570 completed, 113 terminated, 48 unknown, 42 withdrawn. 276 Phase 2, 178 Not applicable, 175 Phase 4, 149 Phase 3, 71 Phase 1.
Follow Sugars: new trials by email Literature Review of Sugars trials Research Report on Sugars
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Crossover Study Evaluating the Postprandial Glycemic Response of Three Sweeteners in a Mixed Meal Setting LOAM Fiber-based Sweetener, Sugar, Stevia - Postprandial Glucose, GI Tolerance | Not applicable | Not yet recruiting | LOAM Science | 50 | 2026-12-01 | 2026-10-26 |
| Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy Clemastine Fumarate, Placebo - Demyelinating Diseases, Demyelination; Corpus Callosum | Phase 1 / Phase 2 | Not yet recruiting | University of California, San Francisco | 44 | 2026-09-15 | 2026-03-11 |
| Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids 2 mL SunButyrate-TG, Placebo, 4 mL SunButyrate-TG - Congenital Heart Disease (CHD) | Phase 1 / Phase 2 | Not yet recruiting | University of Nebraska | 105 | 2026-03-01 | 2026-02-24 |
| Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty Sleeping Eszopiclone 3 mg, Placebo, Lemborexant 10mg - OSA - Obstructive Sleep Apnea | Phase 2 | Recruiting | Flinders University | 15 | 2025-10-31 | 2026-09-02 |
| Evaluating the Impact of Fat and Sugar Replacer Blends on Gastrointestinal Tolerance in Biscuits Test sandwiched biscuits with creme, Control sandwiched biscuit with sugar - Gastrointestinal Tolerance, Healthy Population | Not applicable | Completed | Mondelēz International, Inc. | 56 | 2025-10-28 | 2026-03-27 |
| JAK Signaling in Depression Baricitinib, Placebo - Major Depressive Disorder | Phase 2 | Recruiting | Emory University | 100 | 2025-09-03 | 2026-09-28 |
| Modafinil and Exercise for Post Stroke Fatigue Modafinil 200mg, Placebo, Exercise - Stroke, Fatigue | Phase 3 | Not yet recruiting | University Health Network, Toronto | 212 | 2025-09-01 | 2025-06-10 |
| The Role of Vitamin K on Knee Osteoarthritis Outcomes Vitamin K1 500 µg, K1 1000 µg, Vitamin K2 (MK-7) 300 µg - Osteo Arthritis Knee | Phase 1 / Phase 2 | Active not recruiting | Boston University | 49 | 2025-06-03 | 2026-09-21 |
| Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults AGB101, Placebo - Hippocampal Overactivity, Dementia | Phase 2 | Active not recruiting | Johns Hopkins University | 60 | 2025-04-17 | 2026-08-31 |
| Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Placebo-controlled Trial Bacillus clausii, Sugar tablets - Ventilator Acquired Pneumonia, Catheter Related Bloodstream Infection | Not applicable | Enrolling by invitation | Benha University | 100 | 2025-04-01 | 2025-09-10 |
| Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) Cyclobenzaprine HCl, Placebo - Acute Stress Reaction, Acute Stress Disorder | Phase 2 | Recruiting | University of North Carolina, Chapel Hill | 180 | 2025-03-25 | 2026-10-22 |
| GRAPE-GDM Prospective Comperative Trial - Grape Juice as a Replacement Drink for Gestational Diabetes Screening Participants will consume 500 ml of commercially available grape juice which contains 50g of sugar, serving as an alternative glucose load. - Pregnancy - Prenatal Testing | Not applicable | Enrolling by invitation | Bnai Zion Medical Center | 150 | 2025-02-19 | 2026-01-07 |
| A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer Relacorilant, Enzalutamide, Placebo (Sugar Pill) - Prostate Cancer, Prostate Adenocarcinoma | Phase 2 | Recruiting | University of Chicago | 90 | 2025-01-06 | 2026-08-31 |
| PNF Versus Cryotherapy in Delayed Onset Muscle Soreness Proprioceptive Neuromuscular Facilitation, Local Cryotherapy, Placebo: Water With Sugar - Delayed Onset Muscle Soreness (DOMS) | Not applicable | Completed | Universidad Pontificia de Salamanca | 29 | 2025-01-01 | 2026-06-16 |
| Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols Dexamethasone, Placebo - Rhabdomyolysis | Phase 1 | Recruiting | Children's National Research Institute | 50 | 2024-10-01 | 2025-07-03 |
| Efficacy of Recombinant Bovine Lactoferrin (rbLf) in Iron Regulation Recombinant Bovine Lactoferrin, Bovine Milk-Derived Lactoferrin, Placebo - Exercise Performance | Not applicable | Completed | University of North Carolina, Chapel Hill | 92 | 2024-07-05 | 2025-09-17 |
| Reducing Salt and Sugar in Campus Foods: A Malaysian Study Reduction in Salt and Sugar, The potentiometer, Dry Ashing Method Followed by Flame Atomic Absorption Spectrometry (FAAS) - Cardiovascular Diseases | Not applicable | Not yet recruiting | Sunway University | 300 | 2024-07-01 | 2024-06-25 |
| Role Of Sensitivity to neuroEndocrine Systems in Social Decisions Hydrocortisone, Yohimbine, Placebo - Borderline Personality Disorder | Phase 4 | Withdrawn | University of North Carolina, Chapel Hill | 2024-07-01 | 2024-06-05 | |
| Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis open-label placebo, Treatment as usual - Adolescent Idiopathic Scoliosis (AIS) | Not applicable | Recruiting | University of California, San Francisco | 64 | 2024-07-01 | 2026-03-13 |
| An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian Cancer Statin, Sugar pill - Ovarian Cancer | Phase 2 | Unknown | Anhui Provincial Cancer Hospital | 500 | 2024-06-30 | 2024-06-21 |
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PMID 37142273, PMID 34611902, PMID 21849262, PMID 24045678, PMID 24552977, PMID 25137243, PMID 29065885, PMID 29444682, PMID 34229290, PMID 34433773, PMID 36130734, PMID 36269595, PMID 36999619, PMID 37230961, PMID 10598635, PMID 10816186, PMID 12112073, PMID 12670812, PMID 15275765, PMID 15692967, PMID 16324089, PMID 16414336, PMID 16679671, PMID 16790698, PMID 17194267, PMID 17251278, PMID 17469162, PMID 17485423, PMID 17668979, PMID 17716312, PMID 17716313, PMID 17717203, PMID 17901414, PMID 18174456, PMID 18251624, PMID 18641099, PMID 18672990, PMID 18700421, PMID 19023036, PMID 19155011, PMID 19167733, PMID 19489872, PMID 19577749, PMID 19693492, PMID 19776222, PMID 19892673, PMID 19910321, PMID 20092966, PMID 20151804, PMID 20155590
P50DA018197 (5), 2009 (3), P50DA018185 (3), R01AA012602 (3), R01CA026582 (3), R01DA014537 (3), 2008 (2), 2015 (2), K01AA026005 (2), P01HL095491 (2), R01AA010522 (2), R01AT007987 (2), R01DA021264 (2), R01DA027134 (2), R01DA036564 (2)