51 completed. 51 Phase 1, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 51 | Completed 51 |
| Phase 2 | 13 | Completed 13 |
Follow Bipolar Disorder: new trials by email Literature Review of Bipolar Disorder trials Research Report on Bipolar Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective. Group A. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by anxiety disorders and depression., Group B. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by PTSD, Group C. The combination of pharmacotherapy and individual cognitive behavioral psychotherapy by obsessive-compulsive disorder. - Anxiety, Depression | Phase 1 | Completed | Rakitzi, Stavroula | 107 | 2025-06-02 | 2026-08-04 |
| A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode SEP-380135, Placebo - Schizophrenia, Major Depressive Disorder (MDD) | Phase 1 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 43 | 2024-11-07 | 2026-04-24 |
| A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD) ABBV-932, Placebo for ABBV-932 - Healthy Volunteers, Generalized Anxiety Disorder (GAD) | Phase 1 | Completed | AbbVie | 72 | 2023-08-31 | 2025-03-17 |
| Pentoxifylline for Treatment of Resistant Major Depression Pentoxifylline, Placebo - Resistant Major Depression | Phase 1 / Phase 2 | Completed | Hawler Medical University | 60 | 2021-12-15 | 2022-09-07 |
| Modeling Mood Course to Detect Markers for Effective Adaptive Interventions- Aim 3 Mobile intervention - Bipolar Disorder, Psychosocial Intervention | Phase 1 | Completed | University of Wisconsin, Madison | 30 | 2019-09-13 | 2022-01-03 |
| Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar Disorder Seroquel IR 300mg, Seroquel IR 25mg, Quetiapine Formulation A 300mg - Bipolar Disorder, Schizophrenia | Phase 1 | Completed | Otsuka Pharmaceutical Development & Commercialization, Inc. | 58 | 2019-03-27 | 2020-09-02 |
| Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial Ketamine, Perampanel, Placebo - Depressive Disorder, Major, Post Traumatic Stress Disorder | Phase 1 | Completed | Yale University | 13 | 2018-11-29 | 2025-02-07 |
| Technology Enhanced Family Treatment Family-Focused Treatment with MCC App - Mood Disorders, Bipolar Disorder | Phase 1 / Phase 2 | Completed | University of California, Los Angeles | 65 | 2018-11-15 | 2024-05-28 |
| Ketamine as an Adjunctive Therapy for Major Depression Ketamine, Midazolam - Major Depressive Episode, Unipolar Depression | Phase 1 | Completed | St Patrick's Hospital, Ireland | 25 | 2017-09-07 | 2020-01-18 |
| Differential Responses to Drugs and Sweet Tastes Placebo oral capsule, d-amphetamine 10 mg oral capsule, d-amphetamine 20 mg oral capsule - Bipolar II Disorder | Phase 1 | Completed | University of Chicago | 93 | 2017-02-09 | 2023-02-22 |
| Pharmacokinetics, Safety and Tolerability of Repeat Dosing Lamotrigine in Healthy Chinese Subjects Lamotrigine - Bipolar Disorder | Phase 1 | Completed | GlaxoSmithKline | 16 | 2015-09-06 | 2017-05-08 |
| Inositol Hexaphosphate: A Novel Treatment Strategy for Bipolar Disorder? IP6, Lamotrigine - Bipolar Disorder, Manic Depression | Phase 1 | Completed | San Diego Veterans Healthcare System | 8 | 2014-05-01 | 2018-08-01 |
| Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants Aripiprazole, oral formulation, Olanzapine, oral formulation, Paliperidone, oral formulation - Psychotic Disorders, Schizophrenia | Phase 1 | Completed | Janssen Research & Development, LLC | 305 | 2014-02-01 | 2015-10-29 |
| Ketamine for Suicidality in Bipolar Depression Ketamine, Midazolam - Bipolar Disorder, Major Depressive Episode | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 16 | 2013-09-01 | 2020-03-11 |
| Bio-equivalence Study Between SAPHRIS and Asenapine SAPHRIS, Asenapine - Schizophrenia, Bipolar Disorder | Phase 1 | Completed | Sun Pharmaceutical Industries Limited | 65 | 2013-07-01 | 2021-04-30 |
| Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders Mindfulness-based cognitive therapy - Major Depressive Disorder, Bipolar Disorder | Phase 1 | Completed | University of California, Los Angeles | 39 | 2012-10-01 | 2014-05-30 |
| Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults MagVenture MagPro MST, RUL ECT - Depression, Major Depressive Episode | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 18 | 2012-08-01 | 2020-09-03 |
| Nutrition, Exercise, and Wellness Treatment (NEW Tx) for Bipolar Disorder Nutrition, Exercise, and Wellness (NEW) psychotherapy, Typically consists of at least one FDA-approved mood stabilizer - Bipolar Disorder | Phase 1 / Phase 2 | Completed | Massachusetts General Hospital | 38 | 2012-05-21 | 2018-06-07 |
| Tolerability and Pharmacokinetics of Iloperidone in Adolescent Patients iloperidone (oral tablet) - Safety and Tolerability of Iloperidone | Phase 1 | Completed | Vanda Pharmaceuticals | 33 | 2011-10-01 | 2016-06-13 |
| Remediation of Cognitive Dysfunction in Euthymic Bipolar Disorder Patients Using Transcranial Direct Current Stimulation (tDCS) Transcranial direct current stimulation (Eldith DC Stimulator) - Bipolar Disorder | Phase 1 | Completed | The University of New South Wales | 15 | 2011-09-01 | 2015-11-03 |
Showing 20 of 51. Sign in to see all of them.
Schizophrenia (11) · Depression (8) · Depressive Disorder, Major (7) · Psychotic Disorders (5) · Alcoholism (3) · Depressive Disorder (3) · Epilepsy (3) · Anxiety Disorders (2) · Mood Disorders (2) · Seizures (2) · Stress Disorders, Post-Traumatic (2) · Substance-Related Disorders (2) · Behavior, Addictive (1) · Cocaine-Related Disorders (1)
Bipolar and Related Disorders (51) · Mental Disorders (51) · Mood Disorders (49) · Schizophrenia Spectrum and Other Psychotic Disorders (12) · Behavior (11) · Behavioral Symptoms (8) · Depressive Disorder (6) · Nervous System Diseases (6) · Chemically-Induced Disorders (5) · Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Alcohol-Related Disorders (3) · Brain Diseases (3) · Central Nervous System Diseases (3)
Valproic Acid (4) · Ketamine (3) · Lamotrigine (3) · 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (2) · Aripiprazole (2) · Lithium (2) · Midazolam (2) · Paliperidone Palmitate (2) · Risperidone (2) · Topiramate (2) · vixotrigine (2) · 3-(6-p-tolylpyridin-3-yloxy)-1-azabicyclo(2.2.2)octane (1) · Acamprosate (1) · Bupropion (1) · Carbamazepine (1)
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (4) · New York State Psychiatric Institute (3) · Otsuka Pharmaceutical Development & Commercialization, Inc. (3) · University of California, Los Angeles (3) · University of Miami (3) · Biogen (2) · Eli Lilly and Company (2) · GlaxoSmithKline (2) · Massachusetts General Hospital (2) · Pfizer (2) · Sandoz (2) · Yale University (2) · AbbVie (1) · AstraZeneca (1) · Dartmouth-Hitchcock Medical Center (1)
United States (34) · Singapore (3) · United Kingdom (3) · Argentina (1) · Australia (1) · Belgium (1) · Brazil (1) · Bulgaria (1) · China (1) · Germany (1) · Greece (1) · Iraq (1) · Ireland (1) · Israel (1) · Spain (1)
Ihsan M Salloum, MD, MPH (2) · Armen Arevian, MD (1) · Aude Henin, Ph.D. (1) · Barry F Chaitin, M.D. (1) · Bryan K. Tolliver, M.D., Ph.D. (1) · David A. Axelson, MD (1)
PMID 18762591, PMID 19454920, PMID 20854181, PMID 26187603, PMID 26682997, PMID 27371157, PMID 28379964, PMID 29063592, PMID 29578646, PMID 32965227, PMID 33360365, PMID 34131914, PMID 35036831, PMID 37079363, PMID 38094620, PMID 39428602, PMID 40109484, PMID 40494497
2016 (1), K01MH112876 (1), K24DA000435 (1), R01AA015385 (1), R01DA019992 (1), R01MH059710 (1), R21MH062555 (1), R34MH081335 (1), R34MH083894 (1), R34MH090148 (1), R34MH117200 (1)