372 completed, 112 recruiting, 88 unknown, 35 terminated. 405 Not applicable, 113 Phase 2, 40 Phase 4, 36 Phase 1, 34 Phase 3.
Follow Obsessive-Compulsive Disorder: new trials by email Literature Review of Obsessive-Compulsive Disorder trials Research Report on Obsessive-Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neurobehavioral Investigations of Approach Dynamics in the Ventral Striatum Medtronic Percept RC neurostimulator - Obsessive-Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Baylor College of Medicine | 12 | 2027-08-01 | 2026-10-01 |
| Locating Biomarkers in OCD Through Behavioral Tasks Beads Task, PROVOC Tasks - OCD, Obsessive-Compulsive Disorder | Not yet recruiting | Baylor College of Medicine | 20 | 2027-03-01 | 2026-06-30 | |
| A Digital Mindfulness-Based Program for OCD Mindfulness-based cognitive-behavioral therapy digital program - Obsessive-Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Unidade Local de Saúde de Coimbra, EPE | 128 | 2027-03-01 | 2026-10-13 |
| Low-intensity Ultrasound for Individuals With Obsessive-compulsive Disorder Low-intensity focused ultrasound (Active), Low-intensity focused ultrasound (Sham) - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | University of Calgary | 20 | 2026-11-01 | 2026-10-14 |
| Precision Brain Mapping to Predict and Track Response to Exposure and Response Prevention Therapy in Youth With Obsessive-Compulsive Disorder Exposure and Response Prevention Therapy, Clinical Assessments, Research MRI Sessions - Obsessive-Compulsive Disorder | Not applicable | Withdrawn | Weill Medical College of Cornell University | 2026-11-01 | 2026-08-05 | |
| Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder Medtronic Percept Deep Brain Stimulation Therapy [Sham Control Stimulation], Medtronic Percept Deep Brain Stimulation Therapy [Therapeutic stimulation] - Obsessive-Compulsive Disorder | Not applicable | Recruiting | Nader Pouratian | 10 | 2026-11-01 | 2026-10-01 |
| Feasibility of Modulating Cognitive Control in OCD continuous theta-burst transcranial magnetic stimulation (cTBS) - Obsessive-Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Dartmouth-Hitchcock Medical Center | 12 | 2026-11-01 | 2026-10-02 |
| Focused Ultrasound for Behavioral Health ATTN201 head-worn focused ultrasound - Depression, Anxiety | Not applicable | Recruiting | Attune Neurosciences Inc | 300 | 2026-10-19 | 2026-10-27 |
| Artificial Intelligence-Powered Virtual Reality Exposure Therapy for OCD in College Students: A Proof-of-Concept Study Traditional Exposure and Response Prevention (ERP), Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET) - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | University of California, San Diego | 24 | 2026-10-01 | 2026-10-16 |
| A Test of Acceptance-based Bibliotherapy for Hoarding Disorder Acceptance and Commitment Therapy Bibliotherapy - Hoarding Disorder | Not applicable | Not yet recruiting | Utah State University | 60 | 2026-10-01 | 2026-10-19 |
| Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD) ADHD, Obsessive Compulsive Disorder (OCD) | Recruiting | National Institute of Mental Health (NIMH) | 110 | 2026-09-30 | 2026-10-05 | |
| Cohort Study of Obsessive-Compulsive Disorder Obsessive - Compulsive Disorder | Not yet recruiting | Shanghai Mental Health Center | 500 | 2026-09-15 | 2026-09-16 | |
| Psilocybin for Treatment of OCD-2 Low Dose Psilocybin, High Dose Psilocybin - Obsessive - Compulsive Disorder | Phase 1 / Phase 2 | Not yet recruiting | Francisco A Moreno | 20 | 2026-09-08 | 2026-05-12 |
| Transcutaneous Electrical Acupoint Stimulation Combined With Exposure and Response Prevention in the Treatment of Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial Exposure and Response Prevention, Active Transcutaneous Acupoint Electrical Stimulation, Sham Transcutaneous Acupoint Electrical Stimulation - Obsessive Compulsive Disorder (OCD) | Not applicable | Not yet recruiting | Shanghai Mental Health Center | 90 | 2026-09-07 | 2026-09-10 |
