1378 completed, 453 unknown, 239 recruiting, 150 terminated. 1221 Not applicable, 180 Phase 3, 162 Phase 2, 117 Phase 4, 84 Phase 1.
Follow Premature Birth: new trials by email Literature Review of Premature Birth trials Research Report on Premature Birth
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of an Intensified Systematic Screening for Congenital Hypothyroidism in Premature Newborns Blood test - Congenital Hypothyroidism | Not yet recruiting | University Hospital, Lille | 1600 | 2027-03-01 | 2026-05-22 | |
| Eye Tracking and Autism in Former Preterm Infants Eye-tracking device - Autism, Prematurity | Not applicable | Not yet recruiting | Indiana University | 40 | 2027-01-04 | 2026-08-14 |
| The NEU - CAP Trial Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation - Infant, Premature, Diseases, Birth, Preterm | Not applicable | Not yet recruiting | Leiden University Medical Center | 1860 | 2027-01-01 | 2026-08-10 |
| Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care Lateral, Prone, Incubator care - Kangaroo Care, Premature Infant | Not applicable | Not yet recruiting | Hospital Universitario 12 de Octubre | 314 | 2027-01-01 | 2026-03-16 |
| Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care Ultra-widefield Optical Coherence Tomography (UWF-OCT), Wide-field ophthalmic imaging system - Retinopathy of Prematurity (ROP) | Not applicable | Recruiting | Duke University | 175 | 2026-12-01 | 2026-09-17 |
| Efficacy of a Video-based, Parent-centered Home Developmental Intervention for Infants at High Risk for Developmental Delay: a Multicenter Randomized Controlled Trial Family-centered developmental training intervention - Preterm | Not applicable | Not yet recruiting | Seoul National University Hospital | 170 | 2026-12-01 | 2026-10-20 |
| NICU-to-Home Dyadic Support for Very Preterm Infants and Families Homebased SPEEDI, Telehealth SPEEDI - Preterm Birth, Very Preterm Infant | Not applicable | Not yet recruiting | University of Minnesota | 40 | 2026-11-16 | 2026-10-09 |
| Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up - Development Delay, Motor Skills Disorders | Not applicable | Not yet recruiting | Bengisu Boz Gürboğa | 36 | 2026-11-16 | 2026-10-21 |
| Initial Oxygen Concentration at Birth in Late-Preterm Infants 60% Oxygen Group - Infants will start in 60% oxygen, 30% Oxygen Group - Infants will start in 30% oxygen - Preterm Birth | Not applicable | Not yet recruiting | University of Alberta | 1520 | 2026-11-01 | 2026-09-10 |
| PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled Tiotropium tiotropium bromide (Spiriva Respimat) - Bronchial Obstruction, Premature Birth | Phase 4 | Not yet recruiting | General University Hospital, Prague | 50 | 2026-11-01 | 2026-09-18 |
| Elevated Midline Positioning During Diaper Change in Preterm Infants 30-Degree Elevated Midline Positioning, Standard Lateral Position Diaper Change - Infant, Premature, Diseases, Premature Birth of Newborn | Not applicable | Not yet recruiting | Akdeniz University | 80 | 2026-11-01 | 2026-10-13 |
| Parent-Facilitated Early Oral-Sensory Experience in the NICU for Feeding Outcomes Parent-Facilitated Early Oral-Sensory Experience (PEOE) - Premature Birth, Infant, Premature | Not applicable | Not yet recruiting | Boston College | 60 | 2026-11-01 | 2026-10-20 |
| Postoperative Pain in Infants Postoperative Pain | Not yet recruiting | Uppsala University Hospital | 100 | 2026-10-30 | 2026-10-02 | |
| Cervical Stiffness in Women With Threatened Preterm Labor Pregnolia System - Preterm Labor, Preterm Birth | Recruiting | Pregnolia AG | 100 | 2026-10-15 | 2026-10-21 | |
| Effect of Automated Oxygen Control on Early-childhood Lung Mechanics Forced oscillometry technique - Prematurity, Respiratory Distress Neonatal | Not yet recruiting | King's College Hospital NHS Trust | 60 | 2026-10-12 | 2026-10-14 | |
| nCPAP Versus High-Flow Nasal Cannula in Preterm Infants With RDS Non-invasive respiratory support - Respiratory Distress Syndrome, Premature Birth | Not applicable | Not yet recruiting | Assiut University | 94 | 2026-10-10 | 2026-10-09 |
| Circadian-Synchronized Breast Milk Feeding and Sleep in Preterm Infants: A Multicenter Randomized Controlled Trial Circadian-Synchronized Breast Milk Feeding, Routine Breast Milk Feeding - Preterm Infant, Sleep | Not applicable | Not yet recruiting | Shanghai Jiao Tong University School of Medicine | 120 | 2026-10-08 | 2026-10-07 |
| A Study of Factors Associated With Failure of the Golden Hour Protocol in the Initial Care of Extremely Preterm and Very Low Birth Weight Newborns Golden hour - Prematurity; Extreme | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Nice | 50 | 2026-10-01 | 2026-09-21 |
| Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based Trial A package of oral health interventions, including a daily antiseptic oral rinse (alcohol-free cetylpyridinium chloride (0.075%)) - Preterm Birth, Low Birth Weight | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 2280 | 2026-10-01 | 2026-07-09 |
| AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone - Bacterial Vaginosis, Vaginal Dysbiosis | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 1794 | 2026-10-01 | 2026-08-27 |
Showing 20 of 2520. Sign in to see all of them.
