61 completed, 10 unknown, 7 terminated, 2 not yet recruiting. 29 Not applicable, 27 Phase 4, 13 Phase 3, 5 Phase 2, 2 Early Phase 1.
Follow Hydroxyethyl Starch Derivatives: new trials by email Literature Review of Hydroxyethyl Starch Derivatives trials Research Report on Hydroxyethyl Starch Derivatives
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hydroxyethyl Starch Versus Crystalloid and Postoperative Major Adverse Kidney Complications Volulyte® (6% HES 130/0.4 in balanced solution), Crystalloid solutions - Cardiac Surgery | Phase 4 | Recruiting | Seoul National University Hospital | 1292 | 2026-06-22 | 2026-07-30 |
| Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients Hydroxyethyl starch 130/0.4, Lactate Ringer's Solution - Transcatheter Aortic Valve Replacement, Hemodynamic Stability | Not applicable | Not yet recruiting | Air Force Military Medical University, China | 116 | 2026-02-16 | 2026-02-27 |
| Safety and Efficacy of Perioperative Volume Replacement with Volulyte 6% in Moderate-to-high Cardiovascular Risk Patients Having Major Abdominal Surgery Hydroxyethyl starch 130/0.4, Sodium acetate Ringer - Perioperative Volume Replacement, Hydroxyethyl Starch | Phase 4 | Unknown | Xiangya Hospital of Central South University | 410 | 2024-11-30 | 2024-10-29 |
| Mild ANH on Pre-bypass Coagulation Function During Cardiac Surgery Acute normovolemic hemodilution (ANH), hydroxyethyl starch (HES 130/0.6) - Mitral Regurgitation, Mitral Stenosis | Not applicable | Not yet recruiting | Konkuk University Medical Center | 70 | 2024-10-28 | 2024-10-31 |
| 6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension Hydroxyethyl starch 130/0.4 - Adverse Effect | Not applicable | Unknown | General Hospital of Ningxia Medical University | 40 | 2024-02-01 | 2024-02-02 |
| Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial) Hydroxyethyl Starch 130/0.4 and Electrolyte injection of 5ml/kg, Multiple Electrolytes injection of 5 ml/kg - Postoperative Complications | Not applicable | Completed | Xijing Hospital | 2022 | 2023-07-12 | 2026-06-10 |
| Comparison of Hydroxyethyl Starch and Crystalloid Coload Combined With Norepinephrine Infusion for Hypotension Hydroxyethyl starch, Crystalloid - Adverse Effect | Not applicable | Completed | General Hospital of Ningxia Medical University | 80 | 2023-01-11 | 2023-03-22 |
| a Comparison Between the Effects of Crystalloids and Colloids on Lung Ultrasound hydroxyethyl starch in sodium chloride injection Brand Name: Voluven, saline solution - Pulmonary Edema | Early Phase 1 | Unknown | Kasr El Aini Hospital | 44 | 2022-12-05 | 2022-08-18 |
| Cardiac Output in Preeclamptic 1000 mL of ringer's acetate solution, 250 mL 6% hydroxyethyl starch (Voluven) then 500 mL of ringer's acetate solution then 250 mL of 6% hydroxyethyl starch (Voluven) - Echocardiography | Not applicable | Completed | Mansoura University | 34 | 2022-08-17 | 2026-02-17 |
| Effects of Crystal Solution and Colloid Solution on Mother and Fetus hydroxyethl starch, Lactated Ringer's solution - Cesarean Section, Spinal Anesthesia | Phase 4 | Completed | China International Neuroscience Institution | 100 | 2022-01-30 | 2022-12-01 |
| Days Alive and Out of Hospital for Patients With Sepsis Hydroxyethyl starch, Hydrocortisone, Early Goal Directed Therapy - Sepsis, Septic Shock | Completed | The George Institute for Global Health, Australia | 6213 | 2020-09-14 | 2024-02-23 | |
| The Potential Therapeutic Role of Hydroxyethyl Starch and Hydrocortisone in Acute Aluminum Phosphide Poisoning Hydroxyethyl Starch 130-0.4 60 MG/ML [Voluven], Hydrocortisone, Placebo - Potential Therapeutic Role | Not applicable | Completed | Tanta University | 60 | 2020-07-15 | 2024-05-01 |
