179 completed, 51 unknown, 33 terminated, 29 recruiting. 145 Not applicable, 57 Phase 4, 53 Phase 2, 44 Phase 3, 21 Phase 1.
Follow Oxygen: new trials by email Literature Review of Oxygen trials Research Report on Oxygen
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Initial Oxygen Concentration at Birth in Late-Preterm Infants 60% Oxygen Group - Infants will start in 60% oxygen, 30% Oxygen Group - Infants will start in 30% oxygen - Preterm Birth | Not applicable | Not yet recruiting | University of Alberta | 1520 | 2026-11-01 | 2026-09-10 |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Trcheal High-flow for Weaning From Mechanical Ventilation Oxygen therapy - Tracheostomy, Mechanical Ventilation | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2026-10-01 | 2026-07-20 |
| Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment Trazodone + positive airway pressure (PAP) therapy, Oxygen + positive airway pressure (PAP) therapy - Sleep Disordered Breathing, Able Bodied | Phase 4 | Recruiting | VA Office of Research and Development | 200 | 2026-09-16 | 2026-10-13 |
| Effect of Topical Oxygen and LED Light Therapy on Nipple Crack Topical oxygen therapy, LED light therapy - Breastfeeding, Newborn Infant | Not applicable | Not yet recruiting | Istanbul University - Cerrahpasa | 51 | 2026-09-15 | 2026-05-27 |
| Hyperbaric Oxygen Therapy for Perianal Fistulizing Crohn's Disease Not Responsive or Intolerant to Conventional Care: HYPNOTIC Pilot Study Oxygen Gas for Inhalation, Standard of care - Inflammatory Bowel Disease (IBD), Crohn Disease | Phase 1 / Phase 2 | Not yet recruiting | University of British Columbia | 54 | 2026-09-01 | 2026-08-26 |
| Normobaric Hyperoxia With Extended-Window Endovascular Therapy for Acute Ischemic Stroke (OPENS-EXTEND) Oxygen (Normobaric Hyperoxia), Sham Normobaric Hyperoxia, Endovascular Therapy - Stroke, Acute, Neuroprotection | Phase 3 | Not yet recruiting | Weifang Medical University | 314 | 2026-09-01 | 2026-07-21 |
| Gut Oxygen Therapy for Ischemic-Hypoxic Bowel Disease Oxygen (O2) -Sham group, Sham -Oxygen (O2) group - Chronic Ischemic-Hypoxic Enteropathy | Not applicable | Recruiting | The Second Hospital of Nanjing Medical University | 100 | 2026-08-02 | 2026-08-05 |
| A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia Oxygen, Room air - Pulmonary Hypertension | Phase 1 / Phase 2 | Withdrawn | Duke University | 2026-07-01 | 2026-09-03 | |
| Effect of Supplemental Oxygen Therapy on Neurocognitive Performance in Healthy Highlanders Supplemental oxygen therapy, Sham intervention - Neurocognition | Phase 4 | Not yet recruiting | University of Zurich | 50 | 2026-06-18 | 2026-06-16 |
| Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory. Hypoxia exposure, Oxygen administration, Air administration - Hypoxia, Hypoxia Brain | Not applicable | Not yet recruiting | Direction Centrale du Service de Santé des Armées | 50 | 2026-05-06 | 2026-05-13 |
| Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult High Flow Oxygen, Oxygen - Postoperative Pulmonary Complications (PPCs) | Not applicable | Recruiting | Region Stockholm | 200 | 2026-04-20 | 2026-05-14 |
| ORI-Guided FiO₂ Titration in Prone Spine Surgery: Impact on Postoperative Atelectasis Assessed by Lung Ultrasound Titrated Oxygen, Fixed oxygen - Atelectases, Postoperative Pulmonary, Prone Position | Not applicable | Completed | Ankara Etlik City Hospital | 76 | 2026-03-15 | 2026-10-23 |
| Endotype DIrected Treatment for OSA in Down Syndrome ato-oxy, Oxygen - Obstructive Sleep Apnea (OSA), Down Syndrome | Phase 4 | Recruiting | University of Arizona | 200 | 2026-03-14 | 2026-09-03 |
| Intracervical Balloon Placement With Nitrous Oxide Administration Nitrous oxide, Oxygen - Labor Pain, Induced; Birth | Phase 3 | Withdrawn | Jefferson Drapkin | 2026-03-01 | 2026-09-17 | |
| A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask - Overactive Bladder, Neurogenic Bladder | Phase 4 | Not yet recruiting | TriHealth Inc. | 96 | 2026-02-01 | 2026-02-04 |
| Application of Topical Oxygen Therapy Around Customized Healing Collar topical oxygen therapy - Soft Tissue, Healing Abutment Influence on Gingival Volume | Phase 4 | Recruiting | Cairo University | 6 | 2026-01-01 | 2026-02-03 |
| A Trial of Self-Adjusted Nitrous Versus Placebo During Office Vasectomy Nitrous Oxide, Oxygen - Vasectomy | Early Phase 1 | Recruiting | Alexandra J. Berger Eberhardt, MD | 50 | 2025-10-20 | 2025-11-24 |
| Cerebral Hemodynamic Effects of Oxygen and Antioxidants (CHEOXANT) Oxygen, Vitamin C (Ascorbic Acid) - Oxygen, Hyperoxemia | Not applicable | Completed | Erasme University Hospital | 13 | 2025-09-01 | 2026-05-19 |
| Oxygen Therapy in Diabetic Kidney Disease Oxygen Therapy - Diabetic Kidney Disease | Not applicable | Not yet recruiting | Assiut University | 80 | 2025-08-01 | 2025-05-06 |
Showing 20 of 319. Sign in to see all of them.
