144 completed, 85 unknown, 40 recruiting, 18 active not recruiting. 140 Not applicable, 36 Phase 4, 23 Phase 3, 14 Phase 2, 1 Phase 1.
Follow Percutaneous Coronary Intervention: new trials by email Literature Review of Percutaneous Coronary Intervention trials Research Report on Percutaneous Coronary Intervention
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF Percutaneous coronary intervention, Guideline-directed medical therapy - Heart Failure With Reduced Ejection Fraction, Coronary Artery Disease | Not applicable | Not yet recruiting | Nanjing First Hospital, Nanjing Medical University | 1154 | 2026-12-30 | 2026-05-28 |
| International Study of Comparative Health Effectiveness With Medical and Invasive Approaches-Left Ventricular Dysfunction Trial Guideline-directed medical therapy (GDMT), Coronary artery bypass grafting (CABG), Percutaneous coronary intervention (PCI). - Coronary Artery Disease, Cognitive Impairment | Phase 3 | Suspended | NYU Langone Health | 1200 | 2026-12-01 | 2026-06-05 |
| Investigation to Assess the Effects of Drug-COATED Balloons for Treatment of Plaques Erosions Causing Acute Coronary Syndromes PCI with size matched DCB, GP IIbIIIa inhibitor or heparin & dual antiplatelet therapy - Myocardial Infarction, Percutaneous Coronary Intervention (PCI) | Not applicable | Not yet recruiting | 3W-Research Collaboration Group | 62 | 2026-10-01 | 2026-08-25 |
| iLITE, Clinical Performance of the Angiolite™ Drug-Eluting Stent Percutaneous Coronary Intervention - PCI Patients, de Novo Coronary Lesions | Not yet recruiting | iVascular S.L.U. | 5000 | 2026-10-01 | 2026-10-21 | |
| Minicrush Versus Culotte Stenting in Complex Coronary Bifurcation Lesions:The Multicenter T-REX II Registry Percutaneous Coronary Intervention with Minicrush - Coronary Artery Disease (CAD), Percutaneous Coronary Intervention (PCI) | Enrolling by invitation | San Luigi Gonzaga Hospital | 500 | 2026-09-01 | 2026-09-30 | |
| Comparative Evaluation of Sustained meChanical AsPiration Thrombectomy and no Thrombus Modification for Pre-stent Thrombus bUrden Reduction in Patients With Acute Myocardial Infarction Study: the CAPTURE AMI Study Sustained thrombectomy, Percutaneous Coronary Intervention - STEMI - ST Elevation Myocardial Infarction | Phase 2 / Phase 3 | Recruiting | Oxford University Hospitals NHS Trust | 60 | 2026-07-08 | 2026-07-10 |
| Overviewing Real-World Outcomes to Boost Interventional Management of CAlcified Coronary Lesions: the OROBICA Registry. Percutaneous coronary intervention with or without stent implantation - Coronary Artery Disease (CAD), Calcific Coronary Arteriosclerosis | Not yet recruiting | Papa Giovanni XXIII Hospital | 3000 | 2026-06-30 | 2026-05-06 | |
| Comparison of the Incidence of Major Cardiovascular Events Between the Combination of Percutaneous Intervention and Optimal Drug Therapy and the Optimal Drug Therapy Alone in Patients With Chronic Coronary Syndrome percutaneous coronary intervention, Guideline-directed Optimal Medical treatment, Carvedilol Sustained-Release (SR) (Nested RCT subset) - Chronic Coronary Syndrome | Not applicable | Not yet recruiting | Seoul National University Hospital | 2301 | 2026-06-15 | 2026-06-12 |
| CHIP-CC Registry: A Prospective Multicenter Registry of Complex High-Risk PCI in China Percutaneous Coronary Intervention, Mechanical Circulatory Support - Coronary Artery Disease, High Risk PCI | Not yet recruiting | Guofeng Gao | 1000 | 2026-06-01 | 2026-05-12 | |
| An Study Looking at Percutaneous Coronary Intervention Outcomes for Octogenarians Percutaneous Coronary Intervention - Cardio Vascular Disease | Not yet recruiting | Gloucestershire Hospitals NHS Foundation Trust | 850 | 2026-06-01 | 2026-06-08 | |
| Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome Percutaneous Coronary Intervention (PCI), Conservative Medical Therapy - ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI) | Recruiting | Clinical Center Niš | 550 | 2026-05-13 | 2026-05-15 | |
| Comprehensive Invasive Physiological Evaluation of Obstructive Coronary Artery Disease Coronary function testing, Percutaneous coronary intervention - Coronary Artery Disease (CAD), Obstructive Coronary Artery Disease | Not applicable | Not yet recruiting | UMC Utrecht | 450 | 2026-05-01 | 2026-05-01 |