| Safety and Efficacy of a 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Trauma Patients Volulyte 6%, Ionolyte - Hypovolemia Due to Acute Blood Loss | Phase 4 | Completed | Fresenius Kabi | 238 | 2019-02-23 | 2022-08-05 |
| Crystalloids Versus Colloids Versus Hypertonic Saline as a Co-load During Spinal Anesthesia. Normal saline, hydroxyethyl starch, Hypertonic saline - Spinal Anaesthesia | Not applicable | Completed | National Cancer Institute, Egypt | 120 | 2018-02-28 | 2018-09-24 |
| A Comparison of Eleview Versus Hetastarch as Injectate for EMR Eleview, Hetastarch - Procedural Bleeding, Delayed Bleeding | Phase 4 | Completed | Indiana University | 160 | 2017-10-09 | 2019-12-17 |
| Safety and Efficacy of 6% Hydroxyethyl Starch (HES) Solution Versus an Electrolyte Solution in Patients Undergoing Elective Abdominal Surgery Volulyte 6%, Ionolyte - Hypovolaemia Due to Acute Blood Loss | Phase 4 | Completed | Fresenius Kabi | 2289 | 2017-09-28 | 2024-01-31 |
| ROTEM Assessment of Modern Crystalloid, Hydroxyethyl Starch and Gelatin Effect on Coagulation hydroxyethyl starch - Coagulopathy | Completed | University Hospital, Motol | 30 | 2017-09-14 | 2025-02-25 | |
| Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study) 0.9% saline, HES 130/0.4 - Postoperative Morbidity, Postoperative Mortality | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 56 | 2017-08-01 | 2019-02-21 |
| The Effects of Intravenous Fluids on Perfusion Index and Pleth Variability Index sodium chloride, Hydroxyethylstarch, Ringer-Lactate Infusion Solution Bag - Perfusion | Not applicable | Completed | Tokat Gaziosmanpasa University | 93 | 2017-02-13 | 2017-05-16 |
| Endothelial Function After Cardiac Surgery Human albumin, Hydroxyethyl starch - Endothelial Dysfunction | Not applicable | Completed | The Cleveland Clinic | 85 | 2016-06-01 | 2024-02-01 |
Showing 20 of 81. Sign in to see all of them.
Hypotension (7) · Hemorrhage (3) · Hemostatic Disorders (3) · Ischemia (3) · Mitral Valve Insufficiency (3) · Mitral Valve Stenosis (3) · Postoperative Complications (3) · Sepsis (3) · Shock (3) · Shock, Septic (3) · Tricuspid Valve Insufficiency (3) · Burns (2) · Heart Valve Diseases (2) · Respiratory Aspiration (2) · Thrombosis (2)
Fresenius Kabi (8) · Seoul National University Hospital (4) · Konkuk University Medical Center (3) · Regional Hospital Holstebro (3) · Sangart (3) · General Hospital of Ningxia Medical University (2) · Kasr El Aini Hospital (2) · Medical University of Vienna (2) · The Cleveland Clinic (2) · Xijing Hospital (2) · Yonsei University (2) · Air Force Military Medical University, China (1) · Anders Perner (1) · Asan Medical Center (1) · Assiut University (1)
South Korea (14) · China (10) · United States (7) · Belgium (6) · Egypt (6) · Canada (5) · Czechia (5) · France (5) · Austria (4) · Denmark (4) · Germany (4) · Netherlands (4) · Poland (3) · Sweden (3) · United Kingdom (3)
Anne Sophie P. Kancir, MD PhD (3) · Wolfgang F. Buhre, Prof. Dr. med. (2) · Yi Chen, M.D. (2) · A. Gerson Greenburg, MD, Ph.D. (1) · Akiyoshi Namiki, MD, PhD (1) · Anders Perner, MD, PhD (1) · Andra Duncan, M.D. (1) · Anthony Senagore, MD (1) · Aynur Sahin, Dr (1) · Aysun Afife Kar, MD (1) · Buwei Yu, Prof. Dr. (1) · Chris Harle, MD (1) · Christina I. Olofsson, MD, PhD (1) · Daniel Sessler, M.D. (1)
PMID 30017128, PMID 18184958, PMID 19698859, PMID 20156348, PMID 21317165, PMID 21455059, PMID 21924634, PMID 22390818, PMID 22738085, PMID 23110412, PMID 23159133, PMID 23932181, PMID 24037226, PMID 24365167, PMID 24807084, PMID 24970272, PMID 25627076, PMID 25907781, PMID 27609188, PMID 28222674, PMID 29150842, PMID 30411246, PMID 31288028, PMID 31405567, PMID 31627889, PMID 32072617, PMID 32619039, PMID 32689849, PMID 32825817, PMID 33744114, PMID 33966019, PMID 34406128, PMID 35193648, PMID 35655234, PMID 38622671, PMID 41133731
2014 (1)