55 terminated. 55 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 55 | Terminated 55 |
Follow Mood Disorders: new trials by email Literature Review of Mood Disorders trials Research Report on Mood Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Levodopa and Exercise for Older Adults With Depression and Psychomotor Slowing Carbidopa/levodopa, Placebo, Exercise training - Depressive Disorder | Phase 4 | Terminated | New York State Psychiatric Institute | 1 | 2021-10-07 | 2023-02-02 |
| Antidepressant Response in Older Adults With Comorbid PTSD and MDD Escitalopram, Duloxetine - Post Traumatic Stress Disorder, Major Depressive Disorder | Phase 4 | Terminated | New York State Psychiatric Institute | 1 | 2021-03-03 | 2022-05-11 |
| Tianeptine for Treatment Resistant Depression Tianeptine Sodium - Treatment Resistant Depression | Phase 4 | Terminated | Jonathan A. Javitch, MD, PhD | 38 | 2020-10-14 | 2026-01-23 |
| Predicting SSRI Efficacy in Veterans With PTSD LDAEP, Placebo, sertraline - Posttraumatic Stress Disorder, Major Depressive Disorder | Phase 4 | Terminated | VA Office of Research and Development | 19 | 2019-09-11 | 2026-06-17 |
| Promoting Enhanced Pharmacotherapy Choice Through Immunomarkers Evaluation in Depression Escitalopram, Bupropion - Depression | Phase 4 | Terminated | University of Texas Southwestern Medical Center | 18 | 2019-07-23 | 2023-04-18 |
| L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults L-DOPA, Placebo Oral Tablet - Major Depressive Disorder, Dysthymia | Phase 4 | Terminated | New York State Psychiatric Institute | 51 | 2019-01-09 | 2023-05-22 |
| A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder Abilify MyCite - Digital Medicine System, Aripiprazole or other oral antipsychotics - Schizophrenia, Bipolar 1 Disorder | Phase 4 | Terminated | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2 | 2018-06-28 | 2019-11-08 |
| Combinatorial Pharmacogenomics Testing in Treatment-Naïve Major Depressive Disorder GeneSight Psychotropic test, FDA-approved antidepressant or antipsychotic treatment - Major Depressive Disorder, Depression | Phase 4 | Terminated | Washington University School of Medicine | 6 | 2018-05-04 | 2020-06-05 |
| Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial Metformin, Vitamin D - PCOS, Depression | Phase 4 | Terminated | University of California, San Francisco | 5 | 2017-12-12 | 2021-02-09 |
| Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine Vortioxetine - Depressive Disorder, Major Depression | Phase 4 | Terminated | Massachusetts General Hospital | 2 | 2017-08-24 | 2019-10-14 |
| SALT Study (Switching to the Administration of Lithium Slow -Release Treatment) Lithium sulphate prolonged-release 660 mg, Lithium carbonate immediate-release 150 mg and 300 mg - Bipolar Disorder | Phase 4 | Terminated | Aziende Chimiche Riunite Angelini Francesco S.p.A | 85 | 2017-03-28 | 2020-01-10 |
| Escitalopram Plus PS128 vs. Escitalopram Lactobacillus plantarum PS128 - Major Depression | Phase 4 | Terminated | Kaohsiung Kai-Suan Psychiatric Hospital | 41 | 2016-11-18 | 2019-09-18 |
| Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females 5-hydroxytryptophan and Creatine, Placebo control - Major Depressive Disorder | Phase 4 | Terminated | Brent Michael Kious, MD, PhD | 32 | 2016-11-01 | 2022-05-31 |
| DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder Carbamazepine, Placebo - Bipolar Disorder | Phase 4 | Terminated | Validus Pharmaceuticals | 17 | 2016-10-24 | 2023-03-03 |
| Gao NARASD Lithium Study Lithium - Bipolar Disorder | Phase 4 | Terminated | Keming Gao | 24 | 2016-09-01 | 2020-07-10 |
| Bupropion for Depression in ESRD Patients on Hemodialysis Fluoxetine, Bupropion - Major Depression, End Stage Renal Disease | Phase 4 | Terminated | University of Arkansas | 1 | 2016-03-31 | 2018-07-17 |
| 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression Lamotrigine, Fluoxetine - Bipolar Disorder | Phase 4 | Terminated | Mayo Clinic | 2 | 2015-03-01 | 2019-06-19 |
| Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life Depression Sertraline, Candesartan - Depression, Hypertension | Phase 4 | Terminated | Vanderbilt University | 1 | 2013-05-01 | 2016-10-20 |
| Does Vilazodone Help With Antidepressant-associated Sexual Dysfunction? Vilazodone, Sertraline - Sexual Dysfunction, Major Depressive Disorder | Phase 4 | Terminated | Thomas Jefferson University | 4 | 2013-01-01 | 2016-08-25 |
| Neurobiological Bases of Placebo Response in Major Depressive Disorder Escitalopram 10mg, Placebo - Major Depressive Disorder | Phase 4 | Terminated | Massachusetts General Hospital | 20 | 2012-11-01 | 2017-05-16 |
Showing 20 of 55. Sign in to see all of them.
