796 unknown, 425 completed, 343 recruiting, 175 not yet recruiting. 716 Phase 2, 365 Not applicable, 321 Phase 3, 105 Phase 1, 78 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TEER In dynaMic sEvere Functional Mitral Regurgitation (TIMER) TEER, GDMT - Mitral Regurgitation Functional | Not applicable | Not yet recruiting | Sun Yat-sen University | 540 | 2027-01-01 | 2026-09-04 |
| Study on Improving Blood Glucose Homeostasis With Dorzagliatin Tablets in the Treatment of Type 2 Diabetes Mellitus Patients With Moderate to Severe Chronic Renal Insufficiency Dorzagliatin, Linagliptin - Type 2 Diabetes Mellitus (T2DM), Chronic Renal Insufficiency | Not applicable | Withdrawn | Sun Yat-sen University | 2026-12-01 | 2026-10-16 | |
| Efficacy and Safety of Tunlametinib Combination Therapy in the Treatment of Second-line and Above Metastatic Colorectal Cancer Arm1, Arm 2, Arm 3 - CRC (Colorectal Cancer), BRAF | Phase 2 | Not yet recruiting | Sun Yat-sen University | 91 | 2026-11-30 | 2026-07-21 |
| Becotatug Vedotin + Pucotenlimab+Platinum Induction and Sequential CCRT for Unresectable LA NSCLC Becotatug Vedotin (MRG003)+pucotenlimab+platinum, radiotherapy - Non-Small Cell Carcinoma of Lung, Locally Advanced | Phase 2 | Not yet recruiting | Sun Yat-sen University | 24 | 2026-11-15 | 2026-10-20 |
| Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer) Trilaciclib, Eribulin - Breast Cancer | Phase 2 | Not yet recruiting | Sun Yat-sen University | 29 | 2026-11-04 | 2025-12-01 |
| FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable Metastatic Colorectal Cancer (Phase II) Oxaliplatin, 5-Fluorouracil, Levofolinic Acid For Injection - Metastatic Colorectal Cancer (CRC) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 229 | 2026-11-01 | 2026-10-16 |
| Lenvatinib Plus Bevacizumab and PD-1 Inhibition Versus Bevacizumab Plus PD-1 Inhibition After Progression on Bevacizumab Plus Sintilimab in Unresectable Hepatocellular Carcinoma: A Prospective, Randomized, Two-Cohort, Phase II Study Intensified Treatment, Continued Treatment - Hepatocellulcar Carcinoma | Phase 2 | Not yet recruiting | Sun Yat-sen University | 100 | 2026-10-31 | 2026-10-13 |
| Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients Remimazolam group, Propofol group - Long-term Sedation for Mechanical Ventilation, Critically Ill Intensive Care Unit Patients | Phase 3 | Not yet recruiting | Sun Yat-sen University | 274 | 2026-10-20 | 2026-10-21 |
| Phase II Trial of Hypofractionated Radiotherapy Guided by Optical Surface Imaging and Fan-beam CT for Thymoma With Pleural Metastasis hypofractionated radiotherapy guided by optical surface imaging and FBCT, hypofractionated radiotherapy guided by CBCT - Thymoma and Thymic Carcinoma, Pleural Metastasis | Phase 2 | Not yet recruiting | Sun Yat-sen University | 234 | 2026-10-12 | 2026-10-16 |
| A Phase II Study of Anlotinib + PD-1 Inhibitor vs. PD-1 Inhibitor Maintenance After First-Line Chemoimmunotherapy in Advanced ESCC (Esophageal Squamous Cell Carcinoma) anlotinib + PD-1 inhibitor, PD-1 inhibitor - Esophageal Cancer (EC) | Phase 2 | Recruiting | Sun Yat-sen University | 112 | 2026-10-12 | 2026-10-07 |
| Prospective Phase II Study of Concurrent Radiotherapy Combined With Full-Course Immunotherapy or Consolidation Immunotherapy for Locally Advanced NSCLC Induction chemoimmunotherapy, radiotherapy, Concurrent Chemotherapy - Lung Cancer (NSCLC) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 256 | 2026-10-12 | 2026-10-14 |
| Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients MTM-Based AI Agent for smoking cessation, Counseling - Smoking Cessation, Early-Stage Cancer | Not applicable | Not yet recruiting | Sun Yat-sen University | 156 | 2026-10-01 | 2026-09-18 |
| mFOLFOXIRI Plus PD-1 Inhibitor vs mFOLFOX6 as Neoadjuvant Therapy for Locally Advanced Colon Cancer cmFOLFOXIRI plus PD-1 inhibitor, mFOLFOX6 - Colon Cancer (Stage II &Amp;Amp; III) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 138 | 2026-10-01 | 2026-05-22 |
