54 completed, 15 unknown, 12 recruiting, 5 terminated. 58 Not applicable, 9 Phase 3, 5 Phase 2, 4 Phase 4, 1 Early Phase 1.
Follow Cardiac Resynchronization Therapy: new trials by email Literature Review of Cardiac Resynchronization Therapy trials Research Report on Cardiac Resynchronization Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Magnetic Resonance Imaging Based Risk Stratification for Defibrillator Implantation in Heart Failure Patients Requiring Cardiac Resynchronisation Therapy left bundle branch pacing, Biventricular pacing with defibrillator - Non Ischemic Cardiomyopathy | Not applicable | Recruiting | Velammal Medical College Hospital and Research Institute | 114 | 2026-08-01 | 2026-08-27 |
| AV Nodal Ablation With Conduction System Pacing Versus Cardiac Resynchronization for Symptomatic Heart Failure Patients With Atrial Fibrillation Conduction System Pacing, Cardiac resynchronization therapy - Atrial Fibrillation (AF), Heart Failure | Not applicable | Not yet recruiting | University Medical Center Groningen | 292 | 2026-07-01 | 2026-05-22 |
| Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure Biventricular pacing, Conduction system pacing, Left bundle optimised cardiac resynchronisation therapy - Heart Failure and Reduced Ejection Fraction, Dyssynchrony | Not applicable | Recruiting | Imperial College London | 60 | 2025-11-12 | 2026-02-24 |
| Left Bundle Branch Area Pacing or Biventricular Pacing in AF and Left Ventricular Dysfunction Left bundle branch area pacing, Biventricular pacing - Heart Failure, Block, Heart | Not applicable | Recruiting | srdpiers | 34 | 2024-09-10 | 2024-10-01 |
| Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post TAVI conduction system pacing, right ventricular or biventricular pacing - Atrioventricular Block, Second and Third Degree | Not applicable | Recruiting | Medical University of Silesia | 500 | 2024-02-27 | 2025-06-08 |
| CSP Versus BiVP for Heart Failure Patients With RVP Upgraded to Cardiac Resynchronization Therapy Conduction system pacing, Biventricular pacing - Conduction System Pacing, Biventricular Pacing | Not applicable | Recruiting | The First Affiliated Hospital with Nanjing Medical University | 66 | 2024-01-01 | 2026-05-14 |
| Conduction System Pacing vs Biventricular Pacing in Systolic Dysfunction and Wide QRS: Mortality, Heart Failure Hospitalization or Cardiac Transplant Conduction system pacing, Biventricular pacing - Cardiac Resynchronization Therapy, Heart Failure | Not applicable | Recruiting | Hospital Clinic of Barcelona | 320 | 2023-11-27 | 2026-04-03 |
| Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades Physiological Pacing Upgrade (Conduction System Pacing or Biventricular Pacing), Continued RV Pacing (Right Ventricular Pacing) - Pacing-Induced Cardiomyopathy, Heart Failure | Not applicable | Recruiting | Imperial College London | 155 | 2023-09-04 | 2026-06-23 |
| Biventricular Versus Right Ventricular Pacing Biventricular Pacing, Right Ventricular Pacing - Heart Failure | Not applicable | Terminated | Indiana University | 1 | 2023-08-09 | 2024-12-10 |
| AV Junction Ablation or Optimal Medical Treatment in PatiEnts With Cardiac Resynchronization Therapy and Permanent Atrial Fibrillation Atrioventricular junction ablation in patients with cardiac resynchronization therapy (CRT), Optimal medication treatment in patients with cardiac resynchronization therapy (CRT) - Recurrent Atrial Fibrillation, Persistent Atrial Fibrillation | Not applicable | Recruiting | University Hospital Ostrava | 480 | 2023-04-01 | 2023-06-08 |
| Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy Cardiac Resynchronization Therapy (CRT) - Heart Failure, Pacemaker DDD | Recruiting | Oslo University Hospital | 80 | 2023-03-21 | 2026-10-15 | |
| ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing Cardiac pacing - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD) - Arrhythmias, Cardiac, Atrioventricular Block | Recruiting | University Hospital of Ferrara | 8400 | 2023-01-01 | 2024-03-22 | |
| Cardiac Resynchronization Therapy in Adult Congenital Heart Disease With Systemic Right Ventricle: RIGHT-CRT CRT ON (biventricular pacing) / CRT OFF (inactive or univentricular pacing), CRT OFF (inactive or univentricular pacing) / CRT ON (biventricular pacing) - Congenital Heart Disease, Systemic Right Ventricle | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 26 | 2022-11-15 | 2026-06-30 |
