Tranylcypromine: Clinical Trials

29 trials of Tranylcypromine, newest first

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17 completed, 8 unknown, 3 terminated, 1 not yet recruiting. 14 Phase 4, 7 Phase 1, 5 Not applicable, 3 Phase 2, 2 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 414Completed 8, Unknown 3, Terminated 2, Not yet recruiting 1
Phase 17Completed 5, Unknown 2
Not applicable5Completed 4, Unknown 1
Phase 23Unknown 2, Completed 1
Phase 32Terminated 1, Unknown 1

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction
Transamine 10% IV/IM Solution for Injection, %0.9 Saline - Middle Ear Disease
Not applicableCompletedTC Erciyes University1002024-12-012025-09-08
Efficacy of Hydroxyzine for Patients With Panic Disorder
Hydroxyzine, Escitalopram Oxalate - Panic Disorder
Phase 4Not yet recruitingSultan Qaboos University802023-12-302023-02-21
Comparison of the Efficacy of Misoprostol and Tranexamic Acid for Postpartum Hemorrhage Prophylaxis in Cesarean Delivery
Tranexamic acid, Misoprostol 200mcg Tab - Postpartum Hemorrhage, Cesarean Section Complications
Phase 4CompletedAnkara Etlik City Hospital1922023-12-012026-08-06
Comparison Effectiveness of Rectal Misoprostol & Intravenous Tranexamic Acid Reducing Hemorrhage in Myomectomy
Cytotec 200Mcg Tablet, Transamine - Hemorrhage, Surgical, Myoma;Uterus
UnknownAnkara Etlik City Hospital752023-09-012023-11-02
Kaolin-based Hemostatic Gauze in Total Knee Arthroplasty
Tranexamic acid injection, apply the QCG, apply surgical gauze - Total Blood Loss, Arthropathy of Knee Joint
Phase 4CompletedChang Gung Memorial Hospital1402022-03-162026-07-22
Tranexamic Acid in Sleeve Gastrectomy
Transamine 200mg iv - Tranexamic Acid Adverse Reaction
Not applicableCompletedGoztepe Prof Dr Suleyman Yalcın City Hospital2002022-01-012023-01-25
Comparison of Chemical Peeling Agent With Transamine for Treatment of Melasma
Glycolic Acid 70%, Tranexamic acid injection - Melasma
Phase 1CompletedCombined Military Hospital Abbottabad542021-06-012022-05-05
Blood-saving Effect of Combined Intravenous Tranexamic Acid With Topical Floseal® Application Total Hip Arthroplasty
intravenous application of tranexamic acid, Floseal hemostatic matrix, Normal saline - Hip Replacement, Total
Phase 4UnknownChang Gung Memorial Hospital902018-08-152020-01-18
Combined Topical Tranexamic Acid With Floseal® in Total Knee Arthroplasty
Topical tranexamic acid, Floseal®, rivaroxaban (10mg) - Osteoarthritis, Knee
Phase 4CompletedChang Gung Memorial Hospital702017-09-122021-08-10
Tranexamic Acid for Spontaneous Acute Cerebral Hemorrhage Trial
Tranexamic Acid - Stroke Hemorrhagic, Intracerebral Haemorrhage
Phase 3UnknownKwong Wah Hospital2202017-04-012019-10-17
Topical Tranexamic Acid and Floseal® in Total Knee Arthroplasty
Topical tranexamic acid, Floseal®, Enoxaparin - Osteoarthritis, Knee
Phase 4UnknownChang Gung Memorial Hospital902016-09-012016-08-12
Comparison of Topical and Infusion Tranexamic Acid After Total Knee Arthroplasty
Tranexamic Acid 5%,5ml/amp, rivaroxaban (10mg), 0.9% Normal Saline - Osteoarthritis, Knee
Phase 4UnknownChang Gung Memorial Hospital902015-06-012015-05-27
Study of Sensitization of Non-M3 AML Blasts to ATRA by Epigenetic Treatment With Tranylcypromine (TCP)
tranylcypromine, all-trans retinoic acid, cytarabine - Acute Myeloid Leukemia, Myelodysplastic Syndrome
Phase 1 / Phase 2UnknownMichael Luebbert602015-05-012018-10-18
Study of TCP-ATRA for Adult Patients With AML and MDS
Tranylcypromine, Tretinoin - Acute Myelogenous Leukemia, Myelodysplastic Syndromes
Phase 1CompletedUniversity of Miami172015-03-022020-07-21
Pharmacovigilance in Gerontopsychiatric Patients
Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression
Phase 3TerminatedHannover Medical School4072015-01-012018-02-28
Phase I/II Trial of ATRA and TCP in Patients With Relapsed or Refractory AML and no Intensive Treatment is Possible
Tranylcypromine, Tretinoin - AML
Phase 1 / Phase 2UnknownMartin-Luther-Universität Halle-Wittenberg162014-09-012015-07-07
Interpersonal Psychotherapy for Treatment Resistant Depression
IPT+ antidepressant drugs, fluoxetine, sertraline - Treatment Resistant Depression
Not applicableUnknownHospital de Clinicas de Porto Alegre742013-04-012013-07-11
The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis
Tranexamic Acid 5%,5ml/amp (intraoperative), Tranexamic Acid 5%,5ml/amp (3 hours after operation), 0.9% Normal Saline (intraoperative) - Osteoarthritis, Knee
Phase 4CompletedChang Gung Memorial Hospital2942012-08-012015-06-01
Reduction Bleeding in Laminectomy With Double Doses of Tranexamic Acid
tranexamic acid, 0.9% NaCl - Bleeding
Phase 4CompletedMahidol University782012-06-012013-12-18
Tranylcypromine Treatment of Bipolar Depression
Tranylcypromine - Bipolar Disorder I or II
Phase 4CompletedNew York State Psychiatric Institute72011-11-012018-03-15

