116 completed, 46 unknown, 33 recruiting, 14 terminated. 97 Not applicable, 25 Phase 2, 18 Phase 3, 16 Phase 4, 7 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Augmenting Clinical Workflow With a Structured Chatbot for Patient History Collection and Diagnostic Support AI-Based Structured History-Taking Chatbot - Medical History Taking, Artificial Intelligence in Clinical Workflow | Not yet recruiting | Massachusetts General Hospital | 100 | 2026-10-02 | 2026-10-07 | |
| Hyperspectral Imaging in Robot-Assisted Partial Nephrectomy Kidney Neoplasm, Renal Mass up to 7cm | Recruiting | University of Leipzig | 60 | 2026-09-01 | 2026-09-03 | |
| A-TANGO Phase 2 Study Placebo, TAK-242, G-CSF (Filgrastim) - Acute-On-Chronic Liver Failure, Alcoholic Hepatitis | Phase 2 | Recruiting | Yaqrit Ltd | 78 | 2026-06-29 | 2026-09-21 |
| ProspectiveMaleAYA - Frequency and Prediction of Therapy-induced Testicular Dysfunction in AYA Cancer Survivors Cancer, Reproduction | Not yet recruiting | Karolinska Institutet | 1000 | 2026-06-01 | 2026-05-29 | |
| Impact of Iridotomy/Iridectomy Size on Postoperative Pupillary Block and Dysphotopsia Following DMEK Anterior Segment Optical Coherence Tomography (AS-OCT), Dysphotopsia Questionnaire - Pupillary Block After DMEK, Laser Iridotomy / Surgical Iridectomy | Not yet recruiting | University of Leipzig | 100 | 2026-06-01 | 2026-07-02 | |
| A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer Risk profile disclosure - Barrett Esophagus, Barrett Esophagus Adenocarcinoma | Not applicable | Not yet recruiting | University Hospital, Antwerp | 266 | 2026-06-01 | 2026-03-06 |
| Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes Cancer, Infertility | Not yet recruiting | Karolinska Institutet | 4000 | 2026-06-01 | 2026-06-03 | |
| ProspectiveFemaleAYA - Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes Cancer, Cancer in Pregnancy | Not yet recruiting | Karolinska Institutet | 3000 | 2026-06-01 | 2026-06-03 | |
| Clinical Characterization of Patients With Primary Biliary Cirrhosis Treated With Seladelpar in the Real-life Setting Primary Bilary Cirrhosis (PBC) | Not yet recruiting | University of Leipzig | 100 | 2026-04-01 | 2026-04-24 | |
| Using Digital Twin Technology and Clinical Decision Support Systems to Improve the Early Detection, Personalised Treatment, and Long-term Monitoring of Patients Across the Full Spectrum of Metabolic-associated Fatty Liver Disease (MAFLD). Data recollection - Metabolic Dysfunction-Associated Steatotic Liver Disease | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 7720 | 2026-02-23 | 2026-02-24 | |
| REpeat Intervention For Failed Surgical BioProsthEtic AorTic Valves (REPEAT) Transfemoral transcatheter valve-in-valve implantation, Surgical redo aortic valve replacement - Degenerative Aortic Valve Disease | Not applicable | Recruiting | Heart Center Leipzig - University Hospital | 890 | 2025-11-10 | 2026-03-10 |
| Validation of Energy Expenditure Measures Study Obesity Prevention, Healthy | Recruiting | University of Leipzig | 49 | 2025-08-26 | 2026-09-14 | |
| A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer Endoscopic brush cytology - Barrett's Esophagus, Esophageal Adenocarcinoma | Not applicable | Recruiting | University Hospital, Antwerp | 50 | 2025-08-13 | 2026-02-24 |
| SmartWatch-driven AF Detection in Stroke Patients Wearable - Atrial Fibrillation (AF), Ischemic Stroke | Not applicable | Completed | University of Leipzig | 84 | 2025-05-15 | 2026-08-26 |
| A Contrast Medium Sparing Strategy Using Automated CO2 Injection During PVI for Prevention of Major Adverse Kidney Events (MAKE) CO2, Iodinated Contrast Media (ICM) - Peripheral Vascular Diseases, Kidney Diseases | Phase 3 | Recruiting | University of Leipzig | 1960 | 2025-04-14 | 2026-03-23 |
