Urinary Tract Infections: Clinical Trials

414 completed, 123 unknown, 71 recruiting, 55 terminated. 258 Not applicable, 103 Phase 4, 83 Phase 2, 75 Phase 3, 44 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	258	Completed 139, Unknown 40, Recruiting 24, Terminated 21, Active not recruiting 11, Not yet recruiting 10, Withdrawn 8, Enrolling by invitation 5
Phase 4	103	Completed 45, Unknown 19, Terminated 13, Recruiting 11, Withdrawn 9, Active not recruiting 3, Enrolling by invitation 1, Not yet recruiting 1, Suspended 1
Phase 2	83	Completed 51, Unknown 16, Terminated 6, Recruiting 5, Withdrawn 4, Suspended 1
Phase 3	75	Completed 47, Terminated 9, Unknown 9, Recruiting 6, Not yet recruiting 2, Withdrawn 2
Phase 1	44	Completed 25, Recruiting 6, Unknown 6, Withdrawn 4, Terminated 2, Not yet recruiting 1
Early Phase 1	13	Completed 4, Not yet recruiting 2, Terminated 2, Unknown 2, Withdrawn 2, Recruiting 1

Follow Urinary Tract Infections: new trials by email Literature Review of Urinary Tract Infections trials Research Report on Urinary Tract Infections

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Antibiotics for Kidney Transplant Recipients Trimethoprim-Sulfamethoxazole (TMP-SMX), Usual Care - Kidney Transplant, Urinary Tract Infection(UTI)	Phase 4	Not yet recruiting	University of California, San Francisco	50	2028-10-01	2026-09-11
School-Based Bladder Health Intervention Bladder Health Education - Urinary Dysfunction, Lower Urinary Tract Symptoms	Not applicable	Withdrawn	Stanford University		2028-01-01	2026-05-07
Prediction and Prevention of Bloodstream Infections After Kidney Transplantation Pivmecillinam, Placebo - Kidney Transplant Infection, Bloodstream Infection	Phase 3	Not yet recruiting	Susanne Dam Nielsen, MD, DMSc	180	2027-01-01	2026-10-16
Vitamin C and Hiprex in rUTI Methenamine Hippurate 1g BD, Methenamine Hippurate 1g BD + Vitamin C 1g BD - Urinary Tract Infections	Early Phase 1	Not yet recruiting	University Hospitals of North Midlands NHS Trust	20	2027-01-01	2026-02-11
De-implementing PreOp Urine Testing Interventional Project Site Visit - Urinary Tract Infection, Asymptomatic Bacteriuria	Not applicable	Not yet recruiting	VA Office of Research and Development	6	2026-12-31	2026-02-13
Genitourinary Study of Fostering Lactobacillus to Optimize the Microbiome in Women's Health (GUD-FLORA) Lactobacillus crispatus probiotic - Recurrent UTIs	Phase 1	Withdrawn	Duke University		2026-12-01	2026-08-28
Prevalence of Asymptomatic Bacteriuria Among Pregnant Women With Pre-eclampsia in Women Health Hospital Assiut University Pre-Eclampsia, Asymptomatic Bacteriuria		Not yet recruiting	Assiut University	129	2026-11-01	2026-10-08
Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis) Dietary Supplement containing probiotics, Placebo - Recurrent Urinary Tract Infections	Not applicable	Active not recruiting	Synbalance S.r.l.	70	2026-10-14	2026-10-21
Automatic Versus As-Needed Follow-up After Hospitalization for Children With Medical Complexity Automatic follow-up recommendation, As-needed follow-up recommendation - Children With Medical Complexity, Respiratory Tract Infections (RTI)	Not applicable	Not yet recruiting	Seattle Children's Hospital	160	2026-10-01	2026-10-08
Prospective Registry of Exposure to Gepotidacin (PREG) None (Observational study) - Sexually Transmitted Diseases		Not yet recruiting	GlaxoSmithKline	614	2026-09-30	2026-09-30
A Study in Pediatric Participants Aged ≥2 to <12 Years With a Suspected or Confirmed Bacterial Infection or Receiving Prophylaxis Antibiotics Gepotidacin, SOC - Urinary Tract Infections	Phase 1	Not yet recruiting	GlaxoSmithKline	25	2026-09-18	2026-09-28
INterest of the Negative Predictive Value of Integrons in the reduCtion of Large Broad-spectrum anTibiotics Consumption for Urinary Tract infectionS Detection of integrons, Gold standard - Drug Resistance, Microbial, Biomarkers	Not applicable	Not yet recruiting	University Hospital, Limoges	204	2026-09-15	2026-07-01
Rapid UTI Diagnostics in Lower Urinary Tract Dysfunction Among Catheter Users urine Resazurin Reduction Ratio, USQNB - Neurogenic Bladder Disorder, Lower Urinary Tract Disorder	Not applicable	Not yet recruiting	Medstar Health Research Institute	100	2026-09-01	2026-09-11
Emotional Urinary Tract Infection Urinary Tract Infection(UTI), Recurrent Urinary Tract Infections		Not yet recruiting	Northwell Health	170	2026-08-28	2025-09-24
Urine Collection and Novel UTI Biomarkers in Children and Older Adults UTI - Urinary Tract Infection		Recruiting	Queen's University, Belfast	230	2026-08-27	2026-10-15
Clinical Efficacy of Stopping Oral Antibiotics When Symptoms Stop, Compared to 'Finishing the Course' Antibiotics for duration of symptoms, Antibiotics for duration of prescribed course - Urinary Tract Infection, Cellulitis	Phase 4	Recruiting	Murdoch Childrens Research Institute	200	2026-08-18	2026-08-21
Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD Gentamicin, Lactobacillus Rhamnosus GG - Spinal Cord Injury, Neurogenic Bladder (NB)	Early Phase 1	Not yet recruiting	Medstar Health Research Institute	48	2026-08-01	2026-08-21
Prophylactic Antibiotics for Outpatient Urethral Bulking Bactrim (800/160 mg), Keflex (500 mg), Cipro (250 mg), or Macrobid (100mg) - Urinary Tract Infections, Stress Urinary Incontinence	Phase 4	Recruiting	University of Miami	150	2026-08-01	2026-08-20
A Study to Evaluate Gepotidacin Exposure in Breast Milk of Healthy Lactating Women Gepotidacin - Urinary Tract Infections	Phase 1	Recruiting	GlaxoSmithKline	8	2026-07-23	2026-09-30
Precision Management of Urinary Tract Symptoms in Older Women Antibiotics - Urinary Tract Infection (Diagnosis)	Phase 3	Recruiting	Megan Bradley	90	2026-07-23	2026-10-22