| Development and Validation of a Multimodal Artificial Intelligence Model for Early Prediction of Acute Myocardial Infarction Percutaneous coronary intervention - Myocardial Infarction | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1500 | 2026-04-01 | 2026-03-09 | |
| Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease PCI with a bioresorbable scaffold and drug-coated balloon(s), PCI with drug-eluting stent(s) - Coronary Artery Disease, Diffuse Coronary Artery Disease | Not applicable | Recruiting | University Hospital, Geneva | 150 | 2026-04-01 | 2026-09-02 |
| Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction Percutaneous coronary intervention, Placebo procedure - Heart Failure With Preserved Ejection Fraction (HFPEF), Coronary Artery Disease | Phase 2 | Recruiting | King's College London | 350 | 2026-03-23 | 2026-05-01 |
| Bile Aspiration vs Drain in Acute Cholecystitis Gallbladder aspiration, Cholecystostomy - Cholecystitis, Acute | Not applicable | Not yet recruiting | Karolinska Institutet | 40 | 2026-03-01 | 2025-08-13 |
| The Coronary Sinus Balloon Pump in STEMI The coronary sinus balloon pump, Percutaneous Coronary Intervention (PCI) - STEMI | Not applicable | Not yet recruiting | Shanghai MicroPort Rhythm MedTech Co., Ltd. | 177 | 2026-02-12 | 2026-01-21 |
| Intravascular Imaging-Guided Intravascular Lithotripsy for Severe Coronary Calcified Lesions. percutaneous coronary intervention - Coronary Artery Calcification, Coronary Artery Disease | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 200 | 2026-02-10 | 2026-03-02 | |
| Study of Lesion-Specific Invasive Haemodynamic Angina Thresholds Percutaneous coronary intervention (PCI), Measurement of the angina threshold - Angina (Stable), Coronary Artery Disease(CAD) | Not applicable | Recruiting | Imperial College London | 60 | 2026-02-10 | 2026-10-19 |
| Intravascular Imaging-Guided Versus Angiography- Guided PCI in Patients With DES-ISR percutaneous coronary intervention - PCI, In-stent Restenosis | Recruiting | Nanjing First Hospital, Nanjing Medical University | 1500 | 2026-01-01 | 2025-12-22 |
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Coronary Artery Disease (158) · Myocardial Infarction (37) · Myocardial Ischemia (34) · ST Elevation Myocardial Infarction (33) · Acute Coronary Syndrome (29) · Coronary Disease (25) · Coronary Stenosis (22) · Angina, Stable (15) · Angina Pectoris (13) · Angina, Unstable (12) · Cardiovascular Diseases (12) · Diabetes Mellitus (9) · Heart Diseases (9) · Non-ST Elevated Myocardial Infarction (9) · Atherosclerosis (8)
Samsung Medical Center (8) · Assiut University (7) · Boston Scientific Corporation (7) · Nanjing First Hospital, Nanjing Medical University (7) · Seung-Jung Park (7) · Biotronik AG (6) · Yonsei University (6) · Elixir Medical Corporation (5) · Imperial College London (5) · San Luigi Gonzaga Hospital (5) · NYU Langone Health (4) · The First Affiliated Hospital with Nanjing Medical University (4) · Aarhus University Hospital Skejby (3) · Abbott Medical Devices (3) · Copenhagen University Hospital, Rigshospitalet (3)
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Shao-Liang Chen, MD (5) · Shigeru Saito, MD (4) · Leif Thuesen, MD (3) · Akiko Matsuo, MD (2) · Alessandro Lupi, MD (2) · Bon-Kwon Koo, MD, PhD (2) · Dean J Kereiakes, MD (2) · Evald H Christiansen, MD (2) · Gregg W Stone, MD (2) · Herman K Gold, MD (2) · Joo Myung Lee, MD, MPH, PhD (2) · Joo Myung Lee, MD, PhD (2) · Joo-Yong Hahn, MD, PhD (2) · Judith S Hochman, MD (2) · Louis A Cannon, MD (2)
PMID 37256598, PMID 38465592, PMID 20059766, PMID 23500281, PMID 26347918, PMID 27797291, PMID 28495897, PMID 30999989, PMID 31553204, PMID 32223567, PMID 34238026, PMID 35422242, PMID 36346059, PMID 36876735, PMID 38199751, PMID 39492702, PMID 42283075, PMID 42323001, PMID 10400006, PMID 10687202, PMID 11673337, PMID 12241831, PMID 12577841, PMID 12665484, PMID 1366259, PMID 14566249, PMID 14656913, PMID 14744976, PMID 14760193, PMID 16098418, PMID 16327043, PMID 16444619, PMID 16534015, PMID 16814667, PMID 16908490, PMID 17105848, PMID 17320742, PMID 17387127, PMID 17589978, PMID 17982182, PMID 18237682, PMID 18268144, PMID 18299505, PMID 18498953, PMID 18606919, PMID 18703470, PMID 19016466, PMID 19228612, PMID 19232907, PMID 19299430
2008 (1), R01HL067683 (1), R01HL149888 (1), U01HL071988 (1), U01HL105907 (1), U01HL117905 (1), U01HL125488 (1), U01HL125506 (1)