120 completed. 120 Phase 2, 36 Phase 1, 17 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 120 | Completed 120 |
| Phase 1 | 36 | Completed 36 |
| Phase 3 | 17 | Completed 17 |
Follow Spinal Cord Injuries: new trials by email Literature Review of Spinal Cord Injuries trials Research Report on Spinal Cord Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI CBD/CBD-A, Placebo - SCI - Spinal Cord Injury, Neuropathic Pain | Phase 1 / Phase 2 | Completed | University of Miami | 6 | 2025-06-16 | 2026-08-14 |
| Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury 4.5mg daily dose of naltrexone - Central Neuropathic Pain, Spinal Cord Injury | Phase 2 | Completed | Medical College of Wisconsin | 11 | 2025-02-01 | 2026-11-02 |
| Access-H20: Sensor-driven Smart Faucet Related Study Water Faucet - Spinal Cord Injuries | Phase 2 | Completed | Old Dominion University | 23 | 2024-02-01 | 2026-05-22 |
| NVG-291 in Spinal Cord Injury Subjects NVG-291, Placebo Injection - Spinal Cord Injuries, Chronic Spinal Cord Injury | Phase 1 / Phase 2 | Completed | NervGen Pharma | 24 | 2023-08-08 | 2026-11-03 |
| Remotely Delivered Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery After Spinal Cord Injury Remote CMR, Remote Exercise - Spinal Cord Injuries, Spinal Cord Diseases | Phase 2 | Completed | University of Minnesota | 19 | 2023-06-01 | 2025-07-08 |
| Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI) Ursolic Acid, Strength Training - Spinal Cord Injuries, Tetraplegia | Phase 2 | Completed | University of Miami | 10 | 2023-03-27 | 2025-05-21 |
| Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury WJ-MSC (XCEL-UMC-BETA), Placebo - Spinal Cord Injury Cervical | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 18 | 2021-10-13 | 2024-01-24 |
| Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury. NMES, Vitamin D, Passive movement - Spinal Cord Injury | Phase 2 / Phase 3 | Completed | VA Office of Research and Development | 6 | 2021-10-01 | 2026-01-23 |
| Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury MT-3921, Placebo - Spinal Cord Injury | Phase 2 | Completed | Tanabe Pharma America, Inc. | 72 | 2021-08-27 | 2025-12-16 |
| Effects of Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury Rimonabant - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | Hospital Nacional de Parapléjicos de Toledo | 8 | 2021-05-12 | 2022-11-15 |
| Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI Romosozumab, Denosumab, Placebo - Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI | Phase 2 | Completed | VA Office of Research and Development | 36 | 2021-03-01 | 2026-09-21 |
| Romosozumab in Women With Chronic SCI Romosozumab, Alendronate - Osteoporosis, Bone Loss | Phase 2 | Completed | Northwestern University | 12 | 2021-03-01 | 2025-09-24 |
| Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury Brivaracetam, Placebo - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | University of Minnesota | 24 | 2021-02-01 | 2025-10-14 |
| Improving Ventilatory Capacity in Those With Chronic High Level SCI Buspirone, Placebo - Spinal Cord Injuries | Phase 2 | Completed | Spaulding Rehabilitation Hospital | 13 | 2020-11-29 | 2025-09-18 |
| Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI) Elezanumab, Placebo - Spinal Cord Injury (SCI) | Phase 2 | Completed | AbbVie | 60 | 2020-09-06 | 2026-02-11 |
| Neuromodulation Techniques After SCI EAW+SCES (exoskelton and spinal cord epidural stimulation), EAW+TS (exoskelton and transspinal stimulation) - Spinal Cord Injury | Phase 2 | Completed | VA Office of Research and Development | 4 | 2020-06-01 | 2026-04-28 |
