9 completed, 8 unknown, 7 recruiting, 3 active not recruiting. 12 Not applicable, 4 Phase 3, 3 Phase 4, 1 Phase 1, 1 Phase 2.
Follow Mitral Stenosis: new trials by email Literature Review of Mitral Stenosis trials Research Report on Mitral Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral SAPIEN X4 THV - Mitral Regurgitation, Mitral Valve Disease | Not applicable | Not yet recruiting | Edwards Lifesciences | 125 | 2027-01-01 | 2025-12-22 |
| TransCatheter Replacement Of the Mitral Valve With the Novel Cephea Mitral Valve System Cephea Mitral Valve System - Mitral Valve Disease, Mitral Annulus Calcification | Not applicable | Recruiting | Abbott Medical Devices | 565 | 2026-10-21 | 2026-11-13 |
| Abbott Cephea Mitral Valve Disease Registry Mitral Regurgitation, Mitral Stenosis | Recruiting | Abbott Medical Devices | 1000 | 2025-08-13 | 2026-09-10 | |
| Early Feasibility Study of Surgical Implantation of a Polymer Prosthetic Mitral and Aortic Valve Polymer Prosthetic Heart Valve - AORTIC VALVE DISEASES, Mitral Valve Disease | Not applicable | Recruiting | Mitrassist Lifesciences Limited Co., Ltd. | 10 | 2025-06-27 | 2025-07-31 |
| Cephea South America Feasibility Study Cephea Mitral Valve System - Mitral Regurgitation, Mitral Stenosis | Not applicable | Active not recruiting | Abbott Medical Devices | 20 | 2025-06-17 | 2026-09-11 |
| Prospective Multicenter Registry of Patients With Mitral Stenosis Undergoing Percutaneous Mitral Balloon Commissurotomy Mitral Stenosis | Recruiting | Asan Medical Center | 400 | 2025-05-01 | 2025-09-16 | |
| Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis Mitral Stenosis | Recruiting | Gazi University | 40 | 2025-01-13 | 2026-08-04 | |
| Mild ANH on Pre-bypass Coagulation Function During Cardiac Surgery Acute normovolemic hemodilution (ANH), hydroxyethyl starch (HES 130/0.6) - Mitral Regurgitation, Mitral Stenosis | Not applicable | Not yet recruiting | Konkuk University Medical Center | 70 | 2024-10-28 | 2024-10-31 |
| Prevalence, Risk Factors, and Clinical Outcomes of Valvular Heart Disease Transthoracic echocardiography, wearable synchronous electrocardiogram-phonocardiogram - Aortic Stenosis, Aortic Regurgitation | Enrolling by invitation | Beijing Anzhen Hospital | 12000 | 2024-07-18 | 2026-11-13 | |
| Impact of Percutaneous Transvenous Mitral Commissurotomy on The Left Atrial Appendage Function in Patients With Mitral Stenosis. Transesophageal echocardiography - Mitral Stenosis | Not applicable | Not yet recruiting | Assiut University | 25 | 2024-07-01 | 2024-04-02 |
| Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients Ultrasound examination of the lungs - Ischemic Heart Disease, Aortic Stenosis, Severe | Not applicable | Recruiting | Saint Petersburg State University, Russia | 186 | 2024-05-15 | 2024-12-09 |
| Assessment of Right Ventricular Function in Patients With Severe Mitral Stenosis Before and After Balloon Mitral Valvuloplasty Mitral Stenosis | Unknown | Assiut University | 30 | 2023-10-01 | 2023-10-05 | |
| The China Mviv Registry Transseptal Transcatheter Mitral valve-in-valve Replacement - Bioprosthesis Failure, Mitral Stenosis With Insufficiency | Not applicable | Unknown | Xiamen Cardiovascular Hospital, Xiamen University | 50 | 2023-07-11 | 2023-06-29 |
| Clinical Investigation for the Foldax Tria Mitral Valve- India Mitral Valve Replacement - Mitral Valve Disease, Mitral Regurgitation | Not applicable | Unknown | Foldax, Inc | 70 | 2023-03-01 | 2024-01-05 |
| Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm Ivabradine, Beta blocker - Mitral Stenosis | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 42 | 2023-02-01 | 2024-04-17 |
| Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve MITRIS RESILIA Mitral Valve, Model 11400M - Mitral Stenosis, Mitral Valve Insufficiency | Active not recruiting | Edwards Lifesciences | 504 | 2023-01-11 | 2026-05-22 | |
| Dapagliflozin Effect on Rheumatic Mitral Stenosis Dapagliflozin - Rheumatic Heart Disease, Heart Failure | Phase 3 | Unknown | Universitas Sebelas Maret | 36 | 2022-12-01 | 2022-11-21 |
| Polish Transcatheter Transfemoral Mitral Valve-in-Valve Implantation (Mitral ViV) Registry Transcatheter mitral valve-in-valve implantation - Mitral Insufficiency, Mitral Stenosis | Unknown | Medical University of Warsaw | 100 | 2022-10-17 | 2022-11-23 | |
| Left Atrial Appendage (LAA) Clot With Severe Mitral Stenosis WARFARIN - Left Atrial Appendage Aneurysm, Mitral Stenosis | Unknown | University of Karachi | 52 | 2021-12-01 | 2022-01-11 | |
| The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves). Transseptal ViMAC - Mitral Annular Calcification, Mitral Stenosis | Not applicable | Recruiting | Mayra Guerrero | 210 | 2021-03-08 | 2026-01-13 |
Showing 20 of 32. Sign in to see all of them.