| Cryoablation Combined With Hepatic Arterial Infusion of Iparomlimab and Tuvonralimab (QL1706), Intravenous Dacarbazine, and Oral Lenvatinib in Patients With Liver Metastases From Malignant Melanoma: a Single-arm, Phase II, Prospective Trial Cryoablation, Iparomlimab and Tuvonralimab, Dacarbazine - Melanoma (Skin) Stage IV | Phase 2 | Recruiting | Sun Yat-sen University | 28 | 2026-10-01 | 2026-09-29 |
| Local Ablation Plus Systemic Therapy for Metachronous Liver and/or Lung Oligometastases From Nasopharyngeal Carcinoma CT-guided percutaneous local ablation, Gemcitabine, Cisplatin - Nasopharyngeal Carcinoma, Neoplasm Metastasis | Phase 2 | Not yet recruiting | Sun Yat-sen University | 138 | 2026-10-01 | 2026-09-17 |
| ICF-Based Interdisciplinary Case Management for Individuals With Disabilities ICF-Based Interdisciplinary Case Management (Rehab-Cycle®), Conventional Care Management - Intellectual Disability, Mild to Moderate, Developmental Disability | Not applicable | Recruiting | The Hong Kong Polytechnic University | 120 | 2026-10-01 | 2026-09-10 |
| Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate in Transoral Surgery Intraoperative soft palate suspension using the double-strap method., Intraoperative soft palate suspension using the full-wrap method. - Adenoid Hypertrophy, Tonsillar Hypertrophy | Not applicable | Not yet recruiting | Sun Yat-sen University | 138 | 2026-09-30 | 2026-07-10 |
| Trastuzumab Rezetecan and Carboplatin ± Bevacizumab Versus Investigator's Choice Chemotherapy in Patients With Platinum-sensitive Recurrent Ovarian Cancer Trastuzumab Rezetecan (SHR-A1811), Carboplatin, Bevacizumab - Ovarian Cancer, Platinum Sensitive Ovarian Cancer (PSOC) | Phase 2 | Not yet recruiting | Sun Yat-sen University | 176 | 2026-09-30 | 2026-08-20 |
| Prophylactic Nanocrystalline Megestrol Acetate Versus Placebo for Chemoradiotherapy-Related Anorexia in Nasopharyngeal Carcinoma Nanocrystalline Megestrol Acetate Oral Suspension, Placebo - Nasopharyngeal Cancinoma (NPC) | Phase 3 | Recruiting | Sun Yat-sen University | 204 | 2026-09-29 | 2026-10-15 |
| Effects of Different PICC Catheterization Methods: A Multicenter Randomized Controlled Trial Conventional Non-Tunneled PICC catheterization, One-Needle Tunneled PICC catheterization, Two-Needle Tunneled PICC catheterization - Cancer Patients | Not applicable | Not yet recruiting | Sun Yat-sen University | 801 | 2026-09-10 | 2026-08-28 |
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Nasopharyngeal Carcinoma (190) · Carcinoma, Hepatocellular (177) · Carcinoma, Non-Small-Cell Lung (104) · Colorectal Neoplasms (90) · Breast Neoplasms (68) · Recurrence (39) · Nasopharyngeal Neoplasms (37) · Lung Neoplasms (36) · Rectal Neoplasms (36) · Esophageal Neoplasms (35) · Cataract (34) · Stomach Neoplasms (34) · Esophageal Squamous Cell Carcinoma (32) · Neoplasms (28) · Diabetes Mellitus, Type 2 (26)
Cisplatin (112) · Gemcitabine (67) · Fluorouracil (63) · Capecitabine (60) · Oxaliplatin (59) · toripalimab (59) · sintilimab (52) · Radiotherapy (50) · Bevacizumab (48) · Radiotherapy, Intensity-Modulated (45) · camrelizumab (42) · lenvatinib (41) · Drug Therapy (38) · Carboplatin (35) · Leucovorin (34)
China (1722) · Hong Kong (6) · India (1) · Israel (1) · Italy (1) · Singapore (1) · Taiwan (1) · United States (1)
Ming Shi, MD (21) · Hui Liu, Professor (20) · Jun Ma, M.D. (13) · Li Zhang, MD (12) · Wei Xia, PhD (11) · Ming-Yuan Chen, MD, PhD (10) · Yizhi Liu, M.D., Ph.D (10) · Yizhuo Zhang (10) · Feng Duan, MD (9) · Haotian Lin (8) · Haotian Lin, M.D., Ph.D (8) · Min Xia, PhD (8) · Ming-Yuan Chen, MD,PhD (8) · Weirong Chen, M.D. (8) · Yanhong Deng, M.D. (8)
PMID 31150573, PMID 12049862, PMID 33538338, PMID 25514302, PMID 27686945, PMID 28837405, PMID 34341578, PMID 11981766, PMID 12540794, PMID 25447852, PMID 25765670, PMID 29471013, PMID 29584545, PMID 30207593, PMID 34905388, PMID 35240053, PMID 35997729, PMID 36746459, PMID 36990609, PMID 15496622, PMID 16250051, PMID 16495695, PMID 18650514, PMID 20839057, PMID 21783417, PMID 22310081, PMID 23269991, PMID 23327199, PMID 24705333, PMID 25747273, PMID 26228759, PMID 26755520, PMID 26808342, PMID 27535056, PMID 27567279, PMID 28103904, PMID 30213452, PMID 30620929, PMID 31070690, PMID 31401903, PMID 32418078, PMID 33492986, PMID 34111416, PMID 34990291, PMID 35355438, PMID 35709465, PMID 35905860, PMID 36525610, PMID 36753281, PMID 37580352