Depressive Disorder, Major (26) · Bipolar Disorder (23) · Depression (18) · Depressive Disorder (5) · Depressive Disorder, Treatment-Resistant (3) · Anxiety Disorders (2) · Dysthymic Disorder (2) · Generalized Anxiety Disorder (2) · Insulin Resistance (2) · Mania (2) · Obsessive-Compulsive Disorder (2) · Stress Disorders, Post-Traumatic (2) · Agoraphobia (1) · Alcoholism (1)
Mental Disorders (55) · Depressive Disorder (26) · Bipolar and Related Disorders (23) · Behavior (18) · Behavioral Symptoms (18) · Nervous System Diseases (5) · Pathological Conditions, Signs and Symptoms (4) · Anxiety Disorders (3) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Urogenital Diseases (3) · Brain Diseases (2) · Cardiovascular Diseases (2) · Central Nervous System Diseases (2)
Escitalopram (7) · Bupropion (5) · Sertraline (5) · Fluoxetine (4) · Aripiprazole (3) · Olanzapine (3) · Paroxetine (3) · Quetiapine Fumarate (3) · Creatine (2) · Ketamine (2) · Lamotrigine (2) · Lithium (2) · Sugars (2) · Tranylcypromine (2) · Valproic Acid (2)
Massachusetts General Hospital (9) · New York State Psychiatric Institute (8) · University Hospitals Cleveland Medical Center (2) · Weill Medical College of Cornell University (2) · Abbott (1) · AstraZeneca (1) · Aziende Chimiche Riunite Angelini Francesco S.p.A (1) · Brent Michael Kious, MD, PhD (1) · Cedars-Sinai Medical Center (1) · Elan Pharmaceuticals (1) · Eli Lilly and Company (1) · Emory University (1) · GlaxoSmithKline (1) · Hamilton Health Sciences Corporation (1) · Herzog Hospital (1)
United States (42) · Denmark (2) · Italy (2) · Canada (1) · Germany (1) · Greece (1) · Israel (1) · Japan (1) · Norway (1) · South Korea (1) · Spain (1) · Sweden (1) · Taiwan (1) · Turkey (Türkiye) (1)
Bret R Rutherford, MD (2) · Janet Wozniak, MD (2) · Keming Gao, MD, PhD (2) · Alla Landa, PhD (1) · Andrew Nierenberg, M.D. (1) · Anita Clayton, MD (1) · Boris Nemets, Dr. (1) · Bret Rutherford, MD (1) · Bruce Cohen, MD, PhD (1) · Charles Conway, MD (1) · Cristina Cusin, M.D. (1) · David Kemp, MD (1) · Deborah Deliyannides, M.D. (1)
PMID 21993207, PMID 22283499, PMID 24107760, PMID 24972362, PMID 26529118, PMID 30699881, PMID 39626074
2016 (1), K23MH067710 (1), K23MH076049 (1), K24MH122514 (1), P20AA015630 (1), R21DK097470 (1), R33MH110029 (1), RC1MH088405-01 (1), UL1TR000135 (1)