2056 completed, 897 unknown, 487 recruiting, 238 terminated. 1255 Not applicable, 470 Phase 2, 426 Phase 4, 423 Phase 3, 194 Phase 1.
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease FGF-1, Placebo - Peripheral Arterial Disease, Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 24 | 2028-10-15 | 2026-08-19 |
| Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal Neurostimulation tVNS session on the left earlobe, tVNS "SHAM" session the conchae aurea of the left ear - Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA) | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Saint Etienne | 64 | 2027-01-31 | 2026-10-23 |
| AI-based Decision Support in Acute Chest Pain AIDE-CP available - Myocardial Infarction, Chest Pain | Not applicable | Not yet recruiting | Region Skane | 4500 | 2027-01-18 | 2026-10-07 |
| Norwegian Danish Spontaneous Coronary Artery Dissection Exercise Study High intensity interval training (HIIT) - Spontaneous Coronary Artery Dissection, Myocardial Infarction (MI) | Not applicable | Enrolling by invitation | Oslo University Hospital | 120 | 2027-01-01 | 2026-08-25 |
| Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) INTENT Neural Interface System - Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS) | Not applicable | Recruiting | Johns Hopkins University | 5 | 2027-01-01 | 2026-10-09 |
| French Observatory on the Management of Cardiogenic Shock 2 Cardiogenic Shock | Not yet recruiting | French Cardiology Society | 1000 | 2027-01-01 | 2026-10-09 | |
| A Study of Microcirculatory Function in Type 2 Myocardial Infarction (T2MI) Coronary angiogram with coronary reactivity testing (CRT) - Myocardial Infarction, Coronary Microvascular Disease | Not yet recruiting | Mayo Clinic | 52 | 2027-01-01 | 2026-08-31 | |
| Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patients Undergoing PCI Empagliflozin (SGLT2i), dapagliflozin, Standard medical treatment - No Reflow Phenomenon, Reperfusion Injuries, Myocardial | Phase 2 | Not yet recruiting | Al-Azhar University | 100 | 2027-01-01 | 2026-10-27 |
| The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), Aspirin Tablet - Cerebral Infarction | Phase 1 | Suspended | Sclnow Biotechnology Co., Ltd. | 40 | 2026-12-31 | 2026-04-23 |
| Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period. Allogeneic umbilical cord mesenchymal stem cell, Aspirin Enteric-coated Tablets & Atorvastatin Calcium - Cerebral Infarction | Phase 1 / Phase 2 | Suspended | Sclnow Biotechnology Co., Ltd. | 40 | 2026-12-31 | 2026-04-23 |
| Germany on Target Registry No study-assigned intervention - Myocardial Infarction (MI), Dyslipidemias | Not yet recruiting | Deutsche Gesellschaft für Lipidologie e. V. (DGFL) - Lipid-Liga | 10000 | 2026-12-01 | 2026-09-28 | |
| Hong Kong Cardiogenic Shock Initiative Cardiogenic Shock Acute, STEMI - ST Elevation Myocardial Infarction | Not yet recruiting | Prince of Wales Hospital, Shatin, Hong Kong | 320 | 2026-12-01 | 2026-09-16 | |
| Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study Biomarker testing - Peri-procedural Myocardial Infarction, Heart Failure Hospitalization | Not yet recruiting | Baim Institute for Clinical Research | 1000 | 2026-12-01 | 2026-09-30 | |
| Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia | Not yet recruiting | Spectrocor | 30 | 2026-12-01 | 2026-08-26 | |
| DCB Outcomes After Non-Compliant Balloon Vessel Preparation With or Without Scoring in Patients With Femoropopliteal Arterial Disease Non-compliant Plain Balloon angioplasty (PBA), Non-compliant Scoring Balloon Angioplasty (SB) - Femoropopliteal Disease, Drug Coated Balloon | Not applicable | Not yet recruiting | Marc Sirvent | 142 | 2026-12-01 | 2026-10-07 |
| PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease | Not yet recruiting | Medical College of Wisconsin | 60 | 2026-12-01 | 2025-10-14 | |
| Decompressive Craniectomy After Aneurysmal Subarachnoid Hemorrhage (DECIDE-SAH) Decompressive craniectomy - Aneurysmal Subarachnoid Hemorrhage | Not yet recruiting | University Hospital, Essen | 10000 | 2026-11-01 | 2026-10-14 | |
