptoms (38) · Pathologic Processes (37) · Cardiovascular Diseases (34) · Heart Diseases (32) · Arrhythmias, Cardiac (31) · Death (7) · Death, Sudden (6) · Heart Arrest (6) · Vascular Diseases (6) · Nervous System Diseases (3) · Tachycardia, Reciprocating (3) · Autonomic Nervous System Diseases (2) · Neurobehavioral Manifestations (2)
Amiodarone (4) · Sotalol (4) · Catheter Ablation (3) · Anti-Arrhythmia Agents (2) · Defibrillators, Implantable (2) · Saline Solution (2) · Adenosine (1) · Albumins (1) · Ambulatory Care Facilities (1) · Cardiac Resynchronization Therapy (1) · Dantrolene (1) · Dexmedetomidine (1) · Digoxin (1) · Electric Countershock (1) · Ethanol (1)
Milestone Pharmaceuticals Inc. (4) · National Heart, Lung, and Blood Institute (NHLBI) (3) · AtriCure, Inc. (2) · Boston Scientific Corporation (2) · Ottawa Heart Institute Research Corporation (2) · Vanderbilt University Medical Center (2) · AstraZeneca (1) · Centre Hospitalier Universitaire, Amiens (1) · Centro Medico Teknon (1) · Corxel Pharmaceuticals (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Helse Stavanger HF (1) · Institute for Clinical and Experimental Medicine (1) · Medical University of Graz (1) · Medtronic Cardiac Ablation Solutions (1)
United States (20) · Canada (11) · China (3) · Germany (3) · Italy (3) · Spain (3) · Argentina (2) · Austria (2) · Brazil (2) · Czechia (2) · France (2) · Hungary (2) · Pakistan (2) · Poland (2) · Belgium (1)
A. Marc Gillinov, MD (1) · Alf Inge Larsen, MD, PhD (1) · Alfred Hallstrom (1) · Andrea Natale, M.D. (1) · Andrea Natale, MD FACC FHRS (1) · Antonio Berruezo, MD, PhD (1) · Arvindh Kanagasundram, M.D (1) · Calum Redpath (1) · Carlos A. Morillo, M.D. (1) · Changsheng Ma (1) · David Bharucha, MD (1) · David J Callans, M.D. (1) · Dirk von Lewinski, Assoc-Prof. (1) · Douglas Russell, MD PhD (1) · Francis Plat, MD (1)
PMID 14563591, PMID 17951266, PMID 21062792, PMID 22962431, PMID 26010524, PMID 26241226, PMID 26718674, PMID 29044787, PMID 30071993, PMID 33107945, PMID 35045327, PMID 35728658, PMID 35738852, PMID 36227461, PMID 36441560, PMID 37230521, PMID 37331368, PMID 37753718, PMID 38032582, PMID 39217453, PMID 40618849, PMID 40894163, PMID 40931676, PMID 41592634, PMID 41668514
2018 (1), R01HL034071 (1), R01HL062154 (1), R01HL115003 (1), U01HL045700 (1)