Pulmonary Disease, Chronic Obstructive (35) · Hyperoxia (25) · Hypoxia (21) · Pain (13) · Respiratory Insufficiency (9) · Sleep Apnea, Obstructive (9) · Anxiety Disorders (8) · Asthma (8) · Heart Failure (7) · Motor Activity (7) · Hypertension, Pulmonary (6) · Lung Diseases, Interstitial (6) · Sleep Apnea Syndromes (6) · Agnosia (5) · Neoplasms (5)
Medical University of Vienna (8) · University of Zurich (8) · Brigham and Women's Hospital (6) · The Cleveland Clinic (6) · Eastern Switzerland University of Applied Sciences (5) · Insel Gruppe AG, University Hospital Bern (5) · Schön Klinik Berchtesgadener Land (5) · Assistance Publique - Hôpitaux de Paris (4) · Bernardino Clavo, MD, PhD (4) · Duke University (4) · Shanghai Asclepius Meditec Inc. (4) · VA Office of Research and Development (4) · Air Liquide Santé International (3) · Boston Children's Hospital (3) · China Medical University, China (3)
United States (89) · France (21) · China (19) · Switzerland (19) · Canada (14) · Germany (13) · Sweden (13) · United Kingdom (13) · Denmark (12) · Spain (12) · Turkey (Türkiye) (12) · Italy (11) · Brazil (9) · Austria (7) · Belgium (7)
Bernardino Clavo, MD, PhD (4) · Konrad E Bloch, MD (4) · Alparslan Turan, M.D. (3) · Dominik P Guensch, MD (2) · Gerhard Garhofer, MD (2) · Heidi Rayala, MD, PhD (2) · Pedro G Serrano-Aguilar, MD, PhD (2) · Ramon Barajas (2) · Susmita Chowdhuri, MD MS (2) · Alexandra J Berger Eberheardt, MD (1) · Alice M Turner (1) · Alison C Bested, MD FRCPC (1)
PMID 27940278, PMID 9925082, PMID 10377201, PMID 10453854, PMID 10471601, PMID 10508815, PMID 10706500, PMID 10787112, PMID 11468903, PMID 12740261, PMID 12793914, PMID 14617262, PMID 16162707, PMID 16281648, PMID 16310554, PMID 16723037, PMID 17503959, PMID 1758616, PMID 17951621, PMID 18625667, PMID 1864100, PMID 18641094, PMID 19151054, PMID 19183804, PMID 19232893, PMID 19260079, PMID 19826023, PMID 20405117, PMID 20525717, PMID 20816546, PMID 20843247, PMID 21037955, PMID 21071527, PMID 21352660, PMID 21427067, PMID 21502457, PMID 21511500, PMID 21575276, PMID 21835837, PMID 21941649, PMID 22147778, PMID 22445187, PMID 22840231, PMID 23102757, PMID 23369112, PMID 23406077, PMID 23406914, PMID 23511678, PMID 23549581, PMID 23664767
2014 (4), 2018 (4), 2017 (2), 2019 (2), 1UM1HL113203-01A1 (1), 2004 (1), 2009 (1), 2015 (1), I01CX001789 (1), I01RD001576 (1), K23HD098315 (1), N01HR761971 (1), R01DA008391 (1), R01EB017337 (1), R01GM112871 (1)