| Non-Coding RNAs Gene Expression in Psychiatric Disorders Reverse Transcription Quantitative Polymerase Chain Reaction - Schizophrenia Disorders, Major Depression | Not yet recruiting | Carmen Concerto | 384 | 2026-09-01 | 2026-06-23 | |
| Clinical and Biological Correlates of Obsessive-Compulsive Disorder and Online Mindfulness-Based Cognitive Therapy Mindfulness-based Cognitive Therapy for OCD - Obsessive - Compulsive Disorder | Not applicable | Recruiting | IRCCS Centro San Giovanni di Dio Fatebenefratelli | 42 | 2026-08-26 | 2026-09-25 |
| Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales - Schizophrenia, Treatment Resistant Depression (TRD) | Not applicable | Recruiting | Centre Hospitalier St Anne | 700 | 2026-08-20 | 2026-09-21 |
| Sonication-based OCD Neurosurgical Intervention Via Capsulotomy ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy - Obsessive-Compulsive Disorder | Phase 1 / Phase 2 | Not yet recruiting | Brigham and Women's Hospital | 66 | 2026-08-01 | 2026-02-25 |
| Digital Mindfulness-Based Therapy for Obsessive-Compulsive Disorder Digital Mindfulness-Based Therapy, Routine Pharmacological Treatment - Obsessive-Compulsive Disorder | Not applicable | Recruiting | Central South University | 150 | 2026-07-15 | 2026-07-20 |
| Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD) Exposure and Response Prevention (ERP), Habit Reversal Training (HbRT, Psychoeducation and Supportive Intervention - Obsessive - Compulsive Disorder, Tic Disorder, Chronic Motor or Vocal | Not applicable | Recruiting | University College London Hospitals | 40 | 2026-07-08 | 2026-07-27 |
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Anxiety Disorders (97) · Generalized Anxiety Disorder (53) · Trichotillomania (48) · Phobia, Social (43) · Stress Disorders, Post-Traumatic (33) · Hoarding Disorder (32) · Panic Disorder (32) · Depression (31) · Depressive Disorder, Major (27) · Mental Disorders (24) · Compulsive Personality Disorder (20) · Excoriation Disorder (20) · Anxiety, Separation (19) · Tourette Syndrome (18)
Mental Disorders (679) · Anxiety Disorders (606) · Behavior (105) · Behavioral Symptoms (63) · Nervous System Diseases (56) · Neurodevelopmental Disorders (56) · Disruptive, Impulse Control, and Conduct Disorders (54) · Pathological Conditions, Signs and Symptoms (51) · Signs and Symptoms (46) · Phobic Disorders (40) · Mood Disorders (39) · Trauma and Stressor Related Disorders (37) · Central Nervous System Diseases (36) · Stress Disorders, Traumatic (35)
Cognitive Behavioral Therapy (56) · Transcranial Magnetic Stimulation (27) · Deep Brain Stimulation (26) · Therapeutics (18) · Behavior Therapy (14) · Fluoxetine (13) · Ketamine (13) · Sertraline (12) · Cycloserine (11) · Fluvoxamine (10) · Psychotherapy (10) · Transcranial Direct Current Stimulation (10) · Escitalopram (8) · Implosive Therapy (8) · Paroxetine (8)
New York State Psychiatric Institute (27) · Massachusetts General Hospital (26) · Shanghai Mental Health Center (26) · Karolinska Institutet (20) · Stanford University (18) · University of South Florida (17) · Baylor College of Medicine (16) · National Institute of Mental Health (NIMH) (16) · University of Chicago (16) · Yale University (15) · Sunnybrook Health Sciences Centre (13) · Butler Hospital (11) · University of California, Los Angeles (9) · Mclean Hospital (8) · Sheba Medical Center (8)
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Jon E Grant, MD, JD, MPH (7) · Joseph Zohar, MD (7) · Wayne Goodman, MD (7) · Zhen Wang, PhD,MD (7) · Carolyn I Rodriguez, MD, PhD (5) · Eric Storch, Ph.D. (5) · Michael Van Ameringen, MD, FRCPC (5) · Eric A Storch, Ph.D. (4) · S. Evelyn Stewart, MD (4) · Bomin Sun, MD, PhD (3) · Carolyn I. Rodriguez, M.D., Ph.D. (3) · Carolyn Rodriguez, MD, PhD (3) · Darin D Dougherty, MD (3) · Eric Hollander, MD (3) · H Blair Simpson, MD, PhD (3)
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1UH3NS100549 (3), 2019 (3), R01MH045436 (3), 2005 (2), 2023 (2), K23MH092434 (2), P30MH066386 (2), R34MH095885 (2), R34MH100468 (2), 2009 (1), 2018 (1), 2025 (1), F32MH129076 (1), K23MH071754 (1), K23MH111977 (1)