| Seltoplasmid Plus Revascularization for Diabetic Infrapopliteal Chronic Limb-Threatening Ischemia Lower-Extremity Revascularization, Donaperminogene Seltoplasmid - Chronic Limb-Threatening Ischemia, Diabetic Foot Ulcer | Phase 4 | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 180 | 2026-10-20 | 2026-09-18 |
| AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS) Acute Coronary Syndromes, Chest Pain | Not yet recruiting | University Medical Centre Maribor | 1000 | 2026-10-19 | 2026-10-20 | |
| Tenecteplase or Reteplase as Bridging Thrombolysis Before Thrombectomy in Acute Ischemic Cerebrovascular Events rhTNK-tPA (0.25mg/kg), Reteplase 10 Units (U) plus a second dose of reteplase 10 U, No thrombolysis (thrombectomy alone) - Acute Ischemic Stroke, Large Vessel Occlusion | Phase 3 | Recruiting | Yongjun Wang | 1440 | 2026-10-16 | 2026-10-22 |
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Myocardial Infarction (1962) · ST Elevation Myocardial Infarction (828) · Stroke (492) · Coronary Artery Disease (445) · Cardiovascular Diseases (357) · Chronic Limb-Threatening Ischemia (353) · Acute Coronary Syndrome (349) · Shock, Cardiogenic (289) · Non-ST Elevated Myocardial Infarction (283) · Heart Failure (256) · Myocardial Ischemia (235) · Cerebral Infarction (206) · Heart Diseases (203) · Coronary Disease (192)
Pathological Conditions, Signs and Symptoms (4149) · Pathologic Processes (4137) · Vascular Diseases (3904) · Cardiovascular Diseases (3659) · Necrosis (3405) · Infarction (3348) · Heart Diseases (2931) · Myocardial Ischemia (2858) · Myocardial Infarction (1038) · Arteriosclerosis (892) · Arterial Occlusive Diseases (891) · Nervous System Diseases (793) · Central Nervous System Diseases (757) · Brain Diseases (740)
Clopidogrel (92) · Aspirin (88) · Ticagrelor (79) · Percutaneous Coronary Intervention (76) · Standard of Care (51) · Saline Solution (37) · Sodium Chloride (37) · Prasugrel Hydrochloride (34) · Atorvastatin (33) · Heparin (29) · Abciximab (23) · Rivaroxaban (23) · Rosuvastatin Calcium (22) · Colchicine (21) · Tissue Plasminogen Activator (21)
National Heart, Lung, and Blood Institute (NHLBI) (68) · Assiut University (55) · Assistance Publique - Hôpitaux de Paris (44) · Insel Gruppe AG, University Hospital Bern (26) · Mayo Clinic (26) · University College, London (24) · Copenhagen University Hospital, Rigshospitalet (23) · University of Edinburgh (23) · Central Hospital, Nancy, France (22) · Karolinska Institutet (22) · Beijing Anzhen Hospital (21) · Oslo University Hospital (21) · AstraZeneca (20) · NYU Langone Health (20) · Samsung Medical Center (20)
United States (823) · China (425) · France (344) · Germany (301) · United Kingdom (271) · Canada (258) · Italy (245) · Spain (202) · Netherlands (199) · South Korea (164) · Denmark (156) · Poland (143) · Sweden (130) · Switzerland (124) · Belgium (114)
Harry Hemingway, FRCP (11) · Holger Thiele, MD (9) · Adnan Kastrati, MD (6) · Axel Bauer, MD (6) · David Antoniucci, MD (6) · Andreas M Zeiher, MD (5) · Georg Schmidt, MD (5) · Marc Bosiers, MD (5) · Petra Barthel, MD (5) · Antonio Colombo, MD (4) · Bon-Kwon Koo, MD, PhD (4) · Emily Herrett, MSc (4)
PMID 35224730, PMID 34932836, PMID 41114449, PMID 28886621, PMID 35802393, PMID 36526898, PMID 22163120, PMID 30538057, PMID 31242362, PMID 36398903, PMID 37131096, PMID 12939209, PMID 15673543, PMID 15778204, PMID 22995877, PMID 24876082, PMID 25593120, PMID 26347918, PMID 26794722, PMID 28286967, PMID 29386200, PMID 30354592, PMID 30586701, PMID 31733140, PMID 32905623, PMID 36303402, PMID 38682335, PMID 40014670, PMID 10460813, PMID 15956631, PMID 17090774, PMID 17223489, PMID 17387132, PMID 17964349, PMID 17982163, PMID 18036459, PMID 19118718, PMID 19131498, PMID 19264239, PMID 19359665, PMID 19717846, PMID 19915221, PMID 19923168, PMID 20189026, PMID 20348438, PMID 20359842, PMID 20736446, PMID 20929341, PMID 21079055, PMID 21146749
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