7 completed, 7 recruiting, 2 active not recruiting, 2 enrolling by invitation. 11 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 4, Recruiting 4, Enrolling by invitation 2, Not yet recruiting 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Aneurysm, Ascending Aorta: new trials by email Literature Review of Aneurysm, Ascending Aorta trials Research Report on Aneurysm, Ascending Aorta
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Lipid Metabolism and Mitochondrial Function in Myeloid Cells and Total Aortic Tissue in Patients With Ascending Thoracic Aortic Aneurysm (ATA) and Bicuspid (BA) or Tricuspid (TA) Aortic Valves. Additional blood samples, Collection of discarded ascending aortic tissue - Ascending Aortic Aneurysm | Recruiting | Centre Hospitalier Universitaire Dijon | 50 | 2026-06-28 | 2026-07-13 | |
| Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair. - Aortic Aneurysm, Aortic Aneurysm Abdominal | Not applicable | Not yet recruiting | Grena Biomed Limited | 60 | 2025-06-30 | 2025-04-09 |
| Efficacy of Self-expandable and Balloon-expandable Valves in Patients With Ascending Aortic Dilation Transcatheter aortic valve replacement - Aortic Stenosis, Ascending Aortic Dilatation | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 100 | 2024-10-15 | 2024-12-20 |
| Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients Ultrasound examination of the lungs - Ischemic Heart Disease, Aortic Stenosis, Severe | Not applicable | Recruiting | Saint Petersburg State University, Russia | 186 | 2024-05-15 | 2024-12-09 |
| Prospective Evaluation of Adventitial Histopathology in Borderline Ascending Aortic Dilatatio Ascending Aortic Aneurysm, Aortic Adventitial Pathology | Active not recruiting | Samsun University | 102 | 2023-08-01 | 2025-06-24 | |
| Aortic Stiffness in Patients With Genetic Aortopathies Pulsotonometry - Rare Diseases, Aortic Stiffness | Recruiting | IRCCS Policlinico S. Donato | 250 | 2023-02-15 | 2025-09-10 | |
| Progression of Ascending Aorta Diameters in Bicuspid Aortic Valve After Transcatheter or Surgical Replacement. Echocardiographic assessment., Computed-tomography assessment - Bicuspid Aortic Valve, Aortic Valve Stenosis | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 150 | 2023-01-20 | 2023-02-01 | |
| Full Sternotomy vs Mini-sternotomy for Ascending Aortic Pathology Full sternotomy, J-shaped mini-sternotomy - Ascending Aortic Aneurysm | Not applicable | Recruiting | Tomsk Cardiology Research Institute | 200 | 2022-07-10 | 2026-02-05 |
| Biomechanical Properties of the Human Ascending Aortic Wall in Aneurysm Surgery - Ascending Aortic Aneurysm | Not applicable | Completed | Tomsk National Research Medical Center of the Russian Academy of Sciences | 50 | 2022-03-21 | 2026-06-24 |
| Fate at Long-term of Mild to Moderate Bicuspid Aortic Valve Disease Left Untreated at the Time of Supracoronary Ascending Aorta Replacement Ascending aorta replacement - Bicuspid Aortic Valve, Ascending Aorta Aneurysm | Completed | Michele De Bonis | 75 | 2020-12-04 | 2023-05-01 | |
| Study of Treatment of Thoracic Aortic Aneurysms and Dilatation in Combination With Tricuspid and Bicuspid Aortic Valves. aortic prosthetics - Ascending Aorta Aneurysm, Dilation of the Ascending Aorta | Recruiting | Tomsk National Research Medical Center of the Russian Academy of Sciences | 80 | 2020-01-24 | 2024-11-25 | |
| Outcomes for Patients With Ascending Aortic Dilation Who Underwent TAVR Transcatheter Aortic Valve Replacement - Transcatheter Aortic Valve Replacement (TAVR), Ascending Aortic Dilation | Completed | zjq | 101 | 2019-01-01 | 2025-10-08 | |
| Strategy for Aortic Surgery Hemostasis TDM-621 - Ascending Aorta Abnormality, Ascending Aortic Dissection | Phase 2 / Phase 3 | Unknown | University of Sao Paulo General Hospital | 200 | 2018-12-04 | 2019-04-17 |
