1392 completed, 447 unknown, 249 recruiting, 150 terminated. 1235 Not applicable, 180 Phase 3, 162 Phase 2, 118 Phase 4, 84 Phase 1.
Follow Premature Birth: new trials by email Literature Review of Premature Birth trials Research Report on Premature Birth
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Lower Blood Pressure One Year After Childbirth in Women Who Had Preeclampsia The intervention in the GESTA-SCORE study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs). - Adverse Pregnancy Outcomes, Cardiovascular Diseases | Not applicable | Not yet recruiting | Maternal-Infantil Vall d´Hebron Hospital | 150 | 2027-06-01 | 2026-11-03 |
| Pivotal Study to Assess Safety and Performance of Neola®, a Novel Lung Monitoring Device for Neonates Lung monitoring with the Neola device - RDS of Prematurity, Preterm Birth | Not applicable | Not yet recruiting | Neola Medical Inc | 22 | 2027-06-01 | 2026-11-12 |
| Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns Blood test - Congenital Hypothyroidism | Not yet recruiting | University Hospital, Lille | 1600 | 2027-03-01 | 2026-05-22 | |
| Little Lungs Study Calfactant, Budesonide - Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome | Phase 1 / Phase 2 | Not yet recruiting | University of Wisconsin, Madison | 24 | 2027-02-01 | 2026-11-02 |
| Strap To Reduce Apnea in Preterm Infants: A Randomized Crossover Trial Chinstrap - Apnea of Prematurity, Intermittent Hypoxemia | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 20 | 2027-01-15 | 2026-10-27 |
| Eye Tracking and Autism in Former Preterm Infants Eye-tracking device - Autism, Prematurity | Not applicable | Not yet recruiting | Indiana University | 40 | 2027-01-04 | 2026-08-14 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care Lateral, Prone, Incubator care - Kangaroo Care, Premature Infant | Not applicable | Not yet recruiting | Hospital Universitario 12 de Octubre | 314 | 2027-01-01 | 2026-03-16 |
| Evaluation of an Early Preventive and Educational Care Pathway for Moderate and Late Preterm Infants. A Randomized Controlled Study PREKINOU intervention - Infant, Premature | Not applicable | Not yet recruiting | University Hospital, Caen | 92 | 2027-01-01 | 2026-11-10 |
| Retinopathy of Prematurity - Visual Function and Retinal Structure Retinopathy of Prematurity (ROP), Prematurity Complications | Not yet recruiting | Oslo University Hospital | 140 | 2027-01-01 | 2026-11-10 | |
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-12-31 | 2026-10-30 |
| Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care Ultra-widefield Optical Coherence Tomography (UWF-OCT), Wide-field ophthalmic imaging system - Retinopathy of Prematurity (ROP) | Not applicable | Recruiting | Duke University | 175 | 2026-12-01 | 2026-09-17 |
| Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial Family-centered developmental training intervention - Preterm | Not applicable | Not yet recruiting | Seoul National University Hospital | 170 | 2026-12-01 | 2026-10-20 |
| Early Nutrition and Heart Structure and Function in Preterm Infants During the First Year of Life echocardiography - Cardiac Abnormalities, Nutrient Intake | Not yet recruiting | Assiut University | 80 | 2026-12-01 | 2026-11-05 | |
| nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 Weeks nCPAP-NAVA-backup mode, nCPAP mode - Apnea of Prematurity | Not applicable | Not yet recruiting | University Hospital, Geneva | 25 | 2026-12-01 | 2026-11-10 |
| Effect of Earmuffs on Physiological Stability, Sleep-Wake States, and Weight Gain in Preterm Neonates Neonatal Earmuffs - Preterm Infants | Not applicable | Not yet recruiting | University of Baghdad | 80 | 2026-11-20 | 2026-11-12 |
| NICU-to-Home Dyadic Support for Very Preterm Infants and Families Homebased SPEEDI, Telehealth SPEEDI - Preterm Birth, Very Preterm Infant | Not applicable | Not yet recruiting | University of Minnesota | 40 | 2026-11-16 | 2026-10-09 |
| Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up - Development Delay, Motor Skills Disorders | Not applicable | Not yet recruiting | Bengisu Boz Gürboğa | 36 | 2026-11-16 | 2026-10-21 |
| The Hemodynamic Impact of High-frequency Oscillatory Ventilation and Periodic Sighs in Preterm Infants Superimposed sigh breaths, High frequency ventilation - Preterm, Respiratory Distress Syndrome in Premature Infant | Not applicable | Not yet recruiting | Alexandria University | 100 | 2026-11-15 | 2026-10-27 |
| Neonatal AI-Based Early Warning System for Late-Onset Sepsis and Necrotizing Enterocolitis in the NICU: Assessment of Response and Effectiveness Intellicens Neo software - Late Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn | Not applicable | Not yet recruiting | University Hospital, Antwerp | 500 | 2026-11-09 | 2026-11-12 |
Showing 20 of 2538. Sign in to see all of them.
