89 completed, 26 unknown, 14 terminated, 13 recruiting. 50 Not applicable, 36 Phase 2, 33 Phase 4, 27 Phase 3, 9 Phase 1.
Follow Albumins: new trials by email Literature Review of Albumins trials Research Report on Albumins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Evaluation of Alb PRF Versus Connective Tissue Graft in Reconstruction of Deficient Interdental Papilla Albumin (5% serum-protein solution containing immunoglobulins), connective tissue graft - Deficient Interdental Papilla | Phase 3 | Not yet recruiting | ahmed mostafa ahmed abo el soud | 28 | 2026-06-20 | 2026-05-19 |
| Albumin in Acute Variceal Bleeding Albumin - Acute Variceal Bleeding, Cirrhosis | Phase 3 | Not yet recruiting | King George's Medical University | 60 | 2026-03-01 | 2026-02-09 |
| Modulation of Cerebral Ischemia by Albumin Albumin infusion, Placebo Injection - Ischemic Stroke | Phase 2 | Recruiting | University Hospital Hradec Kralove | 100 | 2026-02-03 | 2026-05-06 |
| Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2 Albumin, Endovascular treatment - Acute Ischemic Stroke | Phase 3 | Recruiting | Capital Medical University | 1192 | 2025-12-18 | 2026-10-19 |
| A Clinical Comparison of Connective Tissue Graft and Alb-PRF for Rebuilding Interdental Papilla Albumin (5% serum-protein solution containing immunoglobulins), connective tissue graft - Papilla Reconstruction | Phase 3 | Not yet recruiting | shaimaa hamdy | 30 | 2025-09-01 | 2025-08-24 |
| Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff - Pre-Eclampsia | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 62 | 2025-07-01 | 2024-12-06 |
| The Intensive Care Platform Trial Albumin, No albumin use, LMWH in weight-adjusted dose - Intensive Care Patients, Intensive Care Unit Patients | Phase 4 | Recruiting | Anders Perner | 10000 | 2025-06-26 | 2026-10-05 |
| Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE) Human albumin infusion at a modified dosage, Human albumin infusion at a routine dosage, Lactulose - Overt Hepatic Encephalopathy | Not applicable | Recruiting | General Hospital of Shenyang Military Region | 174 | 2025-06-24 | 2025-08-26 |
| Effect of Single vs Repeated Cycles of a Combination of Granulocyte Colony Stimulating Factor and Darbepoetin vs Standard Medical Treatment on Immunometabolic Profile in Patient With Early Decompensated Cirrhosis. Darbepoetin, G-CSF, Lactulose - Decompensated Liver Cirrhosis | Not applicable | Recruiting | Institute of Liver and Biliary Sciences, India | 60 | 2025-06-04 | 2026-05-22 |
| "Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function" Furosemide plus albumin, Furosemide (Diuretic) - Urine Output Decreased | Not applicable | Recruiting | Jose J Zaragoza, MD MSc | 56 | 2025-06-01 | 2026-06-16 |
| Albumin Assisted Diuresis in Patients with Cirrhosis and Ascites Albumin infusion (25% albumin), Normal Saline (0.9% NaCl) - Cirrhosis, Ascites Hepatic | Phase 2 | Recruiting | Anahita Rabiee MD MHS | 20 | 2025-02-28 | 2025-03-11 |
| Comparison of Safety and Efficacy of Tailored Versus Fixed Dose Albumin for the Management of Patients With Cirrhosis and Sepsis Associated Acute Kidney Injury Albumin, Standard Medical Treatment - Liver Cirrhosis, Acute Kidney Injury | Not applicable | Not yet recruiting | Institute of Liver and Biliary Sciences, India | 100 | 2025-01-31 | 2025-02-05 |
| Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin - Pregnancy, Cesarean Delivery | Not applicable | Completed | Sameh Fathy | 162 | 2024-10-27 | 2025-05-21 |
| Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Chinese Subjects With Hemophilia B Previously Treated With FIX Therapy Recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) - Hemophilia B | Phase 3 | Completed | CSL Behring | 23 | 2024-07-28 | 2026-07-23 |
| Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients extended platelet rich fibrin injection in pocket, albumin injection in pocket, scaling and root planing - Periodontitis Stage II, Gingival Pocket | Not applicable | Completed | Mansoura University | 45 | 2024-04-17 | 2025-07-23 |
