28 completed. 28 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 28 | Completed 28 |
| Phase 2 | 6 | Completed 6 |
Follow Hypoxia: new trials by email Literature Review of Hypoxia trials Research Report on Hypoxia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oxygen Targets in Acute Heart Failure With Pulmonary Congestion Oxygen - Acute Heart Failure, Pulmonary Congestion | Phase 2 / Phase 3 | Completed | Copenhagen University Hospital, Hvidovre | 135 | 2024-02-01 | 2026-10-26 |
| Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior Single Arm, Neonatal Neurobehavioral Scale - Congenital Heart Disease in Children, Hypoxia | Phase 2 / Phase 3 | Completed | University of Utah | 104 | 2021-12-17 | 2026-07-14 |
| EFFICACY and SAFETY OF BEVACIZUMAB (ZIRABEV®) IN PATIENTS WITH SEVERE HYPOXEMIC COVID-19 BEVA+SOC, SOC - Corona Virus Infection, SARS (Severe Acute Respiratory Syndrome) | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 96 | 2021-04-17 | 2022-12-28 |
| Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia Inhaled Low molecular weight heparin, Standard Treatment - COVID-19 Acute Respiratory Distress Syndrome, Hypoxemia | Phase 2 / Phase 3 | Completed | Istanbul University | 80 | 2021-02-03 | 2021-08-05 |
| CEUS Evaluation of Hypoxic Ischemic Injury Sulfur hexafluoride lipid-type A microspheres - Hypoxic-Ischemic Encephalopathy, Brain Ischemia Hypoxia | Phase 3 | Completed | Children's Hospital of Philadelphia | 1 | 2020-12-01 | 2025-05-14 |
| Higher vs. Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia Dexamethasone - Covid19, Hypoxia | Phase 3 | Completed | Scandinavian Critical Care Trials Group | 1000 | 2020-08-27 | 2022-02-24 |
| Hydrocortisone for COVID-19 and Severe Hypoxia Hydrocortisone, Sodium Chloride 9mg/mL - Covid-19, Hypoxia | Phase 3 | Completed | Scandinavian Critical Care Trials Group | 30 | 2020-04-17 | 2021-09-21 |
| An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19 Standard therapy recommended by the Ministry of Health of the Russian Federation., Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin intramuscular injection, Standard therapy recommended by the Ministry of Health of the Russian Federation and Leitragin inhalation - Acute Respiratory Tract Infection, Acute Respiratory Insufficiency | Phase 3 | Completed | Burnasyan Federal Medical Biophysical Center | 320 | 2020-04-08 | 2021-10-13 |
| Treatment of COVID-19 Patients With Anti-interleukin Drugs Usual Care, Anakinra, Siltuximab - COVID-19 | Phase 3 | Completed | University Hospital, Ghent | 342 | 2020-04-03 | 2023-03-14 |
| Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia Mexidol, Placebo - Chronic Cerebral Ischemia | Phase 3 | Completed | Pharmasoft | 318 | 2019-11-05 | 2025-10-06 |
| DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy of HNSCC. Nimorazole - Head and Neck Squamous Cell Carcinoma, Radiotherapy | Phase 3 | Completed | Danish Head and Neck Cancer Group | 1252 | 2016-09-01 | 2026-11-02 |
| PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns Epoetin Alfa, Normal saline - Hypoxic-Ischemic Encephalopathy | Phase 3 | Completed | University of Sydney | 313 | 2016-05-14 | 2024-06-05 |
| Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns Hydrocortisone, Placebo - Hypoxic-Ischemic Encephalopathy, Asphyxia | Phase 2 / Phase 3 | Completed | Semmelweis University | 32 | 2016-02-01 | 2023-04-21 |
| FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study Treatment strategy: Non-invasive respiratory support delivered via high flow nasal cannula, Treatment strategy: Non-invasive respiratory support delivered via continuous positive airway pressure - Hypoxia, Respiratory Acidosis | Phase 2 / Phase 3 | Completed | Great Ormond Street Hospital for Children NHS Foundation Trust | 121 | 2015-11-01 | 2016-12-16 |
| Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion Arterial line, Motion - Healthy, Hypoxia | Phase 3 | Completed | Medtronic - MITG | 18 | 2014-11-01 | 2017-05-05 |
| Efficacy of Erythropoietin to Improve Survival and Neurological Outcome in Hypoxic Ischemic Encephalopathy erythropoietin Beta, Placebo - Hypoxic Ischemic Encephalopathy | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 120 | 2013-03-28 | 2025-11-20 |
| Capnography During Percutaneous Transhepatic Cholangiodrainage (PTCD) (HepaBreath) capnography - Apnea, Hypoxemia | Phase 3 | Completed | Technical University of Munich | 20 | 2010-08-01 | 2012-04-30 |
| Effects of Caffeine on Intermittent Hypoxia in Infants Born Preterm Caffeine citrate 6 mg/kg/day - Hypoxia | Phase 3 | Completed | American SIDS Institute | 98 | 2010-07-01 | 2015-03-17 |
| Capnography During Upper GI Endoscopy Capnography - Capnography as an Adjunct to Standard Monitoring During Midazolam and Propofol Sedation for Interventional Upper GI Endoscopy | Phase 3 | Completed | Ruhr University of Bochum | 170 | 2010-06-01 | 2011-11-22 |
| Capnography During ERCP Capnography, Standard monitoring - Hypoxemia, Complications | Phase 3 | Completed | Technical University of Munich | 242 | 2010-02-01 | 2012-08-24 |
Showing 20 of 28. Sign in to see all of them.
