33 completed, 25 unknown, 17 recruiting, 5 not yet recruiting. 44 Not applicable, 5 Phase 3, 4 Phase 4, 2 Phase 2, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Can Two Dietary Interventions Maintain Weight Loss for 12 Months After GLP-1 Therapy in Adults With Overweight/Obesity? NutriAct plus, Rescue VLCD - Obesity & Overweight, Weight Loss Maintenance | Not applicable | Not yet recruiting | Knut Mai | 292 | 2027-03-01 | 2026-07-20 |
| Comprehensive Rehabilitation Programme in People With Multiple Sclerosis: The RECONNECT-MS Study Individual Physiotherapy, Group Movement Awareness, Group Psychotherapy - Multiple Sclerosis | Not applicable | Not yet recruiting | Charles University, Czech Republic | 45 | 2026-07-01 | 2026-06-24 |
| Extended Ablation Versus Pulmonary Vein Isolation to Treat Persistent Atrial Fibrillation PVI-plus, PVI-only - Atrial Fibrillation (AF) | Not applicable | Recruiting | Charles University, Czech Republic | 450 | 2026-06-01 | 2026-09-24 |
| Endoscopic Ultrasound-Guided Radiofrequency Ablation for Pancreatic Cystic Neoplasms and Pancreatic Neuroendocrine Tumors Endoscopic ultrasound-guided radiofrequency ablation for pancreatic cystic lesions, Endoscopic ultrasound-guided radiofrequency ablation of pancreatic solid lesions - Endoscopic Ultrasound-Guided Radiofrequency Ablation, Pancreatic Neuroendocrine Tumors (pNET) | Not applicable | Recruiting | Institute for Clinical and Experimental Medicine | 50 | 2026-04-11 | 2026-04-17 |
| Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure Ketone Monoester (KE) - Acute Heart Failure (AHF), Cardiogenic Shock | Phase 4 | Recruiting | Institute for Clinical and Experimental Medicine | 12 | 2026-04-04 | 2026-04-14 |
| Hernia Repair Using Rectus Fascia Allograft Allogeneic non-vascularized rectus abdominis fascial graft (NVRF) - Abdominal Wall Hernia | Not yet recruiting | Institute for Clinical and Experimental Medicine | 20 | 2026-02-01 | 2026-01-12 | |
| Evaluate the Performance of the Dexcom G7 Continuous Glucose Monitoring (CGM) System in Critically Ill Patients Undergoing Major Abdominal Surgery and Solid Organ Transplantation Which Require Blood Glucose Monitoring for Intensive Insulin Therapy. Continuous glucose monitor - CGM, Intensive Care (ICU) | Not applicable | Recruiting | Institute for Clinical and Experimental Medicine | 62 | 2026-01-14 | 2026-05-28 |
| Hepatic Venous Pressure Gradient Versus Endoscopic Ultrasound-Guided Portal Pressure Gradient - Comparative Analysis (HEPCA) Hepatic venous pressure gradient measurement, Endoscopic ultrasound-guided portal pressure gradient measurement - Cirrhosis, Portal Hypertension | Not applicable | Recruiting | Military University Hospital, Prague | 40 | 2025-05-30 | 2026-02-20 |
| Per-oral Endoscopic Myotomy (POEM) in Patients with Postfundplication Dysphagia Per Oral Endoscopic Myotomy (POEM) - Dysphagia, Dysphagia, Esophageal | Not applicable | Not yet recruiting | Institute for Clinical and Experimental Medicine | 30 | 2025-04-01 | 2025-03-12 |
| Chronic Kidney Disease Screening Chronic Kidney Diseases | Recruiting | Institute for Clinical and Experimental Medicine | 3000 | 2025-02-24 | 2025-09-04 | |
| Biodegradable Stents in Liver Transplant RecipIents for Treatment of Biliary Anastomotic Strictures ERCP implantation of a biodegradable stent, ERCP implantation of plastic stents - Liver Transplant, Complications, Biliary Anastomotic Stenosis | Not applicable | Recruiting | Institute for Clinical and Experimental Medicine | 70 | 2024-11-01 | 2024-12-04 |
