2111 completed, 637 unknown, 387 recruiting, 206 terminated. 1811 Not applicable, 357 Phase 2, 218 Phase 3, 206 Phase 4, 198 Phase 1.
Follow Signs and Symptoms, Respiratory: new trials by email Literature Review of Signs and Symptoms, Respiratory trials Research Report on Signs and Symptoms, Respiratory
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia Ferrous sulfate 325mg - Right Ventricular Dysfunction, Hypoxia | Early Phase 1 | Not yet recruiting | University of Colorado, Denver | 5 | 2028-03-01 | 2026-04-29 |
| Chronic COUGH Management in Interstitial Lung DisEase Non-pharmacological cough control therapy, Healthy lifestyle - Interstitial Lung Disease, Chronic Cough | Not applicable | Not yet recruiting | Aveiro University | 60 | 2027-12-20 | 2025-01-20 |
| Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support Remote Management, Remote Monitoring Only - COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD | Not applicable | Not yet recruiting | Sir Run Run Shaw Hospital | 236 | 2027-08-01 | 2026-08-06 |
| Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment - Dysphagia, Critical Illness | Not applicable | Not yet recruiting | Vanderbilt University Medical Center | 120 | 2027-07-01 | 2026-10-14 |
| Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in Patients With ARDS Normal Saline, Centhaquine - Acute Respiratory Distress Syndrome (ARDS) | Phase 2 | Not yet recruiting | Pharmazz, Inc. | 80 | 2027-05-01 | 2026-09-17 |
| Intranasal Stem Cells to Treat Perinatal Brain Injury to Combat Cerebral Palsy MSC, marrow, Placebo - Perinatal Arterial Ischemic Stroke, Perinatal Asphyxia | Phase 2 / Phase 3 | Not yet recruiting | UMC Utrecht | 162 | 2027-04-01 | 2026-09-21 |
| Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. Mouth Tape - Mild Obstructive Sleep Apnea, Snoring | Phase 2 | Recruiting | Johns Hopkins University | 100 | 2027-03-01 | 2026-06-23 |
| Prevent Wheeze Trial Dexamethasone 0.6 mg/kilogram body weight single dose, Placebo - Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing | Phase 4 | Not yet recruiting | Norwegian University of Science and Technology | 486 | 2027-02-01 | 2026-10-05 |
| Endoscopic Treatment Informed consent, Eligibility criteria check, Randomisation - Stenoses, Dyspnea | Not applicable | Not yet recruiting | University Hospital, Toulouse | 96 | 2027-01-01 | 2026-07-27 |
| ER-VISION-AI Study Generative Pre-trained Transformer (GPT)-assisted multimodal visual language model (VLM) diagnostic support, Conventional emergency department diagnostic evaluation - Chest Pain, Dyspnea | Not applicable | Not yet recruiting | Ewha Womans University Mokdong Hospital | 1000 | 2027-01-01 | 2026-07-27 |
| Cell-Based Therapy for White Matter Repair in Periventricular Leukomalacia Investigational Combination Product - Periventricular Leukomalacia, White Matter Disease | Early Phase 1 | Withdrawn | MGAM LLC | 2027-01-01 | 2025-07-22 | |
| A Stepped Intervention for Coping With Dyspnea in Patients With Lung Cancer-Phase A (Open Pilot) INSPIRE - Dyspnea, Lung Cancer (Diagnosis) | Not applicable | Not yet recruiting | Massachusetts General Hospital | 10 | 2027-01-01 | 2026-07-29 |
| Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia - Cough, Vocal Cord Atrophy | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 200 | 2027-01-01 | 2026-06-16 |
| Effect Of Intracuff Dexamethasone On Postoperative Sore Throat In Patients Undergoing Laparoscopic Cholecystectomy Dexamethasone (0.1 mg/kg), Normal Saline (0.9% NaCl) - Postoperative Sore Throat, Cough, Hoarseness | Not applicable | Not yet recruiting | B.P. Koirala Institute of Health Sciences | 40 | 2027-01-01 | 2026-08-24 |
| HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport Advanced Respiratory Support During Patient Transport - Acute Respiratory Failure, Respiratory Insufficiency | Not yet recruiting | Medipol University | 565 | 2026-12-31 | 2026-09-04 | |
| Physiological Effect High-flow Tracheal Oxygen on Viscosity of Airway Mucus and Respiratory Effort in Patients Weaning From Invasive Mechanical Ventilation Oxygen therapy - Weaning From Mechanical Ventilation, Tracheostomy Weaning | Not applicable | Recruiting | Henrik Endeman | 20 | 2026-12-31 | 2026-10-01 |
| Spectroscopic Assessment of Tissue Oxygenation Changes in Plastic Surgical Flap Reconstructions Flap Ischemia, Hypoxia | Not yet recruiting | Spectrocor | 30 | 2026-12-01 | 2026-08-26 | |
| Bedside Cranial Ultrasound for Risk-Stratified Imaging in Pediatric Acute Brain Injury Acute Brain Injury, Traumatic Brain Injury | Not yet recruiting | Virginia Commonwealth University | 220 | 2026-11-30 | 2026-08-19 | |
| Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation The Supraglottic Oxygenation Via Oral Transtracheal Catheter Group, The Regular Nasal Cannula - Choledocholithiasis With Cholecystitis With Obstruction, Obstructive Jaundice | Not applicable | Not yet recruiting | Zhejiang University | 410 | 2026-11-12 | 2026-09-25 |
| Does the Timing of Insomnia Therapy (CBT-i) Impact the Usage and Compliance of Upper Airway Stimulation (UAS) Treatment of Obstructive Sleep Apnea (OSA) Digital Cognitive Behavioral Therapy (CBT-i)-COAST - Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea | Not applicable | Not yet recruiting | Thomas Kaffenberger | 100 | 2026-11-05 | 2026-09-24 |
Showing 20 of 3786. Sign in to see all of them.
