1186 completed, 241 unknown, 100 recruiting, 72 terminated. 524 Not applicable, 243 Phase 3, 220 Phase 4, 183 Phase 2, 126 Phase 1.
Follow Osteoporosis: new trials by email Literature Review of Osteoporosis trials Research Report on Osteoporosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMD Romosozumab, Zoledronic Acid 5 MG in 5 ML Injection, Calcium 500 mg and Vitamin D3 800 IU - Osteoporosis in Post-menopausal Women | Phase 4 | Not yet recruiting | Sahlgrenska University Hospital | 216 | 2027-01-11 | 2026-08-19 |
| Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD) Endothelial cell collection - Obesity and Obesity-related Medical Conditions, Diabetes | Recruiting | Bettina Mittendorfer | 100 | 2027-01-01 | 2026-05-07 | |
| Romosozumab and Denosumab Combination Therapy for Osteoporosis Romosozumab, Romosozumab and Denosumab - Postmenopausal Osteoporosis | Phase 4 | Not yet recruiting | Massachusetts General Hospital | 100 | 2027-01-01 | 2026-11-03 |
| Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis Exercise training - Osteopenia, Osteoporosis | Not applicable | Withdrawn | University of Alabama at Birmingham | 2026-12-01 | 2026-07-01 | |
| Exercise and Fall Prevention for Fracture Reduction Guideline-based home exercise training - Osteopenia, Osteoporosis | Not applicable | Not yet recruiting | Wolfgang Kemmler, PhD | 72 | 2026-11-01 | 2026-10-29 |
| Study of TST002 Injection in Postmenopausal Women With Osteoporosis or Low Bone Mass Denosumab, Placebo - Postmenopausal Osteoporosis, Low Bone Mass | Phase 2 | Not yet recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 110 | 2026-10-31 | 2026-09-11 |
| Osteoporosis & Renal Disease: Research in Primary Health Care Services Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA) - Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder | Not yet recruiting | Universidade do Porto | 622 | 2026-10-01 | 2026-09-30 | |
| Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series Spine Fracture, Osteoporosis | Not yet recruiting | Diakonie-Klinikum Stuttgart | 23 | 2026-09-20 | 2026-09-29 | |
| Calcium-Rich Food Versus Calcium Carbonate for Bone Health 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG - Osteopenia, Osteoporosis | Not applicable | Not yet recruiting | Cornell University | 217 | 2026-09-01 | 2026-08-13 |
| Romosozumab Versus Denosumab In Glucocorticoid-induced Osteoporosis: An Extended Observation Of a Clinical Trial at 6 Years Romosozumab, Denosumab - Glucocorticoid-Associated Osteopenia and Osteoporosis | Phase 4 | Not yet recruiting | Tuen Mun Hospital | 54 | 2026-09-01 | 2026-08-12 |
| Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women Full-Spectrum Cannabis Extract 5:1 (CBD:THC) - Chronic Pain, Fibromyalgia | Phase 2 | Not yet recruiting | Associação Pan-Americana Multidisciplinar de Endocanabinologia | 80 | 2026-09-01 | 2026-08-26 |
| Post-osteoporotic Fracture Exercise Program Exercise Program - Osteoporosis, Osteoporotic Fracture | Not applicable | Not yet recruiting | Western University, Canada | 100 | 2026-09-01 | 2026-08-20 |
| Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization - Postmenopausal Osteoporosis | Not applicable | Not yet recruiting | Riphah International University | 40 | 2026-09-01 | 2026-10-15 |
| EFFECTIVENESS AND CLINICAL OPTIMIZATION OF A STANDARDIZED PHYSIOTHERAPY EXERCISE PROGRAM TARGETING BALANCE-POSTURE INTERACTION AND FALL RISK IN OSTEOPOROSIS: A RANDOMIZED CONTROLLED TRIAL Structured Physiotherapy Exercise Program - Osteoporosis, Risk of Falls | Not applicable | Not yet recruiting | Alma Mater Europaea - Slovenia | 88 | 2026-09-01 | 2026-08-13 |
| Effect of Postural Correction Exercises on Pelvic Floor Dysfunction in Postmenopausal Osteoporotic Women Estrogen replacement therapy, General advice, Postural correction exercise program - Osteoporosis, Postmenopausal | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-09-01 | 2026-09-08 |
| GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP) AGN1 LOEP - Osteoporosis | Enrolling by invitation | AgNovos Healthcare, LLC | 305 | 2026-08-25 | 2026-10-30 | |
| The Relationship Between Lipedema and Osteoporosis DXA - Lipedema, Osteoporosis | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 120 | 2026-08-20 | 2026-08-21 | |
| The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation Ibandronate IV, Zoledronic acid IV - Postmenopausal Osteoporosis, Postmenopausal Osteopenia | Phase 4 | Recruiting | National Taiwan University Hospital | 52 | 2026-08-20 | 2026-08-25 |
| Pharmacokinetics of Zoledronic Acid in Patients on Dialysis Zoledronic Acid Injection, 5.0 mg, single dose, Zoledronic Acid Injection, 2.5 mg, single dose - Chronic Kidney Disease, Osteoporosis | Phase 1 | Not yet recruiting | University of Campinas, Brazil | 24 | 2026-08-15 | 2026-09-10 |
| Validation of a Deep Learning Tool for Opportunistic Osteoporosis Screening Using Routine Non-Contrast CT Scans DeepBMD model for osteoporosis risk screening - Osteoporosis | Active not recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 100 | 2026-07-28 | 2026-09-03 |
Showing 20 of 1762. Sign in to see all of them.
