579 unknown. 579 Phase 3, 161 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 579 | Unknown 579 |
| Phase 2 | 161 | Unknown 161 |
Follow Nervous System Diseases: new trials by email Literature Review of Nervous System Diseases trials Research Report on Nervous System Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Decreasing Postoperative Blood Loss and Seizures by Timing of Intravenous Tranexamic Acid 2 Pilot Trial Before CPB Tranexamic Acid, After CPB Tranexamic Acid, Before CPB Placebo - Bleeding, Surgical Blood Loss | Phase 3 | Unknown | Hamilton Health Sciences Corporation | 40 | 2025-01-01 | 2024-10-02 |
| Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke Tirofiban Hydrochloride, Standard medical treatment (SMT) - Acute Stroke, Ischemic Stroke, Acute | Phase 2 / Phase 3 | Unknown | Capital Medical University | 302 | 2024-11-20 | 2024-10-29 |
| Lateral Cord Magnetic Stimulation For Refractory Spastic Cerebral Palsy Magnetic Spinal Stimulation - Spastic Cerebral Palsy, Dysarthria | Phase 2 / Phase 3 | Unknown | Sociedad Argenttina de Neuromodulación | 20 | 2024-11-18 | 2023-11-21 |
| Does Perioperative Intravenous Magnesium Affect Postoperative Quality of Recovery in Craniotomy Surgery Patients? IV magnesium sulfate, Placebo - Brain Tumor, Surgery | Phase 3 | Unknown | Thomas Jefferson University | 110 | 2024-11-01 | 2023-04-12 |
| Cannabidiol's Role in Dementia Management Cannabidiol Oil - Dementia, Vascular, Dementia, Mixed | Phase 2 / Phase 3 | Unknown | Hospital Pengajar Universiti Putra Malaysia | 486 | 2024-09-01 | 2024-07-23 |
| Ticagrelor Versus Cilostazol in Ischemic Stroke Ticagrelor 90 MG, Cilostazol 100 MG - Ischemic Stroke | Phase 3 | Unknown | Kafrelsheikh University | 900 | 2024-08-30 | 2024-08-20 |
| Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-D ) Emergency Stroke Unit based on 0.23-T MRI, Standard stroke unit - Ischemic Stroke, Acute | Phase 3 | Unknown | Beijing Tiantan Hospital | 600 | 2024-08-10 | 2024-10-01 |
| Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI) Whole blood transfusion, Blood components transfusion - Traumatic Brain Injury | Phase 3 | Unknown | Oregon Health and Science University | 100 | 2024-08-01 | 2024-04-02 |
| A Eight-Week Study of NLS-2 (Mazindol Extended Release) in Participants With Narcolepsy Type 1 NLS-2, Placebo - Narcolepsy Type 1, Narcolepsy With Cataplexy | Phase 3 | Unknown | NLS Pharmaceutics | 48 | 2024-07-15 | 2024-05-21 |
| Efficacy and Safety of NestaCell® in Huntington's Disease NestaCell® - Huntington Disease | Phase 3 | Unknown | Azidus Brasil | 120 | 2024-06-08 | 2023-10-24 |
| Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery Dexmedetomidine, Fentanyl - Anesthesia and Analgesia, Anesthesia, Endotracheal | Phase 2 / Phase 3 | Unknown | Universitas Indonesia | 104 | 2024-06-01 | 2024-04-30 |
| Safety and Efficacy of Zolpidem in the Long-Term Treatment of Insomnia Sublingual Tablet - Chronic Insomnia | Phase 3 | Unknown | EMS | 358 | 2024-06-01 | 2023-09-07 |
| A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy pregabalin sustained-release tablets, Placebo - Painful Diabetic Neuropathy | Phase 3 | Unknown | CSPC Ouyi Pharmaceutical Co., Ltd. | 358 | 2024-05-15 | 2024-04-30 |
| Comparison of the Ultrasound-guided Paravertebral Nerve Block With Liposomal Bupivacaine Versus Ropivacaine for Post-Surgical Pain After Video-Assisted Thoracoscopic Surgery Liposomal bupivacaine, Ropivacaine - Analgesia | Phase 3 | Unknown | Feng Gao | 84 | 2024-05-10 | 2024-05-08 |
| Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars systemic proteolytic enzyme (Tibrolin), Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg - Post Operative Pain | Phase 3 | Unknown | University of Baghdad | 55 | 2024-05-08 | 2024-05-08 |
| Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo Diazepam 5mg, Diazepam 10 mg, Placebo - Vertigo, Peripheral | Phase 3 | Unknown | University of Monastir | 1000 | 2024-05-01 | 2024-04-02 |
| Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment Semaglutide, Low calorie diet - Idiopathic Intracranial Hypertension | Phase 3 | Unknown | Capital Medical University | 74 | 2024-05-01 | 2024-04-12 |
| Dexmedetomidine Premedication for Post-anaesthesia Sleep Disturbance Normal Saline, Dexmedetomidine - Postoperative Sleep Disturbance | Phase 3 | Unknown | The First Affiliated Hospital of Xiamen University | 110 | 2024-05-01 | 2024-04-16 |
| Liposomal Bupivacaine Use in Alveolar Bone Graft Patients Liposomal Bupivacaine, Bupivacain, Epinephrine - Cleft Lip and Palate | Phase 3 | Unknown | Kerry O'Rourke | 60 | 2024-04-24 | 2024-07-03 |
| Effect of Intravenous Nalbuphine and Magnesium Sulfate on Emergence Agitation in Pediatric Nalbuphine Versus Magnesium Sulfate - Emergence Delirium | Phase 3 | Unknown | Assiut University | 105 | 2024-04-02 | 2024-03-12 |
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Stroke (56) · Ischemic Stroke (55) · Agnosia (50) · Brain Neoplasms (25) · Multiple Sclerosis (20) · Alzheimer Disease (19) · Pain (19) · Parkinson Disease (16) · Migraine Disorders (15) · Neuralgia (15) · Peripheral Nervous System Diseases (14) · Diabetic Neuropathies (13) · Pain, Postoperative (12) · Brain Injuries, Traumatic (11) · Chronic Pain (11)
Central Nervous System Diseases (313) · Brain Diseases (274) · Pathological Conditions, Signs and Symptoms (234) · Signs and Symptoms (182) · Neurologic Manifestations (175) · Cardiovascular Diseases (152) · Vascular Diseases (145) · Cerebrovascular Disorders (132) · Neuromuscular Diseases (96) · Mental Disorders (90) · Pathologic Processes (88) · Neurobehavioral Manifestations (87) · Neurodegenerative Diseases (69) · Neoplasms (57)
Sodium Chloride (22) · Saline Solution (17) · Dexmedetomidine (14) · Aspirin (12) · Botulinum Toxins, Type A (11) · Clopidogrel (10) · Dexamethasone (9) · Bupivacaine (7) · Lidocaine (7) · Magnesium Sulfate (7) · Melatonin (7) · Transcranial Direct Current Stimulation (7) · Atorvastatin (6) · Cilostazol (6) · Donepezil (6)
Kafrelsheikh University (11) · Apurano Pharmaceuticals GmbH (8) · Assiut University (8) · Capital Medical University (7) · All India Institute of Medical Sciences (6) · Beijing Tiantan Hospital (6) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (6) · National Taiwan University Hospital (6) · University of Calgary (6) · University of Toronto (6) · Chang Gung Memorial Hospital (5) · RenJi Hospital (5) · Samsung Medical Center (5) · Sun Yat-sen University (5) · Chinese Academy of Medical Sciences (4)
China (95) · United States (79) · Canada (50) · France (35) · Germany (34) · United Kingdom (31) · Brazil (28) · Egypt (27) · Italy (27) · Netherlands (23) · Spain (21) · India (16) · South Korea (16) · Taiwan (15) · Belgium (14)
Anna Taddio, PhD (5) · Gang Zhao, M.D. (3) · Oh Young Bang, MD (3) · Andrey S. Bryukhovetskiy, MD (2) · Ayman Tourbah, MD, PhD (2) · Franck Durif (2) · Frederic Sedel, MD, PhD (2) · Kaiming Liu, MD & PHD (2) · Mark Reisman, MD (2) · Mitchell Scheiman, OD (2) · Pong Ya-Ping, MD (2) · Rizaldy Pinzon, MD, MSc, PhD (2) · Rizaldy T Pinzon, MD, MSc, PhD (2)
PMID 18190818, PMID 31867054, PMID 2375765, PMID 11914403, PMID 12807523, PMID 22590713, PMID 23731663, PMID 24524844, PMID 25303679, PMID 25789053, PMID 30353868, PMID 30496104, PMID 30879893, PMID 32430657, PMID 33263359, PMID 38648030, PMID 8984084, PMID 10917410, PMID 10946168, PMID 11105983, PMID 11315017, PMID 11673584, PMID 12651674, PMID 12849360, PMID 12873949, PMID 12925241, PMID 1463007, PMID 15023839, PMID 15026214, PMID 1517644, PMID 15212606, PMID 15328899, PMID 15689584, PMID 15919269, PMID 16466610, PMID 16521220, PMID 1674640, PMID 16914460, PMID 17213237, PMID 17341537, PMID 17464603, PMID 17509235, PMID 17958887, PMID 17984407, PMID 18191686, PMID 18211362, PMID 18388680, PMID 18441370, PMID 18441371, PMID 18774912
2016 (3), 2017 (3), 2018 (3), 2014 (2), 2008 (1), 2015 (1), P01HD024448 (1), R01AG016381 (1), R01HD021453 (1), R01NR017850 (1), R01NS058302 (1), U10CA027469 (1), U10CA180868 (1), U10EY022599 (1)