| Cavo-Tricuspid Isthmus Block Durability After Pulsed Electric Field Ablation Catheter ablation of cavotricuspid isthmus using flower configuration of the Farapulse catheter, Catheter ablation of cavotricuspid isthmus using basket configuration of the Farapulse catheter - Flutter, Atrial, Cavotricuspid Isthmus Dependent Right Atrial Flutter | Not applicable | Unknown | Institute for Clinical and Experimental Medicine | 150 | 2024-09-16 | 2024-11-15 |
| Use of Wearables to Detect Infections in Kidney Transplant Recipients Kidney Transplant Infection | Not yet recruiting | Institute for Clinical and Experimental Medicine | 200 | 2024-09-01 | 2024-04-15 | |
| Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure non-contrast chest CT, spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis, Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood - Heart Failure, Pulmonary Hypertension | Recruiting | Institute for Clinical and Experimental Medicine | 230 | 2024-08-23 | 2024-08-27 | |
| The Role of Sugars in Fat Accumulation in the Liver 150g of fat with glucose, 150g of fat with fructose, 150g of fat with sucrose - Fatty Liver Disease | Not applicable | Recruiting | Institute for Clinical and Experimental Medicine | 40 | 2024-06-20 | 2024-12-30 |
| ALSS - DPMAS and Therapeutic Plasma Exchange (TPE), Its Effect on Primary Coagulation, Inflammation and the Function of Vital Organs in ALF or ACLF The artificial liver support system (ALSS) - DPMAS/TPE - Acute Liver Failure | Not applicable | Recruiting | Institute for Clinical and Experimental Medicine | 25 | 2024-04-01 | 2026-01-09 |
| Early Detection of HCV in Injection Drug Users Hepatitis C antibody (anti-HCV) test, Hepatitis C RNA test and genotype test - Hepatitis C Virus Infection | Recruiting | Institute of Health Information and Statistics of the Czech Republic | 3000 | 2023-12-15 | 2025-06-29 | |
| G-POEM for Refractory Gastroparesis After Esophagectomy With Gastric Pull-through Gastroparesis, Esophageal Cancer | Unknown | Institute for Clinical and Experimental Medicine | 30 | 2023-10-12 | 2024-03-15 | |
| Pericoronary Adipocyte Size Gradient Heart transplantation for the final stage of heart failure - Heart Failure, Heart Transplantation | Recruiting | Institute for Clinical and Experimental Medicine | 60 | 2023-06-01 | 2026-01-22 | |
| Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic ANOCA, ANOCA - Angina With Non-obstructive Coronary Arteries | Recruiting | University Hospital, Motol | 1000 | 2023-04-20 | 2025-08-05 |
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Diabetes Mellitus, Type 2 (10) · Heart Failure (7) · Insulin Resistance (7) · Atrial Fibrillation (4) · Diabetes Mellitus (4) · Gastroparesis (4) · Cardiovascular Diseases (3) · Diabetes Mellitus, Type 1 (3) · Obesity (3) · Tachycardia, Ventricular (3) · Atrial Flutter (2) · COVID-19 (2) · Cardiac Output, Low (2) · Colitis, Ulcerative (2) · Colorectal Neoplasms (2)
Warfarin (3) · Biopsy (2) · CD36 Antigens (2) · Fructose (2) · Glucose (2) · Sirolimus (2) · Tacrolimus (2) · Alemtuzumab (1) · Angptl4 protein, mouse (1) · Cardiac Surgical Procedures (1) · Catheter Ablation (1) · Colonoscopy (1) · Control Groups (1) · Coronary Artery Bypass (1) · Diet, Gluten-Free (1)
Czechia (75) · Belgium (4) · Germany (4) · Denmark (3) · Italy (3) · Netherlands (3) · Slovakia (3) · Sweden (3) · Finland (2) · France (2) · United Kingdom (2) · Romania (1) · Spain (1) · United States (1)
Ondrej Viklicky, Prof. (3) · Terezie Pelikanova, Prof., MD (3) · Roman Prymula, Prof. (2) · Ales Linhart, Prof,MD,PhD (1) · Bashar Aldhoon, MD, PhD (1) · C.T. Germer, Prof. (1) · Dagmar Koveslygetyova, Bc (1)
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