17 completed, 3 terminated, 3 unknown, 1 not yet recruiting. 5 Not applicable, 4 Phase 3, 3 Phase 2, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Unknown 3, Completed 1, Not yet recruiting 1 |
| Phase 3 | 4 | Completed 4 |
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Cardiopulmonary Bypass: new trials by email Literature Review of Cardiopulmonary Bypass trials Research Report on Cardiopulmonary Bypass
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Effectiveness of Ultrasound-Guided Stellate Ganglion Block in Cardiac Surgery Anesthesia on Postoperative Recovery Elective surgery (≥ 24 hours) with cardiopulmonary bypass (more than 2 procedures) - Undergo Elective Cardiac Surgery, Cardiopulmonary Bypass | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Dijon | 250 | 2026-07-01 | 2026-07-23 |
| Optimization Strategy for Oxygen Delivery Under Cardiopulmonary Bypass Cardiopulmonary bypass - Cardiac Surgery | Terminated | University Hospital, Lille | 6 | 2023-10-03 | 2026-05-22 | |
| Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery blood use for priming cardiopulmonary bypass circuit, clear prime for cardiopulmonary bypass - Congenital Heart Disease | Not applicable | Unknown | Augusta University | 150 | 2023-05-10 | 2023-06-01 |
| Predictive Pre and Peroperative Factors for MODS-2 in Pediatric Cardiac Surgery Pediatric cardiac surgery with cardiopulmonary bypass - Congenital Heart Disease in Children, Cardiac Surgical Procedures | Completed | Brugmann University Hospital | 152 | 2022-03-18 | 2022-07-20 | |
| Vitamin B12a Vasoplegic Syndrome Hydroxocobalamin, Cardiopulmonary Bypass, Placebos - Vasoplegic Syndrome | Phase 2 | Terminated | Mayo Clinic | 8 | 2019-04-25 | 2023-05-10 |
| Cognitive and Speech Disorders in Children With Congenital Heart Defects Cardiovascular surgery with cardiopulmonary bypass - Cognition Disorder | Completed | Kemerovo State Medical University | 217 | 2019-03-01 | 2026-08-14 | |
| Transcatheter Aortic Valve Replacement With Extracorporeal Life System Support transcatheter aortic valve replacement - Aortic Stenosis, Aortic Regurgitation | Not applicable | Unknown | Xijing Hospital | 200 | 2018-08-01 | 2019-11-13 |
| Hematologic Ratios in Postoperative Acute Kidney Injury Cardiac Surgery with Cardiopulmonary Bypass - Acute Kidney Injury | Withdrawn | Children's Hospital Medical Center, Cincinnati | 2018-07-01 | 2024-11-06 | ||
| Bypass vs. Ecmo in Lung Transplantation (BELT) Extracorporeal Membrane Oxygenation, Cardiopulmonary Bypass - Lung Transplant; Complications | Terminated | The Cleveland Clinic | 13 | 2017-04-17 | 2020-03-24 | |
| Lung Protection and Pediatric Cardiac Surgery cardiopulmonary bypass - Lung Injury, Acute | Not applicable | Completed | Assiut University | 68 | 2017-01-01 | 2018-12-04 |
| Neutrophil, Lymphocyte and Platelet as a Predictor for AKI and Mortality Cardiovascular surgery with cardiopulmonary bypass - Acute Kidney Injury | Completed | Seoul National University Hospital | 1099 | 2016-04-01 | 2016-11-15 | |
| Heparin Based on Ideal Body Weight for Cardiopulmonary Bypass in Obese Patients Heparin, IV route, based on patients body weights (UI/kg), Cardiopulmonary bypass, Protamin administration - Cardiac Surgery, Cardiopulmonary Bypass | Phase 4 | Completed | University Hospital, Strasbourg, France | 60 | 2015-12-01 | 2026-03-16 |
| Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary Bypass Nitric Oxide, Standard CPB - Coronary Artery Disease, Coronary Artery Bypass | Phase 1 / Phase 2 | Completed | Tomsk National Research Medical Center of the Russian Academy of Sciences | 60 | 2015-05-15 | 2026-10-21 |
| The Predictability of Intraoperative Rotational Thromboelastometry on Postoperative Bleeding and Transfusion Requirements surgery for congenital heart disease with cardiopulmonary bypass - Surgery for Congenital Heart Disease, Pediatric Patients | Completed | Samsung Medical Center | 119 | 2014-01-01 | 2015-11-13 | |
| ECMO for Lung Transplantation in Cystic Fibrosis Patients Extracorporeal Life Support - Cystic Fibrosis | Completed | Policlinico Hospital | 80 | 2013-01-01 | 2019-04-18 | |
| NAG-excretion During Cardiopulmonary Bypass cardiopulmonary bypass - Renal Impairment | Completed | Sahlgrenska University Hospital | 65 | 2011-11-01 | 2016-03-08 | |
| Renal Perfusion, Filtration and Oxygenation During Cardiopulmonary Bypass (CPB) cardiopulmonary bypass - Complication of Extracorporeal Circulation, Renal Impairment | Completed | Sahlgrenska University Hospital | 28 | 2011-10-01 | 2019-05-07 | |
| Risk Factors for Delirium Following Cardiac Surgery Statin, beta blocker, Cardiopulmonary bypass - Delirium | Completed | Vanderbilt University | 5600 | 2009-11-01 | 2026-07-24 | |
| Anesthetic Management and Remote Reperfusion Injuries Cardiopulmonary bypass - Heart Valve Diseases | Completed | National Taiwan University Hospital | 40 | 2008-08-01 | 2011-10-17 | |
| Cardiopulmonary Bypass (CPB) Pumps and Blood Activation pumps used for cardiopulmonary bypass - Cardiopulmonary Bypass, Coronary Artery Disease | Not applicable | Unknown | University Hospital, Angers | 2005-01-01 | 2007-09-26 |
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Heart Defects, Congenital (6) · Heart Diseases (4) · Acute Kidney Injury (3) · Cardiovascular Diseases (3) · Coronary Artery Disease (2) · Hemorrhage (2) · Myocardial Ischemia (2) · Renal Insufficiency (2) · Transposition of Great Vessels (2) · Acute Lung Injury (1) · Aortic Valve Insufficiency (1) · Aortic Valve Stenosis (1) · Cerebrovascular Disorders (1) · Cognition Disorders (1) · Coronary Disease (1)
Sahlgrenska University Hospital (2) · Assiut University (1) · Augusta University (1) · Baystate Medical Center (1) · Boston Children's Hospital (1) · Brugmann University Hospital (1) · Centre Hospitalier Universitaire Dijon (1) · Children's Hospital Medical Center, Cincinnati (1) · Kemerovo State Medical University (1) · Maritime Heart Centre (1) · Mayo Clinic (1) · Michael Portman (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National Taiwan University Hospital (1) · Policlinico Hospital (1)
United States (6) · France (4) · South Korea (2) · Sweden (2) · Belgium (1) · Canada (1) · China (1) · Egypt (1) · Italy (1) · Russia (1) · Taiwan (1)
Christophe Baufreton, MD, PhD (1) · Denis Schmartz, MD (1) · Giacomo Grasselli (1) · James A. Nelson, M.B.B.S. (1) · Jane Newburger (1) · Jane W. Newburger, MD, MPH (1) · Jason O'Neal, M.D. (1) · Jean-Francois Legare, MD (1) · Michael Portman, MD (1) · Michael Tong, M.D., M.B.A. (1) · Sayed Abd-Elshafy, M.D (1) · Sergey V Popov, MD (1) · Shiqiang Yu, M.D. PH.D. (1) · Sven-Erik Ricksten, Professor (1)
PMID 18242267, PMID 19619781, PMID 20453699, PMID 20606124, PMID 20837917, PMID 21875911, PMID 27837950, PMID 28718100, PMID 29521662, PMID 31919012
2015 (1), R01HL041786 (1), R01HL048631 (1), U01HL063411 (1)