583 completed, 186 recruiting, 97 terminated, 75 withdrawn. 589 Not applicable, 146 Phase 2, 87 Phase 4, 63 Phase 1, 45 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Breakthrough - T1DM and Chronic Kidney Disease Tegoprubart, Islet Cell Transplant - Diabete Type 1, Chronic Kidney Disease | Phase 1 / Phase 2 | Recruiting | University of Chicago | 10 | 2027-04-29 | 2026-08-20 |
| Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits Sobriety Digital Intervention - Breast Cancer, Alcohol Drinking | Not applicable | Not yet recruiting | University of Miami | 36 | 2027-01-04 | 2026-10-20 |
| Zynrelef Versus Adductor Canal Block ZYNRELEF 400Mg-12Mg Extended-Release Solution, Ultrasound-Guided Adductor Canal Block, Ropivacaine 0.5% Injectable Solution - Knee Osteoarthritis, Arthritis Knee | Phase 4 | Not yet recruiting | University of Miami | 120 | 2027-01-01 | 2026-06-12 |
| The Application of Lifestyle Enhancing Validated Integrative Therapies for Everyday Pain in Cirrhosis High-touch self-management program, Low-touch self-management program - Cirrhoses, Liver | Not applicable | Not yet recruiting | University of Pennsylvania | 625 | 2027-01-01 | 2026-10-02 |
| Lorigerlimab (MGD019) in Patients With Pancreatic Adenocarcinoma and Homologous Recombination Deficiency Lorigerlimab - Pancreatic Adenocarcinoma, Homologous Recombination Deficiency | Phase 2 | Not yet recruiting | University of Miami | 40 | 2027-01-01 | 2026-10-13 |
| RB-PDT for Fusarium Keratitis: The LUMIERE Study Rose Bengal Photodynamic Therapy, Sham RB-PDT - Fusarium Keratitis | Phase 3 | Not yet recruiting | Stanford University | 434 | 2027-01-01 | 2026-08-17 |
| Alexis Retractor in Total Hip Arthroplasty Alexis wound retractor, Standard wound retractor - Hip Osteoarthritis, Hip Arthritis | Not applicable | Not yet recruiting | University of Miami | 202 | 2026-12-01 | 2026-02-05 |
| Haptics in Virtual Reality Haptic-Integrated Interactive Virtual Reality Experience, Traditional Virtual Reality Experience (Hand Controllers) - Literacy, Literacy-language Intervention | Not applicable | Recruiting | University of Miami | 60 | 2026-12-01 | 2026-08-17 |
| Intralesional Chemotherapy (IC): Cisplatin + Epinephrine Cisplatin, Epinephrine injection, Laryngeal Biopsy - Laryngeal Squamous Cell Carcinoma | Phase 2 | Recruiting | University of Miami | 20 | 2026-12-01 | 2026-08-26 |
| Prothrombin Complex Concentrate (PCC) Four Factor Prothrombin Complex Concentrate, ROTEM (Rotational Thromboelastometry) analyzer (TEM International GmbH) - Cardiopulmonary Bypass | Phase 4 | Not yet recruiting | University of Miami | 70 | 2026-12-01 | 2026-10-19 |
| VGFTe-(HD)-OD-2566: Adjunctive Aflibercept Ahmed Glaucoma Valve (AAA) Study Aflibercept Injection, Ahmed Tube Surgery - Glaucoma | Phase 2 | Not yet recruiting | University of Miami | 100 | 2026-12-01 | 2026-10-23 |
| Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer High-Intensity Interval Training (HIIT) Exercise - Prostate Cancer | Not applicable | Recruiting | University of Miami | 50 | 2026-11-30 | 2026-10-23 |
| SEPA+PrEP-Women Pilot Trial for HIV Prevention Among Women at Risk for HIV SEPA+PrEP Women - HIV Infections | Not applicable | Not yet recruiting | University of Miami | 70 | 2026-11-01 | 2026-10-13 |
| Antibiotic-coated Braided Suture Study VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament - Prosthetic Joint Infection, Debridement With Prosthesis Retention | Not applicable | Not yet recruiting | University of Miami | 142 | 2026-11-01 | 2026-07-08 |
