4820 completed, 980 unknown, 642 recruiting, 387 terminated. 1436 Not applicable, 1346 Phase 2, 1289 Phase 3, 918 Phase 1, 751 Phase 4.
Follow Bacterial Infections and Mycoses: new trials by email Literature Review of Bacterial Infections and Mycoses trials Research Report on Bacterial Infections and Mycoses
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of Clinical Benefit and Safety Following CYFENDUS Administration for Post-Exposure Prophylaxis of Anthrax Disease. CYFENDUS - Anthrax | Not yet recruiting | Emergent BioSolutions | 250 | 2035-11-01 | 2025-12-08 | |
| Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans Integrated care - Opioid Use Disorder, HIV | Not applicable | Not yet recruiting | VA Office of Research and Development | 60 | 2028-04-03 | 2026-04-24 |
| Improving Clinic Delivery of HIV-related Anal Health Services PEACHES 2.0 Implementation Strategies - HIV, Gonorrhea | Not applicable | Not yet recruiting | Albert Einstein College of Medicine | 8 | 2028-02-01 | 2026-10-13 |
| A Field Study Evaluating Clinical Benefit and Safety of AIGIV (ANTHRASIL®) in Inhalational Anthrax Patients AIGIV - Inhalational Anthrax | Not yet recruiting | Emergent BioSolutions | 100 | 2027-05-30 | 2026-02-06 | |
| Observational Study of Raxibacumab in Sporadic Cases of Systemic Anthrax Collection of samples - Infections, Bacterial | Not yet recruiting | Emergent BioSolutions | 10 | 2027-05-01 | 2026-03-17 | |
| Advanced HIV Re-engagement in Care ARC - Advanced HIV Disease | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 724 | 2027-05-01 | 2026-07-23 |
| Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial Sulbactam 25mg/kg -Durlobactam 25mg/kg (Every 6 hours), Ceftriaxone for Injection, Amoxicillin - Mycobacterium Abscessus Pulmonary Disease, Mycobacterium Abscessus Infection | Phase 2 | Not yet recruiting | The University of Queensland | 300 | 2027-04-01 | 2026-03-20 |
| Doxycycline Boosted Therapy in Lyme Borreliosis: DoBo Study. Hydroxychloroquin, Placebo, Doxycycline - Lyme Borreliosis, Nervous System | Phase 4 | Not yet recruiting | Radboud University Medical Center | 50 | 2027-03-01 | 2026-08-27 |
| A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV) Treatment metronidazole (MTZ)+ LCFA-01 placebo + LC103 placebo, metronidazole (MTZ)+ LCFA-01 + LC103 placebo, metronidazole (MTZ)+ LC103 + LCFA-01 placebo - Bacterial Vaginosis | Phase 1 | Not yet recruiting | Massachusetts General Hospital | 280 | 2027-02-03 | 2026-10-15 |
| Multi-country Evaluation of Early RHD in Children Across Africa for Vaccine Trial Readiness Rheumatic Heart Disease in Children | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 7500 | 2027-02-01 | 2026-08-27 | |
| Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children Oral Penicillin V - Rheumatic Heart Disease in Children | Phase 3 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 9622 | 2027-02-01 | 2026-09-03 |
| Therapeutic ID93 + GLA-SE Vaccination in Participants With Rifampicin-Susceptible Pulmonary TB ID93 + GLA-SE vaccine, Placebo vaccine - Tuberculosis, Pulmonary | Phase 2 | Not yet recruiting | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 1500 | 2027-01-31 | 2026-08-24 |
| A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose Primary Dosing Series Followed by a Booster Dose at 12 to 15 Months of Age Pn-MAPS30plus, PCV20 - Pneumonia, Bacterial | Phase 1 | Not yet recruiting | GlaxoSmithKline | 60 | 2027-01-25 | 2026-07-16 |
| Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole - Cryptococcal Antigenemia, HIV-1-infection | Phase 3 | Not yet recruiting | University of Minnesota | 505 | 2027-01-05 | 2026-09-03 |
| Improving Management and Secondary Prevention Through Azithromycin Comparative Trial in Rheumatic Heart Disease in Nigeria)- IMPACT-RHD Nigeria Benzathine Penicillin, Azithromycin (Azithro) - Rheumatic Fever, Valvular Heart Diseases | Not applicable | Not yet recruiting | Ladoke Akintola University of Technology, Ogbomoso, Nigeria | 474 | 2027-01-05 | 2026-06-04 |
| A Clinical Trial of Resistant Potato Starch for Gut MDRO Decolonization Resistant Potato Starch, Maltodextrin - Clostridium Infections, Methicillin-resistant Staphylococcus Aureus (MRSA) | Phase 2 | Not yet recruiting | VA Office of Research and Development | 120 | 2027-01-01 | 2026-08-28 |
