27 completed, 10 unknown, 6 terminated, 2 withdrawn. 20 Phase 4, 12 Phase 3, 10 Phase 2, 3 Not applicable, 1 Phase 1.
Follow Abciximab: new trials by email Literature Review of Abciximab trials Research Report on Abciximab
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis Abciximab, Placebo, Intravenous hydration - Sickle Cell Disease, Hb-SS Disease With Vasoocclusive Pain | Phase 2 | Withdrawn | St. Louis University | 2013-11-01 | 2015-03-26 | |
| Exploratory P2 Trial to Evaluate Efficacy and Safety of Clotinab® (Abciximab) in Acute MI Patients Abciximab, Placebo - Acute Myocardial Infarction | Phase 2 | Unknown | ISU Abxis Co., Ltd. | 146 | 2013-05-01 | 2017-03-22 |
| A Randomized Trial of Intracoronary Reopro to Improve Coronary Microvascular Function Abciximab - Myocardial Infarction, Coronary Artery Disease | Not applicable | Unknown | University of Melbourne | 40 | 2012-02-01 | 2014-04-07 |
| Randomized Trial of Standard vs ClearWay-infused Abciximab and Thrombectomy for Myocardial Infarction ClearWay RX catheter, Abciximab - ST-elevation Myocardial Infarction | Phase 4 | Unknown | CLI Foundation | 128 | 2011-12-01 | 2012-01-05 |
| Efficacy of Combination of IntraCoronary Bolus Abciximab and Aspiration Thrombectomy in STEMI Gp 2b 3a inhibitor, aspiration thrombectomy, Both use - Acute Myocardial Infarction | Phase 4 | Completed | Yonsei University | 40 | 2010-12-01 | 2013-01-16 |
| Tailored Antiplatelet Therapy During Percutaneous Coronary Intervention in Patients With Diabetes Mellitus Abciximab, control - Diabetes Mellitus | Phase 4 | Completed | Seoul National University Bundang Hospital | 130 | 2010-09-01 | 2012-12-13 |
| Bivalirudin/Prasugrel Versus Abciximab/Clopidogrel in Patients Presenting With STEMI prasugrel/bivalirudin, clopidogrel/abciximab - ST-Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention | Phase 4 | Unknown | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | 800 | 2010-08-01 | 2010-07-08 |
| Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Intracoronary direct injection, Intracoronary and distal injection by aspiration device, Intracoronary distal injection by aspiration catheter device - Myocardial Infarction, Occlusive Thrombus | Phase 4 | Unknown | Hospital Virgen de la Salud | 186 | 2009-11-01 | 2012-02-22 |
| Comparative Study of ALX-0081 Versus GPIIb/IIIa Inhibitor in High Risk Percutaneous Coronary Intervention (PCI) Patients ALX-0081, ReoPro® - Unstable Angina, Non ST Segment Elevation Myocardial Infarction (NSTEMI) | Phase 2 | Completed | Ablynx, a Sanofi company | 364 | 2009-09-01 | 2023-04-04 |
| Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction. glycoprotein IIb/IIIa inhibitor (abciximab) - Myocardial Infarction, Angioplasty | Phase 4 | Terminated | Seoul National University Hospital | 150 | 2009-08-01 | 2026-04-27 |
| Intracoronary Abciximab With Clearway Catheter Intracoronary bolus wtih ClearWay™RX catheter, IV abciximab - Acute Myocardial Infarction | Phase 3 | Terminated | Gennaro Sardella | 150 | 2009-06-01 | 2013-01-04 |
| Comparison of Intracoronary Versus Intravenous Abciximab in ST-segment Elevation Myocardial Infarction (CICERO) abciximab - ST-Elevation Myocardial Infarction | Not applicable | Unknown | University Medical Center Groningen | 534 | 2008-09-01 | 2010-09-08 |
