483 completed, 124 unknown, 37 terminated, 33 recruiting. 304 Not applicable, 127 Phase 2, 117 Phase 4, 109 Phase 3, 51 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vitamin D in Diabetic Neuropathy Vitamin D - Diabetic Nephropathy Type 2 | Phase 2 / Phase 3 | Not yet recruiting | Tanta University | 150 | 2026-10-01 | 2026-09-08 |
| Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS) Vitamin D 4000IU daily, Placebo - Polycystic Ovarian Syndrome in Adolescent Females, Vitamin D Deficiency | Not applicable | Recruiting | Yale University | 60 | 2026-09-01 | 2026-08-20 |
| FATIMA Trial: EGCG and Vitamin D3 for Prevention of Fibroid Recurrence Vitamin D and Green Tea, Placebo - Uterine Fibroids (Leiomyoma) | Phase 2 | Recruiting | Sheikh Shakhbout Medical City | 240 | 2026-08-22 | 2026-06-16 |
| Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases PPI, vitamin D, feeding instruction - Laryngomalacia | Not applicable | Recruiting | Minia University | 60 | 2026-04-28 | 2026-08-06 |
| New Treatment of Common Wart PRF group, Vitamin D - Common Warts (Verruca Vulgaris) | Not applicable | Not yet recruiting | Sohag University | 70 | 2026-04-06 | 2026-04-22 |
| Association Between Benign Paroxysmal Positional Vertigo and Vitamin D Deficiency . Vitamin D - Benign Paroxysmal Positional Vertigo (BPPV) | Recruiting | Sohag University | 160 | 2026-04-01 | 2026-06-18 | |
| Pediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta Vitamin D, Calcium - Osteogenesis Imperfecta | Phase 3 | Recruiting | Amgen | 71 | 2026-03-18 | 2026-06-22 |
| Vitamin D for Acute Intracerebral Hemorrhage Vitamin D - Intracerebral Hemorrhage | Not applicable | Recruiting | The University of Hong Kong | 40 | 2026-03-01 | 2026-05-06 |
| Impact of Supplementation With Synbiotics and Prebiotics on Cognitive Decline Associated With Neoadjuvant Chemotherapy in First-line Patients With Breast Cancer Synbiotics Blend, Synbiotics + Vitamin D, Prebiotic - Chemobrain, Breast Cancer | Not applicable | Enrolling by invitation | Instituto Jalisciense de Cancerologia | 80 | 2026-02-27 | 2026-03-12 |
| Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT) Vitamin D (VitD), Placebo, Photodynamic therapy (PDT) - Nonmelanoma Skin Cancer, Basal Cell Carcinoma | Not applicable | Recruiting | Case Comprehensive Cancer Center | 54 | 2026-02-25 | 2026-08-18 |
| Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease Atorvastatin (Lipitor), Vitamin D - Thyroid Eye Disease, TED, Graves Ophthalmopathy | Not applicable | Recruiting | Taipei Veterans General Hospital, Taiwan | 120 | 2026-02-24 | 2026-04-30 |
| Effect of Local Use of Vitamin D on the Rate of Canine Distillization: a Split Mouth Randomized Control Trial Experimental: 1,25 DHC injection, Placebo: plain DMSO solvent - Malocclusion of Anterior Teeth | Phase 1 | Recruiting | Foundation University Islamabad | 30 | 2026-02-20 | 2026-03-18 |
| Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Pylori Infection Vonoparazan, Vitamin D, Probiotic - HELICOBACTER PYLORI INFECTIONS, Helicobacter Infection | Phase 2 | Recruiting | Tanta University | 132 | 2026-02-15 | 2026-09-09 |
| Vitamin D (Bio)Fortified Shopping Baskets to Improve Vitamin D Status Vitamin D (bio)fortified food basket, Control food basket - Vitamin D Biofortification, Vitamin D Fortification | Not applicable | Enrolling by invitation | University of Ulster | 160 | 2026-02-12 | 2026-05-06 |
| Effects of Total Thyroid Removal on Parathyroid Function and Quality of Life high-dose calcium (400 mg x 4), vitamin D (19 mikg x 4), and active vitamin D supplementation (2 mikg x 2), Ommit routine blood test post operative day 1 - Hypoparathyroidism Post-surgical, Quality of Life | Not applicable | Enrolling by invitation | Aarhus University Hospital | 150 | 2026-01-01 | 2026-02-02 |