| Intravesical Lactobacillus to Reduce Urinary Symptoms After Spinal Cord Injury Culturelle 10 Billion CFU Capsule (2 doses), Culturelle 10 Billion CFU Capsule (4 doses) - Spinal Cord Injuries, Neurogenic Bladder | Phase 2 | Completed | Medstar Health Research Institute | 182 | 2020-06-01 | 2026-11-03 |
| Clinical Trial to Evaluate Safety, Tolerability and Efficacy of NFX88 in SCI NFX88 - 1, NFX88 - 2, NFX88 - 3 - Neuropathic Pain, Spinal Cord Injuries | Phase 2 | Completed | Neurofix S.L. | 44 | 2019-10-01 | 2022-12-02 |
| Intravesical Glycosaminoglycan Instillation and Urinary Tract Infection in Acute Spinal Cord Injury iAluRil® intravesical instillations - Spinal Cord Injuries | Phase 1 / Phase 2 | Completed | The University of Western Australia | 10 | 2019-09-18 | 2021-05-03 |
| Multimodality Intervention for Function and Metabolism in SCI Testosterone Undecanoate, hybrid exercise - Spinal Cord Injuries | Phase 2 | Completed | Brigham and Women's Hospital | 84 | 2019-08-23 | 2026-05-07 |
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Quadriplegia (9) · Neuralgia (7) · Spinal Cord Diseases (7) · Chronic Pain (6) · Bone Diseases, Metabolic (5) · Hypotension, Orthostatic (5) · Neurologic Manifestations (5) · Osteoporosis (5) · Urinary Bladder, Neurogenic (5) · Wounds and Injuries (5) · Agnosia (4) · Bone Diseases (4) · Paraplegia (4) · Urinary Tract Infections (4)
Trauma, Nervous System (119) · Central Nervous System Diseases (117) · Nervous System Diseases (117) · Wounds and Injuries (115) · Spinal Cord Diseases (113) · Pathological Conditions, Signs and Symptoms (46) · Signs and Symptoms (45) · Neurologic Manifestations (33) · Pain (12) · Nutritional and Metabolic Diseases (10) · Autonomic Nervous System Diseases (8) · Metabolic Diseases (8) · Neuromuscular Diseases (8) · Cardiovascular Diseases (7) · Female Urogenital Diseases (7)
Lithium Carbonate (4) · Midodrine (4) · Sodium Chloride (4) · Buspirone (3) · Cholecalciferol (3) · NG-Nitroarginine Methyl Ester (3) · Resistance Training (3) · Alendronate (2) · Dextromethorphan (2) · Gentamicins (2) · Methylprednisolone (2) · Teriparatide (2) · Testosterone (2) · Transcranial Direct Current Stimulation (2) · Vitamin D (2)
US Department of Veterans Affairs (12) · VA Office of Research and Development (9) · China Spinal Cord Injury Network (5) · James J. Peters Veterans Affairs Medical Center (5) · Brigham and Women's Hospital (4) · Kessler Foundation (4) · Northwestern University (4) · University of British Columbia (4) · Medstar Health Research Institute (3) · Spaulding Rehabilitation Hospital (3) · University of Miami (3) · Banc de Sang i Teixits (2) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (2) · University of Michigan (2) · University of Minnesota (2)
United States (75) · Canada (14) · Spain (8) · China (6) · Switzerland (5) · Australia (4) · Japan (3) · South Korea (3) · Germany (2) · India (2) · Taiwan (2) · United Kingdom (2) · Czechia (1) · Egypt (1) · Hong Kong (1)
Nancy Rocheleau, Program Analyst (5) · John Fryer, Ph.D. Asst. Director (4) · Thomas J Schnitzer, MD, PhD (4) · Ashraf Gorgey, PhD PT (3) · William Bauman, MD (3) · Christine N. Sang, MD, MPH (2) · Hui Zhu, MD (2) · Jeanne M Zanca, PhD, MPT (2) · Jill Wecht, EdD (2) · Trevor A. Dyson-Hudson, M.D. (2) · Abdalla Awidi, MD (1) · Abdulghani Sankari, MD PhD (1) · Amit Jha, MD (1)
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