| Auricular Vagus Nerve Stimulation Mechanisms for HIV-Associated Peripheral Neuropathy Transcutaneous Auricular Vagus Nerve Stimulation (AVNS) - HIV Associated Polyneuropathy | Not applicable | Recruiting | University of Miami | 70 | 2026-11-01 | 2026-10-06 |
| Alternate Pre-med in Anti-Cluster of Differentiation 20 (CD20) Pilot Project Cetirizine, Diphenhydramine - Multiple Sclerosis | Phase 3 | Not yet recruiting | University of Miami | 60 | 2026-11-01 | 2026-10-02 |
| Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care Model PCIT - Traumatic Brain Injury, Disruptive Behavior | Not applicable | Not yet recruiting | University of Miami | 20 | 2026-11-01 | 2026-05-12 |
| Multi-site Trial of a Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer Dyspnea Intervention, Enhanced Usual Care - Advanced Lung Cancer, Dyspnea | Not applicable | Recruiting | Massachusetts General Hospital | 420 | 2026-11-01 | 2026-10-19 |
| Eye-Tracking Alcohol Warning Alcohol Cancer Warning Labels - Alcohol | Not applicable | Not yet recruiting | University of Miami | 50 | 2026-11-01 | 2026-10-20 |
| Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury Deep Brain Stimulation (DBS), Deep Brain Stimulation (DBS) Device Implant Procedure, Training Sessions - Spinal Cord Injuries | Not applicable | Recruiting | University of Miami | 6 | 2026-10-30 | 2026-06-12 |
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Spinal Cord Injuries (53) · Acquired Immunodeficiency Syndrome (35) · Depression (33) · Anxiety Disorders (26) · HIV Infections (26) · Substance-Related Disorders (26) · Breast Neoplasms (25) · Motor Activity (25) · Obesity (25) · Neoplasms (24) · Prostatic Neoplasms (24) · Wounds and Injuries (16) · Diabetes Mellitus (15) · Glaucoma (14) · Lung Neoplasms (13)
Docetaxel (11) · Doxorubicin (11) · Leucovorin (11) · Exercise (10) · Cisplatin (9) · Dexamethasone (9) · Oxaliplatin (9) · Radiotherapy (9) · Cyclophosphamide (8) · Rituximab (8) · Standard of Care (8) · Therapeutics (8) · Carboplatin (7) · Cognitive Behavioral Therapy (7) · Gemcitabine (7)
United States (980) · Canada (18) · United Kingdom (12) · Australia (9) · South Africa (9) · Italy (8) · Spain (7) · Germany (5) · Brazil (4) · Netherlands (4) · Puerto Rico (4) · Switzerland (4) · Austria (3) · India (3) · Israel (3)
Mark S Nash, PhD (12) · Joseph F. Signorile, PhD (11) · Ranjith Ramasamy, MD (10) · Adam Wanner, MD (9) · Hadar Lev-Tov, MD (9) · Keyvan Nouri, MD (9) · Jill Ehrenreich-May, PhD (8) · Joseph F Signorile, PhD (6) · Joseph Signorile, PhD (6) · Alan Pollack, MD, PhD (5) · Luis E. Raez, MD, FACP (5) · Victor H Hernandez, MD (5) · Bach Ardalan, MD (4) · Frank Penedo, PhD (4)
PMID 21981661, PMID 24960439, PMID 19005394, PMID 19889232, PMID 21070531, PMID 22642525, PMID 22946986, PMID 23046789, PMID 24477186, PMID 27771133, PMID 28464732, PMID 30005555, PMID 32402261, PMID 33182711, PMID 33735476, PMID 36602886, PMID 38588457, PMID 39959603, PMID 40789362, PMID 42098884, PMID 10487591, PMID 10523015, PMID 10540002, PMID 10707230, PMID 10754616, PMID 11227945, PMID 11443202, PMID 12169936, PMID 12176626, PMID 12176628, PMID 12473574, PMID 12777902, PMID 12854101, PMID 14742989, PMID 14742990, PMID 15070752, PMID 15157244, PMID 15233820, PMID 15713712, PMID 15761334, PMID 15949871, PMID 15981038, PMID 15983575, PMID 15996257, PMID 16123718, PMID 16398945, PMID 16570006, PMID 16700640, PMID 16970577, PMID 17012691
U54MD002266 (7), U10DA013720 (3), U24DK122927 (3), U54NS092091 (3), K12CA226330 (2), K24DA040489 (2), P01AA029543 (2), P01HL036588 (2), P30AI073961 (2), R01CA064710 (2), R01CA206456 (2), R01MH095539 (2), U01AA020797 (2), U10EY008057 (2), U24DK130164 (2)