16 completed, 5 recruiting, 4 terminated, 3 unknown. 33 Phase 2, 9 Phase 1, 4 Phase 3.
Follow Tachycardia: new trials by email Literature Review of Tachycardia trials Research Report on Tachycardia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Using Mirabegron to Control Arrhythmia-1 Mirabegron - Ventricular Arrhythmias and Cardiac Arrest | Phase 2 | Not yet recruiting | Cedars-Sinai Medical Center | 20 | 2026-05-01 | 2026-05-06 |
| Safety, Tolerability, and Exploratory Efficacy of AGP100 in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) AGP100 - Catecholaminergic Polymorphic Ventricular Tachycardia | Phase 2 | Recruiting | Agiana Pharmaceuticals | 10 | 2026-01-02 | 2025-12-26 |
| A Phase 2 Study of CRD-4730 in CPVT CRD-4730, Placebo - Catecholaminergic Polymorphic Ventricular Tachycardia | Phase 2 | Recruiting | Cardurion Pharmaceuticals, Inc. | 12 | 2025-12-01 | 2026-07-09 |
| To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU. Placebo drug ( normal saline ), neostigmine (reversal agent) - Tachycardia, Hypertension | Phase 1 / Phase 2 | Completed | Ziauddin University | 100 | 2025-03-12 | 2025-07-31 |
| The NODE-202 Study (Study of Etripamil Nasal Spray in Pediatric Patients) Etripamil NS - Paroxysmal Supraventricular Tachycardia | Phase 2 | Recruiting | Milestone Pharmaceuticals Inc. | 60 | 2023-12-11 | 2026-07-21 |
| Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) CRD-4730, Placebo - CPVT1, Heart Defects, Congenital | Phase 2 | Terminated | Cardurion Pharmaceuticals, Inc. | 7 | 2023-11-07 | 2026-05-27 |
| Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia (StAR-VT) stereotactic body radiotherapy, 20 Gy in 1 fraction - Ventricular Tachycardia, Arrhythmia | Phase 2 | Enrolling by invitation | McGill University Health Centre/Research Institute of the McGill University Health Centre | 9 | 2023-07-01 | 2025-03-18 |
| StereoTactic Arrhythmia Radiotherapy in the NetherLands no. 2 Stereotactic Arrhythmia Radiotherapy - Ventricular Tachycardia, Arrythmia, Cardiac | Phase 2 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 12 | 2023-05-19 | 2026-01-14 |
| Comparison of IV Lignocain and IV Dexmedetomidine for Attenuation of Laryngoscopic Stress Response to Direct Laryngoscopy Intravenous Dexmedetomidine infusion, Intravenous Lignocain - Tachycardia, Hypertension | Phase 2 / Phase 3 | Completed | Shaheed Mohtarma Benazir Bhutto Institue of Trauma | 62 | 2023-04-13 | 2026-02-03 |
| Venous Ethanol for Ventricular Tachycardia Venous ethanol, Catheter ablation - Ventricular Tachycardia, Ischemic Cardiomyopathy | Phase 2 | Recruiting | The Methodist Hospital Research Institute | 156 | 2023-04-12 | 2026-07-24 |
| SBRT in Chagas Disease Ventricular Tachycardia Stereotactic Body Radiation Therapy - Ventricular Tachycardia, Chagas Disease | Phase 1 / Phase 2 | Unknown | University of Sao Paulo General Hospital | 10 | 2021-07-14 | 2024-07-16 |
| A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias. Dantrolene/Ryanodex, Placebo - Ventricular Tachycardia | Phase 2 / Phase 3 | Completed | Vanderbilt University Medical Center | 68 | 2020-08-21 | 2026-10-08 |
| Phase I/II Randomized Study of Stereotactic Ablative Radiotherapy (SABR) Versus Standard of Care for Refractory Structural Cardiac Arrhythmias (SABR-HEART) stereotactic ablative radiotherapy (SABR), Standard of Treatment - Cardiac Arrhythmia, Cardiac | Phase 1 / Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2019-09-12 | 2024-02-13 | |
| Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia Assess the absorption of oral amiodarone - Supraventricular Tachycardia | Phase 2 | Withdrawn | Centre Hospitalier Universitaire, Amiens | 2016-09-06 | 2017-05-15 | |
| Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia stereotactic body radiotherapy (SBRT) - Ventricular Tachycardia, Cardiomyopathy | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 19 | 2016-07-01 | 2024-08-21 |
| Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm Etripamil, Placebo - Paroxysmal Supraventricular Tachycardia (PSVT) | Phase 2 | Completed | Milestone Pharmaceuticals Inc. | 199 | 2015-03-27 | 2020-12-30 |
| Esmolol to Treat the Hemodynamic Effects of Septic Shock Esmolol, Saline - Septic Shock, Hypotension | Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 40 | 2015-03-01 | 2021-06-28 |
| Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator Eleclazine, Placebo to match eleclazine - Ventricular Arrhythmia | Phase 2 | Completed | Gilead Sciences | 313 | 2014-09-01 | 2019-04-09 |
| Influence of Progesterone Administration on Drug-Induced QT Interval Lengthening Progesterone, Placebo, Ibutilide - Prolonged QT Interval in EKG and Sudden Death | Phase 2 | Completed | Indiana University | 19 | 2013-04-01 | 2015-10-30 |
| Hemodynamic Response of Neuropathic And Non-Neuropathic POTS Patients To Adrenoreceptor Agonist And Antagonist Droxidopa, Atenolol, Placebos - Postural Orthostatic Tachycardia Syndrome, Orthostatic Intolerance | Phase 1 / Phase 2 | Terminated | Beth Israel Deaconess Medical Center | 8 | 2011-08-15 | 2017-05-18 |
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Tachycardia, Ventricular (20) · Arrhythmias, Cardiac (9) · Ventricular Fibrillation (7) · Atrial Fibrillation (3) · Death, Sudden, Cardiac (3) · Hypertension (3) · Heart Arrest (2) · Heart Diseases (2) · Heart Failure (2) · Polymorphic Catecholaminergic Ventricular Tachycardia (2) · Postural Orthostatic Tachycardia Syndrome (2) · Shock, Septic (2) · Tachycardia, Supraventricular (2) · Ventricular Premature Complexes (2)
Cardiac Conduction System Disease (33) · Cardiovascular Diseases (33) · Pathologic Processes (33) · Pathological Conditions, Signs and Symptoms (33) · Heart Diseases (31) · Arrhythmias, Cardiac (24) · Vascular Diseases (4) · Death (3) · Death, Sudden (3) · Infections (3) · Autonomic Nervous System Diseases (2) · Cardiac Complexes, Premature (2) · Cardiovascular Abnormalities (2) · Congenital Abnormalities (2)
Radiosurgery (3) · Saline Solution (3) · Sodium Chloride (3) · Catheter Ablation (2) · esmolol (2) · Acetazolamide (1) · Adrenergic beta-Antagonists (1) · Atenolol (1) · Atomoxetine Hydrochloride (1) · Cardiac Resynchronization Therapy (1) · Clonidine (1) · Dantrolene (1) · Dexmedetomidine (1) · Drinking Water (1) · Droxidopa (1)
Aalborg University Hospital (2) · Beth Israel Deaconess Medical Center (2) · Boston Scientific Corporation (2) · Cardurion Pharmaceuticals, Inc. (2) · Milestone Pharmaceuticals Inc. (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Agiana Pharmaceuticals (1) · Andrea Morelli (1) · AtriCure, Inc. (1) · Biosense Webster, Inc. (1) · Cedars-Sinai Medical Center (1) · Centre Hospitalier Universitaire, Amiens (1) · Chiang Mai University (1) · David Haines, MD (1) · Gilead Sciences (1)
United States (16) · Canada (7) · Germany (4) · Italy (4) · Netherlands (4) · Czechia (3) · Denmark (3) · France (3) · Spain (3) · Pakistan (2) · Belgium (1) · Brazil (1) · Hungary (1) · Israel (1) · Norway (1)
Andrea Morelli, MD (1) · Asma Abdus Salam, Consultant anaesthesiology (1) · David Bharucha, MD (1) · David E Haines, MD (1) · Eli Gang, MD (1) · Francis Plat (1) · James E Tisdale, BSc, PharmD (1) · James Edgerton, MD (1) · Jason Homsy, M.D., Ph.D. (1) · Jeppe H Christensen, MD, DMSci (1) · Joanne Alfieri, MD (1) · Joe Chang, MD (1) · Johannes Sperzel, MD (1)
PMID 10492412, PMID 10793602, PMID 12717123, PMID 1356374, PMID 14563591, PMID 15911704, PMID 17893459, PMID 19687359, PMID 20576632, PMID 21978965, PMID 22091288, PMID 23372884, PMID 23983684, PMID 24002370, PMID 24108526, PMID 24227635, PMID 24495468, PMID 24606242, PMID 24721800, PMID 29261883, PMID 30049309, PMID 30573962, PMID 30586734, PMID 32673517, PMID 34667360, PMID 35066509, PMID 3605668, PMID 37139057, PMID 40894163, PMID 42402640, PMID 6161627, PMID 9366929, PMID 9793671, PMID 9797517
2025 (1), R01HL059459 (1), R01HL061682 (1), UL1TR000445 (1)