Showing 20 of 759. Sign in to see all of them.

Narrower conditions

Bacteriuria (44)  ·  Sepsis (35)  ·  Infections (31)  ·  Pneumonia (30)  ·  Respiratory Tract Infections (27)  ·  Escherichia coli Infections (24)  ·  Disease (23)  ·  Cystitis (22)  ·  Urinary Bladder, Neurogenic (22)  ·  Schistosomiasis haematobia (21)  ·  Spinal Cord Injuries (21)  ·  Urinary Retention (21)  ·  Bacterial Infections (20)  ·  Pyelonephritis (20)

Broader conditions

Female Urogenital Diseases and Pregnancy Complications (759)  ·  Male Urogenital Diseases (759)  ·  Urogenital Diseases (759)  ·  Female Urogenital Diseases (758)  ·  Urologic Diseases (748)  ·  Infections (728)  ·  Pathological Conditions, Signs and Symptoms (206)  ·  Pathologic Processes (136)  ·  Respiratory Tract Diseases (78)  ·  Signs and Symptoms (77)  ·  Urinary Bladder Diseases (70)  ·  Bacterial Infections and Mycoses (68)  ·  Nervous System Diseases (64)  ·  Disease Attributes (54)  ·  Lung Diseases (53)

Interventions

Nitrofurantoin (32)  ·  Ciprofloxacin (24)  ·  Trimethoprim, Sulfamethoxazole Drug Combination (22)  ·  Fosfomycin (19)  ·  Levofloxacin (13)  ·  methenamine hippurate (11)  ·  Anti-Bacterial Agents (10)  ·  Ertapenem (10)  ·  Gentamicins (10)  ·  Trimethoprim (10)  ·  Mannose (8)  ·  Amikacin (7)  ·  gepotidacin (7)  ·  Amoxicillin (6)  ·  Anti-Infective Agents (6)

Sponsors

GlaxoSmithKline (14)  ·  Leiden University Medical Center (9)  ·  London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (9)  ·  Baylor College of Medicine (7)  ·  Merck Sharp & Dohme LLC (7)  ·  National Center for Complementary and Integrative Health (NCCIH) (7)  ·  Assistance Publique - Hôpitaux de Paris (6)  ·  Assiut University (6)  ·  Mayo Clinic (6)  ·  Pathnostics (6)  ·  University Hospital, Basel, Switzerland (6)  ·  University of California, San Francisco (6)  ·  University of Washington (6)  ·  University of Wisconsin, Madison (6)  ·  VA Office of Research and Development (6)

Countries

United States (249)  ·  France (53)  ·  Canada (45)  ·  Italy (30)  ·  United Kingdom (30)  ·  Denmark (25)  ·  Spain (25)  ·  Netherlands (21)  ·  Switzerland (21)  ·  Israel (20)  ·  Turkey (Türkiye) (19)  ·  Sweden (17)  ·  China (16)  ·  Egypt (16)  ·  Germany (16)

Top investigators

Florian Wagenlehner, Prof. (4)  ·  Barbara Trautner, MD (3)  ·  David Sheyn, MD (3)  ·  Ann E Stapleton, MD (2)  ·  Antonella Toffolo, Dr (2)  ·  Charlesnika Tyon Evans, PhD MPH BS (2)  ·  Christian Backer Mogensen (2)  ·  Daniele Porru, MD (2)  ·  Dave Baunoch, PhD (2)  ·  Eva Hummers-Pradier, Prof. Dr. (2)

Results publications

PMID 37068952, PMID 37947276, PMID 34184246, PMID 36041061, PMID 18762516, PMID 19670912, PMID 20156062, PMID 20211892, PMID 20570319, PMID 21303745, PMID 21813209, PMID 23481118, PMID 27787564, PMID 29339393, PMID 34593497, PMID 34978887, PMID 35349162, PMID 36255258, PMID 36271314, PMID 38096261, PMID 38342126, PMID 39698942, PMID 40372095, PMID 40924001, PMID 40924012, PMID 41399629, PMID 41495938, PMID 42682990, PMID 10334980, PMID 10471979, PMID 10505128, PMID 10685584, PMID 10925088, PMID 11023955, PMID 11166145, PMID 11176403, PMID 11857671, PMID 11955556, PMID 12135844, PMID 12376503, PMID 12563043, PMID 12861145, PMID 12894267, PMID 13380946, PMID 15121942, PMID 1555145, PMID 16238023, PMID 16352625, PMID 16458626, PMID 16647928

NIH funding

2016 (3), 2019 (3), 2023 (3), 2008 (2), 2015 (2), 2017 (2), 2018 (2), 2025 (2), 2014 (1), F31AT000623 (1), I01RD000425 (1), K23AG028691 (1), KL2RR024138 (1), P01DK053369 (1), P30AG021342 (1)