66 completed, 15 unknown, 9 terminated, 5 withdrawn. 41 Phase 4, 21 Phase 3, 14 Not applicable, 11 Phase 2, 7 Phase 1.
Follow Atenolol: new trials by email Literature Review of Atenolol trials Research Report on Atenolol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Deprescribing Beta-Blockers in Elders With Heart Failure With Preserved Ejection Fraction (DEPRESCRIBE-HFpEF) Placebo (matching), Beta-blockers - Heart Failure, HFpEF | Phase 4 | Enrolling by invitation | Weill Medical College of Cornell University | 240 | 2026-02-02 | 2026-10-16 |
| Heart Rate Control Before Cardiac Computed Tomography in Adults for the Evaluation of Coronary Artery Disease atenolol, Metoprolol tartrate, Ivabradine - Coronary Arterial Disease (CAD), Ischemic Heart Disease (IHD) | Phase 2 / Phase 3 | Enrolling by invitation | Gødstrup Hospital | 350 | 2025-12-15 | 2025-12-17 |
| Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries Atenolol Succinate Oral Tablet, Metoprolol Succinate Oral Tablet - Hypotension Drug-Induced | Phase 4 | Recruiting | Damanhour Teaching Hospital | 60 | 2025-12-01 | 2026-09-21 |
| Comparison Between Atenolol,Propnalol and Ivabradine Atenolol 50 MG, Propranolol Pill, Ivabradine - Intraoperative Bleeding | Not applicable | Completed | Menoufia University | 120 | 2023-09-01 | 2024-11-01 |
| Effect of Atenolol Versus Ivabradine on HRV in TRS Patients on Clozapine With Tachycardia: A Randomised Control Trial. Atenolol 25 mg, Ivabradine 10mg - Treatment Resistant Schizophrenia, Clozapine Adverse Reaction | Not applicable | Unknown | All India Institute of Medical Sciences, Bhubaneswar | 40 | 2023-08-01 | 2024-07-17 |
| Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol Propranolol or Carvedilol, Atenolol, Bisoprolol or Sotalol - Hypertension | Completed | Brigham and Women's Hospital | 817337 | 2022-11-30 | 2025-11-10 | |
| The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma Atenolol Pill, Propranolol Pill - Spinal Tumor, Spinal Hemangioma | Phase 4 | Unknown | Center for Vascular Pathology, Moscow | 1000 | 2021-12-01 | 2021-11-03 |
| The Effect of Nitrendipine/Atenolol Combination on Blood Pressure Variability. Nitrendipine/Atenolol, Nitrendipine, Atenolol - Hypertension | Phase 4 | Unknown | Shanghai Jiao Tong University School of Medicine | 32 | 2021-09-27 | 2023-04-14 |
| Atenolol for the Prevention of Osteoporosis (APO) Atenolol 50 MG, Placebo - Healthy | Phase 2 | Completed | Sundeep Khosla, M.D. | 420 | 2021-07-27 | 2026-05-05 |
| Impact of Beta-blockers on Physical Function in HFpEF Beta blockers - Heart Failure, Heart Failure, Diastolic | Phase 4 | Completed | Weill Medical College of Cornell University | 9 | 2021-04-01 | 2023-09-08 |
| Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF Beta blockers - Heart Failure, Heart Failure, Diastolic | Phase 4 | Completed | Weill Medical College of Cornell University | 9 | 2021-04-01 | 2024-04-09 |
| Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy Labetalol, Atenolol, Nifedipine - Systolic Hypertension, Pregnancy Related | Recruiting | Marshall University | 60 | 2021-03-03 | 2025-05-13 | |
| Rate Control in Patients With Atrial Fibrillation Atenolol, Bisoprolol, Metoprolol, Nebivolol, Propranolol, Diltiazem, Verapamil, digoxin - Atrial Fibrillation, Rate Control | Not applicable | Completed | National Taiwan University Hospital | 13 | 2020-10-21 | 2026-01-16 |
| Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms Atenolol - Aneurysm | Not applicable | Unknown | Onassis Cardiac Surgery Centre | 424 | 2020-03-07 | 2020-01-13 |