| Effect of Vitamin D and Branched-chain Amino Acids on Physical Performance and Biomarkers of Muscle Fatigue in Runners Training program, Branched-Chain Amino Acids, Vitamin D - Healthy Adult Male, Runners | Not applicable | Not yet recruiting | Pedro Julian Flores Moreno | 64 | 2026-01-01 | 2026-01-12 |
| Regime for Vitamin D Maintenance in Post-Operative Patients Vitamin D - Sarcopenia | Phase 3 | Recruiting | Sengkang General Hospital | 100 | 2026-01-01 | 2026-05-04 |
| Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care - Upper GI Cancer | Not applicable | Enrolling by invitation | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 110 | 2026-01-01 | 2026-10-20 |
| Effects of Vitamin D in Patients Undergoing Fixed Orthodontic Mechanotherapy Vitamin D (Calcitriol), Placebo - Malocclusions | Not applicable | Not yet recruiting | Hospital Universiti Sains Malaysia | 48 | 2025-12-30 | 2025-12-23 |
| Vitamin D, Nerve Growth Factor and Nerve Conduction Studies in Adult Male Type 2 Diabetic Neuropathy Patients nerve conduction studies, Nerve Growth Factor, 25(OH) vitamin D - Diabetic Neuropathy | Not yet recruiting | Aswan University | 57 | 2025-12-01 | 2025-11-19 |
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Vitamin D Deficiency (180) · Osteoporosis (53) · Bone Diseases, Metabolic (39) · Obesity (28) · COVID-19 (27) · Insulin Resistance (25) · Diabetes Mellitus (24) · Breast Neoplasms (22) · Diabetes Mellitus, Type 2 (18) · Inflammation (15) · Renal Insufficiency, Chronic (13) · Diabetes Mellitus, Type 1 (12) · Osteoporosis, Postmenopausal (11) · Prostatic Neoplasms (11) · Asthma (10)
Assiut University (11) · Brigham and Women's Hospital (9) · Cairo University (9) · Massachusetts General Hospital (9) · University of Wisconsin, Madison (7) · Ain Shams University (6) · Amgen (6) · Wake Forest University Health Sciences (6) · Aga Khan University (5) · Coordinación de Investigación en Salud, Mexico (5) · Stanford University (5) · Universitas Indonesia (5) · University of Aarhus (5) · Washington University School of Medicine (5) · Alliance for Clinical Trials in Oncology (4)
United States (242) · Canada (52) · Egypt (42) · Israel (24) · Mexico (23) · China (21) · Pakistan (21) · Spain (20) · Germany (18) · United Kingdom (18) · France (17) · Denmark (16) · Indonesia (16) · Italy (16) · India (14)
Susan L Greenspan, MD (4) · Francine M Ducharme, MD (3) · Abhishek Bhartia, ME (2) · Anupama Singh, MD (2) · Benjamin U Nwosu, MD (2) · Erin Gaffney-Stomberg, Ph.D., R.D. (2) · Etan Orgel, MD (2) · Hope A Weiler, PhD (2) · Ishir Bhan, MD MPH (2) · Jitender Nagpal, MD (2)
PMID 33305842, PMID 39077939, PMID 38979716, PMID 30009185, PMID 35018442, PMID 12791627, PMID 14717616, PMID 15113819, PMID 15209957, PMID 1550069, PMID 15886381, PMID 16467232, PMID 16467233, PMID 16467234, PMID 16481635, PMID 16481636, PMID 16609086, PMID 16880313, PMID 17277040, PMID 17341712, PMID 17405972, PMID 17502530, PMID 17582069, PMID 17634462, PMID 17720017, PMID 17911175, PMID 17925539, PMID 17974532, PMID 18025884, PMID 18180395, PMID 18192127, PMID 18235052, PMID 18299491, PMID 18302509, PMID 18319414, PMID 18326608, PMID 18387220, PMID 18400738, PMID 18419802, PMID 18489937, PMID 18502208, PMID 18663162, PMID 18822620, PMID 18977726, PMID 19001202, PMID 19005970, PMID 19063829, PMID 19075260, PMID 19099529, PMID 19116321
2017 (4), 2016 (3), 2008 (2), 2015 (2), 2018 (2), U10CA031946 (2), 1RC1HD063562 (1), 2005 (1), 2009 (1), 2019 (1), 2023 (1), K01HL128791 (1), K23AG040708 (1), K23AR048205 (1), K23AR050995 (1)