Hypoxia-Ischemia, Brain (7) · COVID-19 (3) · Hypoxia, Brain (3) · Apnea (2) · Asphyxia (2) · Cardiovascular Diseases (2) · Cerebrovascular Disorders (2) · Heart Defects, Congenital (2) · Heart Diseases (2) · Hypothermia (2) · Ischemia (2) · Premature Birth (2) · Respiratory Distress Syndrome (2) · Severe Acute Respiratory Syndrome (2)
Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (28) · Signs and Symptoms, Respiratory (28) · Brain Diseases (11) · Nervous System Diseases (11) · Vascular Diseases (11) · Cardiovascular Diseases (10) · Central Nervous System Diseases (10) · Respiratory Tract Diseases (10) · Brain Ischemia (8) · Cerebrovascular Disorders (8) · Hypoxia, Brain (7) · Pathologic Processes (7) · Lung Diseases (6)
Hydrocortisone (2) · Saline Solution (2) · Sodium Chloride (2) · hydrocortisone hemisuccinate (2) · Capnography (1) · Cardiac Surgical Procedures (1) · Cardiopulmonary Bypass (1) · Cardiopulmonary Resuscitation (1) · Dexamethasone (1) · Epoetin Alfa (1) · Hypothermia, Induced (1) · Interleukin 1 Receptor Antagonist Protein (1) · Nimorazole (1) · Oxygen (1) · Parturition (1)
Technical University of Munich (3) · Assistance Publique - Hôpitaux de Paris (2) · Scandinavian Critical Care Trials Group (2) · American SIDS Institute (1) · Boston Children's Hospital (1) · Burnasyan Federal Medical Biophysical Center (1) · Children's Hospital of Philadelphia (1) · Copenhagen University Hospital, Hvidovre (1) · Danish Head and Neck Cancer Group (1) · Fudan University (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Istanbul University (1) · Max-Planck-Institute of Experimental Medicine (1) · Medtronic - MITG (1) · NICHD Global Network for Women's and Children's Health (1)
United States (6) · Germany (5) · Denmark (4) · France (2) · Russia (2) · Australia (1) · Belgium (1) · China (1) · Hungary (1) · India (1) · New Zealand (1) · Singapore (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1)
Stefan von Delius, MD (2) · Abbot R. Laptook, MD (1) · Abhik Das, PhD (1) · Aida A. Yakupova, MD, Cand.Med.Sci (1) · Aleksandr Y. Malygin, MD, Dr.Med.Sci (1) · Alina S. Agafina, MD, Cand.Med.Sci (1) · Anders Perner, MD, PhD (1) · Andrey M. Alasheev, MD, Dr.Med.Sci (1) · Ayca Yildiz-Pekoz, PhD (1) · Barbara J. Stoll, MD (1) · Bart Lambrecht, MD, PhD (1) · Betty McEntire, PhD (1) · Brenda B. Poindexter, MD MS (1) · Dale L. Phelps, MD (1) · Elena V. Vostrikova, MD, Cand.Med.Sci (1)
PMID 12165594, PMID 16221780, PMID 17079582, PMID 18534246, PMID 18720323, PMID 18762517, PMID 18829776, PMID 19020525, PMID 19252411, PMID 19834012, PMID 19948631, PMID 20921569, PMID 21054515, PMID 21852153, PMID 21875911, PMID 22646631, PMID 24019415, PMID 24445955, PMID 26387012, PMID 26415090, PMID 27776752, PMID 28606907, PMID 29866165, PMID 30808770, PMID 31155392, PMID 3124102, PMID 32493441, PMID 33038899, PMID 33583027, PMID 33935163, PMID 34138478, PMID 34673895, PMID 34756178, PMID 34757439, PMID 35067914, PMID 35080773, PMID 35349129, PMID 35359168, PMID 35835616, PMID 37316785, PMID 40889642, PMID 40983658
M01RR000030 (1), M01RR000039 (1), M01RR000044 (1), M01RR000070 (1), M01RR000080 (1), M01RR000633 (1), M01RR000750 (1), M01RR006022 (1), M01RR007122 (1), M01RR008084 (1), M01RR016587 (1), R01HL041786 (1), U01HD043464 (1), U10HD021364 (1), U10HD021373 (1)