| Clinical Benefit and Safety of Raxibacumab in Patients With Symptomatic Inhalational Anthrax in a Mass Exposure Scenario Sample Collection - Infections, Bacterial | Phase 4 | Not yet recruiting | Emergent BioSolutions | 100 | 2027-01-01 | 2026-02-06 |
| Primary Prophylaxis of Clostridioides Difficile Infection With Oral Vancomycin Vancomycin (POC) - Clostridioides Difficile, Vancomycin Resistance Enterococcus Faecium | Phase 2 / Phase 3 | Withdrawn | University of Maryland, Baltimore | 2027-01-01 | 2026-07-29 | |
| Bacterial Decolonization to Prevent Severe Radiation Dermatitis in Head and Neck Squamous Cell Carcinoma Bacterial decolonization, Standard Hygiene Measures - HNSCC | Not applicable | Not yet recruiting | Institut Cancerologie de l'Ouest | 144 | 2027-01-01 | 2026-10-22 |
| Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa VPM1002 Vaccine, BCG Vaccine, Placebo - Tuberculosis, HIV Infections | Phase 1 / Phase 2 | Withdrawn | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | 2026-12-31 | 2026-08-17 |
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Tuberculosis (1142) · Bacterial Infections (583) · HIV Infections (340) · Tuberculosis, Pulmonary (309) · Tetanus (302) · Pneumococcal Infections (298) · Staphylococcal Infections (293) · Hidradenitis Suppurativa (280) · Acquired Immunodeficiency Syndrome (272) · Whooping Cough (269) · Mycoses (260) · Bacteremia (259) · Diphtheria (254) · Clostridium Infections (244) · Vaginosis, Bacterial (234)
Infections (7353) · Bacterial Infections (5755) · Gram-Positive Bacterial Infections (3292) · Actinomycetales Infections (1975) · Gram-Negative Bacterial Infections (1802) · Mycobacterium Infections (1655) · Pathological Conditions, Signs and Symptoms (1443) · Respiratory Tract Diseases (1393) · Urogenital Diseases (1194) · Pathologic Processes (1182) · Respiratory Tract Infections (1142) · Genital Diseases (1048) · Mycoses (1046) · Lung Diseases (1007)
Isoniazid (166) · Rifampin (158) · Azithromycin (119) · Vancomycin (111) · Fluconazole (110) · Pyrazinamide (92) · 13-valent pneumococcal vaccine (90) · Blood Specimen Collection (88) · Ethambutol (87) · Linezolid (87) · Moxifloxacin (84) · Tetanus Toxoid (83) · Meningococcal Vaccines (81) · Metronidazole (73) · Doxycycline (71)
GlaxoSmithKline (356) · National Institute of Allergy and Infectious Diseases (NIAID) (306) · Pfizer (205) · Sanofi Pasteur, a Sanofi Company (127) · Merck Sharp & Dohme LLC (122) · Assistance Publique - Hôpitaux de Paris (89) · University of Oxford (71) · Novartis Vaccines (63) · Johns Hopkins University (60) · University of California, San Francisco (51) · University of Pittsburgh (48) · Centers for Disease Control and Prevention (47) · National Taiwan University Hospital (44) · Assiut University (41) · London School of Hygiene and Tropical Medicine (40)
United States (2217) · France (589) · China (488) · South Africa (373) · Canada (369) · Germany (334) · United Kingdom (322) · Spain (309) · Italy (238) · South Korea (220) · Australia (210) · India (207) · Belgium (191) · Netherlands (188) · Brazil (185)
Helen McShane (20) · Nicholas Paton (10)
PMID 33616229, PMID 28459966, PMID 28597967, PMID 33891293, PMID 30597021, PMID 31280481, PMID 34922058, PMID 35164991, PMID 36396498, PMID 40122135, PMID 42286373, PMID 25466778, PMID 31110098, PMID 35257644, PMID 36808186, PMID 41245385, PMID 19819004, PMID 22461716, PMID 27518661, PMID 27568215, PMID 28043488, PMID 28063795, PMID 29380251, PMID 30075748, PMID 30716446, PMID 31411386, PMID 31589610, PMID 31604104, PMID 33020485, PMID 33326848, PMID 33542052, PMID 34741280, PMID 35776862, PMID 36746171, PMID 39230271, PMID 39972326, PMID 40277027, PMID 41248770, PMID 42525209, PMID 11115712, PMID 1347058, PMID 16531428, PMID 16640454, PMID 17287313, PMID 17301105, PMID 17716936, PMID 17957238, PMID 18444791, PMID 18444848, PMID 18508226
2019 (38), 2023 (37), 2018 (34), 2008 (25), 2017 (25), 2009 (23), 2016 (23), 2014 (22), 2015 (22), 2025 (21), 2005 (8), R01HD071779 (6), 5UL1RR024982-02 (5), U01AI068636 (4), U10CA095861 (4)