1021 completed, 210 recruiting, 150 unknown, 83 terminated. 758 Not applicable, 383 Phase 2, 135 Phase 1, 125 Phase 4, 124 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease AcamproSync - Alcohol Use Disorder, Alcohol Associated Liver Disease | Not applicable | Not yet recruiting | Yale University | 50 | 2027-10-01 | 2026-04-28 |
| Self-administered Neurostimulation Intervention for Firefighter Traumatic Stress to Reduce Alcohol Use: Pilot Study Transcutaneous auricular neurostimulation (tAN), Active Sham - Posttraumatic Stress Symptoms, Heavy Alcoholic Consumption | Not applicable | Not yet recruiting | University of Cincinnati | 20 | 2027-09-01 | 2026-10-09 |
| eTSF for Latinx Young Adults With Alcohol Use Disorder eTSF, Educational materials - Alcohol Use Disorder (AUD) | Not applicable | Not yet recruiting | Tulane University | 40 | 2027-08-01 | 2026-10-13 |
| Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania IDEAS-AUD - Alcohol Use Disorder, Suicide Prevention | Not applicable | Not yet recruiting | Duke University | 30 | 2027-08-01 | 2026-03-17 |
| A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults Large language model-based chatbot brief alcohol intervention session - Alcohol Use Disorder | Not applicable | Not yet recruiting | Massachusetts General Hospital | 20 | 2027-06-01 | 2025-10-22 |
| TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD) TMS Low-Dose, TMS High-Dose - Alcohol Use Disorder, Opioid Use Disorder | Not applicable | Recruiting | Washington State University | 60 | 2027-06-01 | 2026-05-29 |
| Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making. CBT4CBT - Alcohol Use Disorder (AUD), Suicidal Ideation | Not applicable | Not yet recruiting | Mark J Rzeszutek, PhD | 180 | 2027-03-01 | 2026-09-25 |
| Preventing Harmful Alcohol Use Among Trauma Patients in Cameroon Cameroon-Adapted SBIRT, Usual Care - Alcohol Use Disorder, Alcohol-Related Injury | Not applicable | Not yet recruiting | University of Buea | 690 | 2027-03-01 | 2026-06-30 |
| PTSD and Alcohol Couples Treatment for Veterans COPE + BFIT - PTSD, AUD | Early Phase 1 | Not yet recruiting | VA Office of Research and Development | 80 | 2027-03-01 | 2026-02-10 |
| Intervention for Alcohol Use Disorder Recovery After Liver Transplantation Online Sober Active Community, Recovery coach - Liver Transplant Recipient, Alcohol Use Disorders (AUD) | Not applicable | Not yet recruiting | Leigh Anne Dageforde | 40 | 2027-03-01 | 2026-07-20 |
| Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda. Kisoboka Amaka, Screening and Referral - HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption | Not applicable | Not yet recruiting | San Diego State University | 60 | 2027-02-01 | 2026-06-22 |
| Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior CLT- Concrete text messages, CLT- Abstract text messages, Control messages - HIV, Risk Behavior | Not applicable | Not yet recruiting | Emory University | 240 | 2027-02-01 | 2026-08-19 |
| Pregnenolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding Study Brexanolone - Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD) | Phase 2 | Not yet recruiting | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | 40 | 2027-01-15 | 2026-09-21 |
| Daridorexant for Alcohol Use Disorder Daridorexant 50 mg, Placebo - Alcohol Use Disorder | Phase 2 | Not yet recruiting | Johns Hopkins University | 150 | 2027-01-01 | 2026-04-20 |
| Pomegranate Dietary Supplements in AUD and ALD Pomegranate Dietary Ssupplement - Alcohol Use Disorder, Alcohol-associated Liver Disease | Not yet recruiting | University of Louisville | 144 | 2027-01-01 | 2026-07-24 | |
| A Study of the Effect of a Nurse Navigator Program on High Risk Patients Nurse Navigator Program - Patient Readmission, Arthroplasty, Replacement, Knee | Not applicable | Not yet recruiting | Mayo Clinic | 300 | 2027-01-01 | 2026-03-19 |
| Testing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery (CalmiFy II) Stress Feedback, Music Listening - Alcohol Use Disorder (AUD) | Not applicable | Not yet recruiting | Washington State University | 30 | 2026-12-01 | 2026-05-05 |
| Disease Intervention Specialist (DIS) for SUD Substance Use Disorder (SUD), Opioid Use Disorder | Not yet recruiting | Ohio State University | 1200 | 2026-12-01 | 2026-10-15 | |
| Effectiveness of Nurse-Conducted Brief Intervention (NCBI) Supplemented With Mobile for Preventing Alcohol Use Disorders Nurse-Conducted Brief Intervention (NCBI). supplemented with mobile based application., Nurse-Conducted Brief Intervention (NCBI) - Alcohol Use Disorder (AUD) | Not applicable | Not yet recruiting | University of Pittsburgh | 74 | 2026-12-01 | 2026-06-05 |
| Alpha Down Electroencephalography (EEG) Neurofeedback for Alcohol Use Disorder: Feasibility Trial EEG Neurofeedback - Alcohol Use Disorder (AUD) | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 10 | 2026-12-01 | 2026-10-01 |
Showing 20 of 1666. Sign in to see all of them.