Osteoporosis, Postmenopausal (332) · Bone Diseases, Metabolic (278) · Fractures, Bone (120) · Sarcopenia (64) · Motor Activity (62) · Osteoporotic Fractures (53) · Hip Fractures (50) · Breast Neoplasms (49) · Diabetes Mellitus (49) · Spinal Fractures (49) · Cardiovascular Diseases (39) · Obesity (39) · Hypertension (29) · Arthritis, Rheumatoid (27)
Nutritional and Metabolic Diseases (1762) · Metabolic Diseases (1758) · Musculoskeletal Diseases (1742) · Bone Diseases (1735) · Bone Diseases, Metabolic (1484) · Wounds and Injuries (275) · Pathological Conditions, Signs and Symptoms (261) · Signs and Symptoms (169) · Nervous System Diseases (160) · Fractures, Bone (136) · Endocrine System Diseases (123) · Neurologic Manifestations (114) · Pathologic Processes (113) · Neoplasms (103)
Denosumab (111) · Alendronate (108) · Teriparatide (103) · Zoledronic Acid (87) · Cholecalciferol (66) · Risedronic Acid (63) · Calcium (60) · Vitamin D (60) · Ibandronic Acid (42) · Exercise (40) · Absorptiometry, Photon (36) · Calcium Carbonate (31) · romosozumab (30) · Raloxifene Hydrochloride (25) · Resistance Training (21)
Eli Lilly and Company (45) · Amgen (41) · National Taiwan University Hospital (32) · GlaxoSmithKline (24) · Hoffmann-La Roche (24) · Merck Sharp & Dohme LLC (24) · Massachusetts General Hospital (21) · Novartis Pharmaceuticals (20) · Organon and Co (18) · University of Aarhus (16) · Sanofi (15) · University of Alabama at Birmingham (14) · Cairo University (12) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (12) · Assistance Publique - Hôpitaux de Paris (11)
United States (540) · Canada (133) · France (111) · Denmark (93) · China (91) · Turkey (Türkiye) (77) · Italy (71) · United Kingdom (70) · Germany (69) · Taiwan (61) · Spain (59) · Poland (52) · South Korea (47) · Belgium (46) · Australia (44)
Mustafa H Temel, M.D. (10) · Thomas J Schnitzer, MD, PhD (7) · Benjamin Leder, MD (5) · Connie M Weaver, PhD (5) · Ding-Cheng Chan, MD, PhD (5)
PMID 38979716, PMID 21037195, PMID 34231877, PMID 31776637, PMID 11138687, PMID 12795371, PMID 16018754, PMID 18539106, PMID 19362675, PMID 20533525, PMID 21062463, PMID 21148044, PMID 21289258, PMID 21544866, PMID 22152181, PMID 23013236, PMID 23803880, PMID 25030780, PMID 25179289, PMID 25475435, PMID 25527752, PMID 26869384, PMID 27072861, PMID 27385761, PMID 27557655, PMID 27680993, PMID 28473464, PMID 28487349, PMID 28546097, PMID 29105841, PMID 29141853, PMID 29605469, PMID 29661934, PMID 30334093, PMID 31411768, PMID 31665314, PMID 31674644, PMID 32658264, PMID 33813753, PMID 34717922, PMID 35478046, PMID 35538903, PMID 35712111, PMID 36088628, PMID 36588166, PMID 38573517, PMID 39527056, PMID 39606939, PMID 101855, PMID 10826123
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