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Conditions studied

Depression (5)  ·  Depressive Disorder, Major (5)  ·  Depressive Disorder, Treatment-Resistant (4)  ·  Osteoarthritis, Knee (4)  ·  Postoperative Hemorrhage (4)  ·  Bipolar Disorder (3)  ·  Hemorrhage (2)  ·  Leukemia, Myeloid, Acute (2)  ·  Myelodysplastic Syndromes (2)  ·  Anxiety Disorders (1)  ·  Blood Loss, Surgical (1)  ·  Cerebral Hemorrhage (1)  ·  Dementia (1)  ·  Exsanguination (1)  ·  Fasting (1)

Sponsors

Chang Gung Memorial Hospital (6)  ·  New York State Psychiatric Institute (3)  ·  Ankara Etlik City Hospital (2)  ·  National Institute of Mental Health (NIMH) (2)  ·  Combined Military Hospital Abbottabad (1)  ·  Duke University (1)  ·  Goztepe Prof Dr Suleyman Yalcın City Hospital (1)  ·  Hannover Medical School (1)  ·  Hospital de Clinicas de Porto Alegre (1)  ·  Kwong Wah Hospital (1)  ·  Mahidol University (1)  ·  Martin-Luther-Universität Halle-Wittenberg (1)  ·  Michael Luebbert (1)  ·  Okayama University (1)  ·  Par Pharmaceutical, Inc. (1)

Countries

United States (10)  ·  Taiwan (6)  ·  Turkey (Türkiye) (4)  ·  Germany (3)  ·  Brazil (1)  ·  Hong Kong (1)  ·  Pakistan (1)  ·  Thailand (1)

Top investigators

Jun-Wen Wang, MD (5)  ·  A. John Rush, MD (1)  ·  Antonio Pizzaro (1)  ·  Carsten Mueller-Tidow, Prof. (1)  ·  Gary Sachs, M.D. (1)  ·  Helge Frieling, Prof., MD (1)  ·  Italo Biaggioni, MD (1)  ·  Jill S. Compton, PhD (1)  ·  Jonathan W. Stewart, MD (1)  ·  Jun-Wen Wang (1)  ·  Justin Watts, MD (1)  ·  Manee Raksakietisak, MD (1)  ·  Marcelo PA Fleck, MD,PhD (1)

Results publications

PMID 10662747, PMID 11765093, PMID 11904109, PMID 11927799, PMID 12119802, PMID 12832331, PMID 15005752, PMID 15066944, PMID 15110730, PMID 15330403, PMID 15349007, PMID 15465989, PMID 15541061, PMID 15569893, PMID 15677618, PMID 15710782, PMID 15723025, PMID 15738343, PMID 15898966, PMID 15950022, PMID 15960566, PMID 16023735, PMID 16168792, PMID 16176440, PMID 16197928, PMID 16338761, PMID 16339615, PMID 16339616, PMID 16390886, PMID 16426088, PMID 16426099, PMID 16448626, PMID 16449473, PMID 16449474, PMID 16457894, PMID 16551710, PMID 16552982, PMID 16554525, PMID 16554526, PMID 16566612, PMID 16566627, PMID 16566901, PMID 16595351, PMID 16635643, PMID 16636629, PMID 16642436, PMID 16675760, PMID 16677228, PMID 16690084, PMID 16754414

NIH funding

R34MH073677 (1), RC1MH088405-01 (1)