233 completed. 233 Phase 3, 32 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 233 | Completed 233 |
| Phase 2 | 32 | Completed 32 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TADCLOT- a Double Blind Randomized Controlled Trial Ticagrelor 90 MG, Clopidogrel - Stent Thrombosis, Myocardial Infarction, Acute | Phase 3 | Completed | National Institute of Cardiovascular Diseases, Pakistan | 2200 | 2024-02-19 | 2025-07-10 |
| Endovascular Treatment With or Without Preceding Intravenous Tenecteplase (TNK) in Patients With Late-window acUte Ischemic Stroke Due to Middle Cerebral Artery Occlusion Tenecteplase, direct EVT - Ischemic Stroke, Acute, Thrombolysis | Phase 3 | Completed | Beijing Tiantan Hospital | 391 | 2024-01-25 | 2025-11-26 |
| Evaluation in STEMI Patients Using FDY-5301 FDY-5301, Placebo - Acute Myocardial Infarction, STEMI | Phase 3 | Completed | Faraday Pharmaceuticals, Inc. | 2351 | 2022-05-02 | 2025-09-12 |
| Normoxemic Versus Hyperoxemic Extracorporeal Oxygenation in Patients Supported by Veino-arterial ECMO for Cardiogenic Shock Oxygen gas - Cardiogenic Shock, Extracorporeal Membrane Oxygenation | Phase 3 | Completed | Centre Hospitalier Universitaire de Besancon | 60 | 2022-01-09 | 2024-12-30 |
| Direct Oral Anticoagulants for Prevention of lEft ventRIcular Thrombus After Anterior Acute Myocardial InFarction - APERITIF Rivaroxaban 2.5 MG [Xarelto], DAPT strategy - Myocardial Infarction, Acute, Left Ventricular Thrombus | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 560 | 2021-10-10 | 2024-07-10 |
| Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients Dapagliflozin 10mg, Glucose Tab - Anterior MI | Phase 2 / Phase 3 | Completed | Omar Younis | 100 | 2021-10-01 | 2024-11-19 |
| MSCs for Prevention of MI-induced HF Umbilical Cord-Derived Wharton's Jelly Mesenchymal Stem Cells (WJ-MSCs), Conventional Treatment - Myocardial Infarction, Acute, Myocardial Infarction First | Phase 3 | Completed | Shiraz University of Medical Sciences | 420 | 2021-09-15 | 2024-11-04 |
| Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction GNR-060, Metalyse - ST Elevation Myocardial Infarction | Phase 3 | Completed | AO GENERIUM | 244 | 2021-09-03 | 2026-09-21 |
| LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients Levosimendan, Placebo of Levosimendan - Cardiogenic Shock, Extracorporeal Membrane Oxygenation Complication | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 206 | 2021-08-27 | 2025-03-21 |
| Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography Dapagliflozin 10Mg Tab, Placebo - Diabete Type 2, Unstable Angina | Phase 3 | Completed | Hilda Elizabeth Macías Cervantes | 54 | 2021-06-21 | 2023-08-21 |
| Platelet Inhibition With Ticagrelor 60 mg Versus Ticagrelor 90 mg in Elderly Patients With ACS Ticagrelor 90mg, Ticagrelor 60 mg - Acute Coronary Syndrome, STEMI | Phase 3 | Completed | Federico II University | 50 | 2021-04-01 | 2022-07-07 |
| Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack. Dapagliflozin, Placebo - Acute Myocardial Infarction, Heart Failure | Phase 3 | Completed | AstraZeneca | 4017 | 2020-12-22 | 2025-03-07 |
| EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction) Empagliflozin, Placebo - Myocardial Infarction | Phase 3 | Completed | Boehringer Ingelheim | 6522 | 2020-12-16 | 2025-01-07 |
