31 completed, 5 recruiting, 3 terminated, 2 active not recruiting. 13 Phase 1, 6 Phase 2, 5 Phase 4, 3 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 13 | Completed 13 |
| Phase 2 | 6 | Completed 6 |
| Phase 4 | 5 | Completed 3, Terminated 2 |
| Not applicable | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cenobamate Efficacy in Individuals With Autoimmune Epilepsy Autoimmune Epilepsy | Enrolling by invitation | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 30 | 2026-02-01 | 2026-03-16 | |
| Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder Radiprodil, Placebo - GRIN-related Neurodevelopmental Disorder | Phase 3 | Recruiting | GRIN Therapeutics, Inc. | 100 | 2026-01-05 | 2026-07-17 |
| Real-world Clinical Response to Trazodone in Italy, Poland, and Romania Depression - Major Depressive Disorder, Cognition Disorders in Old Age | Recruiting | Aziende Chimiche Riunite Angelini Francesco S.p.A | 120 | 2025-12-15 | 2026-01-30 | |
| Palatability Study of Five Formulations of Benzydamine HCl Lozenges benzydamine HCl - Healthy Volunteers, Palatability | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 120 | 2025-04-13 | 2025-09-30 |
| Real-world Clinical Response to Cenobamate Early add-on in France, Germany and Spain Cenobamate - Focal Epilepsy With and Without Secondary Generalization | Recruiting | Aziende Chimiche Riunite Angelini Francesco S.p.A | 300 | 2024-12-19 | 2025-09-19 | |
| REACH: RWE Retrospective Study to Evaluate Cenobamate Impact on Health Care Resource Utilization Epilepsy With Uncontrolled Focal-onset Seizures | Recruiting | Aziende Chimiche Riunite Angelini Francesco S.p.A | 200 | 2024-12-19 | 2025-10-02 | |
| The Effectiveness of Heat Treatment on Knee Pain in Patients With Osteoarthritis - an International, Multicenter Clinical Investigation Knee Heatwraps - Pain Management, Osteoarthritis | Not applicable | Recruiting | Aziende Chimiche Riunite Angelini Francesco S.p.A | 80 | 2024-10-21 | 2025-09-08 |
| Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state. 150 mg trazodone hydrochloride, 300 mg trazodone hydrochloride - Bioavailability Heathy Volunteers, Bioavailability Study | Phase 1 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 64 | 2024-05-22 | 2025-09-03 |
| Adjunctive Anti-seizure Medication (ASM) Real World Evidence (RWE) Study ASM as adjunctive therapy - Epilepsy | Active not recruiting | Aziende Chimiche Riunite Angelini Francesco S.p.A | 300 | 2023-05-02 | 2025-09-10 | |
| The Effectiveness of Sustained Heat Treatment on Delayed-Onset Muscle Soreness (DOMS) ThermaCare HeatWraps - Delayed-Onset Muscle Soreness (DOMS) | Not applicable | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 102 | 2023-01-30 | 2024-04-04 |
| This is a Retrospective Study on the Use of CENOBAMATE as Adjunctive Treatment in Patients Suffering From Epilepsy in Early Access Program in Germany, France and UK Focal Onset Seizure, Epilepsy | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 319 | 2023-01-27 | 2024-02-09 | |
| Cenobamate in Adults With Focal-Onset Seizures Epilepsy, Focal-Onset Seizure | Active not recruiting | Aziende Chimiche Riunite Angelini Francesco S.p.A | 936 | 2023-01-24 | 2025-09-08 | |
| Lurasidone Non-Interventional Study in Schizophrenia Patients Lurasidone - Schizophrenia | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 61 | 2022-10-21 | 2024-08-01 | |
| New Paediatric Formulation of Tachipirina® Tachipirina® 120 mg/5 mL oral suspension, new flavour - Healthy | Not applicable | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 20 | 2022-04-09 | 2024-04-10 |
| Dalbavancin Real-life Utilization in Diabetic Patients Suffering From Infections (DALBADIA) Dalbavancin - Diabetes, Infection | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 98 | 2022-01-02 | 2022-09-21 | |
| Benzydamine Oromucosal Solution in Oral Mucositis (BOOM) Benzydamine Hydrochloride 0.15% w/v oromucosal solution - Radiation-Induced Mucositis, Head and Neck Cancer | Phase 4 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 100 | 2021-12-06 | 2022-11-16 |
| Efficacy of the Combination of Ibuprofen and Paracetamol in Acute Non-specific Low Back Pain Tachifene, Brufen - Low Back Pain | Phase 4 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 176 | 2021-12-01 | 2023-01-31 |
| Different Dosage Regimens of Methocarbamol/Paracetamol in Acute Non-specific Low Back Pain. MioPain Study 380 mg/300 mg comprimidos metocarbamol/paracetamol - 4 times daily, 380 mg/300 mg comprimidos metocarbamol/paracetamol - 6 times daily - Low Back Pain | Phase 4 | Terminated | Aziende Chimiche Riunite Angelini Francesco S.p.A | 172 | 2021-10-07 | 2025-01-31 |
| Benzydamine in Sore Throat Pain Relief (BePaiR Study) 0.3% benzydamine hydrochloride spray oromucosal solution, Single 3 mg lozenge of benzydamine hydrochloride (mint flavour) - Acute Sore Throat | Phase 4 | Completed | Aziende Chimiche Riunite Angelini Francesco S.p.A | 356 | 2020-08-13 | 2021-07-22 |
| Treatment of Breakthrough Cancer Pain According to European Guidelines Breakthrough Cancer Pain | Terminated | Aziende Chimiche Riunite Angelini Francesco S.p.A | 131 | 2020-08-11 | 2021-10-27 |
Showing 20 of 42. Sign in to see all of them.
Epilepsy (6) · Seizures (4) · Depressive Disorder, Major (3) · Diabetic Neuropathies (2) · Low Back Pain (2) · Neuralgia (2) · Schizophrenia (2) · Agnosia (1) · Albuminuria (1) · Bipolar Disorder (1) · Cellulitis (1) · Coronary Restenosis (1) · Depression (1) · Diabetes Mellitus (1) · Diabetic Nephropathies (1)
Trazodone (7) · Benzydamine (5) · Ibuprofen (5) · Acetaminophen (3) · Suspensions (3) · Econazole (2) · Lurasidone Hydrochloride (2) · bindarit (2) · dalbavancin (2) · Aripiprazole (1) · Cenobamate (1) · Cetylpyridinium (1) · Daptomycin (1) · Gabapentin (1) · Levofloxacin (1)
Italy (16) · Switzerland (14) · Poland (8) · Spain (5) · France (4) · Germany (4) · United Kingdom (4) · Czechia (3) · Hungary (3) · Greece (2) · Netherlands (2) · Slovenia (2) · Austria (1) · Belgium (1) · Bulgaria (1)
Milko Radicioni, MD (8) · Milko Radicioni (2) · Antonio Colombo, MD (1) · Felix Rosenow (1) · Filippo Bogetto, MD (1) · Giuseppe Remuzzi, PhD (1) · Paolo Calabresi (1) · Raffaele Antonelli Incalzi (1) · Rhys Thoma (1) · Russell Chin (1) · Solomon Tesfaye, MD (1) · Stephen Tisi (1) · Sylvain Rheims (1)
PMID 27038924, PMID 31240596, PMID 31852003, PMID 32410819, PMID 32488885, PMID 32888085, PMID 32936427, PMID 36519620, PMID 38211660, PMID 38850402, PMID 38914876, PMID 39501351
2016 (2), 2008 (1), 2014 (1), 2018 (1), 2019 (1)