298 completed, 65 unknown, 29 terminated, 24 recruiting. 117 Phase 1, 83 Phase 3, 81 Phase 4, 55 Not applicable, 51 Phase 2.
Follow Warfarin: new trials by email Literature Review of Warfarin trials Research Report on Warfarin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LVT DURATION: Pilot Study of Anticoagulation Duration for Left Ventricular Thrombus Continue rivaroxaban or apixaban or warfarin, Discontinue rivaroxaban or apixaban or warfarin - Left Ventricular Thrombus | Phase 2 | Not yet recruiting | Queen Mary University of London | 120 | 2026-12-01 | 2026-02-27 |
| Predicting Response and Exposure Changes in Cirrhosis for Effectiveness Five-Drug CYP Probe Cocktail - Liver Cirrhosis | Not applicable | Not yet recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 45 | 2026-11-01 | 2026-08-11 |
| SWITCH: Apixaban vs Vitamin K in HM3 Warfarin, Apixaban - LVAD (Left Ventricular Assist Device) Thrombosis, Heart Failure | Phase 3 | Not yet recruiting | Columbia University | 460 | 2026-08-01 | 2026-08-31 |
| Aspirin Monotherapy Versus Sequential Warfarin-Aspirin Therapy After TAVR in Patients With Pure Aortic Regurgitation Aspirin, Warfarin - Aortic Regurgitation Disease | Not applicable | Recruiting | Shanghai Zhongshan Hospital | 1172 | 2026-07-18 | 2026-08-10 |
| A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight UBT251, Cocktail (Warfarin/Caffeine/Midazolam) - Obesity, Overweight | Phase 1 | Recruiting | Novo Nordisk A/S | 44 | 2026-07-15 | 2026-08-18 |
| An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis Afimkibart, Caffeine, Warfarin - Active Ulcerative Colitis | Phase 1 | Recruiting | Hoffmann-La Roche | 25 | 2026-06-29 | 2026-10-16 |
| STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD Pump Warfarin (INR 2-3) with placebo, Warfarin (INR 2-3) with aspirin - LVAD (Left Ventricular Assist Device) Thrombosis, LVAD | Phase 4 | Not yet recruiting | China National Center for Cardiovascular Diseases | 370 | 2026-06-25 | 2026-06-12 |
| Apixaban Versus Warfarin for Left Ventricular Thrombus Apixaban, Warfarin - Left Ventricular Thrombus | Phase 3 | Recruiting | University of Arizona | 218 | 2026-06-22 | 2026-07-17 |
| STRATEGY-PE: Real-World Treatment Strategies for Intermediate-High Risk Pulmonary Embolism Anticoagulants, Thrombolytic Agents, Mechanical Thrombectomy Devices - Pulmonary Embolism, Venous Thromboembolism | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 1300 | 2026-06-01 | 2026-05-22 | |
| Phase I Drug-Drug Interaction Study of UBT251 Injection in Participants With Overweight or Obesity UBT251, Metformin hydrochloride, Warfarin Sodium - Drug Drug Interaction (DDI), Pharmacokinetics and Pharmacodynamics | Phase 1 | Recruiting | The United Bio-Technology (Hengqin) Co., Ltd. | 48 | 2026-05-27 | 2026-08-25 |
| Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants ZT002 injection, metformin, warfarin, ZT002 injection, rosuvastatin, digoxin - Overweight,Obesity | Phase 1 | Active not recruiting | Beijing QL Biopharmaceutical Co.,Ltd | 60 | 2026-05-27 | 2026-10-21 |
| Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves LMWH and LDA, Vitamin K antagonists (e.g warfarin)+/- LDA, Sequential therapy +/- LDA - Pregnancy, Prosthetic Heart Valve | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 100 | 2026-05-26 | 2026-06-22 |
| Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin Acetaminophen, Metformin, Warfarin - Overweight, Obesity | Phase 1 | Not yet recruiting | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 42 | 2026-04-08 | 2026-03-30 |
| Apixaban VS Warfarin in AF Pts First Three Months After Repair or BIO AVR MVR Apixaban, Warfarin - Valve Disease, Heart, Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Meshalkin Research Institute of Pathology of Circulation | 120 | 2026-02-01 | 2026-02-25 |