| Endovascular Treatment of Thoracic Aortic Disease Endovascular stent-graft implantation - Thoracic Aortic Aneurysms, Dissecting, Aneurysm | Not applicable | Enrolling by invitation | Matthew Eagleton | 170 | 2018-10-25 | 2026-10-22 |
| Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance Thoracic Aortic Surgery - Ascending Aortic Aneurysm Enlargement, Ascending Aorta Aneurysm | Not applicable | Recruiting | Ottawa Heart Institute Research Corporation | 610 | 2018-09-01 | 2026-09-28 |
| In Vivo Evaluation of Growth and Risk of Rupture of Dilated Ascending Aorta Using 4D Cardiac Magnetic Resonance 4D Cardiac Magnetic Resonance - Aortic Rupture | Not applicable | Completed | Centre Hospitalier Universitaire de Saint Etienne | 41 | 2017-10-11 | 2020-11-13 |
| Pathogenetic Basis of Aortopathy and Aortic Valve Disease Aortopathies, Thoracic Aortic Aneurysm | Active not recruiting | Yale University | 3000 | 2015-12-10 | 2026-02-13 | |
| Progel Vascular Sealant Progel Vascular Sealant, Gelfoam Plus - Aortic Valve Stenosis, Aneurysm of Ascending Aorta | Not applicable | Completed | C. R. Bard | 158 | 2013-11-01 | 2017-04-10 |
| Coronary Artery Bypass Grafting With Ascending Aortic Replacement ECG CT angiography, TTFM, computed tomography of the aorta and/or grafts - Coronary Artery Disease, Ascending Aortic Aneurysm | Not applicable | Completed | Tomsk Cardiology Research Institute | 70 | 2013-01-20 | 2025-07-17 |
| The Gender Specific Effect on the Results of Ascending Aortic Replacement Ascending aortic replacement - Ascending Aortic Aneurysm | Completed | Tomsk National Research Medical Center of the Russian Academy of Sciences | 200 | 2013-01-01 | 2026-06-24 |
Showing 20 of 21. Sign in to see all of them.
Aortic Valve Stenosis (5) · Bicuspid Aortic Valve Disease (3) · Aneurysm (2) · Aneurysm, Aortic Arch (2) · Aortic Aneurysm (2) · Aortic Aneurysm, Abdominal (2) · Aortic Aneurysm, Thoracic (2) · Aortic Aneurysm, Thoracoabdominal (2) · Aortic Dissection (2) · Aortic Valve Disease (2) · Aortic Valve Insufficiency (2) · Coronary Artery Disease (2) · Dissection, Ascending Aorta (2) · Heart Diseases (2)
Aortic Diseases (21) · Cardiovascular Diseases (21) · Vascular Diseases (21) · Aneurysm (19) · Aortic Aneurysm (19) · Aortic Aneurysm, Thoracic (19) · Heart Diseases (6) · Heart Valve Diseases (6) · Aortic Valve Disease (5) · Ventricular Outflow Obstruction (5) · Acute Aortic Syndrome (4) · Dissection, Blood Vessel (4) · Cardiovascular Abnormalities (3) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3)
Transcatheter Aortic Valve Replacement (2) · Gelatin Sponge, Absorbable (1) · Surgical Procedures, Operative (1) · Tomography, X-Ray Computed (1) · Transdermal Patch (1) · acetyl-(arginyl-alanyl-aspartyl-alanyl)4-amide (1)
Tomsk National Research Medical Center of the Russian Academy of Sciences (3) · Tomsk Cardiology Research Institute (2) · C. R. Bard (1) · Centre Hospitalier Universitaire Dijon (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · China National Center for Cardiovascular Diseases (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Grena Biomed Limited (1) · IRCCS Policlinico S. Donato (1) · Matthew Eagleton (1) · Michele De Bonis (1) · Ottawa Heart Institute Research Corporation (1) · Saint Petersburg State University, Russia (1) · Samsun University (1) · University of North Carolina, Chapel Hill (1)
Russia (5) · United States (5) · Italy (3) · China (2) · France (2) · Belgium (1) · Brazil (1) · Canada (1) · Poland (1) · Sweden (1) · Turkey (Türkiye) (1)
Boris N. Kozlov, MD, PhD (2) · Alessandro Pini (1) · Ali Khoynezhad, MD (1) · Benjamin Landis, MD (1) · Boris N Kozlov, Dr (1) · Dmitry S Panfilov, PhD, MD (1) · Emrah Ereren (1) · Evgeniya V Lelik, PhD (1) · Giovanni A Chiariello, MD (1) · Jehangir Appoo, MD (1) · Mark A Farber, MD (1) · Matthew J Eagleton, MD (1) · Munir Boodhwani, MD (1) · Ricardo R Dias, MD,PhD (1)
PMID 37059239, PMID 37330702, PMID 38695613, PMID 38989575, PMID 39963789, PMID 23809203, PMID 24685375, PMID 34039580, PMID 34191132, PMID 38692478