373 completed, 120 recruiting, 104 unknown, 59 terminated. 246 Phase 2, 183 Not applicable, 135 Phase 1, 54 Phase 3, 13 Early Phase 1.
Follow Mouth Neoplasms: new trials by email Literature Review of Mouth Neoplasms trials Research Report on Mouth Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 9-ING-41 Plus Carboplatin in Patients With Advanced, Metastatic Salivary Gland Carcinoma 9-ING-41, Carboplatin - Salivary Gland Carcinoma, Adenoid Cystic Carcinoma | Phase 2 | Withdrawn | Actuate Therapeutics Inc. | 2030-12-18 | 2022-02-22 | |
| Risk Factors of Jaw Osteoradionecrosis in Oral Cavity Cancer Patients Post-Radiotherapy Osteoradionecrosis, Radiotherapy | Not yet recruiting | AO Innovation Translation Center | 1000 | 2027-03-01 | 2026-09-23 | |
| Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma Biospecimen Collection, Camonsertib, Computed Tomography - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 1 | Recruiting | National Cancer Institute (NCI) | 39 | 2027-02-13 | 2026-09-03 |
| Feasibility and Validation of an Automated AI-Enabled Deep Ultraviolet (DUV) Cytology Platform for Point-of-Care Oral Cancer Triage Deep UV-M and AI Cytology Triage - Oral Potentially Malignant Lesions, Oral Potentially Malignant Disorders | Not applicable | Not yet recruiting | Anh Le | 270 | 2026-12-01 | 2026-09-25 |
| Oral Cancer Awareness in Egypt Questionnaire - Oral Cancer | Not yet recruiting | Ayat Gamal-AbdelNaser | 1844 | 2026-12-01 | 2026-09-29 | |
| Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer SX-682, DTX - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 120 | 2026-10-27 | 2026-10-22 |
| Neoadjuvant Sintilimab Plus Chemotherapy for cT2N0M0 Oral Squamous Cell Carcinoma Sintilimab, Nab-Paclitaxel, Carboplatin - Oral Squamous Cell Carcinoma (OSCC), Head and Neck Squamous Cell Carcinoma | Phase 3 | Not yet recruiting | caohaotian | 300 | 2026-10-01 | 2026-09-18 |
| Abiraterone With Dalpiciclib in Salivary Gland Carcinoma abiraterone combined with dalpiciclib - Salivary Gland Carcinoma | Phase 2 | Recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 36 | 2026-10-01 | 2026-09-11 |
| Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Hypofractionated Stereotactic Body Radiotherapy (SBRT), Pembrolizumab, Ficerafusp alfa - Head and Neck Squamous Cell Carcinoma, HPV-Negative Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Washington University School of Medicine | 45 | 2026-09-30 | 2026-08-13 |
| Window Trial of Intratumoral (IT) Neoadjuvant Fluorescently Labelled Nivolumab (nivo800) in Head and Neck Squamous Cell Carcinoma (HNSCC) Nivolumab-IRDye800 - HNSCC, SCC - Squamous Cell Carcinoma | Early Phase 1 | Recruiting | Vanderbilt-Ingram Cancer Center | 18 | 2026-09-30 | 2026-10-19 |
| Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck Cancers Electronic Health Record Review, Fentanyl, Laryngoscopy - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Phase 4 | Recruiting | OHSU Knight Cancer Institute | 58 | 2026-09-22 | 2026-10-05 |
| Rehabilitation Through Individualized Support and Exercise Tailored physiotherapy program for early mobilization after oral cancer surgery - Oral Cancer, Head and Neck Cancer | Not applicable | Not yet recruiting | Universitaire Ziekenhuizen KU Leuven | 39 | 2026-09-10 | 2026-10-05 |
| Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions 5-Amino Levulinic Acid - Oral Cancer, Oral Cavity Cancer | Phase 2 | Not yet recruiting | University of Massachusetts, Boston | 65 | 2026-09-01 | 2026-03-19 |
| Thermotherapy for Head and Neck Cancer Patients Thermotherapy, Radiotherapy, Concurrent chemoradiation - Head and Neck Cancer, Oropharyngeal Carcinoma | Phase 1 | Recruiting | Erasmus Medical Center | 30 | 2026-09-01 | 2026-09-02 |
| Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer [64Cu]CM500, [68Ga]CM500, PET/MR - Bladder Cancer, Glioma | Early Phase 1 | Not yet recruiting | Lumina Pharmaceuticals Inc | 40 | 2026-09-01 | 2026-08-28 |
| Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients PERMA-H model mobile-based rehabilitation support program - Tracheostomized Patients, Decanulation | Not applicable | Not yet recruiting | Hainan Medical College | 100 | 2026-08-01 | 2026-07-20 |
| Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread Selective Neck Dissection (Levels I-IV), Modified Neck Dissection (Levels I-V) - Oral Cavity Squamous Cell Carcinoma | Not applicable | Recruiting | Kolhapur Cancer Centre - Cancer Centers of America | 80 | 2026-08-01 | 2026-08-04 |
| Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin Biospecimen Collection, Carboplatin, Cetuximab - Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 3 | Recruiting | NRG Oncology | 454 | 2026-07-31 | 2026-08-17 |
| A Feasibility Study of AI-Assisted Physiotherapy for Oral Cancer Patients AI-assisted physiotherapy - AI (Artificial Intelligence), Oral Cancer | Not applicable | Not yet recruiting | National Taiwan University Hospital | 15 | 2026-07-27 | 2026-07-20 |
| Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC) Nivo800, Nivolumab - Hnscc, Head and Neck | Phase 1 | Recruiting | Vanderbilt-Ingram Cancer Center | 40 | 2026-07-03 | 2026-10-16 |
Showing 20 of 773. Sign in to see all of them.