Bronchopulmonary Dysplasia (152) · Obstetric Labor, Premature (100) · Respiratory Distress Syndrome (93) · Enterocolitis, Necrotizing (77) · Breast Feeding (64) · Pre-Eclampsia (62) · Pain (58) · Apnea (45) · Respiratory Distress Syndrome, Newborn (45) · Pregnancy Complications (44) · Ductus Arteriosus, Patent (42) · Retinopathy of Prematurity (42) · Cerebral Palsy (37) · Fetal Growth Retardation (36)
Female Urogenital Diseases and Pregnancy Complications (2520) · Urogenital Diseases (2520) · Obstetric Labor Complications (2512) · Pregnancy Complications (2476) · Obstetric Labor, Premature (2420) · Pathological Conditions, Signs and Symptoms (552) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (434) · Respiratory Tract Diseases (371) · Signs and Symptoms (328) · Infant, Newborn, Diseases (317) · Lung Diseases (285) · Pathologic Processes (263) · Infant, Premature, Diseases (244) · Respiration Disorders (205) · Behavior (171)
Progesterone (37) · Standard of Care (31) · Saline Solution (27) · Umbilical Cord Clamping (22) · Control Groups (18) · Music Therapy (17) · Cerclage, Cervical (16) · Massage (16) · Sodium Chloride (16) · Kangaroo-Mother Care Method (15) · caffeine citrate (14) · Azithromycin (13) · Ibuprofen (13) · Surveys and Questionnaires (13) · Utrogestan (13)
NICHD Neonatal Research Network (41) · University of Alabama at Birmingham (28) · Assistance Publique - Hôpitaux de Paris (26) · Ain Shams University (18) · University of Utah (18) · Christiana Care Health Services (17) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (16) · University of Pennsylvania (16) · Columbia University (15) · Children's Hospital of Fudan University (14) · Federico II University (14) · National Taiwan University Hospital (14) · Zekai Tahir Burak Women's Health Research and Education Hospital (14) · Centre Hospitalier Universitaire, Amiens (13) · Duke University (13)
United States (735) · Turkey (Türkiye) (244) · France (202) · Canada (137) · Italy (115) · United Kingdom (98) · China (78) · Egypt (75) · Spain (72) · Israel (71) · Germany (68) · Belgium (41) · Brazil (41) · Switzerland (33) · Denmark (32)
Seetha Shankaran, MD (32) · Barbara J. Stoll, MD (27) · Richard A. Ehrenkranz, MD (25) · Waldemar A. Carlo, MD (21) · Abhik Das, PhD (19) · Edward F. Donovan, MD (18) · Abbot R. Laptook, MD (17) · David K. Stevenson, MD (15) · James A. Lemons, MD (14) · Jon E. Tyson, MD MPH (14) · Sheldon B. Korones, MD (14) · William Oh, MD (14) · Avroy A. Fanaroff, MD (13) · Charles R. Bauer, MD (13) · Krisa P. Van Meurs, MD (13)
PMID 35947046, PMID 33305842, PMID 33006765, PMID 35921693, PMID 36453699, PMID 28235686, PMID 30741812, PMID 10429008, PMID 10835060, PMID 11430325, PMID 12114906, PMID 14510324, PMID 14520225, PMID 14523165, PMID 15060228, PMID 15286223, PMID 15507925, PMID 15520109, PMID 15547163, PMID 15713907, PMID 15741371, PMID 15741374, PMID 15930228, PMID 15956871, PMID 15973322, PMID 15995042, PMID 16000352, PMID 16027695, PMID 16107873, PMID 16143580, PMID 16322158, PMID 16396864, PMID 16507341, PMID 16549503, PMID 16585322, PMID 16598294, PMID 16615955, PMID 16647401, PMID 16769377, PMID 16818526, PMID 16982497, PMID 17296783, PMID 17403821, PMID 17586184, PMID 17606555, PMID 17908750, PMID 17961693, PMID 17984212, PMID 18166553, PMID 18245420
U10HD021385 (34), U10HD027880 (32), U10HD027851 (31), U10HD027853 (30), U10HD027904 (30), U10HD021364 (29), U10HD021373 (29), U10HD027856 (28), U10HD027871 (26), U10HD034216 (25), M01RR008084 (23), U10HD021397 (21), M01RR000070 (20), U10HD040689 (20), M01RR000750 (19)