| Terlipressin in Combined Hepatorenal Syndrome in Patients With Signs of Chronic Renal Disease terlipressin or noradrenalin plus albumin - Liver Cirrhosis, Hepato-Renal Syndrome | Completed | University Hospital Freiburg | 490 | 2024-03-03 | 2025-12-05 | |
| Evaluation of Low-dose Albumin and Midodrine Versus Midodrine Alone in Outcome of Recurrent Ascites in Patients With Decompensated Cirrhosis. Albumin, Midodrine, Standard of Care - Decompensated Cirrhosis | Not applicable | Unknown | Institute of Liver and Biliary Sciences, India | 100 | 2024-02-10 | 2024-02-07 |
| Study on the Role of Human Serum Albumin in Large Acute Ischemic Stroke of Anterior Circulation After Thrombectomy Patients with AIS receive intravascular therapy, and within 10 minutes after the surgery, they are administered 100ml of 20% human albumin intravenously (infused within 30 minutes). - Cerebral Ischemia | Not applicable | Recruiting | Tingyu-Yi | 100 | 2024-01-30 | 2024-10-08 |
| Midodrine Plus Albumin Versus Midodrine Alone to Prevent Cirrhosis Related Complications in Children With Cirrhosis and Ascites Midodrine, albumin, Standard Medical Treatment - Liver Cirrhosis | Not applicable | Completed | Institute of Liver and Biliary Sciences, India | 61 | 2023-12-22 | 2026-03-10 |
| Neutrophil-lymphocyte and Platelet-lymphocyte Ratios and Their Relations to Vascular Comlications and Glycemic Control in Patients With Type 2 Diabetes Attending The Diabetes Center of Assiut University Hospitals Echocardiogram - Vascular Complication, Diabetic | Not yet recruiting | Assiut University | 106 | 2023-12-01 | 2023-10-10 |
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Fibrosis (22) · Liver Cirrhosis (17) · Shock, Septic (12) · Hepatorenal Syndrome (9) · Acute-On-Chronic Liver Failure (8) · Ascites (8) · Sepsis (8) · Hepatic Encephalopathy (6) · Renal Insufficiency (6) · Acute Kidney Injury (5) · Burns (5) · Inflammation (5) · Ischemic Stroke (5) · Shock (5) · Edema (4)
Institute of Liver and Biliary Sciences, India (23) · Grifols Therapeutics LLC (5) · Washington University School of Medicine (5) · Hospital Clinic of Barcelona (3) · Instituto Grifols, S.A. (3) · Post Graduate Institute of Medical Education and Research, Chandigarh (3) · Asan Medical Center (2) · Assiut University (2) · Baxalta now part of Shire (2) · Baylor College of Medicine (2) · CSL Behring (2) · Copenhagen University Hospital, Rigshospitalet (2) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (2) · Hospices Civils de Lyon (2) · Hunter Holmes Mcguire Veteran Affairs Medical Center (2)
United States (32) · India (28) · Spain (14) · Germany (11) · Canada (10) · China (10) · Italy (10) · France (9) · Denmark (6) · South Korea (6) · Sweden (6) · Egypt (5) · United Kingdom (5) · Austria (4) · Mexico (4)
Burton M Wice, PhD (3) · Dominic Reeds, MD (3) · Juan Cordoba, MD (2) · Pietro Caironi, MD (2) · Samuel Sigal, MD (2) · Vicente Arroyo, MD (2) · Adil E Bharucha, MBBS, MD (1) · Agustin Albillos (1) · Ahmed Kareem (1) · Aide McCormick (1) · Alan Tinmouth, MD (1) · Alexander Gerbes (1)
PMID 23872605, PMID 24635772, PMID 30905652, PMID 39375158, PMID 10347109, PMID 11772973, PMID 15740535, PMID 16393283, PMID 16460491, PMID 16552809, PMID 16966752, PMID 18178525, PMID 18251131, PMID 18410283, PMID 18492024, PMID 18547224, PMID 18645164, PMID 19196813, PMID 19251783, PMID 19260050, PMID 19365055, PMID 19483042, PMID 19496683, PMID 19678952, PMID 20457948, PMID 20647554, PMID 20837852, PMID 20920370, PMID 20924555, PMID 21484145, PMID 21546491, PMID 21617168, PMID 22095893, PMID 22732511, PMID 22801062, PMID 23226015, PMID 23934414, PMID 23984731, PMID 24067785, PMID 24076337, PMID 24146883, PMID 24686867, PMID 25099709, PMID 25623044, PMID 25638527, PMID 25954497, PMID 26183122, PMID 26325387, PMID 26474358, PMID 26486704
2019 (3), 2016 (2), 2018 (2), 2008 (1), 2009 (1), 2023 (1), P01DK068055 (1), R01DK088126 (1), R01HL115557 (1), U01NS054630 (1), UL1TR000135 (1)