Substance-Related Disorders (206) · Alcohol Drinking (150) · Stress Disorders, Post-Traumatic (98) · Depression (81) · Behavior, Addictive (76) · Anxiety Disorders (73) · Alcohol-Related Disorders (69) · Opioid-Related Disorders (35) · Tobacco Use Disorder (35) · Bipolar Disorder (31) · Recurrence (31) · Depressive Disorder, Major (28) · Mental Disorders (27) · Smoking (27)
Chemically-Induced Disorders (1660) · Mental Disorders (1639) · Alcohol-Related Disorders (1597) · Substance-Related Disorders (1460) · Behavior (428) · Drinking Behavior (160) · Pathological Conditions, Signs and Symptoms (143) · Trauma and Stressor Related Disorders (105) · Behavioral Symptoms (104) · Stress Disorders, Traumatic (101) · Pathologic Processes (96) · Compulsive Behavior (76) · Impulsive Behavior (74) · Nervous System Diseases (67) · Mood Disorders (62)
Ethanol (142) · Naltrexone (98) · Sugars (44) · Cognitive Behavioral Therapy (39) · Motivational Interviewing (36) · Therapeutics (31) · Crisis Intervention (29) · Topiramate (28) · Acamprosate (27) · vivitrol (23) · Baclofen (19) · Psilocybin (19) · Methods (18) · Varenicline (17) · Ondansetron (14)
Yale University (91) · National Institute on Alcohol Abuse and Alcoholism (NIAAA) (70) · VA Office of Research and Development (47) · Medical University of South Carolina (43) · Brown University (31) · University of Pennsylvania (28) · Centre for Addiction and Mental Health (22) · UConn Health (21) · University of California, San Francisco (20) · University of California, Los Angeles (19) · New York State Psychiatric Institute (18) · University of Washington (18) · Central Institute of Mental Health, Mannheim (17) · University of North Carolina, Chapel Hill (17) · University of Colorado, Denver (16)
United States (1068) · France (94) · Germany (66) · Canada (40) · United Kingdom (33) · Denmark (29) · Sweden (29) · Spain (25) · China (23) · Belgium (18) · Australia (17) · Switzerland (12) · Norway (11) · Netherlands (10) · Turkey (Türkiye) (10)
Lorenzo Leggio, M.D. (10) · Lara Ray, PhD (9) · Ismene Petrakis, M.D. (7) · Anne H Berman, PhD (6) · Barbara J. Mason, Ph.D. (6) · Ismene L Petrakis, MD (6) · John R Knight, MD (6) · Raymond F Anton, MD (6) · David W. Oslin, MD (5) · Gihyun Yoon, MD (5) · Nancy Diazgranados, M.D. (5) · Rajita Sinha, PhD (5) · Steven L Batki, MD (5)
PMID 37795783, PMID 25227627, PMID 30865232, PMID 15811981, PMID 17663609, PMID 19309183, PMID 20732631, PMID 23873853, PMID 24190578, PMID 25832297, PMID 29461925, PMID 29575339, PMID 33012365, PMID 33410985, PMID 33605440, PMID 35285015, PMID 35858989, PMID 36001430, PMID 37142273, PMID 37146499, PMID 37230961, PMID 37897693, PMID 38419905, PMID 40483726, PMID 41329966, PMID 10553740, PMID 10628520, PMID 10891633, PMID 11153967, PMID 11468137, PMID 11493907, PMID 11496122, PMID 11707638, PMID 12507797, PMID 12589885, PMID 12637048, PMID 12748029, PMID 1334156, PMID 1345133, PMID 1444726, PMID 14645769, PMID 15630071, PMID 15834219, PMID 15850502, PMID 15908848, PMID 15956269, PMID 16009352, PMID 16012278, PMID 16129568, PMID 16240558
P50AA010761 (6), P50AA012870 (6), 2015 (5), 2023 (5), 2025 (5), P50DA012756 (5), P60AA003510 (5), P60AA013759 (5), U54AA027989 (5), P60AA007611 (4), P01AA029545 (3), P50AA003510 (3), P60DA005186 (3), R01AA011197 (3), R01AA012602 (3)