| Efficacy of Early Administration of Clotinab in Acute Myocardial Infarction Clotinab - Myocardial Infarction | Phase 4 | Completed | Yonsei University | 786 | 2007-07-01 | 2010-05-04 |
| Aspirin Resistance and Percutaneous Coronary Intervention (PCI) Intravenous Glycoprotein inhibitor + ASA, Clopidogrel, Antiplatelet Therapy (ASA, Clopidogrel) - Stable Angina | Phase 2 | Completed | Icahn School of Medicine at Mount Sinai | 36 | 2007-04-01 | 2018-02-14 |
| A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI and Rescue-PCI Abciximab - Myocardial Infarction, Ischemia | Phase 4 | Completed | Olivier F. Bertrand | 74 | 2007-02-01 | 2013-05-08 |
| A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI Abciximab - Myocardial Infarction, Ischemia | Phase 4 | Completed | Laval University | 105 | 2007-02-01 | 2011-11-24 |
| Efficacy Of Eptifibatide Compared To Abciximab In Primary Percutaneous Coronary Intervention (PCI) For Acute ST Elevation Myocardial Infarction (STEMI) Abciximab, Eptifibatide - Infarction, Myocardial | Phase 3 | Completed | GlaxoSmithKline | 429 | 2006-10-01 | 2012-11-27 |
| Abciximab in Patients Undergoing Percutaneous Coronary Intervention for Cardiogenic Shock Abciximab - Shock, Cardiogenic | Phase 4 | Completed | Charles University, Czech Republic | 80 | 2006-09-01 | 2009-06-23 |
| Randomized Comparison of Abciximab Plus Heparin With Bivalirudin in Acute Coronary Syndrome Abciximab + UFH, Bivalirudin, Heparin - Myocardial Infarction, Coronary Disease | Phase 4 | Completed | Deutsches Herzzentrum Muenchen | 1721 | 2006-07-01 | 2012-05-08 |
| Efficacy Study on Early Versus Late Abciximab Administration During Primary Coronary Angioplasty abciximab - Myocardial Infarction | Phase 4 | Completed | University of Pisa | 110 | 2006-04-01 | 2011-11-16 |
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Myocardial Infarction (16) · ST Elevation Myocardial Infarction (6) · Stroke (5) · Angina, Unstable (4) · Coronary Disease (4) · Coronary Artery Disease (3) · Ischemia (3) · Ischemic Stroke (3) · Angina, Stable (2) · Carotid Stenosis (2) · Non-ST Elevated Myocardial Infarction (2) · Acute Disease (1) · Anemia, Sickle Cell (1) · Angina Pectoris (1) · Arterial Occlusive Diseases (1)
Centocor, Inc. (5) · Deutsches Herzzentrum Muenchen (4) · Laval University (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · University Hospital Tuebingen (2) · University of Zurich (2) · Yonsei University (2) · Aarhus University Hospital Skejby (1) · Ablynx, a Sanofi company (1) · Azienda Sanitaria Ospedaliera (1) · Boehringer Ingelheim (1) · CLI Foundation (1) · Catharina Ziekenhuis Eindhoven (1) · Charles University, Czech Republic (1) · Emory University (1)
Germany (11) · Italy (8) · United States (7) · South Korea (5) · Canada (4) · Netherlands (4) · Switzerland (4) · Austria (3) · Czechia (3) · Denmark (3) · France (3) · Belgium (2) · Israel (2) · Poland (2) · Spain (2)
Adnan Kastrati, MD (4) · Albert Schomig, MD (3) · Olivier F Bertrand, MD, PhD (3) · Gunnar Tepe, MD (2) · Ralf W. Baumgartner, MD (2) · Albert Schoemig, MD (1) · Allan Iversen, MD (1) · Andrew Wilson, MD PhD (1) · Anna S Petronio, MD (1) · Annapoorna S Kini, MD MRCP (1) · Arshed A Quyyumi, M.D. (1) · Dong-Ju Choi, MD,PhD (1) · Felix Zijlstra, MD PhD (1)
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