250 completed, 87 unknown, 26 recruiting, 19 terminated. 189 Phase 4, 83 Phase 3, 41 Phase 2, 38 Phase 1, 33 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-Term Dual Antiplatelet Therapy With Early Transi-tion to Low-dose Antiplatelet Monotherapy Using Ti-cagRelor in Chronic Coronary Artery Disease Ticagrelor 60 mg, clopidogrel 75 mg - Chronic Coronary Syndrome | Phase 4 | Not yet recruiting | University of Messina | 1000 | 2026-11-01 | 2026-09-15 |
| Dual Antiplatelet Therapy Strategies After Acute Myocardial Infarction Undergoing PCI: Prasugrel vs Ticagrelor & 12 Months vs 1-3 Months Prasugrel, Ticagrelor - Myocardial Infarction (MI) | Phase 4 | Recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 8100 | 2026-09-02 | 2026-09-09 |
| Ticagrelor-Based Dual Antiplatelet Therapy Duration in CABG Ticagrelor + Aspirin for 3 Months (followed by aspirin monotherapy), Ticagrelor + Aspirin for 6 Months (followed by aspirin monotherapy), Ticagrelor + Aspirin for 12 Months (followed by aspirin monotherapy) - Coronary Artery Disease, Coronary Artery Bypass Grafting | Not applicable | Not yet recruiting | Kexiang Liu, MD | 300 | 2026-05-01 | 2026-04-24 |
| Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty. Clopidogrel, Ticagrelor, Prasugrel - Coronary Artery Disease, Percutaneous Coronary Intervention | Phase 3 | Recruiting | Cardiocentro Ticino | 355 | 2026-04-20 | 2026-05-13 |
| Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone Ticagrelor + placebo, Ticagrelor + aspirin - NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI) | Phase 3 | Recruiting | Montreal Heart Institute | 2570 | 2026-03-03 | 2026-03-10 |
| Catequentinib Hydrochloride (AL3818) Drug-Drug Interaction Study in Healthy Volunteers AL3818 Capsule, Itraconazole capsule, Ticagrelor Tablets - Healthy Volunteer | Phase 1 | Not yet recruiting | Advenchen Laboratories Nanjing Ltd. | 16 | 2026-03-02 | 2026-02-27 |
| Aspirin 50mg vs 100mg Combined With P2Y12 Inhibitor After PCI Aspirin, P2Y12 inhibitor - Coronary Artery Disease, Acute Coronary Syndromes | Not applicable | Recruiting | Jilin University | 2640 | 2026-03-01 | 2026-10-01 |
| Use and Costs of P2Y12 Inhibitors After Acute Myocardial Infarction Clopidogrel, Prasugrel, Ticagrelor - Acute Myocardial Infarction (AMI) | Completed | Brigham and Women's Hospital | 377753 | 2025-11-01 | 2026-07-09 | |
| Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy in Symptomatic ICAD Point-of-Care CYP2C19 Testing, ticagrelor + aspirin, clopidogrel + aspirin - Intracranial Atherosclerosis | Not applicable | Recruiting | Sunnybrook Health Sciences Centre | 100 | 2025-10-07 | 2025-11-20 |
| Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study PFO closure using approved PFO closure devices, Surgical PFO closure, Medical management - Ischemic Stroke, Patent Foramen Ovale | Not yet recruiting | National University Hospital, Singapore | 1000 | 2025-07-01 | 2025-05-21 | |
| IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary Syndrome Indobufen, Aspirin, Ticagrelor - Coronary Artery Disease, Antiplatelet Drugs | Phase 4 | Recruiting | Shanghai Zhongshan Hospital | 2846 | 2025-05-19 | 2026-03-12 |
| Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery. Aspirin, Clopidogrel, Ticagrelor - Thrombosis, Bleeding | Active not recruiting | Petrovsky National Research Centre of Surgery | 500 | 2025-05-01 | 2026-01-22 | |
| Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease Aspirin, Clopidogrel, Ticagrelor - Peripheral Arterial Disease (PAD), Amputation | Not applicable | Recruiting | Massachusetts General Hospital | 484 | 2025-04-29 | 2026-09-11 |
| Comparative Bioavailability Study Between Ticagrelor and ASA Administered Individually or in Combination. A1: Ticagrelor / Acetylsalicylic acid in fixed dose combination capsule. (Laboratorios Silanes S.A. de C.V.), A2: Ticagrelor (BRILINTA®, AstraZeneca S.A. de C.V.) A3: Acetylsalicylic Acid (ASPIRINA JUNIOR®, Bayer de México S.A. de C.V.) - Healthy | Phase 1 | Completed | Laboratorios Silanes S.A. de C.V. | 24 | 2025-01-13 | 2026-03-02 |
| Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors Ticagrelor 90 mg, Prasugrel 10 mg - Coronary Artery Disease | Phase 4 | Recruiting | University of Florida | 48 | 2025-01-08 | 2026-02-05 |
| Colonoscopy and Antiplatelet Therapy Trial Aspirin, P2Y12 inhibitor (clopidogrel, ticagrelor, prasugrel) - Coronary Arterial Disease (CAD), Peripheral Vascular Disease | Phase 4 | Unknown | Ochsner Health System | 100 | 2024-10-01 | 2024-09-25 |
| Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects Tiprogrel, Clopidogrel, Ticagrelor - Acute Coronary Syndrome, Ischemic Stroke | Phase 1 | Completed | Tianjin Institute of Pharmaceutical Research Co., Ltd | 14 | 2024-09-09 | 2025-01-06 |
| Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA Ticagrelor 90 MG, Clopidogrel, Aspirin 75 Mg Oral Tablet - Ischemic Stroke | Phase 3 | Recruiting | Kafrelsheikh University | 900 | 2024-09-01 | 2025-09-05 |
| Ticagrelor Versus Cilostazol in Ischemic Stroke Ticagrelor 90 MG, Cilostazol 100 MG - Ischemic Stroke | Phase 3 | Unknown | Kafrelsheikh University | 900 | 2024-08-30 | 2024-08-20 |
| A Drug-drug Interaction Study of YZJ-1139 Tablets and Ticagrelor Tablets in Healthy Subjects YZJ-1139 tablets, Ticagrelor Tablets - Insomnia | Phase 1 | Completed | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | 27 | 2024-08-22 | 2026-06-30 |
Showing 20 of 407. Sign in to see all of them.
Coronary Artery Disease (99) · Acute Coronary Syndrome (90) · Myocardial Infarction (43) · ST Elevation Myocardial Infarction (37) · Cardiovascular Diseases (19) · Ischemic Stroke (19) · Thrombosis (18) · Angina, Unstable (14) · Diabetes Mellitus (14) · Coronary Disease (12) · Stroke (12) · Hemorrhage (11) · Atrial Fibrillation (10) · Non-ST Elevated Myocardial Infarction (10) · Peripheral Arterial Disease (10)
AstraZeneca (43) · University of Florida (20) · University of Patras (12) · First Affiliated Hospital of Harbin Medical University (10) · Kafrelsheikh University (10) · Collegium Medicum w Bydgoszczy (9) · Dong-A University (6) · Medical University of Vienna (6) · Assiut University (5) · Beijing Anzhen Hospital (5) · Ottawa Heart Institute Research Corporation (5) · Vastra Gotaland Region (4) · Beijing Tiantan Hospital (3) · Boehringer Ingelheim (3) · Brigham and Women's Hospital (3)
United States (98) · China (74) · South Korea (43) · Canada (33) · Italy (30) · United Kingdom (30) · Germany (27) · Poland (26) · Spain (26) · Netherlands (25) · France (21) · Greece (21) · Sweden (19) · Brazil (18) · Austria (17)
Dominick J Angiolillo, MD, PhD (6) · Dominick Angiolillo, MD, PhD (4) · Dominick J Angiolillo, MD,PhD (4) · Dimitrios Alexopoulos, MD (3) · Dominick Angiolillo (3) · Glenn Carlson, MD (3) · Jacek Kubica, MD., PhD. (3) · Juan J Badimon, PhD (3) · Judith Hsia, MD (3) · Kathleen Butler, MD (3) · Massoud Leesar, MD (3) · Anders Berggren, MD, PhD (2) · Chunjian Li, Ph.D (2)
PMID 35224730, PMID 31867054, PMID 19717846, PMID 2375765, PMID 27160944, PMID 40875095, PMID 18190818, PMID 19923168, PMID 20194878, PMID 30621974, PMID 34515113, PMID 11519503, PMID 15738352, PMID 16731270, PMID 20079528, PMID 21079055, PMID 21545948, PMID 21873419, PMID 22212857, PMID 22795280, PMID 23491524, PMID 23500251, PMID 24291273, PMID 24449597, PMID 24768873, PMID 25175921, PMID 25773268, PMID 27160892, PMID 29915123, PMID 30015064, PMID 31475799, PMID 31535314, PMID 33032710, PMID 33227548, PMID 34473343, PMID 36942550, PMID 37489818, PMID 11786451, PMID 11914403, PMID 12020339, PMID 12435254, PMID 12796140, PMID 12807523, PMID 12832332, PMID 14504252, PMID 14517152, PMID 14602724, PMID 15596563, PMID 15603245, PMID 16046311
2014 (7), 2015 (3), 2016 (3), 2023 (3), 2019 (2), 1OT2HL156812-01 (1), 2009 (1), 2017 (1), 2018 (1), R21AG077310 (1), U01HL128606 (1), U01NS117450 (1), U54MD010723 (1)