Hypoxia (1020) · Dyspnea (880) · Cough (411) · Pulmonary Disease, Chronic Obstructive (334) · Apnea (260) · Hypoxia-Ischemia, Brain (243) · Respiratory Sounds (182) · Asthma (171) · Sleep Apnea, Obstructive (157) · Hypercapnia (149) · Respiratory Insufficiency (143) · Chronic Cough (138) · Sleep Apnea Syndromes (124) · Motor Activity (122) · Snoring (121)
Pathological Conditions, Signs and Symptoms (3786) · Signs and Symptoms (3777) · Respiratory Tract Diseases (2615) · Respiration Disorders (2177) · Lung Diseases (1013) · Pathologic Processes (936) · Nervous System Diseases (816) · Cardiovascular Diseases (649) · Lung Diseases, Obstructive (525) · Vascular Diseases (465) · Disease Attributes (448) · Central Nervous System Diseases (407) · Infections (384) · Brain Diseases (374)
Oxygen (52) · Saline Solution (48) · Sodium Chloride (43) · Continuous Positive Airway Pressure (31) · Exercise (27) · Noninvasive Ventilation (25) · Blood Specimen Collection (24) · Standard of Care (24) · caffeine citrate (24) · Dexamethasone (21) · Propofol (18) · Albuterol (17) · Budesonide (17) · Surveys and Questionnaires (16) · montelukast (16)
Assistance Publique - Hôpitaux de Paris (52) · Riphah International University (43) · University of Zurich (42) · Assiut University (31) · Mayo Clinic (25) · University of Florida (23) · Duke University (19) · University Hospital, Grenoble (19) · University of British Columbia (19) · University of California, San Francisco (19) · Seoul National University Hospital (18) · University of Alberta (18) · Johns Hopkins University (17) · Laval University (17) · Imperial College London (16)
United States (980) · France (300) · Canada (257) · Turkey (Türkiye) (236) · United Kingdom (202) · China (192) · Germany (128) · Spain (115) · Italy (107) · Switzerland (102) · Belgium (93) · Netherlands (89) · Denmark (82) · Pakistan (80) · South Korea (78)
Silvia Ulrich, Prof. Dr. (16) · Philip Bickler, MD, PhD (11) · Rodrigo Hoyos (9) · Silvia Ulrich (9) · David Hui, MD (8) · Dennis Jensen, Ph.D. (7) · Denis E O'Donnell, MD, FRCPC (6) · Jordan A Guenette, PhD (5) · Konrad E Bloch, MD (5) · Michael Furian, Prof. Dr. (5)
PMID 24524452, PMID 12091180, PMID 26094920, PMID 35835616, PMID 10150800, PMID 10400005, PMID 11940739, PMID 12892358, PMID 12961065, PMID 14999112, PMID 15385385, PMID 16543552, PMID 17110415, PMID 17507545, PMID 18073550, PMID 19406289, PMID 19406290, PMID 20078243, PMID 20843245, PMID 21037472, PMID 21115606, PMID 21172990, PMID 21304242, PMID 21572329, PMID 21576107, PMID 21699998, PMID 21876461, PMID 22224835, PMID 22476448, PMID 22481227, PMID 22883447, PMID 22905352, PMID 23575612, PMID 24199628, PMID 25227281, PMID 26426314, PMID 26787799, PMID 26903337, PMID 27567470, PMID 28078544, PMID 28791567, PMID 28839984, PMID 28852473, PMID 28901969, PMID 29371379, PMID 30536725, PMID 3057957, PMID 31915621, PMID 31959019, PMID 32071135
2017 (11), 2015 (9), 2019 (9), 2018 (8), 2009 (7), 2023 (7), 2025 (7), 2016 (6), U10HD021364 (4), U10HD021373 (4), U10HD021385 (4), U10HD027851 (4), U10HD027853 (4), U10HD027856 (4), U10HD027880 (4)