Bronchopulmonary Dysplasia (155) · Obstetric Labor, Premature (100) · Respiratory Distress Syndrome (94) · Enterocolitis, Necrotizing (78) · Breast Feeding (65) · Pre-Eclampsia (62) · Pain (58) · Apnea (47) · Respiratory Distress Syndrome, Newborn (45) · Pregnancy Complications (44) · Ductus Arteriosus, Patent (42) · Retinopathy of Prematurity (42) · Cerebral Palsy (37) · Fetal Growth Retardation (36)
Female Urogenital Diseases and Pregnancy Complications (2538) · Urogenital Diseases (2538) · Obstetric Labor Complications (2530) · Pregnancy Complications (2494) · Obstetric Labor, Premature (2438) · Pathological Conditions, Signs and Symptoms (555) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (438) · Respiratory Tract Diseases (375) · Signs and Symptoms (330) · Infant, Newborn, Diseases (321) · Lung Diseases (289) · Pathologic Processes (265) · Infant, Premature, Diseases (247) · Respiration Disorders (207) · Behavior (175)
Progesterone (37) · Standard of Care (31) · Saline Solution (27) · Umbilical Cord Clamping (22) · Control Groups (18) · Massage (17) · Music Therapy (17) · Cerclage, Cervical (16) · Sodium Chloride (16) · Kangaroo-Mother Care Method (15) · caffeine citrate (14) · Azithromycin (13) · Dexamethasone (13) · Ibuprofen (13) · Surveys and Questionnaires (13)
NICHD Neonatal Research Network (41) · University of Alabama at Birmingham (29) · Assistance Publique - Hôpitaux de Paris (26) · Ain Shams University (19) · University of Utah (18) · Christiana Care Health Services (17) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (16) · University of Pennsylvania (16) · Columbia University (15) · Children's Hospital of Fudan University (14) · Federico II University (14) · National Taiwan University Hospital (14) · Zekai Tahir Burak Women's Health Research and Education Hospital (14) · Centre Hospitalier Universitaire, Amiens (13) · Duke University (13)
United States (738) · Turkey (Türkiye) (247) · France (203) · Canada (137) · Italy (117) · United Kingdom (99) · China (79) · Egypt (76) · Israel (72) · Spain (72) · Germany (68) · Belgium (42) · Brazil (41) · Netherlands (34) · Switzerland (34)
Seetha Shankaran, MD (32) · Barbara J. Stoll, MD (27) · Richard A. Ehrenkranz, MD (25) · Waldemar A. Carlo, MD (21) · Abhik Das, PhD (19) · Edward F. Donovan, MD (18) · Abbot R. Laptook, MD (17) · David K. Stevenson, MD (15) · James A. Lemons, MD (14) · Jon E. Tyson, MD MPH (14) · Sheldon B. Korones, MD (14) · William Oh, MD (14) · Avroy A. Fanaroff, MD (13) · Charles R. Bauer, MD (13) · Krisa P. Van Meurs, MD (13)
PMID 35947046, PMID 33305842, PMID 33006765, PMID 35921693, PMID 36453699, PMID 28235686, PMID 29872859, PMID 30741812, PMID 39147903, PMID 10429008, PMID 10835060, PMID 11430325, PMID 12114906, PMID 14510324, PMID 14520225, PMID 14523165, PMID 15060228, PMID 15286223, PMID 15507925, PMID 15520109, PMID 15547163, PMID 15713907, PMID 15741371, PMID 15741374, PMID 15930228, PMID 15956871, PMID 15973322, PMID 15995042, PMID 16000352, PMID 16027695, PMID 16107873, PMID 16143580, PMID 16322158, PMID 16396864, PMID 16507341, PMID 16549503, PMID 16585322, PMID 16598294, PMID 16615955, PMID 16647401, PMID 16769377, PMID 16818526, PMID 16982497, PMID 17296783, PMID 17403821, PMID 17586184, PMID 17606555, PMID 17908750, PMID 17961693, PMID 17984212
U10HD021385 (34), U10HD027880 (32), U10HD027851 (31), U10HD027853 (30), U10HD027904 (30), U10HD021364 (29), U10HD021373 (29), U10HD027856 (28), U10HD027871 (26), U10HD034216 (25), M01RR008084 (23), U10HD021397 (21), M01RR000070 (20), U10HD040689 (20), M01RR000750 (19)