| ACEI or ARB and COVID-19 Severity and Mortality in US Veterans ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID | Completed | University of Utah | 22213 | 2020-01-19 | 2021-04-28 | |
| 4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine 4-aminopyridine, Atenolol, Placebo - Vestibular Migraine, Migraine Disorders | Phase 2 | Withdrawn | Massachusetts Eye and Ear Infirmary | 2019-01-01 | 2024-07-01 | |
| TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion" Beta blocker - Myocardial Infarction | Phase 4 | Completed | Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III | 8505 | 2018-10-31 | 2025-06-06 |
| Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function Amlodipine, Losartan, Atenolol - Cerebral Small Vessel Diseases | Phase 3 | Terminated | Ludwig-Maximilians - University of Munich | 101 | 2018-02-22 | 2023-03-09 |
| Matão Controlling Hypertension (MatCH Study): Rationale and Design Captopril 25Mg, Hydrochlorothiazide 25Mg Oral Tablet,, Atenolol, Losartan potassium 50mg - Hypertension, Blood Pressure | Early Phase 1 | Unknown | Centro Neurológico de Pesquisa e Reabiitação, Brazil | 15000 | 2018-02-01 | 2017-11-21 |
| Impedance Cardiography to Decrease the Risk of Preeclampsia Labetalol Hydrocholoride 200 mg orally every 12 hours, Nifedipine 60 mg orally daily, Atenolol 25 mg daily - Chronic Hypertension Complicating Pregnancy (Diagnosis), Preeclampsia | Early Phase 1 | Withdrawn | University of Tennessee Medical Center | 2017-04-24 | 2020-08-05 |
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Hypertension (36) · Cardiovascular Diseases (7) · Heart Diseases (7) · Marfan Syndrome (7) · Atrial Fibrillation (5) · Motor Activity (5) · Diabetes Mellitus (4) · Heart Failure (4) · Angina Pectoris (3) · Atherosclerosis (3) · Coronary Disease (3) · Diabetes Mellitus, Type 2 (3) · Essential Hypertension (3) · Myocardial Ischemia (3) · Angina, Stable (2)
Brigham and Women's Hospital (3) · Mayo Clinic (3) · Mylan Bertek Pharmaceuticals (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Novartis (3) · Weill Medical College of Cornell University (3) · Emory University (2) · GlaxoSmithKline (2) · Merck KGaA, Darmstadt, Germany (2) · National Taiwan University Hospital (2) · Sandoz (2) · University of Florida (2) · University of Sao Paulo (2) · University of Vigo (2) · Ajou University School of Medicine (1)
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Betty S. Riggs, MD, MBA (2) · Parag Goyal, MD (2) · Ramon C Hermida, PhD (2) · Sundeep Khosla, MD (2) · Adam P Bress, PharmD, MS (1) · Ahmed M Shaat, MD (1) · Albert Oberman (1) · Alberto Forteza, Dr (1) · Amber L. Beitelshees, PharmD, MPH (1) · Andrew Ambrosy, MD, MPH (1) · Andrew Selwyn (1) · Arturo Evangelista, Dr (1) · Benjamin Epstein, Pharm.D. (1)
PMID 37565307, PMID 10639539, PMID 11403367, PMID 11897754, PMID 11937179, PMID 12135313, PMID 12172314, PMID 12423712, PMID 12493255, PMID 14581662, PMID 14639093, PMID 14656957, PMID 14700505, PMID 14704728, PMID 15716707, PMID 15879332, PMID 16448896, PMID 16476843, PMID 16942935, PMID 17179034, PMID 17253471, PMID 17337887, PMID 17444886, PMID 17485598, PMID 17510503, PMID 17637792, PMID 17762662, PMID 18268136, PMID 18464745, PMID 19104516, PMID 19249413, PMID 19300114, PMID 19407805, PMID 19486119, PMID 19571804, PMID 19628800, PMID 19792989, PMID 19817870, PMID 19842931, PMID 19850215, PMID 19917874, PMID 20047624, PMID 20228403, PMID 20555294, PMID 20606150, PMID 20725057, PMID 20838053, PMID 21127457, PMID 21183747, PMID 21306286
1UL1RR024975 (1), 2005 (1), 2025 (1), K23HL091120 (1), K76AG064428 (1), P01HL056693 (1), R01AG091005 (1), R01DK062030 (1), R01HL030171 (1), R01HL057529 (1), R01HL059459 (1), R01HL082638 (1), U01HL065962 (1), U01HL068270 (1)