| Conduction System Pacing Versus Biventricular Resynchronization in Patients With Chronic Heart Failure Conduction system pacing, Biventricular pacing - Heart Failure, Left Bundle-Branch Block | Not applicable | Completed | Hospital Moinhos de Vento | 179 | 2022-11-07 | 2025-06-08 |
| Left Bundle Branch Area Pacing Using Conventional Stylet-driven Pacemaker Leads for Cardiac Resynchronization Therapy Left Bundle Branch Area Pacing (LBBAP), Biventricular pacing (BiV) - Heart Failure with Reduced Ejection Fraction | Not applicable | Active not recruiting | AZ Sint-Jan AV | 170 | 2022-09-01 | 2024-09-23 |
| Biomarkers Predicting Atrial High Rate Episodes in Cardiac Implantable Electronic Device Recipients implantable cardiac electronic device recipients - Atrial High Rate Episode, Cardiac Implantable Electronic Device | Unknown | Pusan National University Hospital | 100 | 2022-07-24 | 2022-07-27 | |
| Clinical Efficacy of Left Bundle Branch Area Pacing for Patients With Permanent Atrial Fibrillation and Heart Failure Left bundle branch area pacing, Biventricular pacing - Left Bundle Branch Area Pacing, Biventricular Pacing | Not applicable | Unknown | Fu Wai Hospital, Beijing, China | 60 | 2022-07-18 | 2024-01-10 |
| The Left Bundle Cardiac Resynchronization Therapy Trial Cardiac resynchronization therapy - Left Bundle-Branch Block, Heart Failure | Not applicable | Active not recruiting | Óscar Cano Pérez | 176 | 2022-06-27 | 2025-07-17 |
| Conduction System Pacing vs Biventricular Resynchronization Therapy in Systolic Dysfunction and Wide QRS: CONSYST-CRT. Conduction system pacing, Biventricular pacing - Resynchronization Therapy, Conduction System Pacing | Not applicable | Completed | Hospital Clinic of Barcelona | 130 | 2022-01-17 | 2025-07-10 |
| Conduction System Pacing Versus Biventricular Pacing for Cardiac ResYNChronization Resynchronization with conduction system pacing, Cardiac resynchronization therapy with biventricular stimulation - Dilated Cardiomyopathy with Conduction Defect, Left Bundle-Branch Block | Not applicable | Completed | University Medical Centre Ljubljana | 62 | 2022-01-10 | 2024-11-01 |
Showing 20 of 94. Sign in to see all of them.
Heart Failure (73) · Bundle-Branch Block (9) · Atrial Fibrillation (5) · Atrioventricular Block (5) · Heart Defects, Congenital (5) · Heart Diseases (5) · Heart Failure, Systolic (4) · Ventricular Dysfunction (4) · Arrhythmias, Cardiac (3) · Cardiomyopathies (3) · Cardiomyopathy, Dilated (3) · Ventricular Dysfunction, Left (3) · Bradycardia (2) · Cardiomyopathy, Hypertrophic (2) · Heart Block (2)
Abbott Medical Devices (9) · Medtronic Cardiac Rhythm and Heart Failure (6) · Boston Scientific Corporation (5) · Biotronik SE & Co. KG (4) · Maastricht University Medical Center (4) · Hospital Clinic of Barcelona (3) · Imperial College London (3) · Guy's and St Thomas' NHS Foundation Trust (2) · St. Luke's-Roosevelt Hospital Center (2) · The First Affiliated Hospital with Nanjing Medical University (2) · The Hospital for Sick Children (2) · Universitaire Ziekenhuizen KU Leuven (2) · University of Leeds (2) · AZ Sint-Jan AV (1) · Andreas Flammer (1)
United States (21) · United Kingdom (19) · Italy (13) · France (12) · Germany (11) · Netherlands (11) · Spain (10) · Belgium (8) · Canada (8) · Czechia (7) · Austria (5) · China (5) · Denmark (4) · Hungary (4) · Norway (4)
Jens-Uwe Voigt, MD, PhD (2) · Kevin Vernooy, MD, PhD (2) · Ahran D Arnold, MBBS, BSc, MSc, MRCP, PhD (1) · Alexander Dal Forno, MD (1) · Anders Sommer Knudsen, MD (1) · Andre Zimerman, MD PhD (1) · Andreas J Flammer, MD (1) · Andrew Kaplan, MD (1) · Anita Asgar, MD (1) · Anja Zupan Meznar, MD (1) · Anne B. Curtis, MD, FHRS, FACC (1) · Arthur J Moss, MD (1)
PMID 36700426, PMID 37671601, PMID 14563591, PMID 15152059, PMID 17986493, PMID 18401214, PMID 19038680, PMID 19204305, PMID 19723701, PMID 19800193, PMID 19858419, PMID 20569719, PMID 20620231, PMID 20733097, PMID 20823398, PMID 21087711, PMID 21185401, PMID 21310317, PMID 21339317, PMID 21350054, PMID 21357819, PMID 21382893, PMID 21602574, PMID 21606084, PMID 21658562, PMID 21816309, PMID 21852311, PMID 21900084, PMID 21982313, PMID 22285578, PMID 22348447, PMID 22698490, PMID 22781424, PMID 23040580, PMID 23137504, PMID 23138590, PMID 23183194, PMID 23252875, PMID 23449428, PMID 23500269, PMID 23579010, PMID 23592833, PMID 23614585, PMID 23641006, PMID 23770172, PMID 23801020, PMID 23900696, PMID 23998714, PMID 24014828, PMID 24125796
2016 (1), R01HL080152 (1)