Mitral Valve Stenosis (32) · Mitral Valve Insufficiency (18) · Aortic Valve Stenosis (5) · Heart Failure (5) · Tricuspid Valve Insufficiency (5) · Aortic Valve Insufficiency (4) · Rheumatic Heart Disease (4) · Heart Valve Diseases (3) · Atrial Fibrillation (2) · Gastroesophageal Reflux (2) · Aneurysm, Ascending Aorta (1) · Aortic Valve Disease (1) · Coronary Artery Disease (1) · Fibrosis (1) · Motor Activity (1)
Cardiovascular Diseases (32) · Heart Diseases (32) · Heart Valve Diseases (29) · Ventricular Outflow Obstruction (5) · Aortic Valve Disease (4) · Bacterial Infections (4) · Bacterial Infections and Mycoses (4) · Gram-Positive Bacterial Infections (4) · Infections (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Rheumatic Fever (3) · Streptococcal Infections (3) · Vascular Diseases (3) · Arrhythmias, Cardiac (2)
Hydroxyethyl Starch Derivatives (3) · Warfarin (3) · Ivabradine (2) · Adrenergic beta-Antagonists (1) · Atenolol (1) · Bosentan (1) · Cardiac Surgical Procedures (1) · Control Groups (1) · Dabigatran (1) · Echocardiography (1) · Echocardiography, Transesophageal (1) · Metoprolol (1) · Models, Biological (1) · Percutaneous Coronary Intervention (1) · Ramipril (1)
Abbott Medical Devices (3) · Edwards Lifesciences (3) · Konkuk University Medical Center (3) · Assiut University (2) · Asan Medical Center (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Beijing Anzhen Hospital (1) · Federal University of Bahia (1) · Foldax, Inc (1) · French Cardiology Society (1) · Gazi University (1) · General Hospital of Chalkida (1) · Govind Ballabh Pant Hospital (1) · Mayra Guerrero (1) · Medical University of Bialystok (1)
United States (5) · South Korea (4) · China (3) · Poland (3) · Brazil (2) · Canada (2) · India (2) · Indonesia (2) · United Kingdom (2) · Bangladesh (1) · Chile (1) · Fiji (1) · France (1) · Germany (1) · Greece (1)
Ade Meidian Ambari, MD,FIHA (1) · Adrian VS Hill, DPhil DM (1) · Amar Krishnaswamy, MD (1) · An Aldia Asrial, MD (1) · Andrew C Steer, FRACP PhD (1) · Barathi Sethuraman (1) · Dr Neeraj Parakh, MD, DM (1) · Gorav Ailawadi, MD (1) · James McCabe, MD (1) · John Puskas, MD (1) · Majid Maleki, M.D. (1) · Mariana Mirabel, MD (1) · Mayra Guerrero, MD (1)
PMID 28605428, PMID 29699609, PMID 31933658, PMID 32340804, PMID 32661631, PMID 32978200, PMID 34191132, PMID 34518254, PMID 35065065, PMID 35306032, PMID 37778503, PMID 37808026, PMID 38135262, PMID 39780838, PMID 40589299, PMID 40748697, PMID 41960126