| Awake Prone Positioning in Spontaneous Breathing Patients With Acute Hypoxic Respiratory Failure Due to Pneumonia Awake Prone Positioning - Acute Hypoxemic Respiratory Failure | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 342 | 2025-04-11 | 2026-05-04 |
| Early TIPS in Patients With Liver Cirrhosis and Ascites Transjugular intrahepatic portosystemic shunt (TIPS) - Liver Cirrhosis, Ascites Hepatic | Not applicable | Recruiting | University Hospital Freiburg | 134 | 2025-04-01 | 2026-05-01 |
| EFFICACY OF INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION ON THE POSTOPERATIVE BLOOD LOSS IN PATIENTS UNDERGOING RARP FOR THE TREATMENT OF PROSTATE CANCER Arm A - Application of 5g of ARISTA™ AH - Prostate Cancer (Adenocarcinoma), Blood Loss, Postoperative | Not applicable | Recruiting | St. Antonius Hospital Gronau | 362 | 2025-01-16 | 2026-05-29 |
| Peripheral Drivers of Heart Failure Progression - The Prospective PEDAL-HF Study Heart Failure network care - Heart Failure - NYHA II - IV | Not applicable | Recruiting | University of Leipzig | 1000 | 2024-11-28 | 2026-05-06 |
| Design and Evaluation of a Team Timeout Checklist (TTOC) to Improve Information Exchange in the Operating Room Before Skin Incision Checklist, Teamwork | Completed | University of Jena | 151 | 2024-08-01 | 2025-09-24 |
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Obesity (16) · Heart Failure (10) · Coronary Artery Disease (9) · Neoplasms (9) · Myocardial Infarction (8) · Atrial Fibrillation (7) · Glucose Intolerance (5) · Obesity, Morbid (5) · ST Elevation Myocardial Infarction (5) · Sepsis (5) · Anemia (4) · Depression (4) · Heart Arrest (4) · Hypertension (4) · Inflammation (4)
Exercise (11) · Cognitive Behavioral Therapy (3) · Catheter Ablation (2) · Cytarabine (2) · Filgrastim (2) · Fluorouracil (2) · Granulocyte Colony-Stimulating Factor (2) · Hyperspectral Imaging (2) · Leucovorin (2) · Metformin (2) · Neoadjuvant Therapy (2) · Oxaliplatin (2) · Portasystemic Shunt, Transjugular Intrahepatic (2) · Ranibizumab (2) · Standard of Care (2)
Germany (205) · Austria (13) · United Kingdom (9) · Switzerland (8) · France (7) · Netherlands (6) · Italy (5) · Sweden (5) · Belgium (4) · Canada (3) · Denmark (3) · Ireland (3) · Israel (3) · Poland (3) · Spain (3)
Holger Thiele, MD (9) · Johannes Hebebrand, Prof. Dr. med. (5) · Martin Wabitsch, Prof. Dr. med. (5) · Susanna Wiegand, Dr. med. (5) · Thomas Reinehr, Prof. Dr. med. (5) · Wieland Kiess, Prof. Dr. med. (5) · Rainer P Hambrecht, MD (4) · Reinhard Holl, Prof. Dr. med. (4) · Gerhard Schuler, Professor (3) · Holger Thiele, Associate Professor (3) · Ines Gockel, Prof. Dr. (3) · Sirak Petros, MD (3) · Undine Pittl, MD (3) · Anne Sophie Kubasch, Dr. (2)
PMID 23987123, PMID 29122844, PMID 31278521, PMID 31329854, PMID 32335515, PMID 32873121, PMID 33083869, PMID 35851282, PMID 36268539, PMID 36384443, PMID 37046343, PMID 42749863, PMID 12356407, PMID 15273542, PMID 17426657, PMID 17823147, PMID 18555834, PMID 18559698, PMID 18924580, PMID 19433800, PMID 19539141, PMID 19920000, PMID 19962720, PMID 20362711, PMID 20430934, PMID 20435200, PMID 20466200, PMID 20510214, PMID 20675660, PMID 20856257, PMID 20950077, PMID 21059667, PMID 21091288, PMID 21279689, PMID 21298414, PMID 21309920, PMID 21345844, PMID 21403802, PMID 21511226, PMID 21710343, PMID 21724620, PMID 21860350, PMID 21920334, PMID 21990384, PMID 22015616, PMID 22068444, PMID 22080332, PMID 22108830, PMID 22216169, PMID 22267243
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