Squamous Cell Carcinoma of Head and Neck (273) · Head and Neck Neoplasms (255) · Salivary Gland Neoplasms (239) · Oropharyngeal Neoplasms (138) · Tongue Neoplasms (121) · Laryngeal Neoplasms (110) · Hypopharyngeal Neoplasms (93) · Carcinoma, Non-Small-Cell Lung (67) · Breast Neoplasms (66) · Esophageal Neoplasms (54) · Lung Neoplasms (51) · Pancreatic Neoplasms (51) · Nasopharyngeal Neoplasms (50) · Stomach Neoplasms (49)
Stomatognathic Diseases (772) · Neoplasms by Site (769) · Mouth Diseases (766) · Neoplasms (730) · Head and Neck Neoplasms (518) · Neoplasms by Histologic Type (373) · Neoplasms, Glandular and Epithelial (364) · Carcinoma (328) · Salivary Gland Diseases (268) · Carcinoma, Squamous Cell (253) · Otorhinolaryngologic Diseases (188) · Respiratory Tract Diseases (182) · Pharyngeal Diseases (177) · Otorhinolaryngologic Neoplasms (175)
Cisplatin (60) · Radiotherapy (37) · Cetuximab (33) · Magnetic Resonance Spectroscopy (29) · Radiotherapy, Intensity-Modulated (28) · pembrolizumab (27) · Docetaxel (26) · Carboplatin (25) · Biopsy (24) · Specimen Handling (22) · Paclitaxel (21) · Fluorouracil (17) · Radiation (17) · Erlotinib Hydrochloride (13) · Surgical Procedures, Operative (13)
National Cancer Institute (NCI) (73) · M.D. Anderson Cancer Center (28) · National Taiwan University Hospital (26) · Cairo University (16) · Memorial Sloan Kettering Cancer Center (14) · Vanderbilt-Ingram Cancer Center (14) · Roswell Park Cancer Institute (13) · Tata Memorial Hospital (9) · Dana-Farber Cancer Institute (8) · Mayo Clinic (8) · Chang Gung Memorial Hospital (7) · Eastern Cooperative Oncology Group (7) · Fox Chase Cancer Center (7) · Shanghai Jiao Tong University School of Medicine (7) · Alliance for Clinical Trials in Oncology (6)
United States (381) · China (47) · Canada (46) · France (45) · Taiwan (45) · India (30) · Egypt (28) · Italy (25) · United Kingdom (24) · Netherlands (20) · Germany (15) · Denmark (11) · Spain (10) · Belgium (9) · South Korea (9)
Barbara Murphy, MD (6) · Athanassios Argiris, MD (5) · Yueh-Hsia Chen, PhD (5) · Chun-Pin Chiang, DMSc (4) · Corey J. Langer, MD (3) · Glenn J Hanna, MD (3) · Hassan Arshad, MD (3) · Lai-ping Zhong, MD, PhD (3) · Shin-Jung Cheng, DDS, MS, PhD (3) · Yueh-Hsia Chen, Master (3) · Alan Ho, MD, PhD (2) · Alan L Ho (2) · Ann Gillenwater (2) · Ann M. Gillenwater, MD (2)
PMID 12361079, PMID 12988177, PMID 15172646, PMID 15979480, PMID 18457329, PMID 20014446, PMID 20623305, PMID 21541945, PMID 22108231, PMID 22422558, PMID 22864015, PMID 23720248, PMID 24817237, PMID 34503735, PMID 39532605, PMID 39584361, PMID 10071296, PMID 10772298, PMID 11754498, PMID 12625522, PMID 15459926, PMID 19260131, PMID 20299249, PMID 21537629, PMID 21794962, PMID 22947240, PMID 23358022, PMID 23431215, PMID 23996343, PMID 24478217, PMID 24658376, PMID 24909649, PMID 25057165, PMID 25224592, PMID 25229260, PMID 25613348, PMID 25931658, PMID 26027881, PMID 31838007, PMID 37650478, PMID 40086048, PMID 40341199, PMID 10459885, PMID 10646723, PMID 11246687, PMID 11246689, PMID 11308246, PMID 11784253, PMID 11841126, PMID 11914437
P30CA068485 (10), P30CA016672 (8), U10CA180868 (8), P30CA006516 (6), P30CA023074 (5), U10CA180820 (5), U10CA021115 (4), U10CA031946 (4), U10CA032102 (4), 2015 (3), N01CM62201 (3), P30CA006927 (3), P30CA014520 (3), P30CA014599 (3), P30CA043703 (3)