| Rivaroxaban vErsus Warfarin for Antithrombotic TheRapy in Patients With LeFt Ventricular Thrombus After Acute STEMI Rivaroxaban 15 MG, Warfarin - Left Ventricular Thrombus, ST Segment Elevation Myocardial Infarction | Phase 3 | Completed | Rajaie Cardiovascular Medical and Research Center | 50 | 2020-07-30 | 2023-04-07 |
| The Effect of Colchicine on Inflammation in ACS Patients Colchicine Tablets - Acute Coronary Syndrome, STEMI | Phase 3 | Completed | Ain Shams University | 88 | 2020-02-01 | 2023-09-26 |
| Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD TQJ230, Placebo - Cardiovascular Disease and Lipoprotein(a) | Phase 3 | Completed | Novartis Pharmaceuticals | 8323 | 2019-12-12 | 2026-08-28 |
| Efficacy of Sovateltide (PMZ-1620) in Patients of Acute Ischemic Stroke Normal Saline along with standard treatment, PMZ-1620 (sovateltide) along with standard treatment - Cerebral Ischemia, Cerebral Infarction | Phase 3 | Completed | Pharmazz, Inc. | 158 | 2019-11-10 | 2023-10-18 |
| Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia Mexidol, Placebo - Chronic Cerebral Ischemia | Phase 3 | Completed | Pharmasoft | 318 | 2019-11-05 | 2025-10-06 |
| Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-2) NL003, Normal Saline - Arterial Occlusive Disease, Ischemia | Phase 3 | Completed | Beijing Northland Biotech. Co., Ltd. | 242 | 2019-08-28 | 2024-09-20 |
| Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1) NL003, Normal Saline - Arterial Occlusive Disease, Ischemia | Phase 3 | Completed | Beijing Northland Biotech. Co., Ltd. | 302 | 2019-08-02 | 2024-09-19 |
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Myocardial Infarction (150) · Cardiovascular Diseases (44) · ST Elevation Myocardial Infarction (41) · Heart Diseases (40) · Myocardial Ischemia (38) · Stroke (36) · Coronary Disease (27) · Acute Coronary Syndrome (26) · Coronary Artery Disease (23) · Heart Failure (19) · Angina, Unstable (18) · Cerebral Infarction (12) · Chronic Limb-Threatening Ischemia (10) · Angina Pectoris (9)
Pathological Conditions, Signs and Symptoms (233) · Pathologic Processes (232) · Vascular Diseases (225) · Necrosis (203) · Infarction (200) · Cardiovascular Diseases (187) · Heart Diseases (155) · Myocardial Ischemia (155) · Nervous System Diseases (49) · Brain Diseases (47) · Central Nervous System Diseases (47) · Cerebrovascular Disorders (43) · Signs and Symptoms (42) · Arteriosclerosis (39)
Clopidogrel (15) · Aspirin (11) · Ticagrelor (10) · Enoxaparin (8) · Prasugrel Hydrochloride (7) · Tissue Plasminogen Activator (7) · Heparin (6) · Tenecteplase (6) · Rivaroxaban (5) · Standard of Care (5) · Percutaneous Coronary Intervention (4) · Rosuvastatin Calcium (4) · Saline Solution (4) · bivalirudin (4) · Abciximab (3)
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PMID 35224730, PMID 34932836, PMID 41114449, PMID 19131498, PMID 20189026, PMID 23174632, PMID 24561145, PMID 25572507, PMID 26198286, PMID 27160944, PMID 27165710, PMID 27287251, PMID 11239408, PMID 12324494, PMID 12460865, PMID 12507972, PMID 14699020, PMID 15077099, PMID 15238590, PMID 15321804, PMID 15480537, PMID 15498829, PMID 15534844, PMID 15910853, PMID 15949912, PMID 16183441, PMID 16304073, PMID 16537663, PMID 16537665, PMID 16537725, PMID 16543037, PMID 16613998, PMID 16651474, PMID 16750696, PMID 16757723, PMID 16763187, PMID 16801465, PMID 16864722, PMID 16978651, PMID 16990384, PMID 17010793, PMID 17015064, PMID 17098754, PMID 17105759, PMID 17124018, PMID 17126719, PMID 17161253, PMID 17172279, PMID 17299194, PMID 17310025
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