| Study on Gastric Emptying Effect and Drug-Drug Interactions of GZR18 Injection GZR18 injection,digoxin tablets, rosuvastatin calcium tablets and warfarin sodium tablets - Obesity or Overweight | Phase 1 | Recruiting | Gan & Lee Pharmaceuticals. | 60 | 2025-11-17 | 2025-12-12 |
| Rivaroxaban vs Warfarin in Patients With Mechanical Heart Valves Rivoroxaban, Warfarin - Valvular Heart Disease Patients | Phase 3 | Enrolling by invitation | Rawalpindi Institute of Cardiology | 60 | 2025-11-13 | 2026-03-16 |
| Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD Patients Warfarin (low-intensity anticoagulation), Warfarin (standard anticoagulation) - Advanced Heart Failure, Left Ventricular Assist Devices | Phase 4 | Not yet recruiting | Asan Medical Center | 94 | 2025-10-01 | 2025-07-23 |
| A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and Warfarin Metformin, Empagliflozin, Midazolam - Overweight Subject, Healthy Subjects | Phase 1 | Recruiting | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 111 | 2025-09-24 | 2026-01-09 |
| Vitamin K for Perioperative Warfarin Management Vitamin K, Warfarin (standard without loading), Warfarin (standard with loading) - Anticoagulant Therapy | Phase 4 | Recruiting | University of Michigan | 20 | 2025-07-03 | 2026-04-13 |
| Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki Disease Rivaroxaban Oral Tablet [Xarelto], Aspirin or Clopidogrel, Warfarin - Kawasaki Disease, Coronary Artery Aneurysm | Phase 4 | Recruiting | Children's Hospital of Fudan University | 100 | 2025-06-01 | 2026-07-06 |
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Atrial Fibrillation (109) · Stroke (43) · Venous Thrombosis (38) · Thrombosis (34) · Venous Thromboembolism (30) · Thromboembolism (25) · Pulmonary Embolism (24) · Hemorrhage (19) · Cardiovascular Diseases (12) · Embolism (12) · Ischemic Stroke (11) · Heart Valve Diseases (10) · Liver Cirrhosis (10) · Diabetes Mellitus, Type 2 (9) · Obesity (9)
Boehringer Ingelheim (25) · Bayer (17) · AstraZeneca (11) · Eli Lilly and Company (11) · Pfizer (10) · Brigham and Women's Hospital (9) · Bristol-Myers Squibb (9) · Daiichi Sankyo (8) · Janssen Research & Development, LLC (7) · Jiangsu HengRui Medicine Co., Ltd. (6) · Bial - Portela C S.A. (5) · Meshalkin Research Institute of Pathology of Circulation (5) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Novo Nordisk A/S (5) · Astellas Pharma Inc (4)
United States (163) · China (64) · Canada (57) · Germany (45) · United Kingdom (41) · South Korea (33) · France (32) · Brazil (29) · Russia (28) · Italy (27) · Netherlands (26) · Spain (26) · Denmark (25) · Japan (25) · Israel (24)
Shirley Wang, PhD, ScM (5) · Dou-Sheng Bai, MD (2)
PMID 24081972, PMID 27807306, PMID 23659733, PMID 23991661, PMID 24344086, PMID 25717286, PMID 25851062, PMID 26627989, PMID 27056738, PMID 27569438, PMID 29069359, PMID 29655662, PMID 31752643, PMID 32984892, PMID 33292046, PMID 33741689, PMID 33766266, PMID 34358298, PMID 35570249, PMID 35902169, PMID 36990261, PMID 40925065, PMID 10591382, PMID 11546885, PMID 12045168, PMID 12917889, PMID 12968085, PMID 13678932, PMID 15232117, PMID 15546539, PMID 16494639, PMID 17221328, PMID 17634457, PMID 17851566, PMID 18294998, PMID 18497320, PMID 18705914, PMID 18815396, PMID 18990504, PMID 19062079, PMID 19114462, PMID 19229428, PMID 19250106, PMID 19348685, PMID 19376304, PMID 19380621, PMID 19640572, PMID 19683639, PMID 19690349, PMID 19717844
2016 (6), 2014 (4), 2015 (4), 2005 (3), 2009 (2), 2017 (2), 2018 (2), 2008 (1), 2019 (1), 2025 (1), K24HL179410 (1), P01GM032165 (1), P50HL054502 (1), R01GM089994 (1), R01HL033233 (1)