3 unknown, 2 completed, 1 active not recruiting, 1 terminated. 4 Phase 3, 2 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Unknown 2, Completed 1, Terminated 1 |
| Not applicable | 2 | Active not recruiting 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Nimorazole: new trials by email Literature Review of Nimorazole trials Research Report on Nimorazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DAHANCA 37. Re-irradiation With Proton Radiotherapy Re-irradiation - Head and Neck Neoplasms | Not applicable | Unknown | Danish Head and Neck Cancer Group | 20 | 2019-09-01 | 2020-09-25 |
| Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma Intensity-Modulated Radiation Therapy (IMRT), Cisplatin, Nimorazole. - Oropharynx Cancer, Oropharynx Squamous Cell Carcinoma | Not applicable | Active not recruiting | Christian von Buchwald | 138 | 2019-03-01 | 2025-12-31 |
| DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy of HNSCC. Nimorazole - Head and Neck Squamous Cell Carcinoma, Radiotherapy | Phase 3 | Unknown | Danish Head and Neck Cancer Group | 1252 | 2016-09-01 | 2021-04-13 |
| NIMRAD (A Randomised Placebo-controlled Trial of Synchronous NIMorazole Versus RADiotherapy Alone in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Not Suitable for Synchronous Chemotherapy or Cetuximab) Nimorazole, Radiotherapy - Head and Neck Squamous Cell Carcinoma | Phase 3 | Completed | The Christie NHS Foundation Trust | 338 | 2014-09-11 | 2021-10-19 |
| AF CRT +/- Nimorazole in HNSCC Cisplatin, Radiotherapy, Placebo - Locally Advanced Head and Neck HPV Negative Squamous Cell Cancers | Phase 3 | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 640 | 2014-07-25 | 2022-05-10 |
| DAHANCA 28A: Phase I/II Study on Accelerated, Hyperfractionated Radiotherapy With Concomitant Cisplatin and Nimorazole 76 Gy/ 56 fx/ 10/W with cisplatin 40 mg/m2/W and nimorazole - HNSCC,Larynx, Pharynx and Oral Cavity | Phase 1 / Phase 2 | Completed | Danish Head and Neck Cancer Group | 31 | 2013-01-01 | 2017-07-28 |
| IAEA-HypoX. Accelerated Radiotherapy With or Without Nimorazole in Squamous Cell Carcinoma of the Head and Neck Accl. RT, Accl. radiotherapy + Nimorazole - Head and Neck Carcinoma | Phase 3 | Terminated | Danish Head and Neck Cancer Group | 104 | 2012-03-01 | 2016-11-25 |
Squamous Cell Carcinoma of Head and Neck (4) · Head and Neck Neoplasms (2) · Carcinoma (1) · Carcinoma, Squamous Cell (1) · DNA Virus Infections (1) · Hypoxia (1) · Laryngeal Diseases (1) · Neoplasms by Histologic Type (1) · Neoplasms by Site (1) · Neoplasms, Glandular and Epithelial (1) · Neoplasms, Squamous Cell (1) · Oropharyngeal Neoplasms (1) · Otorhinolaryngologic Diseases (1) · Otorhinolaryngologic Neoplasms (1) · Papillomavirus Infections (1)
Danish Head and Neck Cancer Group (4) · Christian von Buchwald (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · The Christie NHS Foundation Trust (1)
Denmark (4) · Australia (1) · Belgium (1) · Egypt (1) · Estonia (1) · France (1) · Germany (1) · Netherlands (1) · Pakistan (1) · Poland (1) · Slovenia (1) · Switzerland (1) · United Kingdom (1)
Christian von Buchwald, MD, DMSc. (1) · David Thomson (1) · Jens Overgaard (1) · Jens Overgaard, MD (1) · Jens Overgaard, MD DMSc (1) · Jens Overgaard, MD, DMSc (1) · Kenneth Jensen (1) · Mohamed Hassan, MD (1) · Niclas Rubek, MD (1)